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FILE NAME Orton ORT DATE 2016 Jan 14 DOC ORT016 DOCUMENT DESCRIPTION Legal - Declaration of Barry Castleman PAUL C. COOK SBN 170901 DEBORAH R. ROSENTHAL SBN 184241 BENJAMIN D. GOLDSTEIN SBN 231699 SIMMONS HANLY CONROY 100 N. Sepulveda Blvd. Suite 1350 El Segundo California 90245 4 Tel 310 322-3555 Fax 310 322-3655 5 6 Attorneys for Plaintiffs 7 8 SUPERIOR COURT OF THE STATE OF CALIFORNIA 9 FOR THE COUNTY OF LOS ANGELES 10 11 ROGER PACKETT individually and as successor to DONNA L. 12 PACKETT deceased ) Case Nos JCCP4674 & BC525735 See See DECLARATION OF BARRY I. 13 Plaintiffs Nee CASTLEMAN ie : VS. 14 Nee ) Date . January 14 2016 15 ALLCRAFT JEWELRY SUPPLY CO et al Be Time ) Department 1:45 p.m. 324 Hon Emilie H. Elias 16 Defendants ) Complaint Filed October 25 2013 NY Trial Date February 16 2016 17 Nee 18 I Barry I. Castleman declare as follows 19 1. am over eighteen years old and not a party to this action The information stated 20 herein is based on my personal knowledge and if called as a witness I could and would testify | 21 to the following 22 Qualifications 23 2. hold a Bachelors degree in Chemical Engineering a Masters degree in 24 Environmental Engineering and a Doctor of Science degree in Health Policy from Johns 25 Hopkins School of Hygiene and Public Health I have more than 40 years of professional 26 experience in the area of asbestos and other occupational and environmental health problems 27 Currently I am employed as an environmental health consultant Attached hereto as } 28 DECLARATION OF BARRY I. CASTLEMAN Exhibit 1 is a true and correct copy of my curriculum vitae If called upon to testify I could | 2 and would testify to the qualifications contained therein 3 3. have studied development of state of the art with respect to medical and scientific 4 issues relating to asbestos and asbestos diseases for more than 25 years I have reviewed S hundreds of scientific medical and corporate documents concerning the hazard of asbestos and 6 the development and history of the knowledge of asbestos hazards In addition to publicly 7 available medical and scientific literature I have extensively researched and reviewed extensive discovery from asbestos litigation including depositions documents and interrogatory responses from asbestos industry companies and their officers and other employees I have 10 undertaken extensive research in public and private libraries in the United States Canada and 11 other countries This has included U.S. government archives institutional archives and the 12 archives of scientists I have reviewed extensive internal documents of companies involved in 13 the asbestos industry including mining companies oil companies friction product 14 manufacturers insulation manufacturers and contractors and railroads I have reviewed trade 15 association periodicals and meeting minutes corporate documents and testimony of doctors 16 plant managers executives and other people who were aware of events that transpired in the 17 history of developing asbestos knowledge over time | 18 4. In addition to published information and corporate knowledge that came out of 19 mainly legal discovery I have also interviewed a bunch of timers in the field of industrial 20 medicine and hygiene They included physicians who were active in the field of occupational 21 medicine such as Harold Stewart who first published on asbestosis in 1931 and Alfred 22 Angrist who first published on asbestos and lung cancer in 1942. They are both pathologists 23 Another Dr. Wilhelm Hueper was a leading United States authority in the field of occupational 24 cancer and first director of the environmental cancer section of the National Cancer Institute 25 Dr. Irving J. Selikoff was the leading epidemiologist and asbestos authority in the US Dr. 26 Hueper Dr. Harriet Hardy Dr. Thomas Mancuso Dr. Gerrit Schepers Dr. Richard Doll Dr. 27 2 28 DECLARATION OF BARRY I. CASTLEMAN Morris Greenberg and others I have interviewed were involved in the area of asbestos and health over the past decades 5. have been qualified as an expert on the history of the asbestos industry and the development of knowledge about asbestos and its hazards also known as state in S numerous asbestos lawsuits including those that have been brought in California courts I have 6 testified as a state of art expert in many asbestos lawsuits I periodically testify before 7 congressional committees and have served as an expert consultant to many organizations My 8 expert testimony is on the subject of my doctoral thesis at the Johns Hopkins School of Hygiene 9 and Public Health Asbestos an Historical Case Study of Corporate Response to an Industrial 10 Health Hazard 1985 11 6. am the author of Asbestos Medical and Legal Aspects now in its fifth edition 12 2005 The first edition was largely identical to my doctoral thesis which is a major 13 authoritative treatise on state art My book has been relied upon by the scientific and 14 medical communities and cited as a learned treatise by a number of courts It is extensively 15 footnoted and annotated and is available in libraries and bookstores throughout the United 16 States It encompasses a comprehensive review of medical literature of all kinds as well as 17 other literature available in libraries and published sources such as government publications 18 safety magazines engineering journals trade magazines insurance publications encyclopedias 