Document yEO9Bm73d5xrJmYRZddV3eR4

0683 Chmtirul Ahslnuls 0684 V..I c,2. | mi;.*, of quartz have hcen demonstrated. Modifications of the matrix theory may explain silicosis as a p:itln>l. jiroccss resulting from the rnol. anil Structural makeup of silicic ucul. Over 154 ref erences. W- C. Tobie E*rly silicosis. C. Worth, U. (Vtstliaus. K, Muysers, ami F, I'reila. S. Alinitlc.ui, l.iana . ..uiof, Am-.i, anil Clara V.durz- kay (Inst. II vg. Cluj. Koui.iina ). /glee 'hu-harrst) 13i 5), net I8( l!K>4 J( Rom). "I'lie blond nf 78 workers of a jiolyt vinyl eltlo- ride) plant wax investigated. Found were decrease, sf albumin and increase of 0- ami ygloluiliii fractions in serum proteins, iH-- SichofT (Kratikeiihaiix Orafschafl, Mm-rs. tier.). /Intr, .Silt- a crease of the d to n ratio id serum lijinproleiiis, and decrease of kase-Forsek. No. 83. |-63( 1964). Physiol., pathol., and x*ray the scrum cholinesterase and pxcudocholinestcrusc activities data were detd. on 365 coal miners a ceil 1>'I 39 years m comparison Blood catalase .old serum pvruvtc acid were iioriti.d. ltd' IO With 20 healthy workers in the same age group not exposed to .Pathomorphology of brain elements of white rats with chloro- dust. Early silicosis, beginning witlmt 111 years, was detected prene poisoning. T. H. Movscsyun. A. V. Mtutsuk.iuvan, .uni in 285 of the coal miners. Vital capacity of the lungs and forced _ (1. Kli. (i.dstyan. /re. Ak/id, Sunk ,1 rm. .SSK. Ihnl. Snnkt 17 respiratory vnl. were significantly lower in the miners, regardless (ft). 51-811(164 )( Russ). Results are reported of histol. invi-n. Of dust exposure or the ih velopmetit of silicosis. Over 5t)'.l of gatious of the cerebral cortex of white rats exposed ti i Ifforopri ue the miners with early silicosis required a greater respiratory vol. (I) during 6 months. The chronic effect of ( in do es from n 5n for a given uptake of O than dpi the 25 controls. The arterial ing./tu.* to 3.06 mg./m.1 caused intense dystro|ihie cltanges 111 pOt in miners with pneumoconiosis was lower than the av., while the cerebrum. Ill general, all dystrophic changes in the cortex the alvcolo-arterul gradient of O was higher, both at rest and , led to atrophy and wrinkling of some cells, swelling. tigroU-i, during effort. These effects were related to time of exposure to and hypochromatosis of other cells and dually to the acute swell coal dust, although not in correlation with the x-ray findings. ing and vacuolization and destruction nf cytoplasm. The last Analysis of expiratory argon pressure curves showed that ven changes are more sharply expressed in the elements beneath the tilatory troubles occurred in 5.6`T of relatively young miners with cortex and medulla oblongata. In the circulatory system. Iivjio- early silicosis from 10-15 years of dust exposure. Abnormali tonia of vessel walls and proliferation of the endothelium take ties of gaseous diffusion also occurred. However, there were no place. M. Cliarmandarian significant differences in the acid-base metabolism in early sili Examination, of urine for porphyrin in some occupational. cosis as compared with that in the controls not exposed to dust. poisonings. A. I'etrova and I). Bakalov. Khigiena (Sofia j 6t 4). 