Document yb7x9xXmxNgMZKvzk0MYRyDJV

FILE NAME: Mobil (MOB) DATE: 1961 DOC#: MOB002 DOCUMENT DESCRIPTION: Published Conference Proceedings with Donor List Proceedings THIRTEENTH INTERNATIONAL CONGRESS ON OCCUPATIONAL HEALTH LIST OF DONORS 1003 The following corporations, governmental agencies, labor unions, professional societies, and individuals contributed to the financial support of the Congress: AThFeL/AClIcOoa Foundation AMF Foundation AAdlldegrehsesnoygrLapuhd-lMumultSigterealpCh oCrpoorrpaotrioantion AAmllise-rCichaalFmoerresLMoyaanltuyfaGcrtuoruipng Company American Brake Shoe Company AAmmeerriiccaann CCaasnt CIroomnpPainpye Company American Cyanamid Company American Industrial Hygiene Association Am(NeroirctahnerMn eCdaicliaflorAnsisaocSieacttiioonn) AAmmeerriiccaann MMuettaulalCIlnimsuarxanFcoeuAndllaiatniocne, Inc. American President Lines Ltd. AAmmeerriiccaann TVeislecposheonCeorapnodrTateiloengraph Company Armco Steel Corporation AArtlmanotuirc aRnedfinCionmg pCaonmy pany JB.aTus.cBhaaknerd CLhoemmbicOalpCtiocmalpCanoympany Baxter Laboratories, Inc. BBaetyhulkehCemigarSst,eeIlncC. ompany BBroiesitnogl-MAyireprslaCneomCpoamnpyany BBuurdldinCgtoomnpIanndyustries, Inc. Burroughs Wellcome and Company CCaamlifpobrnelila SToeuxpasCoOmilpCanoyrporation The Carrier Foundation, Inc. CCaartesorpn,illPairriTe,raScctootrt aCnodmCpaonmypany CCehlaamnepsieonCoPrappoerratainond oFfibAremeCroicmapany CChhaasneceMVaonuhgahtttaAnirBcarnakft, Inc. TChheesaCpheeamkestrCaonrdpoCroartipoonraotfioVnirginia CChitrieyssleSrerCviocrepoCroamtiopnany CCloelvgiattee-CPoarlmpoorliavteioCn ompany Columbian Carbon Company CoonfsoNleidwatYedorEk,diIsnocn. Company CCoonnttiinneennttaall OCailnCCoommppaannyy, Inc. Corn Products Refining Company Corning Glass Works CCrroowusne-ZHeilnledrsbCacohmFpoaunnydation CCuurmtims iPnusbElinsghiinneg CCoommppaannyy DDeeetrroeitanEddiCsoonmpCaonmypany DDooudggleasMAainrucrfaafcttuCroinmgpCanoyrporation Dow Chemical Company ED.uIp.oDntu,pMonr.t IdreenNeeemours and Company EEaassttmOahnioKGodaaskCComompapnayny EElnedcticroicttSJtoorhangseonBaCttoerrpyorCaotmionpany Equitable Life Assurance Society of U.S. Esso Standard EEsthsoylRCesoeraprocrhataionnd Engineering FFaawirccehtitl-dDCeaarminegraPrainndtinIgnsCtroummpeanntyCompany FFeeddeerraall-MPaopgeurl-BBooawredrCBoemarpinagnsy,, IInncc.. FFeirdeesrtaotneedTDireepaarntdmeRnutbSbteorreCs,oImncp.any Food & Drug Research Laboratories, Inc. Ford Motor Company TGheneerGaalrrAetmCeroircpaonraTtiroannsportation Company GGeenneerraall ADynnilainmeicasnCdoFriplmoraCtioornporation GGeenneerraall EFoleocdtrsicCoCropmorpaatnioyn GGeenneerraall MMioltlso,rsInCco. rporation GGelonbeer-aUl nTiiorne, aInndcoRrpuobrbaetredCompany Goldman, Sachs and Company 1004 LIST OF DONORS TThhee BG.oFod. yGeaorodTriirceh aCnodmRpuanbyber Company Gulf Oil Corporation Gulf Research and Development Company HHaarznleitsocnhfeLgaebroCraotroprioersa, tiIonnc. Helm, Mr. Harold D. H. HHeerycduelnesNPewowpdoerrt CChoemmpiacnayl ,CIonrcp.oration HHiinnme, aCn., HM.,r.MJ.oDh.n H. THhofefmHaono-vLear RCoocmhpea, nIyncorporated GHeoop.eAN. aHtuorraml eGl aasnCdoCmopmanpyany HHuugmhbelseAOirilcraanftd CRoemfipnainngy Company IInndlaunsdtriSatleeMl eCdoicmapl aAnsysociation IInntteerrnnaattiioonnaall BHuasrivneesstserMCacohminpeasnyCorporation IntCeorrnpaotiroantiaolnMinerals and Chemicals IInntteerrnnaattiioonnaall TReelseispthaonncee CanodmpTaenleygraph IraCnoiarpnorOaitlioCnonsortium Johns-Manville Corporation JS.ohCn.sJoonhnansodnJ&ohSnosno,nInc. Jones & Laughlin Steel Corporation MMiilnees SLaafbeotyraAtoprpielisa,nIcnecs. Company Monsanto Chemical Company NNaattiioonnaall DBaisicruyitPrCoodmucptasnCyorporation NaSteiorvniacel,InDsetpitaurttems eonft HoefaHlthe,alPthu,blEicduHcaeatilothn NaatniodnWaleLlfeaarde Company NNeewwpOorrtleNaneswsPuSbhliipcbSueilrdviinceg, &InDc.rydock Co. NNeeww YYoorrkk LSitfaeteInNsuartuanracel GCaosmCpaonrpyoration TNhewe NYeowrkYSotartkeTSiomcieesty of Industrial Medicine The News, New York North American Aviation, Inc. Norton Company OOhliino MOialthCieosmopnanCyhemical Corporation OOwtisenEs-lCevoartnoirngCompany Owens-Illinois Glass Company PPaanra-AmmouernitcaPnicWtuorersldCAoirrpwoaryast,ioInnc. TPehnensPyelovpalneisaNRaatuilrraoladGas Company PPeitptssbi-uCroglha CStoemelpCanoympany Procter and Gamble Company Provident Life & Accident Insurance Co. KKaeinsnerecIontdt uCsotrpipeserCCoorprpooraratitoionn KKiomppbeerrslyC-ColmarpkanCyo,rIpnocroartpioonrated LLeagSgaell,eRS.teTe.l, CMo.mD.pany LLeevTeoruBrnreoas.uC-Womesptianngyhouse Company LLiibfeerEtyxteMnusitounalEIxnasmurinanercse Company Eli Lilly and .Company Thomas J. Lipton, Incorporated The Magnavox Company The Mead Corporation MMeeidgisc,aJl .SWoc.i,etMy .oDf.the State of New York Metropolitan Life Insurance Company RRaadytihoeoCnorCpoomraptiaonny of America Republic Steel Corporation RReeyvnloonldsFoMunetdaalstioCno,mIpnacnoyrporated RR.icJh.fiReledynOolidl sCToropboarcactoioCnompany John A. Roeblings &Sons Corporation Joseph E. Seagram & Sons, Inc. SSihmelplleOxilWCiroemapnadnyCable Company ASi.nOcla. iSrmRitehfinCinorgpCoroamtipoanny Socony Mobil Oil Company SSpoenrorcyo GPyrroodsuccotpseCCoommppaannyy SSttaannddaarrdd OOiill CCoommppaannyy ((CInadliifaonrna)ia) LIST OF DONORS 1005 StaannddaradffiOliaitlesCompany (New Jersey) Standard Oil Company (Ohio) Standard Railway Equipment Company StaFnoduanrdda-Vtiaocnuum Oil Company Stauffer Corporation Studebaker Packard Corporation SSuugnaOr iBleCetomPrpoadnuycts Company SSuwnifsttraanndd CCoomrppoarnaytion Sylvania Electric Products, Inc. TTeanmnpeassxe,eInCcoorrppoorraattieodn Texas Company TTiedxeaws aItnesrtrOumileCnotsm, pInacn.y TTrhaensMWichoareldl TAoirdwdayEsstate The Travelers UUnniioonn OCailrbCiodme pCaonrypoorfaCtiaolnifornia United Artists Corporation United States Atomic Energy Commission UUnniitteedd SSttaatteess SRtueeblbCerorCpoomraptaionny United Steel Workers of America Universal Oil Products Company Upjohn Company VAW--International Executive Board WWaeisrhtionngtSotneeSlteCeol mCpoarnpyoration Western Electric Company, Inc. WWeilsstoinng, hMour.seCEhalercletrsicE.Corporation Wilson &Toomer Fertilizer Company WWoiroedmarodldRCeosemaprcahnyCorporation Wm. Wrigley, Jr. Company Union Bag-Camp Paper Company Zenith Radio Corporation THIRTEENTH CONGRESS ON July 25-29, i960 % Copyright 1961 by the U. S. Executive Committee of the Thirteenth International Congress on Occupational Health ALL RIGHTS RESERVED Library of Congress Catalog Card Number: 58-32683 Public Health GIFT DESIGNED BY HARVEY SATENSTE1N MANUFACTURED IN THE UNITED STATES OF AMERICA BY BOOK CRAFTSMEN ASSOCIATES, INC., NEW YORK Ai 3 /X<?u(oAvlio Hea~IHsu Li brcLrcj EXECUTIVE COMMITTEE Chairman.........................L . W ade, M .D . Vice-Chairmen.........................L. G reenburg, M.D. S. E. M iller , M.D. Secretary-General.........................R. E. E ckardt, M.D. Treasurer.........................H. E. T ebrock, M.D. Executive Secretary.........................J. W . M uckxll E. R. A ston, D.D.S. C. U. D ern eh l, M .D . T . E ly, M.D. B. S. Fox J. L auer, M .D. H. L. M agnuson, M.D. H. B. N a c h t ig a l l , M.D. N . N elson, Ph.D. M . N . N ewquist, M .D . L. T. R obertson, M.D. I. R. T abersh aw , M.D. S. P. W agner, R.N. 10 REPORTS OF ORGANIZING COMMITTEES In addition, many others visited points of interest to them either before or after the Congress. When the debris had been cleared away and the hubbub had subsided by Saturday, July 30, the paid registrations figures for the Congress were as shown in the following tabulation. NUM BER OF REGISTRANTS -- BY COUNTRIES Country Total Afghanistan ....................... ................ 1 Algeria ............................... ................ 1 Argentina ........................ ................ 19 Australia .......................... ................ 3 Austria ............................... ................ 8 Bahrein ............................ ................ 1 Belgium ............................ ................ 2 Bolivia ............................... ................ 1 Brazil ................................. ................ 5 British Guiana ................ ................ 2 Canada ............................... ................ 54 C h ile................................. ................ 4 Colombia ........................ ................ 9 C u b a................................. ................ 5 Czechoslovakia .............. ................ 1 Denmark ........................ ................ 4 Finland .......................... ................ 62 France ............................. ................ 39 Germany ........................ ................ 36 Greece ............................ ................ 1 In d ia ................................. ................ 5 Indonesia ........................ ................ 1 Iran ................................. ................ Ireland .......... 21 Israel ............................... .................. 2 Italy ................................. ................ 21 Country Total Japan ....................................... .......... 20 Luxembourg .......................... .......... 3 Mexico ..................................... .......... 6 Morocco .................................. .......... 1 Netherlands............................ .......... 16 Netherlands-Antilles ............ .......... 2 Northern Rhodesia .............. .......... 1 Norway .................................. .......... 13 Pakistan .................................. .......... 1 Peru ........................................ .......... 4 Philippines ............................ .......... 5 Portugal .................................. .......... 5 Romania ................................ .......... 1 Spain ...................................... .......... 5 Sweden ..................................... .......... 29 Switzerland ............................ .......... 6 Thailand ................................ .......... 1 Trinidad ................................ .......... 2 Union of South A frica........ .......... 9 United Kingdom .................. .......... 94 United States ........................ .......... 1040 Uruguay ................................ .......... 2 U.S.S.R....................................... .......... 1 Venezuela .............................. .......... 7 Yugoslavia .............................. .......... 4 Total .............................. ..........1568 One hundred and ten people paid and registered but were unable, for one reason or another, to attend. Thus the total actually present, exclusive of wives or guests, was 1458. It is the impression of the Organizing Committee that the Congress was an overwhelming success. Certainly the number and quality of the scientific papers delivered was outstanding. Dr. Irving Tabershaw and his whole Program Committee deserve a special note of thanks for the hard work entailed in bringing such an excellent program to the Congress. It is the hope of the Organizing Committee that all those who attended, especially those from foreign lands, not only learned much from their attendance at the Congress but found our land and our people friendly and hospitable. We hope that new friendships were made, new understand ings reached, and that the memories of the Thirteenth International Congress on Occupa tional Health will linger long. Speaking for all members of the Organizing Committee, it was a pleasure and privilege for us to plan the Congress and welcome all who attended. }f?t. in m. v th 1i th th 1 po he ! i ctoii I i8 at pr ac 1; w< ( I; oPf' > 1% scf Wi I bi >; <ioh th be ar in th b( I M Ir Y J< KIVILUOTO 311 masl ionf tAhpepbeunfdfiexr d1e.scNriobremdaillnyAfpoprebnldoioxd1,spaencdimceonnstinthuee foifnatlhrwicaeshasinfgormuursint ebespepceirmfoernms.ed four times, instead APPENDIX 3-- COPROPORPHYRIN ESTIMATION tubTeo a5ddm0l.2fremslhly3 pveoridecdenturhinyedroingena psteorpopxeidreedsotelust gtieonnt,ly1, rmelleagsleacpiraelssaucreet,icanadcidplaacned in3 amlligehthtperro.oSfhbaokxe ovivoelrentiglhigt.htO, basnedrvegrtahdee rethde flsupoerceismceennce0-u+nd+e+r +ultrbay degree of fluorescence. APPENDIX 4-- HEMOGLOBIN DETERMINATION wiTthake0.40.0p5emr lcbenlotoda,mamndonmiuamke huypdrtoox9idem. isMveoalusumree a(EbEsoLrp4ti0o4n), oannda ccoonlovreirmt etthere, ruesaindginga tsotanhdeamrodglfoilbtienr ppearrceedntcaagleibrtaotiothnegrnaepahr.est even number from a pre APPENDIX 5-- PUNCTATE BASOPHIL COUNTS thiMckankeessa, ftixhinforblaoboodutsmoneaermoinnuatesliindemoefth0y.l8-1a.l0comhoml, a(1llogwmteothdyrleyneanbdluset,a6ingfsoord3iu0msebciocnadrsboinnatSeelilnars10s0taminl daesioeanigzeredenwactoelro)r.. Wash in tap water until the slide is eyeUpsiiencge saet dtoarak 6-gmromunsdquacroen,dceonusnert thaned,puannctaEtehrcleicllhs ipnuntcetnatecocnesllescaurtieveclafsiseilfdise.d (aAs lltahrogue,gmh eidniucmo,usnmtianlgl,,vtehrye cfienlelu, loarr psotlryucchturorem,e,thaicscodridfifnegretnotiathtieonsizies offotrhefuirntthrear rtoeftearlenccoeunotn iasngiinvdeinv.)iduCalolsceasteh,eanedyenpoiercmealtloy oanl2y-mthme sbqoutharec,ouanntds cfiovuenttimthese oRn.Bd.Cif.feirnentthpisartssquoafret.heRespliedaet, Rto.Bg.Civ.e caoupnut nocftatfeivecosumnat llofon5e0s. laCrgaelcufliaetleds paunndctaatne per 1000 R.B.C. NONOCCUPATIONAL ASBESTOSIS R aimo Kiviluoto Roentgen Department of the Central Hospital of Northern Karelia Introduction InPtlheueraaldvreanaccteidoncaissesveoryf tohfitsenpnoebusmerovceodniinosiassbpelsetousriasl. fciobrrroesliastiohnas bbeteweneenalmploesutraallwcahyasngfeosunadn,d atnhde saevcelreiatyr ionfvtehsetigpautolmrso. nOabryserfvibartoiosinsshoans tbheeenococbusrerrevnecde boyf psleevuerraall coaflcpifliecuartiaoln cinalcaisfbiceasttioosnis hasavea arlosoenbtegeennomloagdiec. Rsigepnorotsr cboymtphleicaGtieornmaonf aasubthesotrossis(1)h.avIne aesdpdeictiioalnly tobeaednvamnacedde cwahseicshofplaesubreasltosciasl,cisfpiceactiiaolncahsaess hbaeveen bteheen cphrieesfenfitneddining b(2e)e.nEoxbcseeprtveidn aamsboensgtoswiso,rkpelresureaxlpocsaeldciftiocattailocnahnads mailcsoa a(3sb,4e)stoosr (t5o).various dusts including a short exposure to onThocecudpiaagtinoonsaisl oexf pponseuurme otcoondiuossti.s Oisnplyrimvearryilyfewbasreed pmoaryts boef pfnoeuunmdoicnontihoeseslitweirtahtouuret o(c6c,u7p,8a)t.ioInnal Nexoprtohseurrne bKeaerneliaat,traFcitneldanbdy, tdhuerhiniggh fienwcidpeanscte yoefacrsaseisntoefrepslteuhraasl croaelcnitfgiceantoiolongsihcowpiicntgurae,ravtehreyr csiumriiolaurs atondthchaat raocbtseerrivsteidc ianmponnegumthoecorneisoidseesn.tsThoef caasceesrhtaaivne abreeean, manadinliyn fothuensde pcaleseusranlodipsreeavseioucsouhldistboeryeloifcitaedde.qTuahtee opcuclumpoantiaornys oorf othfe tphaetiepnattsiesnhtsowheaddnonounciflionrimcailty,syamnpdtotmhes moafinpnpeaurt mreovceoanleidositsh.aAt thsetuydwy eoref gthroeuapreedalroduinstdribtwutoioannthoof pchaysel-s leixtet-earsnbaelstofsactmorinesso.uAghstb.estEovsenconfrsotimtutead stohleelycomromenotn gbeeneonlocgoincsipdoeriendt othfevimewos,t apsrboebstaobsleduestitolionghya.lation had tubPelrecuurlaolsisc,alocrifiecmatipoynemraesuusltuianlgly forcocmurs huenmiloattheorarallxy, manadrkiesd siptuleauteradl otnhictkheenivnisgcearanld pdleisuprala.ceInmemntostofcatshees isnutlrtainthgorfraocmic dourgstanisnhisalaotbiosenrvuesdu.aTllyheocccaulcrsifibcialtaitoenrarlley aadnvdaniscemdosctasoefstencalsciituumateddeopnositthse apraerieftoaul npdleuinra. thIne lTahteeraclalpcaiurtms odfeptohseitschteaskte, bvaasraiolluys afnodrmms--edlaiarsgteinaclolyn. fluent plaques, bizarre figures, or roundish spots. The Roentgenologic and Clinical Picture of Cases Observed in Northern Karelia bilIantertahlely aidnvatnhceedcecnatsreasl pcaalrctisumof dtheepodsiitaspharraegmfo;unodn cahnedstown atlhlse, mesepdeciaiasltliynaalnstuerrfoalcaetse.raIlnlythbeutinaclsipoiednotrscaalslyes; tlahteercaallccihuemst dwepalols,itmtoarkeesofptleanceoneiththeer loenft,thoer ainntetrhoe ocenntrtahle parirgtshto. f Ptheericdairadpiharlagcmal,ciafpicpaatiroenntlyis msoormeetoifmteens preTsheent.calcium deposits are located on the parietal pdelepuorsai.tsIwneare soebriseesrvoefd.15T0hecapseasrinetoalinlotecraltoiobnarhcaaslcbieuemn dtieomnso,nasntrdatietdhabsyalsdoiabgeneonstnicotepdneinumsoomtheoraauxtopesxieadmainnad spuarrgieictaall lcoacseast.ioUn soinfgsoalittaarnygepnltaiqaul