19 popular magazines and newspapers The doctoral thesis also involved research based on 20 unpublished government records The government records included workers compensation 21 claims files where claims had been made by individuals alleging that they had asbestos 22 diseases of the lungs claims against various companies that were their employers some of 23 which companies were also manufacturers of asbestos insulation products these individuals has 24 used in the course of their work I have also published many articles on the asbestos and 25 industry knowledge of asbestos related health hazards 26 7. Based on my studies and research I have formed the following conclusions A 27 sampling of relevant literature and reports is referred to after each conclusion 3 28 DECLARATION OF BARRY L CASTLEMAN Body of Knowledge that Exists A. Asbestosis 8. First let us consider what was available in published sources and how the published knowledge base developed The originally published reports in the era of the modern asbestos industry came at just before the turn of the century and the first reports in the English language were included in the annual reports of the chief inspector of factories and workshops in Great Britain The reported published in 1899 the report for the year 1898 talked about the observation of lung disease in individuals who had worked in asbestos manufacturing plants and about the evil effects of asbestos dust 10 9. The medical literature of asbestos disease mainly developed after the publication of a 11 case report in the British Medical Journal by Dr. Cooke a pathologist in Britain in 1924. This 12 was called Fibrosis of the Lungs Due to the Inhalation of Asbestos Dust Dr. Cooke reported 13 on the death of a year woman who had worked off and on in asbestos plants from the age 14 of 13. According to Cooke the scarring of her lung tissues was largely attributable to the 15 inhalation of asbestos in the course of her work There followed a number of other reports in 16 British sources and this is reflected as well in the United States in editorials of the Journal of 17 the American Medical Association In one on January 14 1928 called Pulmonary 18 Asbestosis reference is made to Cooke's case and other reports on the disease now called 19 asbestosis The Journal of the American Medical Association recommended that further 20 attention be paid to this disease as it may well be occurring in the United States The Journaolf the American Medical Association issued another editorial in 1930 about asbestosis this time 22 noting the asbestosis had become a compensable occupational disease in Great Britain under the 23 workers compensation law The Journal of the American Medical Association was believed to 24 have been read by 80 of American physicians in those years medical historians have written 25 10. In the meantime there were additional reports of asbestosis published in the British 26 Medical Journal which is in every medical library I have ever walked into The reports mainly 27 involved deaths of individuals who were verified as having asbestosis by autopsy 4 28 DECLARATION OF BARRY I. CASTLEMAN 11. In 1930 a report was published by a physician Dr. E.R.A. Merewether and an 2 engineer named C. W. Price Merewether and Price reported a survey that had been conducted 3 by the Factory Inspectorate in England including 363 asbestos workers who were actively 4 employed Of these individuals 26 were found to have asbestosis Merewether and Price 5 reported that the people longest exposed had the highest prevalence of the disease 80 in 6 workers with 20 years or more in the industry There were no cases of asbestosis in individuals 7 with less than five years and Merewether referred to that phenomenon that the disease was 8 delayed in appearance and developed gradually over a period of years It could in seven years 9 be substantially developed in the most severe cases but more often 11 years or more would 10 elapse before the disease had become largely developed in exposed individuals This is the time 11 from the onset of exposure Merewether urged that workers be educated to a sane appreciation 12 of the risk to health posed by asbestos dust Merewether's 1930 writings on asbestosis are 13 among those most often cited in the literature on asbestosis 14 12. There were reports also of the progression of disease caused by asbestos fibers 15 trapped in the lungs including a report by the radiologist Sparks called Pulmonary 16 Asbestosis published in the United States in 1931. Sparks talked about the fact that the 17 disease progressed in some individuals after the cessation of exposure This was demonstrated 18 by the chest rays of the individuals who had been removed from exposure but who had 19 continued to go downhill in terms of their lung conditions 20 13. There are also publications by Dr. Harold Stewart whom I mentioned and his 21 coworkers in 1931 describing two cases of asbestosis in the Archives of Pathology published 22 in the United States One of these individuals had been exposed for only nine months to 23 uncontrolled asbestos dust conditions and nine years later had developed a severe degree of 24 asbestosis when seen at autopsy 25 14. Other sources were also remarking on the disease asbestosis A journal called 26 National Underwriter a publication of the insurance industry in a 1932 article called 27 Occupational Diseases are Not Generally Understood repeatedly called attention to 28 