19 references. W. C. Tobie 37--Hi 1903)(Russ). Urinary exainn. for pnrjihyrins was carried Mercury vapor in dental offices. \V\ Ketteri and K. Lira- out in subjects with occupational diseases and in healthy individ precht {Univ. Munich, Gcr.). Deui. ZahneicrtU. Z. I9( t2), 1104- g uals, The results obtained are compared with those of liver- 9(1964), Hg contamination of dental offices may stem from furction tests and urinary excretion of urobilin and urobilinogen. open storage or from imp'oper technique in prepn. of amalgams. Inc-eased urinary coproporphynn excretion is a very early and Fingers contaminated with Hg are not completely free of Hg 20 sensitive indicator of liver damage. The itivesttgrtion covers 19 min. after thorough soap and water washing. Measures sug forms of poisoning, 3 being combined. Coproporphynnuria is en gested for minimizing the contamination of dental offices are dis countered in 13 forms of poisoning, viz., ligroine. benzene, Pb, CO, cussed. Henry M. Koehler -- Hg, Cu. S gases, TNT, MeCl, aniline, Me;CO, ix^N, and NaOH Hemocoagulative modifications in chronic experimental poison -1- liquid soap, A more thorough investigation was carried out ing by tetryl. E. Damele i Umv. Naples). Folia Mod. (Naples) by performing urinalysis in subjects poisoned or subjected to 47(8). 7(37-76( 1964KItal). The possibility was studied of detg. the noxious effect of gasoline. Coproporphyr nuna is a sensi early or latent changes in coagulation and an increased tendency tive and more frequently encountered indicator ;n occupational to hemorrhage, esp. of the throtubopluhc type, even when tests poisonings, even in the presence of extremely mile liver damage. prove neg. for subjects exposed to tetryl. The studies were d Urinary coproporphyrin excretion is very frequent in gasoline carried out on 15 rabbits; 2 were kept as controls and the others poisoning; it may even appear in apparently haaNhy individuals, were given 0.125 g. tetrvl /kg. body wt. orally for 6 months. who are in continuous contact with gasoline Bjsks. From Abstr. During the entire penou the following tests were made; throm- Bulgar. Set. Lit., Med. Phys. Cu'i. 6(4), 34(196.,). TCFR boelastograms, prothrombin time (Quick j, prothronibinrmia, The maximum allowable concentration of dibutyi phthalate. accelennemia. convertmeniia, and a direct blood platelet count__ Mincho Spasovski. Khigiena (Sofia) 7(1), 38-44t 1964)( Bulgj. (Palumbo and Diiii). Blood was collected in a sdiconated tube. The phys. and chem. qualities of di-Bu phthalate (I) are pointed After 6 months the following changes un had occurred: out, the toxic parameters are established, and its acute and prothrombin time, from 96.3 to 68.1, prothrombmemia. from chronic effects on 299 different kinds of test animals are studied. 96.6 to 75.2; accelerinei na, from 95.9 to 90.7; convertinemia, The author det. 0,001 mg./I- of air as the max. allowable concn. from 95.8 to 72.3; plmclcts/cu mm., from 507,530 to 498,640. of tech. I, heated to over 140, on the basis of examtt. of condi Even though some of tlie factors did not change significantly, the c tioned reflexes, latent period, weight coeff. of liver and kidneys, general blood coagulation picture was definitely altered by total body wt. motor activity, and fatigue. The toxicity of I chronic tetryl poisoning. The possibility of intravital hemoly depends on its routes of penetration into the organism. The sis is considered. The most definite entity was the decrease in vapors of I, heated to over 140, are most toxic, causing like coagulability. Felix Saunders wise pulmonary edema, I is less toxic in peroral administration, Establishing hygienic norms for some caprolactam intermedi it has no skin resorptive effect. It possesses a very strfang cumu ates in the atmosphere. A. A. Dobnnskii (Central Inst. Ad- lative effect when inhaled or applied by mouth. The cumula vanccd Med. Training. Moscow). Gtgirna t Sanit. 29(12), 8-13 tion coeff. is <1, explained by the development of high I sen (l9G4)(Russ), The following concns. of cyclohcxjnol (I) and sitivity, From Abitr. Bulger. Set. Lit., Med. Phys. Cull. 7(2), cyclohexanone (II) m ing./cu. m.. resp.. arc reported: threshold Abstr. No. 409(1964). TCFR for detection by odor, u.1'4, U.21: by iiiilucnce on dark adaptation Carbonic anhydrase In occupational lead poisoning. A. of eye,--,0.11; detected by effect on elcctrocortical conditioned , Batoiska. Sauchnt Tr. Nauchnoizsted. Inst. Okrana Truda responses, 0.14. 