ersoemnatgyenbeboebamse,rvtehde, tchheesset wpalallquoerstohwaavridngthethdeiiarphbraasgems .toInwaarddvanthceedicnanseers the lack of soft tissue mass between the calcium deposit MEDICAL PRACTICES aapndpariennnte,ranchdesdtiawgnaollstdicuael ptoneuthmeotphaorrieatxalexloamcaitnioantioins pasublmestoonsarmyinfeisb.rosis among residents around the two is Tsehldeommanjoeeridtyed.of cases of pleural calcification de attSroibmuetiningvetshtiegactoalrcsifhicaavteiopnoitnoteidnhoaulat titohne ddifafmicaugltey ionf sscerriibesedofa1b5o0vecasheasvtehebeoerndincalrinyiccahlelyst sroymenpttgoemnleesxsa. mIninaa voibeswervoefditsinpatrhieetalul nlgocaotrionth,efevwi,sciefraalnyp,lcehuarnage(2s,5b)e.inIgt ftiibornosbisy, Pc-oArraenspdonladtienrgal tporotjheectiaonntseprreivmeaalreyd oprulpmriomnaarryy slueenmgs apnodssivbilsecetrhalatptlheueraasbinestoreslaftiiboenrs tmoovthee wpiathrietthael scteangte. Eovfenputlhmeonmaaryin apsabretstoosfisthienseocnalysesabhoaudt n1o4 spuebr ponlelyu,ra,asthpursevicoauussliyngprceaspeinlltaerdy bhyemtohrerhaaguetshoor.n Tthhies jective respiratory symptoms. The series mentioned above has been selected solely hlaegmenoorruhsagpelacqouaeguwlahteicshansldowolrygacnaizlceisfi,esf.orTmhinisg tahecoorly atoccootrhdeinr gfatcotorths.eTrhoeenctognencendtiraagtnioonsisofwtihtheocuatserseaferroeunncde cinohualdlateixopnlaoinf stmheallcoquurasentoitfietsheofprfoibcreosussremsuinlteirnagl dfruosmt. ctwomo masubneesstohsasmainseysetinbeKenuuthsjearovnilyanwdayittso nceoingfhirbmoritnhge seeTmhse toclinbiecaslligsihgtn,iftihceancmeajoofritthye opflecuasreasl schaolcwifiincgatinoon roouetsnitdgeenthidsiaagrneoasihsa. dTphreevimouasjloyritlyiveodf th2e5rec.aAsecscolrivdiinngg colninitchaisl proesinptiraatroeryneesdyemdp. toms. Further investigations tfoicutlhtestoe fcarcetdsi,t.anIny voethryerfeewtiolcoagseys wa opurledviboeusveorcycudpiaf pleFuroraml craolceinfitcgaetnioonlogisicofpsooimnte soifgnvifiiecwan, cet.hiTs heenrdoeemnitc wtiohnicahl leexnpdossusrleightto suaspbpeostrotstodutshte hraosenbtgeeenn doibasgenrovseids., gdiefnficduilatg. nEosairslyis pinleutyraplicaclhacansgeesseaosny bthuet inansteormoelactearsaesl Tmheethoddiasg. nIonsitshehasspuastuymet onfo2t0bceaesnesconnofiarsmbeedstobsybootdhieesr cphlaeqstuewsalml amyaycasuimseuldaitfeficinulftiyltriantioinnste, rapnrdetalatriogen coaflcipfiueld wameroeunftouonfd,anatnhdophasyblelistteosasfbiebsetrosinwaosnefoucnasde. inSmtahlel mvooltnaagrey cthecanhgneiqsubey hcaidninhgeirnefbiyltrabtieoness.pTechieallhyighreckoilmo- lfuronmg othfeavnicainuittoypsoifedthecaassebeasntods imninteh.e lung of a cow masebnesdteods.mIninecsheisnt Nrooernthtgeernn eKxaarmeliinaaatinodnsofofOwutoorkkuermspouf j Discussion Cbeopppearidmitnoesthloecatfeadct inthtahte seavmene aerexatenasttivenetiobnilamteuraslt fafi pleural calcification does not have to be a sign of aroTuhned ttohteal twnuomabsebrestoofs cmasiensesofampoleuunrtasl tocalocvifeicra8ti0o0n, sdeuvsetreexppuolsmuroen.ary changes resulting from occupational acsasepsrewviaosufsolyunrdepionrtaedmabsys tshuerveayutohfora.bTouhtis10n,u0m00baedruoltf REFERENCES ipnahtiaobniatalnetsxpaonsdurme atyo inascbluesdteoscadsuesst.wiItnh pthreevihoiustsoroyccouf 1. JKaocombp,liGka.,tioanndenBodhelrig, LHu.n:geDniaesbresnttogseen.olFogoirstcschhern. pthitealmoafinNopratrhteronf cKaasereslieaxathmeinleadckaotfthoeccuCpeanttiroanlalHeoxs posure has, however, been apparent. Some of the 2. RMunltlgere,nsHtr..:, 83b:5e1r5s,c1h9w55e.re Formen der Asbestose. Die Staublungenerkrankungen, Band 3, Wissen pcoautilednthsahvaevehanpoptehnaedd;antyheidseaamheowcasthese hdauvset ipnrheasluamtioend sVcehralfatg!., FDoarrsmchstuandgt,sb1e9r5ic8h. te 66. Dietrich Steinkopff 3. Siegal, W.; Smith, A. R.; and Greenburg, L.: Study IthnaNt tohrethdeurnstKriasrienlgiaotnhethreoardosad(shimghigwhatysb)e droespnoontshibalvee. o19f43ta.lc miners and millers. Indust. Bull., 22:434, pcoauvresme,einmt.pWossiitbhloeuttomdeinceidraelowghicetheexramthiensaeticoanlscifiitcaitsi,onosf 4. eSxmpiothsu, rAe . tRo.:cePrlteauinralducasltcs.ificAamtio. nJ.resRuolteinntggefnroolm., adruestreosruigltiinnagtinfrgomfroimnhathlaetiaosnbeosftoasntmhionpehsylolritef-raosmbesstuors 5. 6F7e:h3r7e5,,W19.5:2. ber doppelseitige Pleuraverkalkungen faascbeesdtoesp,owsihtsicohfisotahevrerfyibcrooumsmdounstsm, insuecrhal aisn tNreomrtohlietren- iRnfonltggeensbter.r,uf8l.5ic:1h6e,r 19S5t6a.ubeinwirkungen. Fortschr. aKbalree.lia. The first alternative seems to be more prob In occupational pneumoconiosis some authors have 6. Emiasnen, bLu.dT, .M; .H; aWrriasn, tWa,. RB..; Ca.n; dDWusotlafn, ,BC. .S;.:SNteoand- occupational berylliosis. Am. ]. Indust. Hyg., cbaelslieddesatthteentpiroonmitonenthteapapbeseanracneceofopf utlhmeopnlaeruyraflibcraolsciis 7. 3G1o:2y8al2,,R1.94K9..: Pneumoconiosis in the non-industrial population of Rajasthan. J. Indian Med. Ass., hfiacsatiboenen(2o,5b)s;ervoend thbeetwoethener thheansde,vearitcyleoarf pcuorlmreolantaioryn 8. 3K0i:v7i9lu, o1t9o5,8.R.: Pleural calcification as a roent faisbbreosstiossaisnidt pisleauprpaalrceanlct ifthicaattioexnte(9n)s.ivIne cnaclnciofciccautpioantiomnaayl gpehnyolllioteg-iacsbsiegsntosoifs.noAnc-toaccruapdaiotilo.,nsaul pepnld.em19i4c, a1n9t6h0o.- omcocnuarrywiftihbrooustis.anIty sereomenstgpeonsosilbolgeictahllayt edveetnecvtaebryle smpualll 9. tBoosehlidge,rHL.u; nJgaecno.b,GGe.o;rganTdhiMemuleleVr,eHrla.:g,DSietuAttsgbaerst, atimonosu.nts of asbestos fibers may cause pleural calcifica 10. V19o6r0w. ald, A. J.; Durkan, T. M.; and Pratt, P. C.: InAanntihmoaplhytellsittse bisritmtloeremsintieffratlhafinbesresrpheanvteinneotascbaeustsoesd. EHxypge.,ri3m:1e,n1ta9l51.studies of asbestosis. Arch. Indust. 11. Noro, L.: On the histology of asbestosis. Acta pinulwmoornkaerrys feixbproossiesd(1to0),abntuhtopfihbyrollsiitse-haassbebsetoesn doubssterv(1e1d, 12). Further studies are needed to reveal the part 12. PWaetgheolli,ues,t Cm.i:crCohbainogl.eSscianndth.,e23lu:5n3g,s1i9n461.26 cases of asbestosis observed in Finland. Acta radiol., 28:139, possibly played by asbestos as an etiologic factor in 1947. 326 MEDICAL PRACTICES A REVIEW OF RECENT DEVELOPMENTS IN OCCUPATIONAL PULMONARY DISEASES OTHER THAN SILICOSIS Leo Noro, M.D. Finland tioAntalthHeeaTlwthelfhtehldInitnernHaetlisoinnakli Cthornegeresyseaorsn aOgocc, utphae Fsurebnjeccht mPreonfteisosnoerdMinarcthheantdit.lep,reaselanrtgeed aandrevcioemwporefhtehne sTivhee bOibrgliaongizrainpghyCobmeimngittaeettahcahsedat ttohihsistimpreesaesnkteadtiomne. stoevperraelseynetaras. rIetvimewustofatthoencseambee ssauibdjetchtaftrothme tchoemlpaislt ienagsy otfassku.chMoarebitbhlaiongreavpehricberfeovriee,wrehsaesarcnhot wboerekn haans bperoenblefmocuhseads obneeonccduispcautsiosendal aptulnmatoionnarayl dainsdeasienst.eTrnhae atigoonailn mMeeiltainng. sF, rtohme ltahset ltiitmereatbueriengwhoinclhy htwaso bmeeonnthast mreycednitspyoeasarsl,dIeahlaivneg fwoiutnhdthailsmsousbtje3c1t6, aarntdiclyeest fIrocmannthoet hliasvheedhaind tahcceesws otrolda.llI thshealalrtficolleloswf,rowmiththissomfieeldexpcuebp tioTnsh,erMe airschraenasdo'sn ctloasssitfaitceatiaotn.the onset that the con sbteacnotmiendmusotrriealiaznindg misorceauspionlgluttehde. aiGr rewaet bmreaasstehse otof pcoeuonptlrei,ese,veanrethechpaenogpilnegs otfhethire sborecaatlhleindglesasi-rdetvherlooupgehd Ithaemir mheorveemtheinntkifnrogmspaegcriifcicualltluyraalbotoutintdhuesthriuagleceinndteurss. atrniadliCzahtiinoan. Bpruotcemssanr'sigbhrteantohwingtaokrginagns,plaancde eisnpeIcniadlliya hfliusenlucnesgso, ndlyo innotthceomweoirnkincgonetancvtirwonitmhenhta.zaTrdhoeusmoinst --coims mraopnidployllutrtiaunmt pohfionugr ablrleaotvheirngthaeir--wotorbldaccwoitshmothkee rdioscintogrssttaankedatrodwoafrnlimvinangk, inind ospf iittes doafngtheer. Tefhfoertasuwtoe mpoolbluiltee itnhdeusatirryoifs pthreodturacfifnicg rcoaardssi.nWairthapitdhetegmropwointgo ppoowpuelratiaonnd chenetaetrisn,g,anmd otrheeirpoinllcurteaanstesd eunseteor f tfhueel afiorr. Bhaavceternioast,dvisiraupspeesa, rsepdonegitehse,r.anTdhuost,htehresemnavlilroonrgmaennistmosf Wmahni,lewtihthe rgefreeraetnceenetmo ylunogfs,thies clhuannggsi,ngtubcoernctiunlouosiuss,lyis. gnerawduiamllpyodrtiasnacpepetaorinthge, naeiwr idmispeausreitsieasr.e Carhirsoinngic, gbivroinng mchuitcihs, amstohrme a,imempoprhtyasnetmdai,seaansdeslutnhgancantcuebreracrueloalsriesadiyn lciovuinngtrisetsanwdaitrhd.highly developed industry and a high enMviraonnmhimenstelaflsaondretqhueircehaantgteinngtioonf.hAisllreeragcietisonarteo othnee pinrogbloermga,nfisomr sextahmropuleg.hTthhee draenspgierratoofryallaenrgdendsigaefsfteicvte moregdaincsineasn,dfotohdes, sckoisnmiesticcso, netticn.,uoaureslycominmcroenasianllge;rgneenws. Abrleleartghiicngreaocrtgioannss aarnedimthpeoirrtaonbtvwiohuesn cwonenceocntisoidnerwtihthe tdhiseeaasiers iomfptuhreitileusn.gsMoacncyurofontlhye acfhterronaiclooncgcuepxaptoiosunrael otifmeth. eWsee dairseeagserasduaamlloyn,ghotwhoesveer,ococbusepravtiiongnalthegrsoiugpnss which have been exposed for some length of time. is Oaulrreakdnyowflaeidrglye ocfommapnleytef:actIorsaminfltuheinnckiinngg thoenllyungosf ainsbjuersiteoss,is;sutchhoseasmcahnlyor choerminciatlrsoucsaufsuinmgesa; cuatned lutnhge doiusreaksensowclaeudsgeed isbystibllacvteerryia,ressptroincgteeds,, aonrdvitrhueseisn.teOrpftreen ttahtiisoniss tirnuemoafnyallienrdgiivcidduisaelasceasseasnadrechdrioffnicicultbrtooncmhaikties:, alunndg escpaencciearl,lyemofphthyesermoale, oafndnofnipbrroosfeisssoionnatlhaendwhporloe, hfeasvseio, nwalithensvpiercoinaml eanptpsreicniatitohneirtooGccruerartenBcer.itaYine'ts ewxe pceolslaelnt ovfitatlhestarteisltaitciso,nsimhipporbtaentwt eeevnideonccceupaattioonur adnisd ceArtaftienr ptuhlims ogneanryeradlisesauservs,eys,ucnhowas clhertonuisc bstruodnychitthise. dcoetnanilesc.tioSnin, cIeshsaillilcobseigsinwwillithbeasbdeisstcoussiss.ed in another Asbestosis asbTehsteosmisajiosrcpoanrttaionfeodurinprtehseenetxkcneollwenlet dGgeercmonacnerbnoinogk LthuantgeanppbeyareBdohsloigm-eJacmobo-nMthisillearg.o,ThDisie bAosobkesctoosnetaidnesr, pinracatdicdailtliyon thtoe 7e0n0tiroef wthoerilrd olwitneractausrees, irnefetrheinscesfietlod a(sboomuet 6th5e0 preaftehroegnecnese)s.isT, hcelirneic,ispnroogthnionsgis,baasnidcalplyrevneenw otibotnainoefdthaibsoduitsetahsee. fFreuqrutehnecryinofforcmlinaitcioanl siysm, hpotowmesvears, wfreolml atshreoaenuttgheonros'locgaircefaunldexbarmoninchatoigornapohnicthoebisremrvaatteiorinasl olufn7g00cacnacseers.isThsteillresltaattiiostnicsahlilpy binetdweteeernmiansebdes.toIsnissapnitde othfetihrios,wn"assbpeesctiofiscactaionncetro" iet.xists, and the authors give affDecotesas,asfboerstoexsamdupslet, hbaevryellisuimm?ilaTr hinsonisocacuppraotbiolenmal nthoantochcaus pbaetieonnaelxpopsleedurathl rocuaglchiftihcaetioobnsercvasaetison(sso-ocfal1le2d6 lnaetiigohnbolirvhionogdacraosuens)d thtwaot hoapdenbeaesnbefsotousndquinarrtihees,ppoupbu lsitsuhdeyd, tbhye tdheetaFilisnonfiswhhDicrh. Kthievialuuothtoo.rAwcicllorpdriensgenttohtihmis stieolfn actastehsisweCreonfgoruenssd, imnotrhee tmhainnut8e00x-pralyeuirnavlesctailgcaiftiicoan oanf yfaromcceursp,atwioonraklmeenx,poasnudret.heCiarlcwifiivceast,iownhowansevuesruhalaldy loocccautpedatiionnaplaraisebteasltopsilse.urIan, amsoistt iisnsatlasnocemsoistt oocftceunrreind' basiltaintearlallcyalcoifnicathtieoninwnaesr cahlseost owftaelnl. oBbassearlveadn,d ampeudli mcaolcniafircyatfioibnrowsiass bneoitnicgedfotuondapopnelayr oslnowalyf.ewThceasseesr.oTenhtegiceanlolsoygmicpatlolymns.otiTcheaebsele ochbasnergveastigoanvse imnsaikgenifiitcaenvt icdleinnt ttihoant omfetahseureensvmirounstmbeentstaskuernrotuonpdrienvgenthtethfaectaoirriepsoallnud aasrbeemstoostivqautiaornriefso.rTsihmeilraersuinltvsesotifgaDtiro.nKs iivnilouothtoe'rs cwoournk tries to certify these observations. NORO 327 cOotnhieorsifsi"brcoatiucseludnbgydsisileiacsaetsesa,nmd i"xbedenoigrnnponne-usimlicoa cdaursbtosru(Gndlausms ,wocoeml, esnetr,icFiteu,llesirl'lsimeaanrtihte,, cthalicn,a aannthdrabcoalll, cmlaicyas,, Tghroapmhaiste,(bagsyicp)susmla,g, keatco.l)in, limestone, marble, talIcossihsalalndpasgsratphhisitegrluonugp, wwihtihchaarberiesftillmoebnjteioctns ooff cdoonutbinteudoluys, trheesedarucshts. Wofitthhisgrgeraotuepnohauvgeh tehxepior saufrfee,ctuinn wthiethocicmurprreonvceedofhyfigbireonseis. tHheosweevteyrp,eist iosf evpiudlemntontahrayt changes will become more and more rare. Pneumopathies due to toxic chemicals and metals deGsmasoedsu, r,F uhmydersocaanrdbonVsa,pooirlss, (kCerl,osNenOe,a,etSc.0) 2, borans, cadMmetiuamls, c(hArloumm,incioubma,lt,afnlutiomr,ong,oldb,ariiruomn,, mbaenrgyallniuesme,, ntiitcakneilu,mo,smvaiunmad,iupmla,tiwnuomlfr,amse,lezniricuomn,iusmu,lfeutrc,.)tungsten, ingThteheamlounugnst oifs tocxoincticnhueomuisclayls garnodwimnge.talVs ainnaflduieunmc, cehsproecmia,llayndinbeSrwyleldiuemn ahnadve inbeeonursuhbjoescttscoouf nrtersye,artchhe, Ucr.eSa.sAin. gT. hIet iims pnoercteasnscaery,ofhvowaneavdeiru,mtoisbeesapreciinallymiinnd othilatcowmitihngthferoemxpvaanrdiionugs upsaertosf oofilthheeatwinogrl,dthceonctrauidnes vacaincadsiuulmfurincovmerpyoduinfdfesreinnt atmheouansths.esThise arolsloe otof thbee rweomueldmbreerfeedr.yoFuortoathdeetpariolecdeedsitnugdsy ofofthbeercyolnlifuemre,nceI Hheeladltha)t; tahecomMp.Ir.eTh.enisnive19li5s8t o(Af .Mref.Aer.enAcerscho. nInbdeurystl. liniugms. WisecionntEaiunreodpei,ntoampyubklnicoawtlieodngeo,ndothnesoet hparovceetehde bthige Upr.oS.bAle.ms with beryllium which seem to exist in allIfthies inmewpocsshiebmlei,cainls twhiitshsihrorirttanptreesfefnectattoionn,thteo lnuanmgse. Wteme pitnindgusttoriaelvaplhuyasteicitahnes ahftaevreeffsepcetscioalf adcifuftiecuilrtireistanatts wtoiththerelfuenregnsce(nittorouetsiofluomgiecs,diCffle,reSnOtiza,l etdci.a)g, neosspteiccsialilny chronic bronchitis and emphysema. pPnneeuummoompaytchoiseessdu(Ae cttoinoormgyacnoiscis,duasstpse,raglillelorsgise,nscoacncdi ddyioeisd,omfeyactohseirss,,cofrlkou(sr,ubgerroasiins,), cgoutmtona(cbaycsisai,noshias)i,r,druhgasy, (bfoasrims),er'slinleunn,g),mohnisitloiapsliass,monsoics,ardjuiotsei,s, lesapthoerortri(cchanonsias-, swuogoadrs,ceatnce.) (bagassosis),- tobacco (tabaccosis), tropical attTehnteioangrdiucruilntugrathl eploapstulfaetwionyeahrassinretcheeiveindveisntcirgeaatsioedn olufntgh"e arenldatiootnhsehrippublemtwoneeanrywdoirskeaasnesd fhoeuanltdh.in"Faagrmriceur'ls tinuvreesthigaavteionpsr.oUvendforstuurnpartiesilnyg, lsyo fcaormthmeroenhauvpeonnotcbloeseenr pwohwereers tthoeinavgersitciugalttuerathl espeopcuolnadtiitoinonswionrktsheuncdoeurntrtihees wedogrest ahbyoguietntihcecopnudlmitioonnas.ryWdeisheaavseesnooft tehneouwgohrkkenroswiln the old Asian rice mills, for example. unTclheear,effaencdt mweechaarneismalsoof imn oast doirfgfiacnuilct dfiuesltds, iws hsetirlel bacteriology and allergology will be of much help in --sevaecruatle,cassuebsa. cWuthe,atchfaroctnoircs; epfrfoetcetinins,dailfcfaelroeindts,ciornridtiattiionngs imncelcuhdaendic--afarectoqrsu,esttoioxnics, tahlaletrgairce, sbtailcltewriaa,ititnhge tosilibcae wanisthwebryedss.inIonsisaidsdsittiiolln,cofnotrradeixcatomryplei,n tdhieffeerexnptercieonucne torfieEs.ngTlhanedinmtearkeestionnge rethsienakrchthraetsuthltiss odfisDears.eShcahsillninogt ymeyt dowisnapcpoeuanretrdy.as has been contemporary thought in aInncfheycltoiostuosmaonsids, paanrtharsaitxa,ibpilnheaurzmioosipsa, tbhruiecsell(oAsmis,ebhiyadsias-, etittco.)sis, leptospirosis, ornithosis, tuberculosis, tularaemia, difWficiuthltiethseindiseetaioselosgoicf tdhiiasgngorostuicps:thwerheenareiscothnetininufoeucs qtiuoensttioonbeiscovnesryideirmedpodrutaentt,o fwoorrkexaanmdplwe,hewnitnhot?tuTbehre caunldospisn.eOumf coocuornsieo,sethseisreulnatdieornschoinpstbaenttwseteundyt.uberculosis cLhuronmg actaens,ceirsodpuroeptyol oaclccuophaotliomn anu(Afarcsteunri,nga,sbneisctkoesl,, radTiohaectSivecerestuabrystaGnecnese,raeltco.)f our Congress, Dr. Eckardt, hreanncdeleosf thcaencroerleinofhwisobrkoionkg Icnodnudsittrioianls Cinarctihneogoecnceusirs msuospstecvtaerdietdhlyat ainndinwdiuthstrgyoomdacnryitioctishmer. sYuebtstiatnicsestoalbsoe hfiaevlde, ahocwaenvceerr,ogisensetitlilc veefrfyectl.imOituerd,kannodwleadltgheouignh tehxis pineripmraecntitcael cnaencceessrarryesefaacrctsh. Ihtasisghonoepefdar,thwate tshtiell wlaecllkewnidllowmeodrecatnhcaenr obregfoanreizactoionncsernandthermesseealvrcehs winistthitutthees ocTcuhpeatiroensualltsasfpreocmts itnhethienveetsiotilgoagtyioonf bcyancUe.rS.. Public Hmeinaeltrhs aSreerviecxepeccotnecderwniinthg gthreeahtaiznatredrsesot.f Wradhieatthioernsthtoe cinasetsheofvSercyhnweiedbeesrpgreaandd uJroaancihuimmstmalinwinilgl gisetasuqcuceesstsioorns that will presently be answered. Pneumopathies caused by radiation alrTeahdeyinbfeluenenrceefeorfreradditaotiaobnovaes.thOeucrakunseowoflecdagnecearbohuast sthmeallo.thIenr ceofnfencetcstioofn rawdiitahtiothneraopny,thleargluengdsoseasre(1v0e0r0y2in000thre.) fhoarmve obefepnnfeouumndontiotiscaaunsed cfhiabnrogseiss.inFrtohme luEnagsst Gmeornmiaancyasethoefrea ccohmemesistt,hwe hriecpholretdotfo adecahthro; ntihce pcnauesue odfusdteaotvherbaeinpgercioodnsiodfer2e0dytehaers.breathing of radioactive Conclusion daTtioonouforrprtheseentet ckhnnoicwalledpgree,vewnetioalnreaodfythheasvee daisefoasuens. Wpreevaernetioasn:yewt einknaowweatokoerlpitotlseitiaobnouast twohtyheoinrempeedriscoanl gmeutschthreemseaarcnhd. one does not. This question requires diaWgneoshtaicvse oaflrtehaedpyulrmeaocnhaerdy fdairseainsest,haendroethnetgreenwoleogarice mofakthinegdcioffnicsutaltnietsprtohgerreesisn. Wasetoareseavlesoralawoafreth, ehodwiseevaesre, ggeronuoplosgircefeexraremdintaotioanbowvee. mTuosgtedtheevrelowpitohthtehre clrioneicnatl 328 MEDICAL PRACTICES efuxnacmtiionnatidoinagmnoestthicosd.s,Inespitesciamlloystthaedvpahnycseidolofogircm,luwnge halal,teintothaeppfliyeldit enxoatmoinnalytioinns ltaobotrhaetoreixeasmbiunat,tioabnovoef poApubolavteioanllg, rwouepsneeexdpoaslseod itno tdhifisferfeienltd ekxepeonsuirneste. rna ttiooneaxlchcaonllgaeboinraftoiromnattoiosnolsvoe tohuart ceoamchmoonf upsroibnlehmiss oawndn caolruenadtryy pcoosusledss aptoplythein bpertatecrtimceenttheofknoouwr lewdgoerkiwnge population. BIBLIOGRAPHY General 21.. SPnaenucmeoscponciioaslies Acobnsstraaccrtsl, Voll'.tIuldl,e Ldoensdopnn,eu1m95o9. pmaatlh.iepsrofp.r,o1fe8s:2si5o3n-e3l5l4e,s 1(S95il7ic. ose excepte). Arch, 3. lAmlbeasharpyo,sCs.:pLoeusr alsethumr erspparroafteisosnio.neAllrecsh:. pmroabl. 