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University of Cincinnat i M edicai Cent er D E P AR TM E N T O F E N VIRON M EN TAL. H E ALTH KETTERING LABO RATORY 1313) 872-5700 3223 Eden Avenue Cincinnati, Ohio 45267 November 28, 1978 * M. K. Williams, M.D. Chloride Automotive Batteries Ltd. Chequers Lane Dagenham, Essex England RM9 6PX Dear Doctor Williams: Thanks for your letter of November 17th. I think I should tell you a bit about my making data available to you, so as not to disappoint you in the process. Let me say at once that I am delighted with the prospect of seeing and talking with you. Also I can show you published papers which present and interpret reams of data on specific parts of our investigations. The over-all assembling of our data on specific persons and groups of persons is yet to be done in order to provide a compre hensive picture of our work, and I shall be engaged in an attempt to do this for at least another year, for I work slowly as a matter of necessity. I have no reluctance to take the time that will be necessary to give you a fairly general and yet a fairly comprehensive view of what we have done. Fortunately, with reference to the approximately thirty-five years spent in the study of one group of four human subjects to whom inorganic lead was administered orally, and of another group of twelve, who were subjected to the inhalation of inorganic lead in air, in various concen trations and particulate sizes^; a series of progress reports were made from time to time (and published) so that some grasp of the entire (or almost entire) work can be had. There were in this study some thirty thousand analytical results alone, not to speak of the day to day, week to week and month to month, records of physical and clinical obser vations of various types which were made. It is, of course, a heroic job to assemble these data in such form as to be seen and appreciated, and this is what I am now doing, after the lapse of more than ten years in which, after my retirement and a disabling cerebral hemorrhage I recovered to such an extent as to get back to work. Thus, the best I can do to make this work available to you now, will be a bit difficult and incomplete. I am not complaining about the difficulties, but I am telling you in advance not to be too surprised at the incompleteness of my present efforts. *and for various periods of time, daily. i*.A-.yw j .y g j j iRjr . * 0003785 N9830 j i Page Two November 28, 1978 With this reservation, I shall be, as I have said, delighted to see and talk with you and to display what I have done thus far to make the data and their meaning available. I look forward with great pleasure to seeing you again. I really mean that literally, for my difficulties of one kind or another have isolated me from my former associations to such an extent as to give me a very considerable feeling of loneliness and ineptitude. Pat Barry has continued to be a source of great satisfaction to me,:and many other friends above all my wife) have supported me in everything I have attempted to do, so that I feel very favored and most fortunate, despite my various types of partial disability. With kindest regards and best wishes. Sincerely RAK:di Robert a . Kenoe, m .d . Professor Emeritus of Occupational Medicine K E" 0008786