Document y055reZQ7jDG5J4zQXb18ZOX

Getober 'Ist. 19SU. o? t ps trosiip si. fo r tb a P r e s s t o b d eles a d October 31s t . Tn eon n octen w ifh th a u s s s n a l cir cu s s in n e e s t t e a iio s : tm c'esth o f e e r t s ia in d ivid a le 1315!oye'? in con d a ct in g axn er iiaen tfl 'mtg; ui'il t t r a e t fe s l l e s ! in th a Thyuey la b o r o .t o r io s o f t h e Stan d ard C i l Coaoany o f '%u . r e e y, th a iiee er t -mnt o f th a I n t e r io r , throuifo t h e Bureau o ?*inea, c o l i s a t t e n t io n t o th a 1i f fo r neo b ot veen t e t r o s t h y l ic s d &oA St h gl G a s o ils . Theee t s u o r o d u e t s , u h ieh n r e c u it e d iffe r e n t -, p m d 000a t o bave "hseoiss co n fu s e ! in th a nsirvts o f th e n u M ic '-s th e r e o it o f frase accewmts o f t h ie u m s u a l s c e lle n t . Con sid er a b le o u b lie !t y hn s b a os r le s n t o t h e otntaaa&nt t h n t th e p r o d u ci c a a s ia g t h e p o iso n !n g o f thooo n a r sen s uns Hthyl Oosolin o, t h s n r od u ct s s o l3 t o su to M le o n a sr 8. Th is i e orronooos ths ^ artaent p oin ts eu t. as tbe op eration of th e La b o r a t o r ie s r e fe r e t o tb s p r ocs o f in swafecfcure-of tho con estitrrj.te3 ie t r e o t fb yl l e a ! . Th le p r od oet i s n ot s o i ! t o au tom ob ile d r ive r e xe e p t .ufam tBem n &ou aiy d ilu t e d r r it h o n s o lla e . ?etr'setfcyl le a d in n ot in i s e l f sa* a m in e fs l and i s o n ly u s o l in ."r ca t ly d ilu t e d fo r a , comeiy le s o th on en e art o f t a t r a e t fcy lo a d t o ona ihoueend arts o f ga s o lin a b y volum e. _ eue o f thp.- o n t e t a n d in * orofelsm ' c o o fr o n t im s t e s t ive on ^ in eer s in KE 0017679 " attesantiag to coastruct sa to rs of ^ re ste r ocooosy is th at o f slladn& tlng the s e - c s lls i "Vrack" fro a th e operation o f the engin. I t h heon dSHonstrated tsat t h ls "knock* can be c o n tro lle r h the a d d itio n o f essili esentiti o f c e rte i n finid* Ths sa tsria la s&sB i t ocsible to ose e a tis f e c te r l a lo ^ e r grado o f gasotlao an to" us englnee of a onr seonealcn type. The pin, l a f n d eon eerm tto a o f 'hoth tn ereesin g tha m rtio n o f erede c i l a stitetb e as ssotor fa s i ad a le e p e rs i tt-lng1th e designi!*? o f to r s s f f ie e n t salines m e obvions to th Harem of klnee. Their a tte n tio n mus caie d to the o e s s ib ility of h o sith hasards l a ad dition to thos of carbon saonaside freos eshaost ganos. .?>s a r a s s i t the in v e stig a tio n o f ths oroduets m s nadertaken. The Tabom tcry oork ans coMneted by the Daarfessent of I n te r io r s t the Pittstrargh T tstio o o f the Barosa o f Tines nadar th d ire c t s a a e r r ls le a of i t e eehniccl s ta f f . `.'ne o f the saoet eoaoaly peed anti-knock eompooods i s knosa a s te trn s th y l l e a l . Thls is sdded to ^ aeolso in misnfcity o f le s e tfcan oao p a rt o f te tra e th y l ead in cne thmssand p a rts of gasoline hy voies a n d 'th ie mixture s o li on the mnTket as -tkyl Casaline. The problema of the h a a lth hastsri ne to the se of ts tr s e th y l le a d sy ho 'i r i d a i ia to th ree p a r ts . 1. J hasard in the aasnfectnring' ani henil lag; of tba concentrate^ to traeth y l load. "M s h-nsarl cecero in fho nsnafnctaring p la n t. ? Tic p o ssible hasard in hsndlln^ tiw lthyl Gasoline (one art o f te tr a o thy le a l to e m thousand marts o f g seo lin e. This p o ssib le hasard assy a ff e c t those handling Ethyl Hanoiins. 