4. pArlotsf.h,u7le5r:4, 1,B6.3;3,Y1a9r5m7.us, L.; Palmes, E. D.; and Nreeslpsiorna,torNy.: trAacetr.osAo.lMd.Aep. oAsirticohn. Iinndutshte. Hhueamltahn, 5. A77n:2d9e3rs,, 19W57.:. Soziale Probleme bei allergischen EOrfkf.raGneksudn. gdeinenasmt, 7B9e:4is8p8i,el1d95e8r.Asthma bronchiale, 6. oAfnddeirssaobnil,itWy . iHn.,caonadl Smcihnmerisdt,wWith. F.c:hErovnailcuaptiuoln7. ' Amnotnwaeryiledr,iseHas.e:. JM.Aa.sMtz.eAll.e,n777u:n1d45,H1i9s5ta9m. in nach Ipnajtehc.t,io7n6:6v0o7n, 1S9t5a9u.bsuspensionen. Arch. Gewerbe8. bBeapaadtehro,lEog. iWe .(:LEuningiegneemnepuheysPermob, leKmaedmdieurmG,ewDeesr mstaoddtu,r)1.95B6e,iph.. z1.72Z.bl. Arbeitsmed., Heft 3. Darm 9. iBnegrksaonnd, Jc.a:nTcehre osftattihsteicalul nign.vePstriogca.tioSntafoff Msmeoetk., 10. BMearylion,ClRina.,g7n4a:r2:06Y, r1k9e5s9p. neumokonioser. Svenska 11. LBekrnaarrtdid-Gnirnifgfeitnh,s,57:M31m57. -3G1-.;71,C1h9a5m6.peix, J., and dBeasldim'noi,isAis.s:uAressth(ma epprroopfoesssiodneel2p4arobcosenrtvaacttioanvse)c. 12. ABrucghy.i,mBa.:l. Bperiotfr.,g7e5:z2u7r2F, r1a9g5e7.der Staubretentions 13. fCahnigceklelait, dLe.rDLeuCng.;e.BMaaudnerk,aEv.dWel.;mC,h7o:u4x9,, J1.95D7e.; FZroornu,chOtm.: aInn,duRs.t;riaLl dffisleera,seWs o.;f tWheorcthhe,st:Ga.; coanmd m19e5n7t.ary on current problems. Dis. Chest, 72:683, 14. CBaerrsgtleenust,e.MA.r:chD.ieGaeswthermbaetpisacthh.e,n75R:4e5a,kt1io95n6e.n der 15. CEmarpstheynsse,mMu.:ndZBurronFcrhaigties ddeerr BKeragulseaultiet. tArvcohn. Gewerbepath., 75:285, 1957. 16. Dhoarusttr,eWba.n: dLe,unLg.;deBpeocskitmioannno,f fHin.;e daunsdt pWaratilckleens. A.M.A. Arch. Indust. Health, 76:179, 1957. 17. Dphayvsieicsa,lCp.roNc.e:ssD. eIpnostihteionSyomfpdousisutminotnheInlduunsgtsr:iaal PLuolnmdoonna, r1y96D0,ispe.as4e4s., ed. by King and Fletcher. 18. nDtianlndiearg, noLs.e: dKelriniLsuchn-grennktgraennokhloegitisecnh.e StDutitfgfearret, 19. D195n8n, epr., 3L62.:. Emphysem bei Staublungenerkrankkuranngkhne--it. EZmblp.hAysrebm. maelds., s7e:l1b3s7t, n1d9i5g7e. Berufs -- 20. kDrannnkeurn,gLe.n: PdneeruLmuoncgoen?ioKsernitiosdcheer SBtaeutrbalcuhntguenngeern umnedd.,V9o:r1s2c,hl19g5e9.zu ihrer Entschdigung. Zbl. Arb. 21. rFeeirniing,unJ.g, daenrdLuUnlgehelovvon, SVta.:ubUuenbderihdriee BSeesltbimst m19u5n9.g in Tierversuch. Arch. Gewerbepath., 76:630, 22. cFhlerotcnhiecr,brCo.ncMhi.t:isDiinsabreilliatytioanndto mduosrttaleitxypofsruorme. A.M.A. Indust. Health., 75:368, 1958. 23. Fmloectcohneior,sisC..InM.t:heRaSdyimolpoogsiicuaml doinagInnodsuisstorifalpnPeuul mdoonn,ar1y96D0,ispe.as7e2s., ed. by King and Fletcher. Lon 24. GanedrnVezo-iRsiine,uxC,.: CA.;n oBfatelgnaiurinerse,coEg.n;izFedoumrnaineirf,esPta.; tfiaocntioonf ponfeupmseoucodnoitousmisorianl mfoinremrsa:tioanses.ptiScemliqauinee Jh.oAp..M.AP.a,ri7s6,7:27144:01,08119-5180.89, 1958 (in French). 25. aGuefrsivnegr,scRhi.:edDeniee fSrtahuebnartReneakimtionveenrgdleeirchLenudnegne 26. TGilermvemrseu, cJh.,. aBneditrS. wSeilnisksoosne,fors.:chO.,m42a:1n,dr1a95p6n. eu- mNoonk-osniliiocsoetricnpnseiluikmoos.coNnoiordsi.s.MPedro.,c.55X:1I9I73,C1o9n5g7r;. 27. IGnodeutzs,t. AH.,eaalnthd, 7T:1su65n,ei1s9h5i7, . N.: A Bacteriological IInrrdituastti.onHeAalnthal,o2g0u:e16f7o, r19A59e.rosols. A.M.A. Arch. 28. mGoracuobninoesri,s.EP.:raCcolaosnsiifilceaktaiornstvSi,ys7te0m:10o9f, 1th95e8.Pneu 29. Gmreodn.eWmsecyherr.,, W57.::3D0,as19g5e8w. erbliche Asthma. Dtsch. 30. GParothsos,loPgaicual:l aCsuprercetsn.t Jc.oAn.Mce.pAts. 7o7f2p:5n4e6u,m1o9c6o0n. iosis. 31. pGnreoussm, oPcoanuilo: seAs.n Aim.Mm.Aun. olAorgcihc. aIpnpdrouastc.h Htoealtthhe, 32. 2G7r:o2s2s8,,P1a9u5l9,. and Smith, K. W.: The topographic dcoisntiroibtiuctilounngso.fDmisi.nCerhaelstd, u7s5t:s14i0n, 1s9o5m9e. pneumo33. aHnidggWinso,oId., TC.. TH.;.: CPoocphuralantei,onA.stLu.d; ieGsilosofnc,hJr.onCi.c; rfeosupnidrarytowroyrkedriss,eaasned. oAthercsoimnpSatraisvoenly, Doferbmysinheirres., 34. BHroilts.tJe.inI,ndEu.st. (MHeedra.,us7g6e:2b5e5r)-:268H, a1u95b9lu. ngenerkra- nkungen. Leipzig 1958 (Tagung in Erfurt, 1956). 35. Hofotlht,e PL.uFn.g: CPanuesuemdobcyonDioussist.. LInodnudsotnr,ia1l95D7i.seases 36. gHryadde.,MLeedr.o, y2:6:2D0i8f,fu1s9e59p.ulmonary fibrosis. Post 37. Jbluttnegne,neKr.krWan,,kuanngdenK, lBosatnedrk3t.teDr,arWm.s:taDdti,e 1S9t5a8u. 38. Kthhevaepffile,ctMo.:f iBnidoucshtermiailcadl umstetohnodsthein oargssaensissimng.' Higiena Truda, 4(4):28, I960. 39. tKhheupknheruinmao,cEon. iVos.:isMinectihdoednsceu-rsaetde.iHn igthieensatuTdryudoaf 4(4):7, 1960. 40. pKoisnigu,mE.onJ., InadndustFrlieatlchPeur,lmCo.naMr.y (Dediss.e)a:seAs. STyhme P19o5s8t.grCadhuuarctehiMll eLdtidca.,l LScohnodoolno,f1L96o0n,do(2n7,319p5a7geasn).d 41. lKuinngg, tEo. Jd.u, sat.ndInHathrreisoSny,mCp.osViu.:mReoanctiIonnduosftrtihael Pdounlm, o1n96a0r,ypD. i3se7a. ses, ed. by King & Fletcher, Lon 42. JK.leCihnrfeolndi,c MDi.s,.,a5n:d117G,ie1l9,59C.. P.: Pneumoconiosis. NORO 329 43. Kchluonstgeernkttbeer,r dWas.:ReTiniiegruenxgpsevreimrmengteelnledeUr Lntuenrgsue. 44. AKrocvhn.aHtskyyg,., M14.1:A2.5:8,Si1l9ic5a7t.oses. Moskva, 1957 (179 45. pLaagBeesl)l.e,RCev.,ieawnedd:BrHieiggeier,naH.T: rSuydnae,rg2i(s3ti)c:6e0f,fe1c9ts58o. f lauenrogs.olAs..MII.A. .efAferccths.oInndrautset. bHf ecaleltahr,an2c0e:1f0r0o,m19t5h9e. 46. lLimagitzees, sMur. lPe.: plLaan mmaldaidciaele.asAthrmcha.tiqmuael. eptrosfe.s, 47. 1L8a:n2e5,5,R1.95E7..: Chronic bronchitis and occupation. 48. BLraiwt.thJe. rT, uPb.erJc.,., a4n2d:11W, a1l9l5e8r., R. E.: Atmospheric Mpoeldlu.tiOofnf., a9n:5d, 1lu95n9g. cancer. Trans. Ass. Indust. 49. aLcutipoun, Nex.eGrthe.d; Vbyeliccearnt,aiCn.;pannedumOolcinoensicout,icVf.:acTtohres upuplomnontharey amciadcrompuhcaogpeosl.ysBarcicth. aJri.deIndcounstt.enMtsedo.f, 50. L16:b2l4i4c,h,195H9..-J.; Koch, W.; Sffge, K. H.; and NStoaurdbmesa. nFne, inkM.r:nigDeieStRuebseor(pKtaiolknspaeti,nSvepralteeiibsteenn s1t9e5i7n., Talk, Rutil). Beitr. Silikoseforsch., 50:1, 51. DLiebliRche,soHrp.t-iJo.;n Keoincvhe, rlWei.b;teanndStaNuobredsm. aDnine, AMu.: f1n9a5h7.me von Kieselgur. Beitr. Silikoseforsch., 50:11, 52. Mselarrcohgaenndes,.ME.:ssPaineduemcolpasastihfiiecastiporno.fePssrioocn.elXleUs nIonn tHerenlsaitnikoin,a1l95C7,on1g:1r5e7ss(BoinblioOgcracpuhpyatipoonsatl 19H50e,alptph., p1r7o0f-e1s9s1i)o.nVelildees:. MAracrhc.hamnadl,. Mpr.o: fL.,e1s8p:2n6e0u,m1o9p57a;thLieess 4p:n4e0u2m, o1c9o53n;ioHseysginonne seetlsreocguerniets. dAurcThr.aHvaigil., RFaadsea. 53. IMVa.rLksi,lleJ,.,19a5n5d(BNiabglieolgscrahpmhiydtp, pG. .2:8-S5t4u).dy of the htoyxdircoitgyenoasfe dutestchwniiqthue.useA.Mof.At.heArinch.vitIrnodudset. 54. HMeaayletrh,, E20.,:38a3n,d19R59a.ppaport, I.: Bronchitis and 55. EMmoprrhoyws,emPa.. EJ..;A.MMe.Ahr.h, o1f6,5:E1.2;2C7,as1a9r5e7t., L. J.; and DMeoprokseinti,oDn. Ain.: AHnumExapneriSmuebnjetcatls.StuAd.yMo.Af.AeArrocshol. 56. IMndotulsety., HHe.alLth.:, 1P8u:2lm92o,n1a9r5y8.function impairment 57. iNnagpenlesucmhmocidotn,ioGse.;s. NJ.eAls.Mon.A, .,E.17S2.:;15K91i,ng1,96E0.. J.; Aofttyqguaalrltez, Dan.;d aontdheYromgainnaetrhaalsn,frMom.: Tthhee lruencogvseroyf 58. rNaetss.is,A.AM. .AJ..: AMrceht.hoIdnsduosft. xH-reaaylthe,xa1m6:i1n8a8t,ion195i7n. 59. pNnoerudmmoacnonn,ioMsis.;. GKiogc.hT, rWud.;a,a5n:d22,M19d5e9r., E.: Die eRresogrepmtiiosnchetienrveSrlteiubbtee:n SKtaiuebseeslg. uSrptusntaddienQureairnz. 60. BOerietnr.stSeiilni,koAse.foJr.s:chU.,l6ti4m:2a1s, 1In95v9e.stigaciones sobre N19e5u9m. oconiosis. Medicina del Trabajo, 24:190, 61. Panedmbberrotnocnh,iaJl.:spCashmroninicbibturomnicnhoiutiss,coeaml pwhoyrskeemrsa. HAnealethp,id1e5m:5io29lo,g1i9c56s.tudy. A.M.A. Arch. Indust. 62. PweitnhdeErgmrapshsa, sEis. Po.n: Tthhee RPonleeumoof ctohneiosRiasdPiorloobgliesmt. 63. SPprirnincgi,fiFelrda,nk11:1.,S1ta9t5u8s. of the pneumoconioses. In t1r9o5d8u. ction. A.M.A. Arch. Indust. Health, 15:361, 64. gRleaisnb,lHse.r, aenidn BLriunnkgmenaenmn,phOy:seBme?komBemreunfskHraonhkl Wheitreznbuirng, d19e5r9.keramischen Industrie, Heft 6. 65. nSiaonsdese--r, cOlin. icAa.l: aCspuercrtesn. tJ.cAo.nMc.eAp.t,s 1o7f2:1p5n8e7u,m1o9c6o0. 66. oSfanthdeer,pnOe.uAm.o: cNoenwioesresco(nTcheepts19o5f8tRheampaatzhzoingienOersais tion). ]. Occup: Med., 1:7, 1959. 67. Scoannioo,sisT,,anadndtheOirsapnaatih, ogHe.n: esTisy.peRsepoofrtpsnoefumthoe 68. ISnasrtt,orfeolrli,ScEi.e,ncaendofScLoatbtio, uPr.:(TSotukdyioo),s5p5e:r2im7,en19ta5l9e. ee sdtaetlils'ticeonfsiusellm' aincpidoelmnzoandareellanberlloanchpoitpeoclarzoinoincae o(Mpirlaani od),i 48u:n7a04,m1i9n5i7e.ra di pirite. Med. Lavoro 69. Sbcehrunfesibdeedr,ingHte.:n UEmntpehrsyusecmhusnguennd dzeurr bFerraugfesbeddeis fnsgktre.ninEdm.pkheyrsaemm. bur.onGclhaist-isIndd.e, rHGeflat s2b.lWser.rzBbeurrug-, 1958. 70. AScthmnuenidgesro,rgHan.:e, Dinie Fb.erKufoleiclshceh: EHrkarnandkbuunchg ddeerr B(Leirtuerfsakturarvnekrhzeeiitcehnn,is2.S.A1u1f0!.9,).Jena, 1959. S. 620 71. SBcahyneernideirn, Hd.e:n DlieetztSetnaub5l0unJgaehnreernk.raSntkauunbg, e2n0:i1n, 1960. 72. Senchvrireonnkm, eHn.talH.:faScttoatrus.s oAf.Mth.Ae. pnAerucmho. coInnidousesst., Health, 18:365, 1958. 73. fSlrammmeka,tioJ.nsanodf Strhetekr,esJp.:iraCthorroynitcraicntduasntrdialpuinl monary emphysema. Prac. lk., 10:156, 1958. 74. tSitorneckaeurf, FS.iOJ..:-frDeiieeninLtruanpgeernitkoonhelaelsetaGubewuenbdstreihakreABebiwtra.nSdilluiknogsefdourrscchh.,g4e4ri:n2g1e, 1Q95u6a.rzbeimengungen. 75. Tinatrrgoadmucatdiozen, Kof. Sd.:usOtn totheaninimtraaclsh.eaGl igm.etThoruddoaf, 76. W2:5o6r,th1,95G8..; Durben, H.-H.; Ellersick, W.; Gast hBaruosn,chLia.l;spaasnmdenNebrreeiterK, ohWle.:nbeZrugrarbFeriategren viomn Untertagebetrieb. Beitr. Silikoseforsch., 44:1, 1956. pAnsbeuesmtoosciso,niojfsiibsr"oticcaulusendg bdyisesaisliecsa,teas,ndmi"xbeednigonr non-silica dusts 1. Cduosatl. WHeoarkltehr,s 1P5(n6e)u, m19o5c7o.niosis. A.M.A. Arch. In 2. AKdoerulbnadhsrc,hmGe.:lzeLru(nBgeernuvfsekrranndkehruenitgeondebreiSueiicniedm). 3. MAhsclmhra.rkU,nAfa.;llhBkr.u,c6e0,:6T5.,; 1a9n5d7.Nystrm, A.: PneuNmoorkdoinsikosM(etadlikcoins), v5i9d:287b,ea1r9b5e8t.ning av tljsten. 4. mAhoclmonairoks,isA.i;nBriurcoen, Tf.o;unandrdieNs.ysPtrromc., AX.:IIPnIenut. 5. ACohnlmgra.rkO,ccAu.p; .BHruecael,thT, .H; ealnsidnkNi,y4st:r36m5,, 1A9.5:7.Pneu5m9o:2k8o9n,io1s95h8o.s kiselgurarbetare. Nordisk Medicin, 6. TAalvlcisoastioss,ofGu. nPu.;suPaollnytiarakpisi,dAd.evEe.;loapnmdenTte.rzBirsi,t.B].:. 7. IBnodbuislet.vaM, eAd..,T1.2:e4t3,al1.:95T5.he Amount of Dust in RtheesiCdehniltdiarel nDs iHstreiaclttsh.ofGiAgs.biesLtanan.,d24i(ts9),Ef1f9e5c8t. on 8. ABsobhelsigto,seHd.;erJaLcuonbg, enG..;StaunttdgarMt (Tllheire, mHe).,: 1D96ie0 (166 pages). 330 MEDICAL PRACTICES 9. SBchowhleigrs,pHat.m: Slclehrw. ePreroMc.isXchIsItaIunbts.iliCkoonsegrb. eOi cecinuepm. 10. HBreiadlgteh-,DHaveilss,inSk.;i, a3n:3d10N,a1g9e5ls7c.hmidt, G.: A report oinn tphuereablsiemnceestoonfep. nBeurmit.ocJo.niIonsdisusatm. oMngedw.,or1k3e:r6s, 11. D19j5u6r.icic, I., and Savic, V.: La microhematurie des oPurovcr.ierXsIIdaInnst. unCeonmgri.neOcectupu.neHeuaslitnhe, dH'aeslbsiensktei., 3:324, 1957. 12. EunhdrhPaardtht,olWog.i,eadnedr OHcekideersmtaaunbnl,unWge.:. AZrucrh.KGlienwiee-r 13. rFbeehprea,th.WG.:eweUrebbeheryg.d, o7p7p:5e0ls4e,it1i9g5e9. Pleuraverkal kFuonrtgsecnhr.iRnfonltggeenbsterr.u, fSli3c:h1e6r, 1S95ta6u. beinwirkungen. 14. vGoanttndeerr,AHn.:thDraikeoRseu.ssP-rLouc.ngXeIIinIniht.reCroAngbrg.reOnczcuunpg. Health, Helsinki, 3:356, 1957. 15. mGolcmonmioes,isJ.,(GanradpShwitoesnisss,on,KAao.:liNnoosnis-s).ilicPortoicc.pnXeuII lnt. Congr. Occup. Health, Helsinki, 3:166, 1957. 16. GScrohsrse,ncPk,.;HW. Hes.;traicnkd, SMrs.ic,LR.;. PM.:cTNherenepyu,lmJo. nMary.; emffaeccetosuosf esayrnthth.etiAc.Msi.lAic.ateAsrcdhe.rivIenddufsrto.mHdeiaalttoh-, 17. 1H6u:3d1s7o,n,19J5.7.H.: Dust from Cement Works. Med. Officer, PS:351, 1957; J.A.M.A., 766:1358, 1958. 18. pHhybsinkearl,isOch.,-cahnedmiMschlelerU, nGte.:rsMucihnuenragleongisacnheeuinnedr TAarclkh-.SGtaeuwbelurbnegpeatuhn.,d44a0n, 1T95a7l.k-Hautgranulomen. 19. Kthaembmiteurm, Ain.oGus.: cOoaclcumpaintieorn. aAl.Mhe.aAl.thAprcrohb. lIenmdsusotf. 20. HKoeeallstchh,,7F3.::46Z6u, r19F5r7a.ge der "Graphitstaublunge". 21. K'bole.lsAcrhb, .F.m: eDd.i,e SS:tla,u1b9g5e8f.hrdung durch Flusspat. Zbl. Arb. med., 9:153-157, 1959. 22. gKeinvoilluoogtioc, siRgn.: oPf lneounra-ol cccualpcaiftiicoantaiolnenadsemaicroanetnot- p(6h7ylpliatgee-ass).bestosis. Acta Radiol., Suppl. 194, 1960, 23. LTalckhutrmacuhnt,d SHt.e,atiat,ndihreScBhemziiedht,ungKe.n zGu.m: AUsebbeesrt svoewrsiuechiharen WRaitrtkeunn. gBebietrim. Siilniktroasterfaocrhscthea.,le6n1, T19ie59r. 24. NLobrldimcha,nnH, .-JM.;.: KDocieh, RWe.s;orpStifofnge, eiKn.v-eHr.l;eibatnend 5S0ta:u1b, e1s9.5F7.einkrnige Stube. Beitr. Silikoseforsch., 25. RMoassss.iomneed, .RI.n,daunsdt., L(Tuvoorinnio,),R2.:5:S1i,li1c9o5s6i .da Mica? 26. PMreoick.leXjoIhIn,IntA. .:CoCngarr.boOnccuapn.d Hpenaeltuhm, oHcoenlsioinskisi., 3:335, 1957. 27. mMoenssairtey, Jt.a;lcRoseids,dina, cGl.i;niacnald aKnldeinefenlvdi,roMnm.: ePnutall study. A.M.A. Arch. Indust. Health, 20:408, 1959. 28. pMoolvnegreelli-dSicicaenmnaemnteoo,rilNie.v:i Sculinilcao-rpaadtioollooggiiaci dsua 350 cementisti. Folia Medica, 42:469, 1959. 29. RNeosrodrmptainonn, Mei.n;vKerolecihb,teWn .; SatnaudbeMs.deSrp,tEs.t:adDieine rKeiienseerlguunr dungdemQiuscahrzte. rBSeittru.bSei:likKoiseesfeolrgsucrh,.,Q6u3a:2rz3,, 1959. 30. aPcautttlee,toRx.icEe.;ffWectesdodf, bGl.acDk.;smanodkeB. uBrrgiet.ssJ,.FI.n:dTuhste. Med., 76:216, 1959. 31. dPeriosplaevrio,raGto.,rianddelBcaersmi,enCto.:. SRuallses.pnmeeudm. oicnodnuiosts.i, 32. R(Taoikrilnino,),N2.6:T16.:, 1M95a7t.erials characterizing the na tKuarreagoafnpdnaeuBmasoicno.nGioisgi.s Tinrutdhae, c3o(4a)l:4m8,in1e9r5s9o. f the 33. Sataidoknovosfkathyea,dNu.stI.:faActocrosminpapralatinvtes hpyrgoideuncicinegvadliuf 34. Sfearnednetr,typOe.s Aof.:ceRmoeenntt.gGenig.RTersuudrvae,y3(1o)f:39C,em19e5n9t. W19o58rk. ers. A.M.A. Arch. Indust. Health, 77:96, 35. Svocnhmfirdits,chKe.mG.,uanndd gLebcrahntrnattehm, HK.:aDoliien Wauirfkudnige SLiulinkgoesefournsdch.,da5s8, B1a95u8c.hfell von Ratten. Beitr. 36. SHe.eleEr.,: AT.alcO.p;neGurmyboocsoknii,osJi.s.SA.;.Ma.nAd. AMrcahc.MIanhdouns,t. 37. SHeepaklet,h, 7G9.::392Z, u1r959T. alkumstaublunge. Tuberk ulosearzt, 74:247, 1960. 38. sWchamtsoidnt,, AG..:J.P;nBeulamcko,coJn.;ioDsiosigin, AC.aFrb.;onanEdleNctargoedle 39. VMyaskkeorcsi.l,BrJi.t:. ].DIynndaumsti.scMheed.,V7e6r:2n7d4e,ru19n5g9e.n der LwuiendgeernhfoulntektUionnteenrsucbheuingZeenmneancthar5beJiatherrnen edruwrcieh sen. Pracovni lk., 8:85, 1956. Pneumopathies due to toxic chemicals and metals 1. hBeelrdyllaiutmMDasissaecahseuseatntsd IIntsstitCuotentroofl. TCeocnhfneorelongcye S79e:p9t1. -3206-7O, c1t.9519,. 