S DECLARATION OF BARRY I. CASTLEMAN asbestosis and referred to asbestos industries as dangerous industries from the standpoint of 2 insurers who might be prevailed upon to sell coverage of various kinds for the health of workers 3 in such industries 4 15. In this connection I would mention that back in 1918 there was a United States 5 publication authored by Frederick Hoffman called Mortality from Respiratory Diseases in Dusty Trades This made reference to the annual reports of the Chief Inspector of Factories in 6 England and the reports of asbestos disease there This 1918 report written by an insurance 8 company actuary noted that it was the practice of American and Canadian life insurance 9 companies to not sell life insurance to asbestos workers on account of the assumed deleterious 10 conditions in the industry 11 16. By 1932 there were 60 or more publications in print on asbestosis These were noted 12 by way of reference in a bibliography published by the International Labor Organization in 13 1932. These publications continued to emerge from many countries The first cases of 14 asbestosis in the United States were reported in 1930. Asbestosis was also described in an 15 article in the trade magazine Asbestos in the United States in the March 1930 issue amid 16 numerous advertisements from asbestos mining and manufacturing companies 17 17. In 1932 the first case of asbestosis in an asbestos product user was reported at a 18 conference held by the Industrial Commission of Wisconsin proceedings of which were 19 published Here Dr. Albert Russell of the United States Bureau of Mines described an 20 individual who had worked maintaining the insulations on pipes in a government hospital and 21 had been diagnosed as having asbestosis and had been compensated by the government for 22 disability sustained from this asbestos condition This is the first published product user case 23 There were other cases reported in the United States in 1933 by Philip Ellman and also reported 24 by Ellman in 1934 in The British Journal of Radiology Wood and Gloyne reported in 1934 25 reported on cases of asbestosis including a boiler riveter who would have been exposed to 26 asbestos because it was used as an insulation material on boilers Wood & Gloyne's report was 27 called Pulmonary Asbestosis A Review of 100 Cases That was published in The Lancet the 6 28 DECLARATION OF BARRY I. CASTLEMAN 1 world's oldest medical journal in 1934. The Lancet is like the British Medical Journal a general medical journal published in England and available very widely in medical libraries in 3 the speaking world This article was widely cited in subsequent literature Of the 4 hundred cases of asbestosis they reported on the shortest duration of exposure in any case was 5 six months in the case of two women who had worked in an asbestos plant 6 18. In 1933 and 1934 in the British journal Tubercle Dr. Merewether published A 7 Memorandum on Asbestosis He emphatically noted that asbestosis shortened people's lives 8 Merewether showed that in the British experience individuals who had died with silicosis 9 another occupational lung disease had an average age at death of 54. In the case of asbestosis 10 the average age at death was only 41. The duration of exposure was similarly very much 11 different In the cases of silicosis in which death occurred the average duration of exposure 12 was 40 years For asbestosis the average duration of exposure was only 15 years 13 19. In 1935 the Pennsylvania state authorities published a report on asbestosis in the 14 industry in the state This was called Asbestosis published by Fulton and his coworkers at the 15 Pennsylvania Department of Labor and Industry fourth of the workers they examined had 16 asbestosis They included an impressive bibliography of 125 references to asbestos 17 disease previously published in journals in the United States England France Italy Germany 18 and other countries The Pennsylvania study included an effort to relate dose and response The 19 authors had sampled the exposure of the workers to dust in four asbestos plants and the found 20 that overall average concentrations of dust could be broken down into three groups that varied 21 from 4.64 million particles per cubic foot up to 44 million Asbestosis was reported in all three 22 groups with the prevalence and severity of disease greater in the more heavily exposed groups 23 But no level of exposure was found to be free of the disease This was one of the first surveys 24 of this kinidn the United States similar to that which had been done by Merewether and Price .25 and published in Great Britain and the United States separately in 1930. In all of these studies 26 at least 25 of the workers were diagnosed as having asbestosis 27 7 28 DECLARATION OF BARRY I. CASTLEMAN 20. The study by Lanza and his coworkers at Metropolitan Life published in 1935 and initiated at the request of representatives of the asbestos industry found that 53 of the workers 3 examined with three or more years of exposure had asbestosis 4 21. In 1938 a similar study was done by the Public Health Service including an effort 5 to account for workers who had been discharged before the Public Health Service was admitted 6 to the North Carolina asbestos textile plants to do the study An estimated asbestosis rate in the 7 workplace was given as 27 % The report recommended that dust exposure in asbestos 8 plants be limited to 5 million particles per