0.11; recommended single-exposure max., 0.06, Prof. Zabnljavanija 10 , 55-9( 1963)(Russ). Examns. and lab. 0.04. liats were exposed to atms. contg. 0,059 mg. 1 and 0.042 investigations were carried out on a scries of 81 workers from a mg. II. resp./cu. m. for 81 days with no observed changes in mus Pb works. Besides the characteristic Pb-poisoning indexes, cular clironaxy, cholinesterase ictivity, sulfhvdryl blood concns., the changes in carbonic anhydrase activity were also detd. Simul or ascorbic acid concns. in brain and kidney. I and [I were detd. taneously with deterioration of the general phys. condition, a- spectroscopically using the absorptions at 510 and 550 nia. resp. -- far as Pb intoxication is concerned, carbonic anhydrase was John Howe Scott also depressed. Pb poisoning brings about a depression (alreaffv Hygienic evaluation of the synthetic flocculant polyamide, proved in vitro) of the enrvme iti vivo. From Abstr. flulgar. .S, i. Mark PAA. .V A. Rakhmamna il. M Scclicnov 1st Med. Lit.. Med. I'kvs. Cult. 6(4), 32(1963). TCFR Inst., Moscow). Gigtena I Surnt 29(12), 20-31 1964 It Kuss). Carbon dioxide transport in the blood of patient* with silicosis The L.I) values of polyacrylamide (1) for mice and rabbits are and silicotuberculosis. Klir, Tsolov. Nauchnt Tr, Samh- 12,950 and 11,250 mg./kg., resp. These may be due to the <7 nnizilnl. In it. Ohmnn Trntn /`riif.Zabiitjavnntja 10, 77-8,3(19631 monomer present. Hoses of 1.5 mg /kg. caused changes m the (Russ). I he transport of CO, in the blood is studied in 27l> pa conditioned reflexes of rats in 9 months. i he recommended max tients affected with silicosis (with varying degree of nianifv-i.i concn. of I in drinking water is 2 ing./l. John Howe Scott turns of jialhot.) and sihcntuhcrctilosis. The partial U( l. tension Coniosis hazards of a scries of refractory materials. It A. in alveolar air is relatively low, tint it is higlu-r than in artin.d Katsncl 'soil. M. J;. lemyascv, U. (*. It iluishkma, .util 1, N. hlood. The CO. phys, dissolved in the blond is also dvcriMsid. Kl'nichnykh I Mu), Insi., Sverdlovsk), togooiii t .\init. 29(12). The total aqd plivs. dissolved amt. of C'fh in the venous blood i30-K( 1961 )i Russ). Inis)- nf various reii uetni n - were intro within normal physiol. limits. The venous-ait eri.d dilhrem, i- duced intrutruchr.dly into rats and tin itfeets studied during 9 months histpl. and by ffeln. of liydnixvprolitu- and lund emails. The following group- well' prugressn civ Us- h.undid, quaii/ue arnl dm.is. rhninottr, clay i!2', frei Sii i I, .uni foi-uiiie; mug- nositc, ninl ehriiiiioiii.igiusile. The rccoimiuaided m ix. fm these groups are I, 2, 5, and IU nig./ru. ill. air, rtsji 1'iliU I Imivi Scott iiisigiiificaiit. The progressive deterioration of ihe silieate to ilnced prows* results in a comparative liUTi-nsc of thr partial I'l > tension as well us of its jihvs. dissolved p.irl in the arterial .on! -till more in the venous blond, with eorM's|Muubiig decrease ol 11 nvcninis-arterial dilTert lice, A state of hipoe.ipiiia is also ..b Served ill jiaticnts with silicotidierrtilnsis Ihe sepii. of O' from the blood of patients with evtotone bv posctinn m i iiis I........ Biochemical changes in workers occupied in vmvl chloride the most difficult, whereas in those with anemic liv pon mi.i It synthesis and polymerization. Silvia t .ubnr, Mma Kudu, N'. least. The acid-base balance in the blood of patients with sdi BOR 009701