1958. A.M.A. Arch. Indust. Health, 2. Agumindeuar, piMgsaryto Osu.:lfuTrhice arceisdpimraitsot.ryA.rMes.pAo.nAsercohf. 3. IAnrdcuhsatn.gHelesakaltjha,, 1L8:.40N7,. 19&58.Borisenkowa, R. V.: vUonnterIsnudcuhsutnrigeesntaubberaudsie Mhyegtaielnl-iLscehgeierBuenwgeenrt.unJg. H19y5g7.. Epid. Microbiol. Immunol. (Prague), 7:441, 4. MBaeadd.eSr,acEh.veWrs.t:.,L5u2n:1g2e8n,s1c9h56d.en durch Isozyanate. 5. bBlauandgeern, eEr.krWan.k: uHngaertnm, eBtaalnl-dLu3n.gEend.. Ibny DJietteSntau& Kmelods.t,e9rk:33tt,er1,95D9.armstadt, 1958, p. 531; Zbl. Arb. 6. fBsakaradnerk,heEi.teWn..:SNicehueeres Abrbereidt,ie7:w23ic,h1ti9g6s0t.en Beru 7. ABlaurmthi,nGiu.m; Flurnikg,e.WD.; tsacnhd. SMcheedi.deWmsacnhdre.l,, 5H7.::11D1i5e, 1956. , 8. AB.e;ckalnakde,FMre.ckR, .;C.GoCl.d: mTahnen, lHon.gI-.t;erRmae-eBffoecstms aonf, e7x6p:3o9s8u,re195to7. nitrous fumes. Am. Rev. Tuberc., 9. wBietnhoiastr,goCn.-Pa.r,chandweFlrdainngt,. RP.:roMc.edXiIcIal Ienxtp. erCieonncgers. 10. BOicscteurp,. FH.;eaKltlhav, iHs,eGls.i;nkKi,3h:l3e8r,7,H1.9;57a.nd Wittgens, Hau.:f ZZiunrkcGhreowmearbtbeatosixsi.kAorlocghi.eGveownerAbenpstartihch.,s7st6o:5ff6e7n, 11. B19l5o8o.m, G., and Swensson, A.: The reaction of the sthioronsmboofcytseusbmtoicrionstcroapviecnoupsalryticliensj.ectAedctasusMpeedn. 12. SBcoacncdia.,, 7D6.2::42P3a,to1l9o5g8i.a de la soldadura elctrica. 13. MBoendn. eTilr,aJb.aAjo.,; 2K3a:1z6a,nt1z9is5,8.G.; and King, E. A.: A fooxlildoew-fuupmes.tuBdryit. oJf. Inmdeunst.exMpeods.e,d76t:o135c,ad19m5i9u.m NORO 331 14. pBirctcuhrenero,f Lpn. eu&moMcoanuitonseirs, inB.:weBldreornsc. hPograracpohvniei 15. Bleokoatr,stAvi., 1C1.::2V33e,rg19if5t9u.ng mit Vanadiumpentoxyd. Ned. Tschr. Geneesk., 101:2124, 1957. 16. Btiorensliinn,bAe.ryJl.l,iuamndfaHcialirtriiess,. WSu.mBm.:arHyeaolfthtenpryoeteacrs o1f9:59e6x,pe1r9i5e9n.ce. A.M.A. Arch. Indust. Health, 17. Bchuieaslse, uHn.d, aasnthdmLoeidrneeBr,roRn.c:hiUtiesbienrdAerstchhmema isbcrhoenn 18. ICnadmusptbrieell., ZI.rePnrevRen.;tivCmasesd,.J(.ZSu.r;icCh)h,ol5a9k,, 1J9.5;6.and MKeahno.e,AR.M. .AA..: AArlcuhm. inIunmdusitn. tHheeaEltnhv,ir7o5n:m40e4n-4t0o6f, 19. C19e5m7.ber, H.; Watson, J. A.; and Grucci, T. B.: ' aPcutlimvaotendaryclaeyffepctasrticflreosm. Ar.aMdi.oAa.ctiAvrech.thaIlnldiuumst-. Health, 75:449, 1957. 20. AC.hMol.aAk., AJr.:chT. hIneduansta.lyHsiesalotfh,tr7a9c:e2s05o,f19b5e9r.yllium. 21. pCohirsiosnteinnsge.n,AF.M. .CA.., aAnrdch.OlIsnodnu, sEt.. HC.e:aClthad, m1i6u:m8, 22- C19o5t7te. r, L. H.: Treatment of cadmium poisoning w16i6th:135e,d1a9t5h8a.mil calcium disodium. J.A.M.A., 23. mCraelpaettti,a Md.a, annadvadGiasffunreii, Epu.:litAoriprodpi osciatlodadieellaa nafta. Lavoro e. med., 10, 1956. 24. anCdurtiRs,asJm. uKss.e;n,BaHue.r, KH.:elePnue;lmLoonoamryansd,iffSuasliloien; ccaarpbaocnity msotundoixeisd.e Ib. reaaths-imhoplldifiniegd. Atemch. nJiq. uMe edof. 25. SDeai.l,h2a3m6n:5,3T, .1:9C58h.lorine dioxide toxicity in animal eInxdpuersitm. eHnetaslthan, d75:i1n0d1u,s1tr9i5a7l. risks. A.M.A. Arch. 26. DG.eicEh.m: aAncnu,teWe.fBfe.c;tsKoefplinnitgreor-,oMlef.inI,s.; uapnodnLeaxnpieerr,i m75e:3n1ta2l, 1a9n5i8m. als. A.M.A. Arch. Indust. Health, 27. DdernschSei,ntHer.a:nlZaugrenFrasgaearldenrdiSsctahuebrgeEfisherndhungtteinn w19e5r9k.e. Arch. Gewerbepath. Gewerbehyg., 76:666, 28. nDonn-npenre,uLm.o, caonndioHticarlduyn,gRl.e:siPonnesudmuoecotoniointihcalainndg xd-ursaty anadndS02mfuomrbeisd-farnoamtombuicrnalingstcuodkiee.s.CliAnirccahl., Gewerbepath. Gewerbehyg., 76:644, 1959. 29. uEnhdrlicahrebre,itHsm.,eadnizdinPisibczh,eWM.: aIsnsdnuashtmrieehnygbieeniiscdheer Vscehruwtze,n2d7u6n,g1v9o5n6 I&so7z,ya1n9a57te.n (Desmodur). Arbeits 30. FCiasdchmeiru,mR,.QEu.e:ckGseilwbeerr,blAicrhseenVuenrgdifithurnegeVnerdbuirncdh u1n94g6enb.is U19e5b6e.rsCiclhaut sthbael-rZedllieerfeVlder,1f9fe5n8.tlSicchhurnifgteenn Bd.ergGleeusteellsec.hVa.,ftHeDfteu6ts(2c0h2erpagMese)t.allhtten- und 31. rFeriineebmel, PHh.t,alasnudreGanrohsysd, riEd.: uZnudr RToohxpizriotdtukvteonn aGueswedrebrepiantdhu.,st7r4ie:4ll6e5n, 19P5h6t.alsauresynthese. Arch. 32. Fderinebedlu,rHch., anneduaLrtigcehtrLatahc,keH.u: nGdesSucnhdahuemitssstocfhfe. Dlsch. med. Wschr., 67:980, 1956. 33. eFirniefabcehl,e HC.,heamndikaSltieeinn, hAe.r:vZorugrerGuefneneseen dAesstdhumracsh. Vpaetrhsu.,ch76e:6m20it, 1p9-P59h.enylendiamin. Arch. Gewerbe 34. Fmriiubmerg,poLis.:onEindgat.haAm.Mil.Ac.alcAirucmh-.diIsnodduiisitm. Hineaclathd, 13:18, 1956. 35. mFriiubmergi,n Lm.:anDienpocshitrioonnicapnodisdonisitnrgib. uAt.iMon.Ao;fAcrcahd. 36. IFnrdibuesrtg.,HLe.a: ltChh, r1o6n:i2c,1,ca1d95m7i.um poisoning. A.M.A. Arch. Indust. Health, 20:401, 1959. 37. vGaapgoeu, r.J.BriCt..:J.TIhnedustto.xMiceitdy., o76f:1e1p, o1c9h5l9o.rhydrin 38. FG.a:lyP, nPe.u;mRooncihee,chLr.o;nBiqouueviienrt,eJrs.;titaineldlePdeirfrfiuns,e L:.i eAvroclhu.timonal.mporortfe.,ll7e6:c3h0e1z, 1u9n57.metalliseur au zinc. 39. fGrolmmmceh,lJo.r,inaend dLiuoxniddger.enA, .KM.-.DA..: HAeraclht.h hIanzdaursdts. 40. HGleamltmh,e,76J.:,16a9n,d1S9w57e.nsson, A.: Tierexperimentelle sUantmteorssupchhruengevnonbeFrerdreonsiliSztiauumbwienrkedne.r ASrtbaeuibt lKulnogsetenrekrktrtaenr,ku1n95g7e.n, Band 3. Herausg. Jtten & 4L aGlulmmiomseis, Ja.,nadndpnSewuemnosscoonn,ioAs.i:s Ciansesthoef stiudnegrostseisn, ccuarpb.idHeeatoltohl, iHndeulssitnrkyi., P5:r1o6c6.,X1I9I57I.nt. Congr. Oc42. bGaormiubmos,duBs.:t. PPurlamcoovnnairyLenkoadrustlvait,io9n:39b9y, i1n9h5a9l.ing 43. rGernacye,, Et.oxLiecBit.y:, Ohxaizdaersd.ofAn.iMtr.oAg.enA: rtchhe.irInodccuusrt. 44. HHeagallitnhd, ,19O:4.:19,Lu1n95g9.changes in electric welders. 5P:r1o6c9., X19I5I7.Int. Congr. Occup. Health, Helsinki, 45. IHsoacmyaa,naGte.s.MA.:.MSy.Am.pAtormchs. iInndWusotr.kHeresaEltxhp,o7s6e:d23t2o, 46. 1H9a5m7.lin, L. E.: Siderosis. J. Oceup. Med., 7:79, 1959. 47. oHvaemr lainp,erLi.odE.o:fSeiidgehrot syise:arasdodnitisoixntayl-noinbesefrovuatnidonrys c1l9e5a9n.ing room employees. J. Occup. Med., 7:79, 48. sHeaasred.yJ,.HC.hLro.,n.aDndiseSatsoee,c9k:l1e5, 2J,. 1D95.:9.Beryllium di 49. nHoassiesgaovfa, cKh.ro(nanicd Tsuelipsihnugrer,dJio.,xdidisecusinsitoonx)i:caDtiioang. P5:r2o7c1., X19I5I7.Int. Congr. Occup. Health, Helsinki, 50. HGuewsteernb,epKa.:th.H, a7r6t:m72e1ta, l1l-9F5i9b.rose der lunge. Arch. 51. cIaanzinoanceohaec,utAa.,daandanMhiadzreildlae dmiaBleoisccao,inMl.:avIonrtaotsosrii52. Jdoehl npsotortnoe., LRa.v.Tu.:mTanoloue(nNea-2p.o4l-iD),ii6s:o4c0y4a,n1a9te5.6.clin 53. iKcaalrpfoeva,turBes.. IDn.d:usAt.nMgaebde.n, 26z:u33r, 1to9x57ik.ologischen 2C2h:1a4ra4k:7te4r,is1t9ik57v. on Methylchlorakrylat. Gig. i San. 54. dKearspHareorvs,teAll.uAng.: PvroonblVemulekadneirsaAtirobnesiatskhzyegleieranteorbeeni 55. K(Tlaiuvrisa,mG, .:KaApmtamkso).niGakigv.ertrguifdtuan, g7e:2n4,un19d57i.hre Fo Algrecnh. uTnotxeircolB.,e7r7:c1k5s5i,ch1t9ig58u.ng neuer Kasuistik. 56. UKlrasvacish,e Gd.e; r KThholemr,assHch.;lacaknednpnBeiusmtero,nieF.:unDteier bmeasnognadnehrearltigBeenrcSkcshilcahctkigenubnegstadnedrteVilea.naAdricnh- . uGned 57. wKeleribnefpealdth, .M, 7.,5:a3n5d5,G6i0e7l,, C19h5.6-P1.9:5C7.linical manifes otaftieoxnpsoosufroez.oAnme .poJ.isMoneidn.g:Scr.e,p2o5r7t:6o3f8a, 1n9e5w6.source 332 MEDICAL PRACTICES 58. kKaoreblisdceh, uFn.d: GHeasrutmndehtaeliltess.chZbdl.enArdbu. rcmhed.M, e9t:a3l3l, 1959; J. prophyl. Med. Soz.-hyg., 3:1, 1959. 59. SKtuanbkileel,, DA..E.M; .S; auMnduerrtsh,a,J. EP..; Fa.;ndDWikielmls,usJ,. HH..:; SAormche. pInhdarumsta.cHoleoaglitcha,l 1e3ff:e3c4t6s, o1f95d6i.borane. A.M.A. 60. fKtuuntsgchdeurar,chW.D: isEsionusegiagse.nMartiitgt,ersFtaelrlr.eiSnaenr Vveerrwgi., 61. 5L7a:c2h2n8,it,19V5.6:. Zur Therapie der Reizgasvergiftung. Zbl. Arb. med., 5:177, 1958. 62. ALeluicnhteinr,iumF.l:unZgeur unDdiffeMreonrtbiaulsdiaBgoneocske. Fzworitsscchhern. 63. RLevnitngseknasst,r.G, .5J4.:;57P1o,ll1is9,5A6..; and Novick, W. J., Jr.: ADricshtr.ibIuntdiounst. aHnedalethx,cr1e4t:i3o4n6, o1f95p6.oranes. A.M.A. 64. AL.eMw.iAs,. CA.rEch.:. TInhdeusbti.olHogeiaclathl ,ef7f9e:c4ts97o,f1v95a9n.adium. 65. iLnisnkdagrseynn,pSu.nkAt.e,r apnad fSrwamensstsollnn,inAg.: oYchrkebsemaerbdeict-66. nLiinnggeanv, pMlaasrtieer-.LSovu.isLe, kaanrdlidSnuinngdeenll,, 5C5.:2G22.:7,L1u9n5g8-. jfehranltdigrinlugfatr. NiaokrtdtiasgknaMeedfitceirn, i5nfVa:n1d97n4i,ng195a7v. ol67. (Lboowraen, e)H.inJto.,xiacnadtioFnreienmmana,n.G.A: .MB.oAro. nArhcyhd. riIdne 68. dMuasct.haHbeealil,thM, .16E:.5;2G3,dz1e9l5d7z.e, E. G.; and Mgeladze, Tm.anGga.:noCkolinniiocsails. pGicigtu. rTeruadnad, 4w:4o8r,k19c6a0p.acity in 69. Mlunagn.n,BrBit.. TM.,eda.ndJ., L2e:9c2u1ti,er1,95E7.. R.: Arc welder's 70. Mtoxarickist,y Jo.f, daunsdt wNiathgelusscehmofidtth,e Gin.: vSittruodydeohfydtrhoe g2e0n:3a8s3e, t1e9c5h9n. ique. A.M.A. Arch. Indust. Health, 71. Mbaesrsmdainen,biWolo.:gisEcxhpeerWimireknutenlgle vUonnteVrsauncahduinnvgeern bindungen. Arch. Toxicol., 76:182, 1956. 72. gMeanssmbaenrnd,ieWt.o: xTikieorloegxipsecrhiemWenitreklluengUnvotenrsRucahuuchn ekntr,oddeine ebneitsteShchewn.eisAsrecnh.mGitewkearlkbbepasaitshc.h, en74:E29le1, 73. M19a5s6s.mann, W.: Untersuchungen ber die Mbioeldo.g, i7s2ch7:e40W7,ir1k9u5n6g. des Polyaerylnitrils. Z. exper. 74. dMesasLsmunagnenn,gWew.e, baensdnaPcihlgirnimtra,trKa.c:heDaalesrVInejrehkatlitoenn vGoenwMerbanepgaanth-.I,V7-O5:2x0y3d, u1n9d56.Chrom-M-Oxyd. Arch. 75. oMpcaLqauueghdluinst,s.AI.n I.theG.:SyImropnosiuamnd oonthIenrdursatdriiaol PLuolnmdoonna, r1y96D0,ispe.as1e4s6,. ed. by King and Fletcher. 76. uMseeikolfejcoahlnci,nAed., aalnudmPinoasnienr, cEh.:inTa hbeisecfufietctpolafcitnhge Monedt.h,e74h:2e2a9lt,h19o5f7.the workman. Brit. J. Indust. 77. zMuellnssikigoevna,KEa.dmA.i:umA-nguanbdenVzaunradBiuemstigmehmaultnegs ddeesr Luft in Industrierumen. Gig. i san., 21:25, 1957. 78. dMuosztreinatlseavear,osNo.lsVo.f: wHoylgfrieanmic. Gchiga.raicStearni.s,ti2c2(o4f):2in5, 1957. 79. tMraigndzeunr, CHa.d; mBiruumckvneregr,iftCuhn.g;. aAnrdchS. iGmeoinu,erJb.:epBatehi. Gewerbehyg., 77:531, 1959. 80. wMoitrckheer.ll,BJr.i:t. PJu.lmInodnuasrty. Sfiabfreotysi,s7i6n:1a2n3,a1lu95m9i.nium 81. oMf itotlzeorn,eS..;AK.Min.gA,.MA.;rcahn.d IBnudruksht.arHdte,aBlt.h: ,To7x5:i1c9it1y, 82. M19o57g.ilevskaya, O. Ya.: An experimental study of ttohrey eoffregcatnso.f Graigre. imseatna.l,s2o5r:3e0d, u1s9t60o.n the respira 83. LMuonsgcehninvsekria,nGde.;ruJnugreisnch,beAi .,SainndteRrheianrl,tmWe-:taDlli-e 84. AMrobleitioterr,n.L.A; rcMho. sGinegwere,rbMep.;alhB.a, r7th6e:6l,97J,.;19H59e.yart, dHe.; alanmd inPoeirrineet,t Gl.e:uRrecchaepracchiets supratlheosgponues.siLreess spiadgerso)s.es pulmonaires. Luxembourg, 1957 (127 85. LMuonsgcehninvsekria,nGde.;ruJnugriesnch,beAi .;SianntderhRaertimnle, taWll.a:rbDeiie86. Ntearnk.anAisrkchi,. SG.,eawnedrbNepamatihk.,i, 1S6.::6S97y,m1p9t5o8m. s in work e1r9s58e.xposed to isocyanates. Rdkagaku, 34:980, 87. sNuelfbaetl.unAgr,chW. .G: eAwekrubteepaVtehr.,gi7ft5u:5n8g1,m1i9t57D. imethyl88. SOtyanannogsuirse.n,BeHni.g; nHpandeduamdo, coRn.i;osaisndowMinagasst,o Hin.: ahnadlatieoxnpeorfimtienntadlussttuadnides.fuImnde.usIt.. eMnveidr.o,nm27e:n42ta7l, 1958. 89. gPaennesleveri,ntRox.:icaDtiioagnn.osRisepaonrdt otrfeaatmceanste.ofA.mMa.An. Arch. Indust. Health, 76:64, 1957. 90. mPoorntealiar-eGomeqsu,elFq.u: eLs aprreoadcutiitosn idneduls'tarlivelso.le Ppruocl. X19I5I7.Int. Congr. Occup. Health, Helsinki, 3:311, 91. ivnohnalPaotisot-nLianvgeno,ljaMealrliee-rLoouljicshe:altLigunlgusfkt.adNororedfitsekr Medicin, 39:290, 1958. 92. mPootneyryapeevnata, cGh.loEri.d:eT. hGeigt.oTxircudpar,op2e:2r2ti,es19o5n8. anti 93. QKuloitlilnig,aPn.,: JT.hJe.;toBxoiccihtye,oRf .ozDon.;e Ffoalrky, oLu.ngHc.;hiacknsd. 94. AO.eMtt.eAl,. HAr.:chG. eIsnudnudsht.eiHtsegaelftahh,rd7u5n:1g6,d1u9r5c8h. 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Roofepnntgeeunmool., 79:189, 1958. 9. LFaroesgt.,, J7.7,5a:1n3d83G, e1o9r5g6.. J.: Taerskerlunge. Ugeskr. 10. eGrrsoeatsncheAl,stHhm., aandbrTonrecniaslee, En.:acThodUemingeasnDgrumckit N37a5s,sz1e9r5s8t.ubemitteln. Arch. Gewerbepath., 16: 11. GOxuypgtae,n Aco.nsSu.;mFpetirorins,ofBm. aGle.;Inadnidan Rjuatoe, wMor.keNrs.:. 12. AK.lMun.Ak.er,ArWch.:. ZInudruFsrt.agHeedaeltrh,t2i0o:l9o6g,ie19u5n9d. Path omgaesn.eSsechdweesizs,omgeenda.nWntsecnhrB.,ac5h7e:7r-14u,n1d95M7. llerasth 13. eKtiyoulongg,icVal. Afa.c:toDruosft oocfctuhpeatkiounkaklerpsniteeumshoacleonaiossaisn. 14. LGoigw.ryT,ruTd.a,, a7n:4d4, S1c9h5u9m. an, L. M.: "Silo-filler's Jd.iAse.Mas.eA"--., a76s2v:n1d5r3o,m1e95c6a.used by nitrogen dioxide. 15. ME.:urrAany, oRu.;tbrDeiankgwoafll-Fwoeradvyecre's, Ic.o; uagnhd aLssaoncei,atRed. w77i:t1h05ta, m19a5r7in. d seed powder. Brit. ]. Indust. Med., 16. ePiensetarlozMzio,dCel.l:scFherebirnielereiGrduuprpcehnerIknrhaanlkautinognenvoinn mwaitsseSrch(iBmemfeeulpcihlzteernfiekboenrt)a.mScinhiweertiez.mMBede.feWucshchterr., 89:710, 1959. 17. EPoxlpiaekri,mKen.;teGlleiithUerntt,erHsu.,chaunndgeSnchzaunrzenFbraacghe, dHe.r: Gbeehtyregi.d, es7t7a:u5b1l9u,ng1e9.59A. rch. Gewerbepath. Gewer18. Ranodache,nvSi.roAn.m, aenndtalScshtuildliyng,ofR.bySs.siFn.o:siAs cinlinitchael L77a:n1c,as1h9i6r0e. cotton industry. Brit. ]. Indust. Med., 19. sSics.hiIllningth, eR.SySm. pFo.:siTumhe oenpidInedmuisotlroigayl Pofulbmyosnsianroy Dp.ise1a8s5e.s, ed. by King and Fletcher. London, 1960, 20. Ssics--hilalidnvge,nRtu.reS.aFn.d: mThiseadevpeindteumrei.o,lJo.gyOcocfupb.yMssiendo., 7:33, 1959. 21. Sertso.ttB, rHit..: ]P. uInlmduosnta.ryMeddis.,ea7s7e:2a3m, o1n9g58st. sisal work 334 MEDICAL PRACTICES 22. Scemnetrtaantiionn, Nof. tIh.:e Tloheess mduaxstiminal thpeermaiirssoibflecocttoonn 5. dBiasetrtijberu,tiAo.nMa.n; dDaremteronnti,onC.;oafncdhrBoumdiaucmz, Vin.: mThene 23. sTpiilnlenri,ngJ. pRla.:ntAs.nGiingv.esTtriguadtaio,n5:o5f3,by19ss5i9n.osis in a a1n95d9.animals. A.M.A. Arch. Indust. Health, 20:136, r1a9y5o8.n mill. Trans. Ass. Indust. Med. Off., 7:157, 6. BBuadetajcezr,, AB.. AM..:; ELfofewcnteoy,f Jc.hrFo.;mSiutemffeeo,nMin.Dci.d; eanncde 24. TMootrtaenn,, TR.. JS..:; FRaerimd,erD's. lHun. gS,.;reDpaovrits,oHf .twDo.;caasneds Ionfdluusnt.g Mtuemd.o, r2s0:i1n24m, i1c9e59a.nd rats. A.M.A. Arch. Jin. wMheicdh., l2u5n:8g03b,io1p9s5i8e.s were performed. Amer. 7. Bcaindcsetrru. pT,raPn.s. LA.s:s. OIncdcuuspta.tiMoneadl. Ocfafu.,se9s:2,of195l9u.ng 25. iTnuvfefsntieglal,tioPn. iGn.t,o atnhde aDciuntgewraells-pFiorardtoyrcye, reIa.:ctiAonn 8. LBuonhgliegn,krHe.b,seasndbeJai codbe,utCs.c:heDnie AHsbuefsitgarkbeeititedrnes. Btoritth. eJ.inIhnadluastito. nMoefd.t,am14a:r2i5n0d, 1se9e5d7. preparations. P5:r3o0c8., X19I5I7.Int. Congr. Occup. Health, Helsinki, 26. SW.:assReermchaenrcnh, eMs .;eBxupgeeriamg-eMntiahlaeisl, Gco.;nacnedrnIaonstub"alsa, 9. hBerravuonr,gWeru.:feKnredbusrcahn HArasuetn.unDdtsicnhn. eMreend.OrWgascnhern.,, Pmraolca.diXeIIdeIsntf.ileCuorsngert. dOecscutpis.seHuresaldthe, cHhaeulsvinrek"i., 5:374, 1957. 10. SB3r:o8w70n,in1g9,58E. thel: Harmful effects of ionising ra diations. Elsevier Monographs: Industrial Toxic 27. WBaeugmmwaonlnl,staTu.b; luGnaglele. tti,ScPh.:weainz.d AMmerde.in, WHs.chPr..:, 88:437, 1958. 11. ACgeemnbtse.r,AHm.:stBerrdoanmch, o1g9e5n9i.c carcinoma from radio active particulates. Second United Nations Con 28. ZAanpnroinpio, sDd. e(alnad"WFiavsrseermdeasnnc,erMea,,lesD"isdcuesssitorna)v-: fGereennecvea, o1n95t8h.ePPapeearceAfu/lCoUnsfe.s 1o5f/PA/t9o0m0.ic Energy. Halleeaulrths, dHeselssiinloksi., 5P:r3o8c6., X19I5I7.Int. Congr. Occup. 12. CMheiduirccion,a MG.utuAa.:listLicaav,or4o:Voel. t1u4m, o19ri5.9 A(3r7c2hipvaogesd)i. Infectious and parasitai pneumopathies 1. Drankin, D. I., and Gerasimova, M. M.: Brucello VHiedlesinaklsi,o:14P7r,o(cF.r.X),U139In, t(.EnCgoln.)g,r1.9O57c.cup. Health, 13. Davies, D. F.: A review of the evidence on the 2. sGisroassn,dPo.;cWcuepsattriiocnk., GMi.g.L.T; rMudcaN,er2n:8e,y,1J9.58M. .; and Pittsburgh, M. P. H.: Experimental Tuberculo- rJe.laCtihornosnh.ipDibs.e,tw77e:e5n79,sm19o6k0i.ng and lung cancer. 14. Doll, R.: Occupational lung cancer. In the Sym p19n:e3u2m0,oc1o9n5i9o.sis. A.M.A. Arch. Indust. Health, 3. 5H7a5r:r7i0s9, ,H1.9J6.0:. Treatment of Brucellosis. J.A.M.A., pKoisnigumandonFIlnedtcuhsetrr.iaLl oPnudlomno,n1a9r6y0,Dpis.ea2s0e8s., ed. by 15. Doll, R.: Occupational lung cancer: a review. 4. Jbuenitaekrn, . GA-trchL.epGtoewspeirrbeenpinaftehk.,tio15n:e5n65,be1i95K7.analar 16. BDrviitz.k]o.v,InPd.uPst.:. MOcedcu.,p7a6ti:o1n8a1l, c1a9n5c9e. r. Gig. Truda, 4(3): 3, 1960. 5. AKrcthh.e,GJe.:weDrbieepLaethp.t,os7p7i:r3o1s6e, a1l9s59B. erufskrankheit. 17. aEncdkaLrdotn, dRo.nE, .1:9I5n9d. ustrial Carcinogens. New York 6. mKioncgo,niEo.sisJ..:PRroecc.eXntIIRIenset.arCchonginr. IOnfceccutpiv. eHPeanletuh, Helsinki, 7:283, 1957. 