3. The pass Ib is hasord doe to the exhm st gneee fro 'cntaaobilee u sin g Sibyl Gasoline. This possible hasard concerns the e n tire public. >'ha scope of tbs wewteuaiertafcos by the bureau of line iadudcd an in vestigation of ail possible haesrds m outlined la the above. The first two parts* namely that of the danger in the manufacture and handling of the concentrated tetractiyl load and the possible risk 1a handling the Sibyl Gasoline as sold to the <mtesobllo driver, are nowbeing investigated. sufficient data has hot bees obtained to drawconclusions to date. As soon os this investigation has teen csoaplotod the revolts will ho 'rsAo public* `Use l a s t p a rt of the above ou tlin ed problems, nsaaely the 'possible hasard due to the exhaust gases fro automobile using Ethyl Gasoline a s o rd in a rily so ld ''os been c arried on f o r more than ten scath e. The plan of In v e stig a tio n r?as th a t o f exposing various types of snistals (pigeons, goinea p ig s, ra b b its, dogs and mchkeys, over 100 in s l l ) to a d e fin ite concentration o f exhaust gap from an engine using litfcyl Ousel in o . The concentration o f exhaust gas in a i r used nas. th a t which, rhea coming from the average reatorsobilo would bo four p a rts carbon aoaexide i s te a thousand oarto o f a ir ; th is concontra- tio n wend. 3 he allo-aabl f o r "bat a period o f one hour exposure from th e standpoint o f carbon monoxide. (The concentration o f exhaust <53 in a i r used m n such as to exceed th a t 'mom to e x is t inordinary t r a f f i c o f & c ity s t r e e t . ) The carb u rete r "?as adjusted so th a t the carbon monoxide content of the exhaust gas frost th e engine used ms la s s than ono-half th a t found in the overage automobile exhaust gases. The animals ere divided in to three rep resen te t i r e groups. The f i r s t toe groups se re exposed fo r periods of three and s i s hours resp ec tiv e ly and the t h i r l group not exposed but used as co n tro ls. The animals po t thus d a ily exposed f o r th ree and s ix hours over a to ta l period of approximately e ig h t months to a `cnofnx concen t r a t io n o f exhaust gas. Those exposures were such th a t the le a d con te n t o f tbs a i r breathed by the anissals was sim ila r to th a t which would r e s u lt -hen., exhaust gases o f aa average automobile using Bthyl Gasoline a re d ilu ted so as to contain about fo u r p a rts o f carbon monoxide to te a thousand p a rts of a i r (the per m issible exposure fo r on boar from tb s standpoint o f carbon monoxide poisoning), 'ib is was a considerably higher concentration of exhaust gas than could o rd in a rily occur. The animals ware observed throughout the e n tir e t e s t period f o r symptoms of lead poisoning, as c o lic , p a ra ly sis, lo s s o f a p p e tite and lo s s of w eight. Mno, s carefu l examination o f the blood was mad f o r c h a r a c te r is tic signs o f lead poison ing. a t various tim es animals wore h ille d oral the e n tire tis s u e s examined fo r e ffe c ts o f lend sad analysed fo r 3tord~tK> lead After a period o f aooroxlsssfcely e ig h t months d a ily exposure to t he above c o a litio n s th ere was no in d ic atio n o f lead poisoning. Tho sairasle continued to /prow anri mature a t a noraal r a te . One o f the dogs gswe b i r th to fiv e pt5pie. These aero continual on te a t with the mother and in the course o f the t e s t matured n o raa ll7 . <a absence o f lead poisoning aay bo cits to the sn a il amount o f lend p resen t in the exhaust gas s i r (fixture. TurtheTsaore, cbsonr&tione made on ram showed th a t most o f the lead in exhaust gases cooing from Sthyl Caroline when inhaled i rgnin exhaled. The in v e stig a tio n c arried out in d ic ate s the danger o f s u ffic ie n t load . oecm aiation in the s tre e ts through the discharging of seal from autoasobilo motors to be sestniogiy remote. *ha in v e stig a tio n o f tho p o ssib le hasarda of load poisoning from exhsnst ^ s o s i s being continued a t the iits b e r g h S ta tio n o f the Sureen o f Minas, to g eth er p ith the f i r s t two phases o f th is study. KE 00176.83