18. Efilellidn,g1e1r1,.,F1.9:57M, epd.ic2a2l4 Rffa. diation Biology. Spring- 7. aKnindg,MEi.tcbJ.i;soYn,ogDa.natAh.a:n,EMxp.e;riHmaernrtiasol n,infCe.ctiVv.e; Pneumoconiosis. A.M.A. Arch. Indust. Health, 19. Enisopsiinso. sM-Peedr.ezy, sDeg.:. tCraanbcaejor,p5u:5lm, 1o9n5a7r. y neumoco20. Finkel, Miriam P.: Internal emitters and tumor 76:380, 1957. 8. mRaemntsaoyf, Jp.neHu.m, oacnodnioPsiinsesc, oAm.:pliRcaetseudltsbyof tturbeeart iAntdoumcitcioEn.nerPgryo,c.GeInnetv.a,C1o9n5f5., VPoela.c1e1f.ulNeUwseYsorokf, 1956, p. 160. 9. Scuclhosipsp. eBrtr,it.RM.: edL. uJn.,ge2n:t3u4b5e,rk1u95lo9.se als Beruf skrankheit bei Metzgern und bei in Landwirt 21. Gpaatlhleigeso,duJ.e tDo.:duPsut.lmProonca.rXy UleIsniotn. sCoinngrp.nOeuccmuop. Health, Helsinki, 5:378, 1957. 5sc2h:4a1ft7,b1e9s5c8h.ftigten Personen. Z. rztl. Fortbild., 22. BGroiltd. bMlaetdt,. BMu.ll.W, 7.:4:1O3c6c,u1p9a5t8io. nal Carcinogenesis. 10. Sbrpuincekl,losWis. inW.h: umCuanrrebnetinsgtsa.tuJs.A.oMf .Ath.,er7a7p2y:69o7f, 1960. 23. Glyrmospshe,knoHte.:n uMndiscLhusntaguebniknrdeubrsa.tiFornankdfe. rZ. HPialtuhs.-, 67:220, 1956. 11. mTearlziainn, pnAe.umLo.n: itisPsi(tPtaOcoMsiPs--) ovrnirautsheossisi--n mmaamn, 24. BHualdl.d,o7w4,(2A),. 1(e9d58.).: Causation of cancer. Brit. Med. Immammumnaolls. a(nPdragbuired),s.2:J1.29H, y1g9.58E. pid. Microbiol. 25. aHnadrrisW, eWin.steBin.;, BMre.sliSn.,: AE.nvJ.i;roGnmlaeunbtearlmhaanz,arBd.s; Lung cancer due to occupation and radiation Aas.sMoc.Aia.teAdrchw.itIhnduthset. Hmeialllitnhg, 20o:f36ub,ra1n9i5u9m. ore. 1. C19a5u8s.ation of Cancer. British Med. Bull. 14(2), 26. cHaunecpereirg,enWes.is.CX.: . Ecaxnpceerriimgeennitcalefsfteucdtsieosf icnhrommeitatel 2. Awsokrk-Uerpsm. Dariks., CE.h:eBst,ro2n7c:4h,ia1l9c5a5r.cinoma in printing ocarevitryoasotf deraptoss.iteAd.Min.Am. uAscrlceh.tisIsnudeuasnt.d Hpleeaulrtahl, 3. Afezrihnbgel,frSo.mI.: tOoxniccapnnceeurmdoiasgclneorsoissesi.n Hpaigti.enTtsrusduaf, 78:284, 1958. 27. Irmscher, G.: Ueber einen Todesfall an chro 4. 5B:a1r1b,o1r9ik5,9.N. et al.: Carcinoma of the lungs in nuinsdchebretPansetruamhloenniaektinvaecmh In"hInadlautsiotrniesvtaounb"alphvao-r e7l0e:c4t1r3o,ly1t9ic58.chromium plating. Prac. Lkarstvi, 5ru2n:1d73220, J1a95h8r.en. Das Deutsche Gesundheitswesen, NORWOOD 335 28. WJamaleess, cWoa.l-Rw.orLk.e:rsPwrimitharpyneluunmgoccoannicoesrisi.nBrSiot.utJh. Indust. Med., 12-.ST, 1955. 29. eKxeongneanwoauys,faEc.,toarsndinLtihnedsceayu,sAat.ioJn.: oSfolmunegpcoasnsicbelre. 30. BKroiet.lscMhe, d.F.B: ulDl.e,r14A:1rs2e4n, k1r9e5b8s.. Zbl. Arbeitsmed., 31. SM:1c2L9a,u1g6h1l,in1,9A58.. 1. G.: Iron as a Carcinogen. In ethde. SbyymKpionsgiumandonFIlnetdcuhsetrr.iaLl oPnudlomno,n1a9r6y0D, ips.ea1s6e2s., 32. MPuecdc.inLia, voCr.o: , L51e:18p,ro1b9l6e0m. a della cancro-silicosi. 33. BReinruckfs,erkHr.a:nkDuenrg. CMherdoimziantiksrcehbes, 3d4e2r, 1L95u6n.ge als 34. SAerpbk.eM, eGd..:, Z7:u1m14,S1c9h5n7e.eberger Lungenkrebs. Zbl. 35. JS.mIinthd,usRt.. MA.e:dL.,u1n6g:3C18a,n1c9e5r9i.n Coal-Miners. Brit. 36. aSnudndeKrminacna,idF, . JW. .F; .:DoNninceklelyl , pAo.isJo.n; inWg.estA, .MBo.Ab;. Arch. Indust. Health, 20:36, 1959. 37. JS.u; ndaenrdmaWn,esFt,. WBo.;b;KiNncicakide,l Jp. oFis.;onDinogn.neAll.yM, .AA.. Arch. Indust. Health, 16:480, 1957. TREATMENT OF PLUTONIUM DEPOSITION IN HUMANS WITH DTPA -- EFFECTIVENESS OF LONG-TERM ADMINISTRATION AND ORAL ADMINISTRATION* W. Daggett Norwood, M.D. Manager, Health Operation, Hanford Atomic Products Operation, operated by General Electric Company for the Atomic Energy Commission Richland, Washington solTuhblee repcloumtomnieunmded(Pmuax2im39u)minpetrhmeishsiubmleaanmbooudnyt oisf 0a.r0e4 nmeciecsrsoacruyriteo--li0m.6it /bigody(1)d.eRpoigsiitdioncotnotrothlismeexthteondts. Fbyorainfsatcatnocreo, falmloiwlliaobnlse tchoanncetnhteratcioomnspainrabalier aarlleowloawbeler Tcohnecreentrwaitlilonbse ofincmreaansyinogf pooutrenmtiaolst ftoorxiecxpchoesmuriecaltso. isnucihndisuosttorpye,sdwefiethnceth, eanexdpamneddiincginues.eHoefnscuechitmbaetceormiaelss vmeonsitenimt pmoertthanodt topohsasvibelethefosrafterseta, tbinegst, tahned imndoisvtidcuonal wwhhoichhaesxcaececdisdetnhteallmyaaxcimquuimredpearmdeispsoibsilteiolnimoift. Pu 239 boTrerdeatsmmealnlt,quhaenreti,tieosf offivePuem23p9lofyoeressowmheoyehaards ihndari cmaitneedpetnhtaatacienttircavaecniodusl(yDTadPmA)iniwstaesredmudciehthythleenemtroias-t eufrfiencatirvyeelaigmeinntatdioisncoovfePreud 23to9 (d2a)t.e for increasing the ofTthhee perfefescetnivtesnteusdsyowf aDs TmPaAde into eimlimprionvaetinkgnoPwuled2g39e rviioad thoef umrianney wmheonnthtrse.atImt ewntasisaelsxotenddireedcteodvertoawapred deleitmerimnaitnioinng otfhePueff2e3c9tivveinaestsheofurDinTePAandinfeicnecsrewashineng administered orally. Long-Term Administration of DTPA sitAionn eomfplaobyeoeutwh.4o hmaidcroaccucirdieentoafllyPurece2i3v9edsoamdeep3o0 mouosnlyt.hsInpirteiavliloyustlhye wdaasiltyreautreidnarwyithouDtpTuPt AofinPtruav2e3n9 wspaesciambeonutof66u5ridniesin(tTegarbalteioIn)s. Ipterwamsincountesidpeerred24a-dhvoiusr paberleiotdo cuanuletisosuselvyidceonncteinuoef tkreidantmeyenitrroivtaetrioann eoxrteontdheedr untoward effect appeared during the treatment. This D*Tr.heMuDrrTaPyAWfeoirnetrh,isGesitguydyPhtaearsmakcienudtliycalssu,pPp.lOie.dBobxy f4u3l0,inYocnokoerrsd,inNaetiwngYsoarmk.pRle. cHo.lleWctiilosnonawndasamssoissttinhgelipn ptheerfoirnmteerdprethtaetiobinoaossfayrsesoufltst.heG.mDan.yBsraomwpnlesa.nd staff wamouoludntseorfvePuth2e39daunadl ipnudripcaotsiengowf heelitmheirnaotrinngotathfearier wovaesr.aancheaxntegnediend epfefericotidv.eness of this agent when used T able I AEFDFMECINTIISVTEENREESDS DOTFPAINITNRAINVCERNEOAUSSINLGY URINAGRIYVEENXCFROERTIMOANNOYF MPOUN2T3H9 SW HEN TWreeaetmk eonft Doisne--GrDamTPs A Per Week ADvaerilayge ExUcrreitnioanry of ExpPruess2e3d9 as D iPseinr teMgirnautitoen s EExffpercetsivseednesass E%ffeocftiIvneinteiassl 21 21.6 661650 19020 Nopetrrieoadtmoefnt5 fworeeks 12 1131--1142 21.6 448915 7724 Nopetrrieoadtmoefn5t wfoereks 15 2267 22 449366 6764 4336 22 214960 2397 50 2 125 19 preAcveedriangge adnadilyfoellliomwiinnagtiotnheofabPouve23t9reaftomrenpteriwodass 12 disintegrations per minute in 24 hours. emEpxloceypeet fwoarsmgiivneonr 1chganogfeDs TasPAshoinwtrnaviennoTuasblyle, iIn, tthhee M1 agnuofnactTuhriunrgsdAayreaofMeeadcihcalweCeekntefor,r otnhreMeonsudcacyesasinvde wpeereikosd.sSoufchthpreeeriowdesekosf otrfeantomternetatwmeernet.alTtehrinsawteads wcoitnh- 610 SOCIAL AND LEGAL ASPECTS wtleomrke.nt above the loss of wages the longer he was off peTrpheitsractaessehiilsludsitsraabteislityhoown aansuibnjdeicvtiidvueabl adsiesliibneroartdeelyr toCianscereaNseo.th3e--sizAe o3f7-hyiesarm-ooldnettararyinmseattnlemweanst.injured wwhhielne hsitsanadrimngwatosostrculcoksebytoa agraslbowirloyn,mcoavuisnigngtrhaiimn taocsapr.inHaeroreucnediveadnda s5tr-cikme vheirstihceaal dlaacgeraaintisotnthaecrossidsethoef mmiadindeled oofnhhisisffoereeth. eTadh.eTlahceermataionnwwaasssrtuepnanierdedbautt trhee pTlhaenrte dwisepreensnaoryo.thXe-rraiynsjuorifestheexcsekputllfowr eareslingehgtatciovne. , ttuiosnionwaosf enthtiererlyighnteguaptipveer anardmr.emNaeiunreodlogsoic theexraemafitnear. cNaotiotrneaftomrenpat iwn.asTihnedicpaatetidenotthdeirdthnaont awnaolrgkeshicismneedxit otuursn naingdhtwahseseheandagaainmtihlde fhoellaodwaicnhge dabyu.tTwheasprneovwi apsaytimenpttomwaastics.eeEnxaamgaininatifoonurwdaasysagaafitnerntehgeatiavcec.idTehnte. aTphpeliesdu.turHesiswoernelyremcoomvepdla,inant dwaasdheoscicvaesiborniadlgefsrownetrael hreetaudrancehde two hwicohrk;waasndrewliehveend qbuyestaisopnierdin.asHteo hwahdy,nhoet garamve asnodmeupvpaegruebaccko.mEpxlaaimntisnaotfionsorweansesasgianinhnisegraitgivhet fthore ombajenctbiveeliefvienddinhges.coIut ldseeamndedshtooultdhebpehwysoirckiainng tbhuatt faoprprsoovmede froearsownorhkadandnotwadsonsoe asod.visHeed. wTahsefopramtiaelnlyt rweoturkrnededfortosevweorarkl hosiuxrsdbayust tahfetnerretphoerteadccoifdfebnetcaaunsde ocof mhpelaadinacinhge. oHf ehewaadsacsheee,n daizgzaiinnesst,heanfdollsoowreinngessdaoyf, thheealiunpgpewrelbl.acEkxaamndinartiigohnt reasrmul.ts Twheere lanceegraattiivoen owncaes atrgeaaitne.dHseymappptoarmeanttilcyaldlyid annodt inseteennd atgoaiwnorokn;ehewweeaks lloatweirn, gatthwishicvhisittimhee hwisasconnodtitiosenenwaasgauinnchfaonrgeadn.otFhoelr two weeks. It was then 24 days since the injury. The wpahtiicehnt hehadhadtakreenceihviesd vvaaccaattiioonn ipnayt.heHeinoteffreimred, fnoor Tcohmepmlaiannts,finaanldly threetuerxnaemd intoatiwoonrkwa3s0 adgaayisn anfetegrattivheis. ilnitjiugraytioanndagreaminastinethde actowmopraknyth, ebreecaafutesre. hHee dienmstaitnudteedd ceoarmnpinegnss,atainond tahbeocuotmspeavneyn retifmuseesd htois graacntut atlhelocslsaimof. peEriaocdh ittimseeetmhiesd ptahtaietnthewarseasleleyn bdeulrieinvgedthhee 3c0o-dualdy wicaolrlky aanbdle thaantd hewaasctnuoaltlycownsaindteerdedtoa.sHheavwinags pphoysst- atrpapuemaraetdic tnoeubreossiesv. eWrahl yretahseonns.diWd hhielenothtewpoarkti?enTthweraes bdeeinntg, tareacteodmpinanytheredpisrepseennstaartyivsehorretlmyaarfkteedr ththeaatcciit wgroouulpd hbaedggooondeiffohreandidunnuostuamlislsenwgothrko, fsitnicmeehwisitwhoorukt atielnotst-atnimdehaisccifdeellnotw. Twhoisrkewrsas aisntceorpmrpeatendy binytetrheestpian aRveosiednitnmgenlotstwtaims einrcaittheder atnhdan lethde teompdleolyibee'srawteelfalorest. tbiemceau. sTe hhee phaadtieanthewaadsinajlusoryewnchoicuhrargeeqduitroedmsiusstuwrinorgk. Amneontthbeyr cfaecrttoairn wphaircthiespltaoyeddelibaerpaatertlywpaesrpeentcraotueraugne ncleaciemssaarygailnosstt ttihmee cfoomrptahney pfuorrpoinsecoomfeesgtraebaltiesrhinthgana hisThreisguclaasreeialrlnuisntrgast.es how management action, work ignrouwporsktangdroaurdpss fionrtelrofsetretimwei,thantdhelitmigeadtiicoanl pmraacntaicgees mdiesanbt iloitfy tlheeadiinnjgurteodexecmespsliovyeemaonndetcarreyatgeaiunn. necessary Summary facItnorssutmhmatarhya,veI haavneegoautitvlieneindflcueerntcaeinonsoctihoe-edcoisnaobmleidc seumcphloyfaecet.orTsheintdeirsfceursesiownithhasthdeealitndwiivthiduwahly's arnedcohvoerwy fcrloemareranuoncdceursptaatniodninalg inmjuusryt , pwreicthedetheantyhoeufgfohrtt tthoatdoa anything about them. BASIC PRINCIPLES FOR PRECAUTIONARY LABELING E dward J. H ogan Vice-Chairman, Labels and Precautionary Information Committee, Manufacturing Chemists' Association, Inc;; Packaging Coordinator, Allied Chemical Corporation, New York, N. Y. asIta isreparnesehnotnaotirveanodf athepriMvilaenguefactotursipnegakChtoemyisotus,' Aufsascotcuiraitniogn, Crehgemaridsitns'g Aosnseociifatiiotsn acistivaitniesi.ncTohrepoMrataend n18a0tiocnoaml ptarnaidees eonrggaagneizdatiionnthceommpaonseudfacotfurme oarned thsaalne othfanch9e0mipcearls.cenTthoesfethecocmhpemaniiceasl parcocdouucnttionfocrapmacoirtye ofFtrhoem UintsitefdouSntdatiensg. in 1872, the MCA has been gcoronwcetrhneodf wthiteh cthheemmicaanly ipnrdoubsltermy.s Parcocmominpeanntyinamg othnge tchiaetsieonhaiss bpereonudthoefpirtosmcootniotrnibuotfiosnafsettyo, athned rtehceorAdssoof cthheembiceaslt minanuafial ctiunrdeursstriyn. thTishirsegaacrdh,iewvehmicehnits aismotnhge mofortehenointadbulsetriyn'svpierwoceosfsetsheanindheprreondtuhctasz.ards in many thaTtheofAsistosciamtieomn'bseirns'tereemstplionyeseasfetytogoiensclfuadrebetyhoonsde torbajnescptiovretsinagr,e hparnodmliontge,d ainndaunsiunmgbietrs opfrowdauycst,s.buTtheI swhiathll tdhiesculasbselaitngthoisf cthimemeicoanlslytothiantstrpuhcatsethocosenchearnnedd linIgn othr euesianrgly tdhaeyms ohfowthetoindduostsroy sbaofethly.the chemicals dinistnruibmubteedr aanndd etahceh thraaddesbeuesninlgontgheemstabwleisrheedli.mCituesd ctoommeprosuwndesre tshoatacscpuesctiofmicedintsotrutchteiounsse soefemtheed euxnisntiencg iensdsaursyt,riaalndchseumchicalws arwnienreg llaimbeitlesd astowethree ussterodngoenr HOGAN 611 aocfidcsouarnsde, atlhkeali1e9s,27anFdedeexrtarlemCeaupsotiicsonPso.isTonheArectwaenred, athenseumwbeerre cohfiesftlaytedirpeocitseodn toandthephlaabrmelaincyg oafctsh,oubsuet htoowldardpatchkeagheas.zarIdn omf oinsgt esctaiosens atnhdeyrelwieedresopleoliyntoend the word "POISON" to warn the user. useThoef eitxspapnrsoidounctosf btrhoeuginhdtursetcryogannitdiontheofbtrhoeadenneeedd fsoterpsmionrethcisomdpirreechteionnsivceamlaebeinlin1g9.34Onaendofcovtheeredeatrhlye uprnoifdourcmt gprroeucpasutiuonndareyr alabseelriinegs ooff vsoixlunptraordyucatgsreoer manednttshebeStwuregeenonthGeenmearanlufoafcttuhreerUs noitfedthSestaeteps.roTdhuecstes wagerreeemdiesnctosntsineruveedd bay vtheeryUunsietefudl SptautrepsoPseubulinctiHl etahlethy Sduercvtsicewihnich195h2adb,ecianustehespemceifaicntilmabee,lsbefoenr tdheevseeloppreod uprnodgerramthwe ereMcaonnusfiadcetruerdingmorCeheamppisrtosp' riaAtes.sociation's groAusp,chmeumliitciaplliepdroadnudctsg,rewespmecoiraellycominpletxh,e thoergnaeneidc fboyr faurstuhrevreystepcosnbdeuccatmede ebvyidethnte. TAhsissocwiaatsioenmpinhas1iz9e3d6 wofhiachprreinsuteltdedbionokdistittrliebduti"oAn tCoointsfidmeenmtiablerReexpeocurttivoens AMdaenquufaatceturLearb."elinTgh--isItsrepImorptorptaenrscueadtoedthme aCnyhemcoicmal pparongierasmtsooremtobaerxkpaunpdotnhosteheailrreaodwyn bewgaurnn.ing label ouWr oinrdldustWrya.rNIoIt gornelaytldyidacecsetalebrlaistehdedthcoemgpraonwietsh eoxf pthaenyd dtheveeirlopperodduinctniuomn eorfabwleell-nkenwowonnecsh.emMicaanlys, cbourt pasoractoimonpsletferloymneowthecronsceegrmnse,ntbsegoafn incdhuesmtriyc,al asmawneull foafctvuireew. Aonf dp--remcoasuttioimnaproyrtalanbteloinfga--ll,thforuosmandthse opfoiinnt dwiovrikdeurasl bceogmapnantioes,oplaerrgaeteanpdrocsemssaelsl, uasnidngmcilhlieomniscaolsf Tenhteirenlyeedforfeoirgna tcoomanpyrehoefnsthiveeirpproregvriaomus oefxepderuiceantcieosn. iinn t1h9e44saMfeChAancdolninsgideorfedchtehmeicparlosbwleams oabtviaousm. eEetairnlyg obefstitsmmethemodbetro erxeeaccuhtiveths.e Imt awnasindetchiededshotphatusitnhge cahnedmitchael pforormduactitosnwaosf bay m"LeaabneslsofanindstrPurcetcioanutiloabnealrsy, Information Committee" was accordingly authorized. calTlehde, LmAePt IfCoromthmeittfeires,t astimitehaosnsinMceaybe1e7n, p1o9p44u.laTrloy sinelseucrteedainbcrlouaddedvtihewoseofwitthhe chperombilceaml,, mthedeicmal,emlebgearls, rtehsaetarcdha,tea, dmthiinsisthraastivbee, eannda sacloesntibnauciknggrouanndds. aScitnivcee icnodmumstirtyteea.ndThademwinoisrtkratoofrs LoAf PhIealisth waenldl skanfeotwynproto gGruamidse tFhorroutghhe iPtsreppaurbaltiicoantioonf "WWaarrnniningg LLaabbeellss--foAr HfearrzeadrdtoousasCthheem"iLcaAlsP.I" MTahnisualm,"anisuanlo,wfrienqutheentrleyvireew stitoagne,thwisithyeaar. Fifth Revision scheduled for publica It might be assumed that, having agreed upon the wneoeudldfobreprseimcapultei.onAalrly olnabeelnineged, thdoe, wyroiutinwg ooufldlabsaeyls, is to mark a hazardous product POISON and add the idnov'solvaendd tdhoann'tst.haUt.nfortunately, the problem is more calWs hmaatyabree thhaermmfuealniinngas voafritehtey toefrmwsayuss.eAd? pCrohdemucit swhhoiuclhd mnoaty bethlraebaetelend ythoeursamlifee assoolenlye tbhyat imngaeystkioilnl balysoabthsoerpmtiaotnterthorfoudgehgreteh.e Hsokwin. sOhafllcowuersed,isttihnegrueisihs wbehtiwcheecnautshees cvyaapnoorsiso?r Wgahsatwrheiaclhly aisspahy"xpoiaitseosn"a?nTdhoenree ibsuttheaccduifrfaicteu.ltyThoefylamnguusatgeb.eSetaxtpermesesnetds imnustetrmbes btrhiaetf ostradtienmaeryntswhoreklpmeanvouidndaecrsctiadnendt.s,Nboutt oinflysumchusotcctuhre, fainrstinatiedrpsrheoteurl.d Innotthbeecadseelayoefdtrwadhei-lenasmoemdeocnheemhiucnatlss otor pthroeprdieotcatroyr cwohmopomunayds,bewhaastkeisd otuor trreesaptonpseibrsiolintys injured by them? folAloswainrgesuplrtinocfipthleessewaenrde madanoyptesdim. ilTahreqsueesptiroinncs,iptlhees aLrAePsIetMfoanrtuhali.n detail in and comprise Part I of the lem1. Eaancdh mchuesmt icbael tprreoadteudct inpdreivseidnutsallay diinstinthcte plrigohbt ohfaziatrsdsowonf achparroacdtuecritsticcasn.noCtonscalfueslyionbse rdergaawrdninegiththeer fisrofmormtheed porropbyertainesaloogfiesthebasmedateurpiaolns cfrhoemmicwalhiscthrucit pturroep.erMtieixstuthreast ovfarytwion okrindmoorre dcehgermeeicafrlosmmathyosheavoef tmhiextuinredsivisdhuoaulldcobme pboanseendts;onantyhewparronpinegrtielsaboefl tfhoer fpirnoipsheerdtiepsroadnudct.shIomupldurintioets bmeayovceornlotroikbeudte. hazardous bri2e.f,Aallccusrtaatteem, aenndts exopnreswseadrniinngsimlapblee,lseassihlyouuldndebre stood terms. an3d. tPoretchaeuteioxnteanryt nlaebceeslisnagry.shTohueld labneguusaegde osnhloyulwdhebne pofraactipcraold, ucntotalobnaes,edbutupdoirnecttehde toiwnhaerdrenthte parvoopideartnicees ostforhagazearadss mreasyultrienagsonfraobmly sbuechanutiscei,pahtaendd. liTngh,e aunsde othfewuasrenionfgulnanbeeclesssfaorry rweloartdivselwyillhadremvleelsosp paroddiusrcetgsarodr ffoairlulraebetlos gainved addeefqeuatatethneoirticpeuropfohseazaarsdss.urely as will gu4a.geOtno lianbdeiclsatoeftdhieffsearmenet hparzoadrudcstsanudnisfaomrmeidtyegirneelsanof huanzdaerrdstainsdimngostthdroeusigrhablestainndarodridzeartiotno. gain greater sid5e.reTdheforfoilnlocwluisnigonsuobnjecat wmaranttienrg slhaboeull:d (ab)e nacmone ohfazaprrdo--duDcAt;NG(bE) Rs!i,gnaWl AwRoNrdINdGe!s,ignaotringCAdeUgTreIeONo!f (mc)eaAsuffriersmactoivveersintagteamcteinotnsoftohabzeardfosl;lo(wd)edproecraauvtiooindaerdy; a(ed)viIsnasbtlreu.ct(iNonOsTEin: cuansedeorfsocmonetalcatwosranextipdoostuerseawreherree qtiuoinrsedforwthheenhathnedliwnogrdand"PsOtoIrSaOgeNo"f icsonutsaeidn.e)rsInshstoruulcd iaslsoinfboermcaotniosinderreeldatifnogr tionclcuhsaiorancteornistitchse olfabtehl.e Tcohnis tainer as well as those of its contents.* sku6.llTahned icnrcolsussbioonnesofonthae lwaboerld s"hPouOlIdSObeN"limanitdedthtoe those cases where the product is a poison according 612 SOCIAL AND LEGAL ASPECTS ptoresacrdibeefidnitbey tloaxwi.ciWty hsetnanudsaerdd, othriswlheegreendsuschhouulsde bies huPnadrrtesdIIilalnudstrIaItIivoef tlhaebeLlsAPsuIcMh aansuatlhceonotanien ssheovwerna.l innotadtadkietiotnhetoplatchee oolthtehre lwaboerdl swDarAnNinGgsERa!n,dWsAhoRuNld aTmhopslees iinnclPuadretd IaIreagreeneforarllyindfoursttrhioalsecphreomdiuccatlss. mEoxst IthNeGr!e,laatnivde CdeAgUreTeIOofNh!,azwarhdic.fh are designed to show iambprooratdanrtancgoemomferhcaizaallryd,s.anTdh,easlaabewlshionleP, athrteyIIItakceovienr sh7o.ulAd nnoontdebsecriupsteivde acsodtehedeosinglynatiidoenntoifrictartaidoen noafmae sthecetiomnajwoaristyadodfedpefsotilcloidweisngsotlhde ipnaslsaarggee ovfotlhume eF.edTehraisl hshaozwarnd,outshechleambeilcals.hoIufldthceleacrolmy psletatete ntahme e tyipse nootf ITnhseectliactitdeer, rFeuqnugiriecsidea,deaqnudateRowdaernntiicnigdelaAbeclts ifnor19th47is. ch8e.mWicaalr--nien.gg.,st"aCteomrreonstivseshAocuildd",b"eLgeraodupCeodmtpooguenthde"r. ihmavpeortthaentingfroorumpaloafpcphroemvaicl aolsf, tahnedUtnhietedMSCtAateslabDeels pinrinatepdroimn ineaesnitlylolecgaitbiolen toynpethwehilcahbeils ainndcoshnotrualsdt bbye . pInatretrmperenttatoiofnA1g8r,icRueltvuisreionan1d. are consistent with its ttyerpoognratphhey,lalbaeyl.ouTt,heorlacboellorshwouitlhd obteheafrfipxerdintfeirdmlmy atto expHeocwteds,utchceessLfAulPIisptrhinecipLlAesPIhaPvreogthraemb?roAasd msuapypobret anIdn inacacocrodnasnpciecuwouisthpltahcee opnrintchieplceosntjauisnters.tated the o90f MpeCrA cemnetmobefrst,hewhUo,.S.aspsrotadtuedctioenarlioefr, irnedpurestsreinalt "uDsuAalNGwEaRrn!i"n,g"WlaAbeRl NinINclGud"e, so:r ("aC) AaU"TsIigOnNal""--wtoorgdi--ve- cahnedmiocaults. oIfn thfaect,Ascshoecmiaitcioaln, mfaunlluyfacstuuprperosr,tebdoththeisne aa gsteanteemrael nitndoifcahtiaoznardof otrhehaszeavredrsi--tysuocfh haaszar"dV;ap(ob)r panridnciisplessu.ppTohretedveeryxefratsctathpaetrsusuacshivea fporrcoegraumponextishtes EAxbtsroermbeedly THharozuargdhouSs"k,in""C; a(uc)sepsreBcuaruntsio,"naoryr "mReaapsiudrleys mlabaenluinfagc.tuTrhere lwahttoer mknigohwts oththaet,rwsihsoeuldneghleecbt epcraolpleedr --hesautchanads o"Dpeon nfoltamber,e"atohre "vAapvoorid," c"oKneteapct awwaityh frsokmin itnoadceoquuratteblyecaluasbeeleodf pcrlaoidmuecdts, inthjueryopbpyosionnge coofunhseisl ainndcaseeyeosf";acacnidden(td, )a,s w"Ihnerecasaepopfrocporniatatcet, iminmstreudciatitoenlys swimouilldar scuormelpyetictiivtee pthroeduwctasr.ning statement used on afltuteshntisoknin."or eyes for 15 minutes; for eyes get medical CoWmimthiitnteemionnth19s44a,ftietrs tchheaiormrgaannizwaatisonasokfedthteo LsAerPveI maUysirnegad:these or similar statements, a typical label saesquaednvtilsyorbetcoamtehetheStfaitrest ooff sCevaelirfaolrnstiaat,eswthoicrhegusluabte DANGER! HAZAARNDILOIUNSE LIQUID AND VAPOR RAPIDLY ABSORBED THROUGH tBheesidpersecCaaultiifoonrnariay, tlhabeeleinngsuinogf yheaazrasrdhoauvse csheeemn icsaimls. ilar regulations or laws adopted by Connecticut, SKIN Oregon, Hawaii, Illinois, Texas, New Jersey, New ADvoonidotbgreeatthiningeyevsa,poonr. skin, on clothing. Yupoorkn SthtaeteMaCnAd pNreiwnciYploersk. City. All have been based IUnsecoansely owfitchonatdaecqt,uaitmemveednitailtaetliyon.remove all contaminated clothing, including shoes, and InsReecftiecriednec,e Fhuansgicaildreea,dyandbeeRnodmenatdiecidteo Athcet, Faneddertaol the fact that LAPI labels comply with the regula fleluassht 1s5kinmionruteeyse;sgwetithmepdliecnatlyaottfenwtaiotenr. fWorasaht clothing before re-use. tioAnst misesueteidngpsuorfsuthaentIntoterint.ational Labor Organization, POISON hareyld laibnelGinegnesvyas,teSmwiwtzaesrlaenndd, otrhseed MaCndA'smpurcehcauotfioints *Author's Note: The Manufacturing Chemists' Associa cwoidnetenbtasaisd.opted for ultimate use by ILO on a world Atiovennuhea,sN.aWva.,ilaWbaleshiantgtoints 9,ofDfi.cCe,., a1t82n5omCinoanlneccotsitc,uat GoAvercnommemnittatleeLaobforthOeffiIcniatelsr,nawtihoicnhal coAnsssiostcsiatoiof nU.oSf. sthereiepsroopferitnidesivaidnudalessCehnetimalicianlfoSramfeattyionDafotar sSahfeeehtsanodn aisntdratoCrsa,nahdaisandesvtaetleo,pepdroavin"Sciuagl,geastnedd DferdaefrtalfoardmUnini alinndg Raencdomusmeenodf e1d9Pcrhaecmticiceaslso,nMthaneuuasles aonndShtaannddalirndgs ffoorrmUsReu, leHsananddlinRg,egaunldatioSntosrargeelatoinf gCtoonttahineerLsabHeolilndg goefnsepreaclifipcreccoanutatiionnesrs,foarndhaanndloinugtlinaendofstroercaogme moefncdeerd iEnmgplSouybesetsa.n"ceTs hHisarmdrfauftl taodhtehreesSatfoetyLAanPdI Hpreianlctihpleosf tTahinesecladsasteas wofillcosenrtaveinearssexinceltlheentMgCuiAdesLAinP1thMe adneuvaell. ianndNewwasJetrhseeyfoanunddNateiown Yfoorrk tShteatecuarnrdenCt itrye.gulations aonpdmesntotraogfeasptpaltiecmabelnets.phrases for container handling indInusttrhyispahritgichulylarrleyg,ualaretedsubejreac--tewd hteonmaalnl yofresutsr,icatinvde fAuthor's Note: The word "POISON" has been used ilcaawlsinadnudstrreyguthlaattiointss--aditeqiusattoe tlahbeelcirnegdiptraocftitchees cbheegman iinlldidsecfriinmeidn.atFeolyr ilnabtehleinpgasptu, rapnodseists tmheeaMniCngA hMasabneueanl laastioanvoolfunrteacreyntpryoegarrasmhaasndbetehnat inthesulpabpeolritngoflegthise irnegcoesgtnioizne,s ipnohiasloantiinogns, abnyd tharbeseormptoiodnes thorfouegnhtrys--kivni--z., industry's principles rather than controverting them. Further evidence of the LAPI Committee's in tbouxticliitmy ithsasusbeeeonf dtheme ownostrrdatetod, theoitsheercabsyes hwuhmearen tehxe sfltuaennticaellyis tihdeenftaicctalthawtitdhefitnhiatitonsoffoirts"PmOaISnOuaNl" wsuebre pdeerfiineendceliomritlsa.boratory animals tests, to exceed certain wsercittitceinde inAtcot athned rheagvuelatailosnos buenendersubthsetituFteedderianl tIhne KLEIN 613 IfonrtemrsetratdeefCinoimtiomnerocfe "CColmasms iBss.ioPnoiRsoengsu."latAiognasin,foLr AthPeI hoafsthbeeewnoridnst"rfulmamemntaabl lei"n boybtIaCinCingandtheothaecrcepptuabnlciec a"ginefnlcaimesmaabsle.l"essItslikreelpyutatotionbe hamsisuexndteenrdsteododsothfaanr tMhaatnufinactu1r9e5r3s, twhehicAhssiosciMatiCoAn'sofBriBtirsihtishcouCnhteermpiacratl, sthenetLrAePpIrepserongtartaivmesantdo stuhbisseqcuoeunntltyryadsoolpetleyd toonestpuadry allTelhinisg pitr.ogram is receiving additional impetus from oouthserintratdheeirasscoocoiapteiorantsi,onw.hAicsh ahlarveaedbyeeinndmicoasttedg,entehre LchAemPIicaolsb.jeWctihviele istheprpinricnicpiapllleys aairme egdeneartalliyndaucscteripatl adbelteail tofoarlldigffreoruepnst, stehgemirenatsp.plAicatcioonmmmitatyee voarfy thine Cprheepmariceadl aSpmeocidaelltielsawMfaonrutfhaectularebreslinAgssoofcihaotiuosnehhoalds padroddituicotns. toDisrmecatlilonhsoufsoerhouslde paareckuagsueasllayndanmiamypcoorntvaenyt pinrfeocramutaitoinoanryfosrtatpermoepnetrs. uSsiemiwlahrliych, thsuepAplmemereicnatsn tPhee tcraoulteiuomnarIynsltaitbuetles rfeocrenptleytropluebulmishepdroadumctasnuaasl doifstpinrcet fprroinmcippleetsr.ochemicals. Both associations support LAPI anTdheunciofmormmonlaabimelinofg alolfthtehsee ghroazuaprsdoisusthesuabdsetqanucaetes wfreheichflotwheyofprcoodmumcee.rcUe naifnodrmiimtypoirstaenstsenintialedfuocratitnhge pinegosp. lTe hteo puunbdleicrsmtanudst tbheelesdigntoifirceacnocgeniozfe ltahbaetl cwheamrni qcaulirperocdaurcetsinmahya,nodnlinogc,cajsuiosnt , abse ehxapzearrideonucse atneadchrees utosolsthaatndcarwe ithin ehlaecntdrilcinalg aisndnecmeesscahraynicwailthdeevdicgeesd. cUhnelmikiecaltshe wlailtltera, lwwahyicsh rseeqlduoirme csaormrye wparrencinagutiloanbaelrsy, lmabineelidngb,ybevciasuusael tihnespirecptrioonp.erties can seldom be deter preIncauctoinocnlaursyionla,bIelisnhgoupldroglirkaemtobaesemdphuapsoizne tthheatprainny cciipalteiosnsectofuolrdth nboyt tbhee McoannsiudfearcetdurienxgpeCrhimemenistat'ls. ATsshoe ctiomnec-epprtovoennwahnicdh ascuccehptaedpriongrsaimmilwaarspbraosgerdamhsasinbeteern ntaaktieonnaolluyt. iWnsiutrhanscuechona tphreogfruatmureyoouf yhoavuer pnrootduocntlsy, bfuuntdaymouenthaalveoblpirgoavtiiodnedtoawnaercnesosfartyheadhjeuanltcht hianzatrhdes pinrvoodluvcetds. in the use of either new or established I thank you! THE CARDIAC CASE IN WORKMEN'S COMPENSATION Irvin K lein , M.D. Medical Director, Workmen's Compensation Board, State of New York thiIrtteiesntmhy Ignrteeartnaptlieoansaulre Ctoongbreesasbleonto Oacdcdurpesastiotnhaisl nHoeanltahti.oIntalisbosiugnndifairciaenst, tahnadt tcoogmetmhoern wperobhlaevmessokungohwt r3e0myeedaierss. iInt disiffaeprepnatrecnotunthtraitesthoifs tihse thweoroldnlyforsoouvnedr mofetahdodditiboynawl hsicighniwficeanccaen tshoalvte wtheesaereprothbulesmasb. leIt tios smetattearsgomoady bexeamdipspleoseodf otfh.e way in which other casTehiisn awfoterrknmoeonn's wcoemapreensattoionc.onTsoidemr ertehley cdaisrmdiiascs ittalewnitthantdhe inwteavnetioonf othfethhisandorgiasniuznawtioonr.thyA osfearthche ianntdo itmhepocratuasnets. Tanhdereresiusltsa icnontthiinsuianrgeaanisd ngecroeswsianryg iinntetrheestcoiunrsethoef ecmarpdliooyvmasecnutl.aRr eecpenistolydegsredaut rainttgentaionnd hcaassesbweehnichpahiadvetocomthee beinfocrreeatshinegwnorukmmbeenr's ocfomthpeesne sNaetiwonYobrokarSdtsatefoforr ethvealuyaetairosn19a4n7dtoad19ju57dicthateiofnig.urIens hthaevefirrsitsesnix fmroomnth1s6o7f c1o96m0puenpsatoted150cacsaessestowe5re45c.loFseodr wwiitthhdoruatwaawl aorfdcflaoirmm, aannyd rfeaailsuornes t(ofamilaukree otoutparopsercoupteer, cbaeseen atfhteer ctoriraoln).arTy haertemroiesst frreesquulteinngt iinnvoplvoestmocecnltushivaes anIgtinias, nfaoitlunreec, epsusalsrey iarrtegthuilsarittiimese, atondreivnifeawrcttiohne. var iiosuist snkeicllesssianrvyoltvoedreviniewthethediangeneodstifcorpprorcoepdeurrehsi,stnooryr and record keeping. We can safely assume that the tthraeisnee. dThpehreysriceimanainiss, thfuelrleyforaew, aornelyotfhethceonsniedeedratifoonr owfortkheloraedlatainodnshthipe opfrotpheer praethhaobloilgitiactiopnrocoefssthtoe pthae itnientth.eItcliosssuurgegeosftead cthoarotntahrey evxeascsetlmaencdhatnhices riensvuolltvaendt mmyuostcabrdeiafluritnhfearrctcioonncedaered nthoatt ftuhlely sculnerdoetrisctopordo.cesIst bpelagyinssafaliarrlgyeeapralryt iinn atdhueltolcicfeurarenndcethiisn, uinndduosutrbyt.edly, is Iht irheads bfoerenhitsheabpihliitlioessopahloyngthawtiththealwl oorfkinhgis mdaisn ainbciluimtiebse,nwt hueptohner thmeanpihfeyssticoiarn htioddbeen.thIet ifsirstthetorefroerce oogfnitzheis thasis winell.inIdtusatrpyp.eaOrsthetors msheouthldat bneo codgenfeiznasenst caanny bdeegsereteupofonscltehreostihsotuhgehtcltihnaictailn eandgivreensucltasewwouitlhd hthaivse tyopcecuorrfedreainsonaninyg elveeandts. nWoewhmeruesst, rseicnocgenigzeenetrhaalt itzoatbioenpsrehpaavreed ltiottlteakevaaluneatitnitudtheiswhairceha.apIpt eairss breeast seoanchablceasteo oonrdiintsaryowannalmyseirsitsa.ndRebceogrneiatdioyn totharetviewwe dporecnloutdehauvse farofmull derxapwlainngatiaoncoantcltuhsiisonti.me should not proIctesiss iims ptohretandtomtoinaknetep faicntomr iwndhenthatthethecarldegiaacl cbaesceominesinidnuvsotlrvyedis idniscauscsaesde. Ttoooaofptoenintthebepyhoynsdicihains mofedanicaaldvsopchaetree.inAtthethpartocpeoeidnint ghsefoarttwaihnischthhee isstantuost trained, for which he is obviously ill prepared and MAXIMUM ALLOWABLE CONCENTRATIONS dinailystawtionrgk wMitAhoCuteiinthteerrv)alspe(rwfohricmhinagre pnhoytscicoanlsidweorerdk w(ohric1h0:1re; qluoiwreesr avvoeluramgee cmoiunludtebelucnognsvidoeluremde oonfly12fo:1r ewnatsireelvyidesnetdetnhtaatrya wwoorrkk)m. anFroambsortbhsis3.4caglcu(loartio2n.8 gi)t o85f0trmicghl(o7r0e0thmylge)neofintricehilgohrtacheotiucrsa,cidmoadnifdiesintiot 1in89to7 mgIt(1is41d2ifmficgu)ltoftotrsicayhlohroewthagnreoal.t is the pharmacologic edfufeecttooftdhaeilyfacatdmthiantistirtatdiooens onfo3t gococfutrricinhlosruecthhydleonsees, iisntemreeddicpalerpraccatsiece.inIn tchaesespasotfyeaarnsgi1naml pweacstoaridsmionr nBeeufroarleghiaandn,.throigweemveinr,i,wefocuarn tsiumpepsosea adhayypnmoatixcimefufemc.t emsepdeciaiaryllyprifodwuecttainkethinetomcetoanbsoidliesrmatioofntrtihcahtlotrheethyinletenre icshlochrelothryallhenyedractoer.reTsphoendass,ceacrtcaoinrdeidngdatoilythdeosAemoefrictarin tMheACc,utrore4n.t3 ghyopfncohtiocradlhoysedraiste.1I-2t isg,waenlldkniot wins tahlsaot kvneroywnrartehaatndchirsonsiicmiilnatroxtoicacthioronniwc itihntocxhilcoartaiol niswnitoht tricIthloisreathlsyolepnoes.sible to see to the effect of trichlor eetthhaynleonle, wanhdic,hinisouthr eoppirniinocnip, aitl ismpertiamboalriitley orefsptroicnhsilbolre fthoratthpehasrymmapcotolomgsicoflitienrtaotxuirceatdioone.s Onowtinogftetno mtheentfiaocnt Nthaisrcosusibsstiasncaet,tawineecdanbycotmhipsarseubisttawnicthe tarfitberroma edthoasenool.f f3o.5rm-5.s6 1g.9ign oaf mtraicnhlworeeitghhainnogl 7d0aiklyg.. In our case there thaIt ththinekAtmhaetrictahneseMAcoCnsiisderraatthioenrstoroesuhlitghi.n Itfhiet fwaacst ctoreadteecdlafrreomthaetxpaenriimmaelnstsawreithnoatnismuiatlasb, liet iisn ntercicehsslaorry- eluthnyglsenaendcahseasvebeecnatuisreelythedyiffhearveentgwreaayts doefsamtuertaatbioolnizs inbgy triTchhleoredtohsyelenreeq. uired by Swedish authors, 50 mg of otrnilcyhlotoractheeticSoavciiedt MinAuCr--inteh,atcoirsr,e9sppopnmds atbhoeourtet5i0c.ally ereFdromonloyurtripcrhelvoiroaucsetiecxpaecriidmeinnts,smwahlelerre pweercecnotnasgide, o16f tpreicrhlcoernetthwylaesnefouinndaitrha(tupintolowabeoructon4c0e0nt/riagtiopnesr laictiedr--inthamtg itso, t7r5ichploprmet)hytlhenee riantiofig oifn t1ric1holofraaciertiics ainbgoucto1n:c2e.nTtrhaitsiornatioof wtraischdleocrreetahsyilnegnew. itShevtehrealinocbresaesr voautriornescefnrot mexpprearcimticeentsberaersuwltistnetshsattothtehisratfiaoct.isFrtohme othreatticiatlliys n1o:1t p(oSsosuibielek-tVolagcivheovmi,orBeaarctocnuiriaetke).dirIectthioinnks pforarcptircaaclticwe,ordkueantdo tthheusgrweaet cdainfficcuolnticelsudoeccuthrraitngthiins ratOion ltihese wbaisthisinofthleitermaetunrteiondeadta vtahluaets a1:g1reaotr p1a:r2t. oaflowngo-rtkimineg wpoerokpalet 5h0avmeg ohrea1l0th0 mdgistoufrbtraincchelosracaeftteicr sapciodndinwiutrhin1e00petrol2i0te0r fiwgeosfeetritchhaltoreitthywloeunled incorarier. Tofhitsriccholnocreenthtraantioolnininuariinrec.orresponds with 100-200 fig vaFluoers tihnethpeurmpoosset iomfpsoorltvainntginthdeustqruiaelstpioonisoonfs MthAerCe omuagdhet otbosebrveataiovnasilaibnlepraactgicreea. tItnuismablesor onfececsasraerfyulltyo imnveteasbtioglaistem,,inanldabeolriamtoinryatieoxnpeorfimtehnetsse, tshuebstaabnscoersp.tiFoonr, macetudaicllayl tahbisnokribnegd idtosies. aEccxeppetraimbleentsto wciothnsidaenrimtahles daruecesduictahbelmeicoanllysufbosrtanthcees.orientation of newly intro SCIENTIFIC BASIS FOR THE ESTABLISHMENT OF TOLERABLE LIMITS ADOPTED IN THE UNITED STATES FOR THE PRINCIPAL INDUSTRIAL TOXINS Ch a rles R. W illia m s, P h .D. Assistant Vice President, Liberty Mutual Insurance Company, Boston, Massachusetts limInits)theforUinnihteadlatSiotantesa,rehydgeievnelicopestdanfdoarrdtshe(topluerrpaobslee etonxciec tmo aatecrcieaplst.abTlehuvsaluwees ffionrd esxupcohsutreersmstoaspo"tMenatixail osufrepsrotvoidtionxgicgmuiadteesriatols bine uinsdeudstfroyr. cTohnetsreollgiunigdeesxparoe mthuembrAoaldloewstabulesagCe;on"cMenatxraimtioanl ,"AcwcehpictahblceerCtaoinnclyenthraas dmeapteenridaelsntthoenrethaerebasleicveplshiloofsoepxhpyostuhraet wfohricmhocstansucbhe Stiotann,"darwdhsichAshsoasciabtieoenn Zu3ti7lizeCdombmy itttheee A(1m);eriacnadn ttioolnersatteod twhiisthpohuitloasdovpehryseaereffetcht.osTehwe hpicrihncairpealapexpclieepd "ATmherreischaonld CLonimfeirtencVealuoesf," GwovhiecrhnmiesntaulsedIndbuystrtihael tkonocwanrcionfotgheenipcroacnedssesseonfsitciazricnignomgeantiecriitaylsa. nSdoselintstliteizais iHmypgliiecnaitsitosn--(2)n.aAmlellyo,f tthheaste ttheersmesvhaaluveesthaeresaamlloewbaabsliec ktinoonwnthactartchineogteenndicenacnydissetnositcizoinnsgidemr attehraitalslevsehlosulodf ofirneaclcinepetabbeltewoeernthtaotxitchearnedisnoanltiomxiict.wAhsicah mdeantotetersoaf tbheenk,epist taos dcelvoeseloptoinzfeorromaatsiopnoswsihbilceh. Tcahne pprorovbidleema, cfaocntn, otthaetiounses.rs Tohf ethepsreobtelermms risareolnyeacocfepstemthaentiimcsp.lieInd vwahliidch bcaasnisbfeortoleesrtaatbeldishiningthelevinedlsusotrfiatloxeincvimroantmereianlts. A19n4n9uathl e CCoonmgrmesistteoenonOcCchuepmatiicoanlalAgHenetasltaht t(hUeni9tethd TERMINOLOGY Swtaastesm) urcehcommmoreenddeedsctrhipattivteheoftetrhme "aHctyugailenuictilGizuaitdioen" In order to avoid confusion it must be pointed out that there are differences in terminology with refer oInfdtuhsetrianlumHbyegrsie.neIn ASsseopcteiamtiboenr, be1g95a5n, pthuebliAshminegricaitns WILLIAMS 989 m"HenydgeiednicMGaxuiimdeumSerAietsm"osupshinegric thCe ontecremntra"tiRoencom(8 "hHouyrgsi)e."nicInSta1n9d5a6rdsSmfoyrthDa(i3l)y pInrohpaolasteidon.t"heFoursesomoef atinmcee thoef wtrhieter c(o4)ncheapst beoefn u"Hrgyinggienthice gSetnaenrdaal radc"cepotr "mHoyregieanccicuraGteulyidet,h"e saicntcueal thpeusreposteermofs theexparepspslicmatuiocnh of such criteria in the occupational health field. ORGANIZATIONS guIidnestheis Ucnaritreiedd Sotantesbythegroesutpasbliosfhmceonmt poeftenhtygiinendiic vuitdiluizailnsg oapvearialtaibnlge wteicthhninicaelxiinstfionrgmaotrigoann.izTathioensAmanerd irceapnresSentatinndgardAsmeAriscsaonciaitniodnu,strya, phraisvabteee' norsgpaonnizsoatriionng dfieevldelospinmceent19o4f1,stcahnidefalrydsthirnoutghhe oitcscuZp3a7tioCnoaml mheitatleteh. Tpuhrepsoese"Aamserwicealnl Sastangdeanredrsa"l inpchlyusdiceal-thcheemscicoaple aanndd taonxdicspamroppleirntgiesa,n"dMaanxailmytailcaAl cmceeptthaobdles Canodncerenfterraetniocne,s". Sliisnhceed,thaenidr stthaert C1o9msmucithteestaisndcaordnstinhuaivneg bteoenbepuebx tCreommemlyitteaectivoepeirnatetsheisfiseeldt . foTrhthe binasitsheoninwtrhoidcuhcttohriys sfotalltoewmse:nt provided with all of their standards, as "CTohneceMntreaatnioinng" o(f1)Maximal Acceptable levIetlsisofgecnoenraclelnytrarteicoongnoizfedatmthoastphtehreicre coarne wtaimthionaunt tskntoowwnhiiclhl aeffpeecrtssonormdaiyscboemfeoxrpto. seInd vuinecwonotafmtihneateimd pariarctiincambiolistty inodfusmtraiianltaeinnvinirg oabnlmeenctosn, cietntirsatinoencsessoafryattmo oesspthaebrliicsh coacnctaempt iTnhaenstes ecnocnocuennttrearteidonsin inindthuesmtrisaellveospedraotionnost. rreepprreesseenntt tahesccaolneceonftrarteiloantisveof tocxoinctiatym;intahnetys bexelpoewrienwcheidchbyilalnyefbfeucttshyapreersuunscliekpetliybletoindbie vidTuhaelss.e concentrations are usually based ufoplolonwidnagtaproobcetadiunreeds: by one or more of the ((21)) LLaabboorraattoorryy tteessttss uonsinagnihmuamlsan subjects (3) Etinovnisroinnmpelnantatls and medical investiga thaAt ctohmemeoxnpefreiamtuernetalof etxhpeosseurperocsehdaullrescoris rsehsopuolnddb.etotakthene innotormcaolnswidoerrkatiopnattaelsron.inTthhies atipopnlicvaatluioens. of maximal acceptable concentra meTnhtreoef tchreitseericaonhcaevnetrgatoivoenrsn:ed the establish ((21)) FOurngacntiiocnaolr ortehaecrtiotinsssuewchhiacnhgeshave no bdiustcecrnauibslee iumnptoaiwrmaredntse,ffescutcshonas hiena-cltoh oacrdciidneantitosns and increased proneness to I(3n) tDhiossceomcafsoerst ionr wadhviecrhsethseenscoornyceenfftreacttisons hchaavnegebse,enit eisstalbolgiischaeldtoonastshuembeastihsatofreopregaatneidc exposure to concentrations significantly in eaxbclyesswoofuldthepraocdcuecpetabinlejurcyo.ncWenhternatiothne plreovbel htiaosnableecnhaensgtaebloisrheddiscoonmftohret, biatsisis olfogaicaful ntco gasresuamtlye etxhcaetedeinxgpotshuereactcoeptcaobnlceecnotrnactieonntsratnioont wHoenuclde nitotispriomdpuocertamnattetoriaullnydienrjsutarinodustheeffeccrtsi. atebrliea cuopnocnenwtrahtiicohn ahnays bsuecehn emsataxbilmisahleda.ccept ceTnthraotuiognh itshetopumrpinoisme izoef thheealatchcehpatzaabrldes,coints iemngmineedeiaritnegusperoicsedfourregsuitdoanpcreevienntesotabbjelicsthioinng atebrliealscofnrocmentbraetiinognsproefsetnotxiicn othrenaoixriooufswmorak panlaacleyss.es Cwoimthpartihsoosne ocofnctehnetrarteiosnulstsinodficaateisr aecxcteenptt,ablaendconudrigtieonncsy orofothcoernwtriosle tmheeasnuereeds., Sbyamcpolminpgetaenndt apnearslyosninseslhuosuilndg baencaacrrcieepdtaobulet mofetehxopdoswurhei.ch will provide a reliable measure coAnciernatnraatliyosness ionf csouncjhuncattimonoswphiethricaccceopnttaabmle itnioannstssearsveareasenacmouenatseurreed oifn eixnpdoussutrriea--l noopteraas aDimagenaonssesosfhdoiualgdnobseisbaosfedococnupaaticoonnasliddeirsaetaisoen. ophf yaslilcaflacetxoarsmiinnactliuodninags wreeslulltass ooff acliirnaicnaallyasnesd, mtheeanbsodoyf, asasnedssinag kanmowoulendtsgeofofmatotexriicaollsogiinc effIencts tohfe thaeppmliactaetriioanls ionf qutheestiosnta.ndards, it sh(o1u)ldThbee kaecpcetpitnabmleincdonthceant:trations serve as (2) Tsthaenydarsdersveofagsooedngpinraecetriicneg. guides. De staiginninagnd aollpercaotinocnensthraotuioldnsaimbelaotwmatihne (3) Tachceeyptsahboleuldmabxeimapupmli.ed and interpreted buyndecrosmtapnedtienngt oinfdtihveidubaalssis wainthd laimfiutall stitoannsdaorfdthheasinbfeoernmadteiovnelofproemd. which the (4) Ictonissidaedrevdisedto thbeat gtuhiedsees sttoawndaardrdsgoaorde iansdluesgtarliarlehqyugirieemneenatns.d are not intended (5) Tpohseurelevteols aaresinagpleplicsaubblsetanocnel.y Itno tehxe cmaasey obfe einxcproesausreed toor mdeicxrteuarseesd,,tahnedefcfoenct striotulsatisohno.uld be based on the specific triTalheHyAgmieenriisctasnbeCgoannfeirtesncweorokf iGn otvheernsmtaenndtaarldsIndfiuelsd winith194v7a.luTehse, ywphuicbhlisthheaynncuaalllly"tharelisshtooldf thliemmitsa.t"erTiahlse, vcoalmuemsitwteheichof aqreuagliifvieend reexppreerstesntinthetheconoccecnuspuastioofnaal dhaetaeltheacfhieldy.eaTr.heTyhearme orsetvrieewceendt panudblisbhroeduglhistt udpatetdo t1o9x5i9c (d2u) sctso,ntfauimnsesv, aaluneds mfoirsts1;6911gamseisnearnadl dvuasptosr;s;an7d1 aphilliosstopohfy 2o1f sthoi-scalgleroduptenistastievte fovrathlueisn. pTahraegrbaapshics preceding its listing of values: "Threshold Limit Values for 1959" (2) inTthhreeschoonldtrollimoiftsheshaoltuhldhabzearudssedanads sghuoiudelds 990 MAXIMUM ALLOWABLE CONCENTRATIONS nanodt dbaengreergoaurdsecdonacsenftirnaetiolnins.esThbeeytwreeepnresseanfet conditions under which it is believed that BASES FOR HTYHGEIEENSITCABGLUIISDHEMSENT OF dnaeyarlyafatellr wdoaryk,erws imthaoyutbeardevpeerasetedelyffeecxt.poTsehde, values listed refer to time weighted average inTthhee eUsntaibtelidshSmtaetnets oisf nbuasmedberpsrimfoarr"iltyoleornabtlweolimkinitds"s of information: animal experiments and human ex acomnocuennttrabtiyonwshifcohr athenseormfigalurewsormk-adyayb.e Tehxe ceeded for short periods without injury to pbeasriiecncdea.taTihsecascrrieiendtifiocn rebsyeaprcrihvawtehiicnhdupsrtoryd,ucuensivtehre hsuecahlth asdepthenedsnautpuoren aof nuthmebecronotfamfiancatonrts, sTithiees, rreessuelatsrchoflabsuocrahtoirnievse,staignadtigoonvseranrme epnutablliasgheendcieisn. wshhoerttherpevrieorydshipgrhodcuocnecenatcrauttieonspoeivsoenninfgor, maInnysoUmneitecdaseSs,tapteasrtitceuclhanrilcyalneawndchsecmieinctailfsic, tjhoeurtneaclhs. wquheentchyerwtihthe wefhfiecchtshaigreh ccounmcuelnattriavteio, ntsheoccfruer, and the duration of such periods. All must be cnhiqemueicaollfy aspimpliylainrgmaatnearlioaglsy hawsithsomoetthimereswbeelel-nknuoswedn until valid data have been accumulated. dtaekceisnioninatos tocownshidetehreatrioan hainzardaroruivsinsgituaattiona exists. Special consideration should be given utiTlihzee aclolmamviatitleaebsleorpuobrlgiashneizdatiaonnds ruenfpeurrbeldishtoedabdoavtae etovaltuhaetioanppolficathtieonheoaflththheaszearvdasluweshicihn mthaye ilnevealsrriwvihnigchatwitlhleiprrojvuiddgemeantbsasaiss tfoor thseafekgiunadrsdinogf boef tawssoocoiratemdorweitshubesxtapnocseusr.e to combinations employee health. abTlehriensfhoormldaltiimonitsfraorme bainseddusotnriathl eebxepsetriaevnaciel, Animal Experiments I fsribolme, ferxopmeriamecnotmalbinsatutidoines,ofanthde, twwhoe.nThpeosse values are based on various criteria of toxic phTyshieologtiecchrnesiqpounesesofin eavnaimluaaltsingas atoxmiceoalnosgicof parned dicting possible effects of toxic materials, physical II esfhfoeuctlsd onrotobne musaerdkeads adicsocmommfoonrt;detnhoums,intahteoyr of toxicity, nor should they be considered as alognegntsb,eoenr oathreoruetinnveirotonoml einntalthceonodcictiuopnastioonnaml ahneahltahs dthiaegnsooslies corfitesruiospnecitned porocvciunpgatioornadl isdpirsoeavsiensg. faitetledm. pItrfmspaidtee otof pthriosv,idheowaevsetar,ndtahredriezehdasapbpereonaclhittltoe fieTldhesoef liinmdiutsstraiarel ihnytgeinedneed afnodr ussheouilnd thbee employed by persons trained in this field. imnvanesytigraestipveectstecthhinsiqiusesforitnunianted,usftoriralintodxeicaolilnoggy.wiItnh the effects of a toxic material on a biologic system Tfichaetyionarefornoutsei,ntienndtehde feovraluusaet,ioonr ofrorcomnotrdoil of community air pollution or air-pollution cliosnhseiddercarbitleeriafl.exUibsiuliatlylyisearrelqyuitreesdts inwiallppilnydinicgateesttahbe nuTishaenscees.values are reviewed annually by the cleotuhrasle doofsesfuarnthderthestuedfyfe.ctsThoen mdifafgenreitnutdeorgoafnsacwuitlel rCeovmisimonitst,eeoronadTdihtiroenshsoalds fLuirmthietsr fionrfocrhmaantgioesn, iinmdpicoarttaencteheofsevvaerrioituys orof uttehse oafcuabtesorhpatzioanrd. Caonrdollathrye btheecomsuegsgeasvtiaoilnabolef. sTubhsetanCcoems mtoittbeee awdedlceodmetos the list and also comments, references, or iannfdorpmoastsiiobnle rseylnaetirvgeistitcoefsfpeecctsiecsanvabreiaboiblittayin, esdexa,t athgies, time. All of this information will then provide a basis reports of experience with these materials. In addition to these two groups, the American forInfutthuerec, amseoroef enxetwenssiuvbestlaonncge-st,ertmhestfuirdsitess.tep which pInudbulissthriianlg HthyegiHenyegieAnsiscocGiautiidone Shearsie, s.siTncoe d1a9t5e5,gubiedeens ilsabogreanteorraiellsy inadothpeteddetbeyrmtionxaitcioolnogiosftstooxricitiynduisstrtihael hreasvpeectbseethnis psuebrileisshiesdsimfoirlar97to stuhbestarenccoesm. mIenndamtiaonnys uTthileiszeatioarne ofussucarleleyninfogllotewstesdonbyexdpeetraimileedntasltuadniiemsalosf. oInffoSrmmyathtioinn ihsisprroevpiodretdtofotrheeaAch.I.Hm.aAte. riianl Areplraitliv1e95t6o. aocrutienhefafleacttisonresuelxtpinegrimfreonmts.sinIgnle aindjdeictitoionn,, iinrgrietsattiionng, tthioens;recsoevmemriteyndoefd thmeaxhiamzaurmds a(btmotohsphheearlitch caonndcefnirtrea); effIencts19o5n6sakincoamnpdleetyeescoamrepielvaatilounateodf. acute toxicities tthioensshiomrtm-eexdpioasteulrye thoalzearardnocue;s attomolsifpeh;eripchycsoicnaclenatrnad ufonrdearn theexteanussipviecesseorifesthoef AmearoterMialesdicwaals Lpaubbolriasthoerdy cohfe"mInicdaulstprrioalpeHrtyiegsi.enIen Pardacdtiitcioe,n", burniedferstattheemehnetasdianrge (a5v)a. iTlahbele pduartpaosoen o"facthuitse vtooxluicmitey woafsvtaoribourisngsutbosgtaenthceesr greivcoenmmasentdoedreccoognntirtoioln,preovcaelduuarteiosn. oAflsoe,xpousnudreers atnhde afonrimaselsvearasl destpeercmieisnedofbycoomramloonlrypaurseendteralalboardamtoirny hgievaedninogf "fSirpsetciafiicd, Pprroocpehdyulraecst,i"c bmreieafsudreess,craipntdionspsecairael idsutrcattioionn,toor thinishalvaotliuomn,e otfhefatavlardioousses.s"igInnifitchaentinctoron mgivedenic.alIt pirsocaeldsouressig. niFfiicnaanllty,thaat liisnt eoafchrecfaesree,ncuensdeisr dcoitmiopnosunindfluweenrceingdistchuesseadc.utTehteosxeiciitnyclufodre atnhye gdiovseen, tChoenhceeandtriantgiono,f""RaecstoamtemmeenndtedisMmaaxdime uams Atotmthoesphbearsiics othfeinrjaetcetioonf, aabnsdorpotitohner, rinofultueenocfes,adimncilnuidstirnagtiodnis,eassitee, ofafr thteherecmoomsmt ednedsaitriaobnl.e Twhiasy apopfrodaecahlinrgeprwesietnhts thbye eInnvairdodnimtioennt,, ittemwapserpaotuinrete, dhaobuitt thanatd thtoelertaonxcicei,tyetocf. porfonbulemmbeorfs elesatavbelimshuincgh htoygbieenidcessitraendd.aIrtdsi.s Mexetrreemliesltys ctihmeemsiceavlsenwwillithvardyiffweirtehntspsetrcaieinssofofanthimeaslsamaendspseocmiees. itmhepoersttaanbltishthmaetntalol f atvhaeilsatbalnedainrdfobrme aitnicolnudreedlawtiviteh itto. Wageit,hwineigthhet, sseaxm,eansdtragiennetrhael ctooxnidciittiyonmoafythdeiffaenrimwailtsh. WILLIAMS 991 Btoecbaeuseceorftaainll tthheaste avllarieaxbpleesrimiteinstsviratruealclyonidmupcotesdsibilne pfirnedcisdeelytaitlheed sdaimsceuswsiaoyn. Ionf faalclt,sounchly fraacrteolrys dionevsolvoende inFaonlloewxipnegrimaecncut.mulation of data on acute effects, ilnohngal-atitmioen, cfhereodninicg, eifnfejecctstioanr,e anthdenskisnt-uadbiseodrpttihornouegxh rpeesruimltsenotsf. eTahrleiernastcurreeenoinfgthteessets.isAdtetaercmoinnfeedrenbcye tohne Tinhe195T9ox(i6c)olVo.giKca.l RBoawsies aonfd ThhisreschoowlodrkLerismpitreVseanluteeds awnhicehxtehnasdivbeeesnummmaadrey oovfer tahepekriinoddsofofmoobresetrhvaatnio2n0s ysuemarsmabriyzedsevaenrdal tainbduulastteridalobgsreoruvpasti.onTshoisn dmisocrutassliitoyn, ofogoyd, minitcarkoep,atbhoodloygwy,eihgehmt,atoorlgoagny,wbeliogohdts,urgeraossniptraotgheonl, cclhionliicnaelsteurraisnee. analyses, central nervous system, and paTrtaibculelsarI-eIfVfecstsumwmeraeriozbinsgervthede ufrnedqeurenvcayriowuisthciwrchuimch setraanlcebsiogliovgeicananidndibciaotciohnemoicfalthedestiegrnmifiincaanticoenso. f Tsehve sTiganbilfeiscaIncaendofIIgraonwdththestusidginesificaanndce cohfoltihneestleivraesreanind kinid.Tneaybleins IaIlIl aonfdthIeVs.e Tshtuediaeusthaorres w(6e)llpodienmt oonusttrathteadt tkhinedres iosfinmcreeaassuinregmpernetsssuirne tfhoer mbioorceheamndicamloarendpretocixsie cologic fields as a means of establishing valid threshold leixmcietlsl.enTtheoybjepcotiivnet oauntd, hoonweevtoewr,atrhdatwwhihcihleatlhlisshisoualnd sutsreiveo,f itaviasileasbsleentimalantphoawt eorneanmdakfeuntdhse mtoosotbptarianctitchael mseot stfomrtehaniinngftuhlisinpfoaprmeratiaorne. Tthhoesecrwitheirciah wahreichmaorset wthiedeflyieldu.seTdhaendbecsterthaoinpley faocrceinptcerdeasbiyngallouwrofrukenrds ionf kconmowelefdrogem dthereivdedeveflroopmmenatnimofalnewexpteercihmneiqntuses maunsdt snteawte:criteria. In summary, the authors of this paper newIn csrpitietreiaobfeitnhge dfeavcetlotpheadt atnhderteesaterde tmodaanyy, vthaeluedatoafprceesretnaitned ohferetihne emolpdhearsizcerittehreiah. igIht wthoouseld stsuedeimes ownhliychpreuxdpeenritenctoe hmaaskeshouwsen otof boenlymothstosperocdruitcetriivae.shTohwisindgoeas hniogth mdeeagnreethaotf epfofirctieedncyherineinthsehosuelrdiesbeofusiendv,esbtuigtatcioenrtsainrley ittoxsiucoggloegsitcsalthasttudthyeydesshigonueldd btoe bdaestiecrmtoineanya threshold limit for repeated exposure. anOd nemoorteheratsteetntoiof ncriatereria thwohsiechpihsysaitotlroagcitcingstumdoieres wInhicthhecasnymbepomsiaudme omneanntiiomnaelds aasbwoveell. asDro.n JhouhmnanAs.. Zphaypspi,oloJgr.ic (7o)bsedrisvcautisosends stuhceh iams psoyrsttaonlicce anodf udtiailsitzoinligc T able I FREQUENCY WITH WLHEIVCEHL AATPWARHTICICHULAANRY EEFFFFEECCTT WWAASS OOBBSSEERRVVEEDD A(6T) THE LOWEST DOSAGE Crietfefreicat of GHreomwatthology CCNlinSical urines Cholinesterase Oral a 641 ((17792) ) 41 ((170)9) 8 (10) Data from 1952-1959 % % A. Vapor a 371.3 161 ((3281)) 425 81340.7 01 ((372) ) 03.1 D a2t2a-2f5roymearlsast AH routes a % 1525 ((411700)) 37 2.9 25 ((14431) ) 43..56 8 (10) 80 "Number of positive findings (number of observations) T able II FREQUENCY WITHDOWSAHGIECHLEVAELPAARTTIWCUHLICAHR AENFFYECETFFWECATSWTAHSE OSBOSLEERVEEFFDEC(6T) AT THE LOWEST Crietfefreicat of GHeromwatthology CCNlinSical urine Cholinesterase Data from 1952-1959 Oral a % Vapor a % 250 ((17792) ) 105 21 ((2318)) 55 04 ((170) 9) 03.7 01 ((372) ) 03.1 4 (10) 40 D a2t2a-2f5roymearlsast All routes a % 441 ((411700)) 110.6 05 ((14431) ) 03.5 4 (10) 40 aNum ber of positive findings (number of observations) WILLIAMS 993 ateprpmliscatoifonthtoe hsuigmnaifnisc.ance of such information in maItnerisaulcsh wahnicehxteanrseivesolisltittales tuhsisedthtehreat artehermeaniys Human Experience While animal data provide some basis for judgment nsteagnldigairbdlse pineodpulset.riFaol rexsupcehriemncaeteraivalasilarbellieantcoeaisssipstlaoceudr primarily on animal experiments and the use of abbeouustedthseafpeolyssiinbleinldeuvsetlrsy,ofthteoyxiccamnnaotet rbiaelsexwtrhaicpholamteady to humans with complete confidence. The ultimate anFaloorgythaes mguoidreescionmsmeottninginldimusittrsi.al chemicals many years of experience in using them has provided the cvrailtiedriitay omfussut chcomcreiterfiraomis bhausmedanonextpheerieanmceo.unTt hoef experience in terms of both numbers of exposed nSeuccehssaerxyperbiaecnkcgeroiusndgenteoralvlyerifoyf aexinsetignagtivsetanndaaturdres.. Where it is supported by clinical or physiological data epveaolpulaetioanndoftimthee oefffeecxtspoosufret,heontoxthice mmaettehroiadls oonf people, and on the completeness of the evaluation of cthoerretelant-eydeawr istthudlyevoeflsbouftylexaplcoosuhroel, bays Sitnerntheer acnadse hoisf colleagues (10), the information is most significant. oexf pothsuesree lleevveellss inwitthhe heunmvairnonmexepnotsuarne.d Dcoartraelawtiiothn reference to human effects are obtained from both geSnuercahl mpheydsiiccaall pcroongdriatmiosn aorfeedmepsilgonyeedes taonedvatoluiantcelutdhee specific physiologic tests which may be expected to cexopnotrsoulrleesd. experiments and industrial environment In the case of irritants, for example, such factors parreovibdye feaarrlytheevimdeonsctevoafluianbjlueryf.orStuedstieasbliosfhitnhgis vtaylpide hygienic standards. aesxpoosduorre wdehtiecchtioanre, isrernitsaotriyng rteospeoynesse,,skainn,d anledveulsppeorf respiratory tract have been studied quantitatively in SUMMARY AND CONCLUSIONS hstuumdiaens,s cuonmdbeirnecdonwtroitlhledexcpoernideinticoensg.aiInnedgewneitrhal,acstuucahl forIninshuamlamtiaorny, iint ctahne boeccsutaptaetdiotnhaalt hheyaglitehnifciesldtanindarthdes oprlancot nufisrem, ipnrgovhiydgeieannic asdteaqnudaatredsbafosirs sfuocrh essutabbsltiasnhciensg. bUensittekdnoSwtnatebsioacrheembiacsaeld, toonxicothloegica,ppplhicyastiioolnogioc,f atnhde hItumisamn uecxhpemrioernecediffofircuslut btsotapncroevsidwehiachsoruenqduirbeasirseloaf pexatpheorileongcice. tIencvhensitqiguaetsiontso araenimcaarlrsiedanodn tboy hpurimvaatne toifveilnyjulroyn.gWpehreiroedass othf etimaceutbeefeoffreectpsrocadnucbinegeevvaildueantecde ienrdnumsetrnyt,alunaigveenrcsiietise.s,Trheeseaarncahlysliasbooraftosruicehs, daantda gaonvd rdeeltaatiivleedly srtaupdiidelsy aonf dcboyntrsoimllepdle gprrooucepdsuroefs, ilnodngu-sttirmiael ibnytesrtparnedtaatridosngirnoutpesrmcsomopfohseydgieonficcosmtapnedtaerndtsscisiendtoisntes wthoerkecrasseareofretqhuoisreed stuobsptaroncveidse wadheicqhuatme aeyvidpernocdeucine rfieepldre. sTenhteingvaleivdeitryy offactehtesoefsttahnedaordccsuipsatdioenmaolnshteraatlethd chTrohneickiinnjdusryo.f information which are available from bUynittehde Slotawteso. cVcuepriaftiieodnaclasdeisseoafsesuacthtaciknjuraryte airne tthhee itnhdreuestbriaaslicexcapteergieonricees. wOinthe voafrtihoeusse cihsemlimiciatelsd ftadll cionmto resMulatnyof aepxpproosaucrheessfaarreabboeviengthme aedsetabtolishtheed lpirmoibtsle.m polraiwnittsh amssoorceiasteevdergeenfoerrmallsyowf iatchutteheirrsietantsioorny rreeascptoionnses ohfeaelsthtabfliieslhdi.ngIthybgecieanmice sotabnvdioaursdssoinmethetimoeccuapgaotiothnaatl aseffceocntdingkinskdino, f edyeast,a orersuulptpferromrescpliinraictoalryextraamctin. aTtihone rinesesaormche cpaeseospluetiliinzinvgarvioaurysinpgartteschonfiquthees. wAsoraldrewsuelrte, otofxeicxoploosgeidc wororkphmyesnio. lToghiec tshtuirddieiss. tTheo rebseulotfofvahluuemainn voardlueers offormsaogmnietusdueb. sItanncaens adtitfefemrptbytoasgemt uscohmeasunain etisotnablmisuhsint gbehycgoiernreiclatsetdandwairtdhs asduecqhuamteedidcaatla inrefolartminag pfircoavtiiodne ina thmeecbhaasnicismapptrooacphertmoitthea pmroubclehm barnodadetor teoxpothseed.concentrations to which workers have been ehxecahltahngewoorfkeinrsf,ormthaetioPneramndandenatta Ianmteornngatoioccnuapl atCioonmal StaInndahridss pfaoprerD"aIimlyprIonvheadlatCioonm"mSumniyctahtio(n3.) Hreyvgieiweneidc mtoisssitoundyonthIinsdupsrtoriballemM.edTichiinse sSeutbucpomamSiuttbeceomhmelditteea / G23o8vevrnalmueenst f1roImndutshteria1l9H56ygAiemniesrtiscalinst,Ctoongfeetrheenrcewitohf soyfmTpooxsiicumSubosntanMceasxiinmuInmdusAtrllyowinabPleragCuoe,ncCeznetcrahtoisolnos- /j huiasteidnttehreprnetaattuiroen ooffththeesseupvpaolruteins.g Hdeatah--asanailmsoaleavnald Svaykmiap,osoinumA, pwrilhic1h4-17a,pp1e9a5r9e.dThine Tforaunrsascetcitoinosns,ofdtehael hhuummaann. dAanta ainnadliycsaitsesofthteherofloeuorfksiuncdhs eoxfpseoriuernccees ionf wThitihs gsteanteemrael natreoafs porfinacgipreleesmiesnat namimonpgorttahnet dfeirlestgastteesp. eOsftaablitsohtianlgofhy2g3i8envicalusetsanwdahridchs iwnerteheanUalynziteedd hSutmateasn. ipnoretastnatblfiisehldin.gOinntethrneatbioasnisalofcotohpiserawtioornk iint itshihsopimed dCatlainiwcaelreEuxtailmiziendatiionn1o0f8*W, doirsktmribenuteWdasas follows: onfot aonlsyertiheast wofe ciannterlonoaktiofnoarwllyardatcocetphteabdleevehloypgmieennict CInodruresltaritaeld CWomithplaTihntesirorExOpbosseurrveations 34 swtaitnhdarerdgarvdalutoesgebnuetratlhaptrinacgirpeleems eanntdctaon mbeethoobdtsainanedd LHeussmaQnuaSnetnitsaotriyveDTathaan Clinical Observations 4323 pofroscuecdhuresstanwdhaircdhs.wTillhebepruetisleiznetdSiynmtphoesiuesmta,bwlishhicmhenist Human Toxicologic or Physiologic Data 10 t*hOerfethwee1r1e91v1aludeuspldicisattreisbuwtehderieninthteheabosavme etabmualtaetriioanl wthiell,seIcohnodpe,uncdryesrtatlhliezeaeuvspenicefsurothf etrhetheSutbhcionmkimngitteoef those in the occupational health field concerned with awpepreeaarecdtuaullnyd1e0r8 tsweoparoartemsuobrestahnecaesdinagnsa;lyztehdu.s there esasfteabilnisdhuinstgriaslouenndvirsotnamndeanrtds.s to be used in assuring Index o f A uthors Adams, C. A., 93-98 Agranoff, Barbara, 351-353 AAhlblmahaarrky,, AC..,, 220013--220134, 653-656 Anderson, William H., 656-661 Ashe, William F., 835-839 Ashman, George R., 351-353 Askey, E. Vincent, 62 Axelsson, Bengt, 201-203, 977-980 Balkanyi, N., 465-466 Bambino, C. F., 281-283 Barhad, Bernard, 661-663 Baselga-Monte, M., 663-668 Bauer, Louis H., 85-86 Baughn, William L., 668-672 Bayonet, Natalio, 214-217 Belding, H. S., 839-845 BBeelnkinteazp,,JEullsiotonCLsa.,r2, 1573-12-25632 Benoit, Joyce N., 266-270 Benton, Joseph G., 314-316 Berdan, C., 845-847 Bernath, Zoltn, 227-230 BBiieglgesc,kMa,.WW..,, 719457--719580 Bissonnette, Grace, 230-232 Blatz, Hanson, 463-465 Block, Duane L., 678-679 Bloomfield, John J., 98-101 Bojin, S., 677-678 Bolis, L., 817-818 BBoonnjneerl,l,FJr.eAde.,ri9k3-H98., 672-675, 848-850 Bordes, H. J., 850-857 BBooux,deAnret,hCu.r,, 220998--231041 Brand, Morris, 603-605 Brandaleone, H., 937-939 Breitenecker, Leopold, 675-676 Brennan, Miriam C., 314-316 Brieger, Heinrich, 730-735 Brinkman, Geoffrey L., 678-679 Bronstein, Lewis H., 232-237 Brouha, Lucien, 857-862 Brown, J. R., 862-864 Brownlow, James A., 605-607 Bruce, T., 653-656 Brykalski, D., 800-801 Burger, G. C. E., 864-869 Burney, L. E,, 63-64, 101-104 Cadariu, Gh., 237-238, 676-678 Cancella, Lopo de Carvalho, 56 Cataldi, R., 181-182 Cavagna, G., 770-772 Cavigneaux, A., 203-209 Charsha, R. C., 580-585 Churchill, A. G., 281-283 Ciuhandu, Gh., 237-238, 676-677 Coates, E. Osborne, Jr., 678-679 Cobo de Bias, Eliseo, 238-240 Collins, S. K., 281-283 Colonna, Francis I., 241-242 Conrad, Reuben, 869-870 Cotabish, Harry N., 544-551 Cracuin, O., 679-681 Crisan, V., 237-238, 676-677 Cruickshank, W. H., 105-106 Dankner, A., 237-238, 676-678 Daw, H. T., 86-87,106-110 Deichmann, William B., 871-872 Dervillee, P., 242-243 DDiedsoonilnlea,, HP.i,et2r0o9,-211140-114 Dinatale, Peter J., 244-245 DDionhiascnh, iFo.tuC, .,G1. 8T2.-,138443-345, 679-681 D'Onofrio, Virgilio, 181-182, 958-959 Dossett, Burgin E., Jr., 656-661 Dror, K., 245-246 Duffner, Gerald J., 939-942 Dunlap, M. K., 281-283 Dunster, H. J., 114-118 Durham, Thelma J., 246-249 Dutkiewicz, Tadeusz, 681-686, 795-798 [997] 998 Eckardt, Robert E., 7-10, 64-65 Eckhardt, W., 850-857 Elkins, Hervey B., 981-983 EEsrthaadredltl,aJ-B. oTthh.aG, ,,S.8, 5606-38-56768 1 Fabre, Ren, 686-692 Felton, J. S., 413-426 Ference, Anne M., 12-14 Ferran, G. H., 486-503 Fiandaca, S., 353-359 Finulli, M., 770-772 Fischer, R., 872-876 Fisher, R. . W., 250-256 Folsom, Marion B., 72-82 Formnek, J,, 714-721, 872-876 Fornells-Martinez, E., 663-668 Forssman, Sven, 68-72, 257-258 Fortuin, G. J., 258-259 Fournier, Et., 694-698 Frad, G., 259-260 Frantik, E., 714-721 Frantikov, D., 872-876 Friberg, Lars, 201-203, 977-980 Friedland, I. G., 692-694 Gabor, Sylvia, 465-466 Gasque, Mac Roy, 260-263 Gaultier, M., 694-698 Georgescu, A. M., 343-345 Ghosh, P. K., 426-427 Gillquist, B., 257-258 Glorig, Aram, 699-700 Goldman, Rose, 314-316 Goldstein, Bernard, 263-266 Goldstein, David H., 266-270 GGroardosinpae,, CA.l,fr7e0d0-o70A2., 636-639 Grant, Ellsworth S., 118-120 GGrreimenael,diK, JaotrhinneVR.,.6C0.7,-361048-316 Grimlund, K., 703-707 Gross, Paul, 707-712 Gucciardi, G., 259-260 Guymer, R. F., 270-275 Guyotjeannin, Ch., 694-698 Gwozdz, B., 795-798 Hamilton, Gilbert L., 656-661 HHaarrrgirse,aEv.esS,,,M2a81rg-2a8r3et S., 275-278 Harris, William B., 466-472 Hatch, T. F., 839-845 HHaeryteisg,, WB.aAyl.a, n8d39J-.8,4J5r., 120-122 Hinchcliffe, R., 712-714 Hine, C. H., 281-283 INDEX OF AUTHORS Hinkle, Lawrence E,, Jr., 283-288 Hipps, John G., 608-610 Hogan, Edward J., 610-613 Holden, F. R., 281-283 Holm, A., 257-258 Holmquist, Carl-Eric, 122-126 Holstein, Ernst, 278-281 Holtz, John, 783-785 Horiuchi, Kazuya, 288-289 Horvth, M,, 714-721, 872-876 Hueper, W. C., 473-486 Hughes, James P., 879-882 Hyatt, E. C,, 486-503 Inoue, Toshi, 289-290 International Labour Office, 721-724 IntCeornncaetinotnraatlioSnysmopfoTsiouxmic oSnubMstaaxnimceusminAIlnldowusatbryle, 33-39 Iorga, M., 341-343 Jensen, C. R., 486-503 Juin, Grard, 942-947 Jullien, Georges, 724-726 Kammer, A. G., 427-428 Kantor, M., 753-755 Kazantzis, G., 290-298 Keatinge, Gerald F., 298-301 Keenan, Robert G., 503-506, 783-785 Kehoe, Robert A., 126-129, 433-436 Kesy, Irena, 726-730 Killens, Richard, 783-785 King, E., 301-311 Kingston, James R., 911-917 Kitagawa, Tetsuzo, 506-512 Kiviluoto, Raimo, 311-312 Klein, Irvin, 613-615 Klutas, Edna May, 428-431 Kopp, John, 783-785 Kruger, Daniel H., 615-621 Krger, P. D., 971-973 Kubota, Juko, 313-314 LLaacBhenlliet,, VC.h,a9r4le7s-9W50., 730-735 Laham, Souheil, 686-692, 735-738 Lammers, B., 876-878 Landry, A. S., 512-519 Lavergne, Rafael, 214-217 Lehmann, Gunther, 878-879 Leoca-Radu, Mina, 349-351 Letavet, A. A., 431-433, 891-892, 983-987 LLiibebere,n,AJmaonu, r31F6i-s3c1u9s, 738-740 Lienhard, Wendell F., 879-882 Lillis, R,, 679-681 INDEX OF AUTHORS 999 Linch, A. L., 580-585 Lind, A. R., 882-887 Liniecki, J., 800-801 Littler, T. S., 712-714 LLuubnidn,,OI.s-aEd.o, r7,406-2714-1622 Lundervold, Arne, 887-891 Lutier, J., 401-402 Lutz, Earl F., 184-186 McCallum, R. I., 741-745 McClintock, R. S., 879-882 McKerrow, C. B., 745-749 McNerney, James M., 707-712 Magnuson, Harold J., 129-131 Malysheva, A. E., 891-892 Manheimer, Robert H., 314-316 Matthews, James, 131-134 Matuoka, Syukiti, 893-902 Maxfield, Mary E., 857-862 Meiklejohn, A., 134-138 Meila, I., 677-678 Metzner, Franz N., 316-319 Michon, R., 902-904 Mihaila, I., 904-908 Mikaelian, Michel, 320-322 Mikisha, A., 714-721 Milijic, Bosko, 950-951 Miller, S. E., 937-939 Milox, M., 908-911 Minard, David, 911-917 Miskolczy, Wilhelm, 322-324 Mitchell, R. N., 486-503 Moise, Gh., 676-678 Molfino, F., 952 MMoonrraicso, ,GAelofrrgeed,E7.,493-27453 MMoorscroowvi,ciC, .BS.,-,374513--374535 Moss, N. Henry, 182-184 Motley, Arthur W., 623-624 Mountain, John T., 783-785 Moyer, Burton J., 519-522 Muica, N., 679-681 Murray, Robert, 139-145 Nadudvary, George, 465-466, 755-757 Nale, Thomas W., 625-628 Namba, Tatsuji, 757-758 Nestorescu, B., 679-681 Newnham, C. T., 324-325 Niebroj, I., 795-798 Nixon, James, 699-700 Noro, Leo, 326-335 Norviit, Lembit, 952-957 Norwood, W. Daggett, 335-338 Nystrom, A., 257-258, 653-656 Olloqui, Fernando Flores, 628-631 Oyanguren, Hernan, 227-230 PPaafgngoi,teE, dMoaarrdiao,, 874558--874677 Pancheri, Giovanni, 145-146, 767-768 Parker, H. G., 147-150 Patrascu, M., 465-466 Payne, William W., 473-486 Pendergrass, Eugene P., 768-769 Pendergrass, Henry P., 768-769 Perales y Herrero, Narciso, 631-632 Pernis, B,, 770-772, 817-818 Pesce, Giuseppe, 958-959 Petrescu, Leonid, 661-663 Pettinati, L., 348-349 Petrovic, Lj., 338-341, 368-371 Phillips, A. M., 553-556 Pietschmann, H., 947-950 PPiiolattr,owL,,sk3i4, 1J-.3, 4738,06-77892-681 Piscator, M., 201-203 PPlluummbm,eCr,arNloSr.m, 2a6n0,-226833-288 Poleti, D., 338-341, 368-371 Potter, A. Lloyd, 150-155 Powles, William E., 351-353 Pradel, J., 522-531 Preda, N,, 343-345 Princi, Frank, 433-436 Puertas, Benito Nogales, 633-634 Quer-Brossa, S., 663-668 Quigley, J. A., 65 Radcliffe, J. C., 65-66 Rdulescu, I. C., 343-345, 679-681 RRaaein, sSfoterwd,arSt.,G7.7,23-4757-6348 Rasetti, L., 348-349, 359-361 Raucher, Karl, 349-351 Reeve, A. Louise, 634-635 Renker, K., 917-921 Riedesel, M. L., 839-845 Riegrt, A. L., 819-825 Rigner, K. G., 257-258 Risquez-Iribarren, Rafael, 155-158 Rogan, John, 772-776 RRoossss,i,WM.aDrioon, a9l6d0,-396511-353 Rossier, P. H,, 776-780 Rotta, C., 353-359 Rubino, G. F., 359-361 Rye, W. A., 361-364 SSaaklmaio,wYao, sJh.i,m'7i8c0h-i7,81258-162 Sands, Frederick W., 531-532 Santillan, Jose S., 636-639 Sarfeh, R,, 436-438 Saruta, Namio, 532-535 1000 Savicevic, M., 338-341 Sawyer, William A., 438-441 Scansetti, G., 348-349 Scheel, Lester D., 783-785 ' Schepers, G. W. H., 786-795 Schermerhorn, W., 850-858 Schiller, Hans, 961-962 Schindl, Karl, 364-365 Schmidt, Heinz-Giinther, 365-367 Schmidt, Marjorie D., 367-368 Schmidtke, H., 921-923 Schulte, H. F., 486-503 Schunck, Karl-Hans, 377-378 Schwartz, Louis, 639-642 Seles, L., 237-238 Serati, A., 963-965 Sherrill, S. S., 281-283 Shipman, Thomas L., 642-645 Shoib, M. O., 85, 162-166 Sick Absence Statistics Committee of nent Committee and International on Occupational Health, 40-55 Silverman, Leslie, 441-448 Simpson, H. Marjorie, 448-452 Simu, George, 755-757 Smith, Paul E., Jr., 857-862 Sodergren, David, 122-126 Sox, Ellis D., 281-283 Spett, K., 795-798 Spiers, F. W., 535-540 Spioch, F. M., 795-798 Stankovic, M., 338-341, 368-371 Staskiel, L, J., 753-755 Steele, Earl C., 371-373 Steele, Margaret L., 66-68 Steiner, S. D., 373-377 Stokinger, Herbert E., 540-544 Stopps, Gordon J., 857-862 Stowell, Thomas E. A., 186-191 SSutrmanngere,, PJohhilnipP, .3,1544-43-15651 Symanski, H.-J., 798-800 Szpakowa, T., 800-801 Szymczykiewicz, K., 801-805 INDEX OF the Perma Association AUTHORS Udel, Melvin M., 397-401 Ursoniu, C., 676-678 Vacher, J., 401-402 Valentin, H., 810-817 Van der Velden, W., 850-857 Van Liew, Hugh D., 911-917 Van Valzah, H. J., 678-679 Vigan, C,, 965-971 Vigliani, Enrico C., 87, 452-457, Viles, Frederick J., Jr., 556-563 Villarroel, Sergio, 227-230 Viola, P. Luigi, 818 Voelz, George L., 564-569 Vosburgh, B. L., 931-933 Wade, Leo, 7, 61, 88 Wald, Neil, 569-572 Walker, Mildred I., 167-169 Walsh, Richard F., 645-648 Warnock, Dorothy M., 402-404 Wassermann, M., 572-580 WWeeachveserl,bNeregilelrK, F.,.,38119-13-81794 Wells, R. Lomax, 170 Westrick, Marian L., 707-712 Wetherhold, J. M., 580-585 Wheatley, B. M., 585-587 Whipple, G. Hoyt, 171-178 Whitney, L. Holland, 283-288 Wiecek, E,, 801-805 Wieland, H., 740-741 WWiilllliiaammss,, KCahtahrelersinRe,.,598878--599904 WWiilllliiaammss,, NM.a, y81M9-.,821594-197 Willman, Helvi, 404-405 Winter, Kurt, 405-410 Worth, G., 826-827 Wyndham, C., 924-931 770-772, 817-818 Tabershaw, Irving R., 11-12 Taylor, Edmund W., Jr., 182-184 Teisinger, J., 987-988 Teso, G. A., 359-361 Thaxter, M. D., 147-150 Thom, W. F. J. M., 379-381 Thoma, George E., 569-572 Thompson, A. R., 301-311 Thorpe, John J., 381-387 Tompkins, Paul C., 551-553 Tripsa, Rodica, 806-810 Troisi, Fortunato Maria, 387-397 Truhaut, Ren, 33-34, 39, 209-214, 686-692 Tucker, F. E,, 553-556 Yingling, Doris B., 457-459 Yoder, John D., 590-592 Yoshimi, S., 827-828 Yount, Hubert W., 649-650 Zahorski, Witold, 828-832 Zanetti, Ennio, 767-768 Zannini, D., 971 Zielinski, John F., 592-600 Zorn, 0., 971-973