cubic foot This guideline was recommended as a 9 tentative occupational exposure limit though it was noted that the Pennsylvania study had 10 found cases of asbestosis at that level of exposure 11 22. Literature on asbestosis was substantially developed by 1935. The disease was 12 shown to have a distinctive pathological appearance with asbestos bodies types of scarring that 13 would form around the asbestos fibers trapped in the lung tissues This was commented upon a 14 great deal by pathologists in the 1920s The disease was shown to have an identifiable 15 radiological appearance on chest ray distinctly different from such diseases as TB and 16 silicosis The disease was also characterized by shortness of breath which would become more 17 pronounced as the individual became more seriously affected by the disease 18 23. The risk of the disease involved not only mining and manufacturing plant workers 19 but by 1935 it had come to include users of some asbestos products mainly insulation products 20 such as these used by insulation workers Also there were two reports on clerical workers in 21 asbestos manufacturing plants with 30 to 40 years of experience and these individuals were 22 among the victims of asbestosis described in the medical literature published in Britain and the 23 United States in 1934 and 1935 24 24. The disease was consistently found to affect a large percentage of people who were 25 employed in the industries where asbestos products were manufactured This was reported in 26 four surveys in the United States and Britain by the mid to late 1930s 27 8 28 DECLARATION OF BARRY I. CASTLEMAN 1 B. Lung Cancer 2 25. In 1935 another aspect of the hazard of asbestosis was identified with the 3 publication of medical case reports of asbestosis in combination with lung cancer The first 4 such reports were published by Lynch and Smith in the United States in 1935 in the American S Journal of Cancer and by Dr. Gloyne in Great Britain in Tubercle in two separate reports in 6 1935 and 1936. In these reports the question was raised that chronic irritation of the lung 7 tissues from asbestos might be producing cancer as well as lung scarring already well identified 8 as an asbestos phenomenon 9 26. There were additional reports of lung cancer in combination with asbestosis reported 10 by Egbert and Geiger at Yale in 1936 and Nordmann in 1938. An abstract of this last publication appeared in the United States in the Journal of Industrial Hygiene & Toxicology also in 1938. The article was entitled The Occupational Cancer of Asbestos Workers The German author Nordmann concluded that asbestosis was definitely related to lung cancer that 10 lung cancer was in fact an occupational disease of asbestos workers Various features of the six 14 cases Nordmann knew of were tabulated to justify that Nordmann noted among other things that the prevalence of lung cancer among autopsied victims of asbestosis was one in six both in Germany and Great Britain This was very much higher that the prevalence of lung cancer in 18 18 2020 2211 22 223 2 24 24 2525 26 26 2828 the general population which tended to be more like % or several percent at most The high rate of lung cancer among people dying with asbestosis would be a most consistent finding around the world 27. There were additional publications of cases of lung cancer and asbestosis in 1939 in United the States and in 1941 and 1942 in Germany Holleb and Angrist reported in the American Journal of Pathology on two individuals who had been pipe coverers users of asbestos products diagnosed at autopsy as having both asbestosis and lung cancer These were the first cases of cancer and asbestosis in users of asbestos products published in the medical literature Holleb and Angrist tabulated a total of 10 cases of lung cancer in combination with asbestosis that had been published in the United States Britain and Germany This gave 9 DECLARATION OF BARRY I. CASTLEMAN readers of their articles the benefit of a review of what had come up until that time in worldwide 2 literature on lung cancer and asbestosis This was a feature of many medical articles on 3 asbestos disease that is they make extensive reference to preceding work So that if one finds 4 a single article one has the windows open on a great deal ofknowledge that preceded it 5 28. In 1942 Dr. Wilhelm Hueper published a book on occupational cancer called Occupational Tumors and Allied Diseases nearly 900 pages long It included a lengthy section 6 an on asbestosis and cancer from asbestos in which a large number of references from the United 8 States Great Britain and Germany were cited in support of the view that asbestos most likely 9 did cause occupational cancer Dr. Hueper made unequivocal statements the next year in the 1010 1111 1212 1313 1414 article called Cancer in its Relation to Occupational and Environment published in the Bulletin of the American Society for the Control of Cancer There Hueper said that asbestosis cancer of the lung as he called it then was the newest proved occupational cancer of the lung to be listed with the ones that were already known up at that time In the Journal of the American Medical Association JAMA there appeared an editorial called Environmental Cancer in 1515 1944 in which asbestos was listed among agents known and suspected of causing occupational 1616 cancer 1717 29. By 1950 there were more than 80 articles and abstracts referring to the lung cancer 18 18 hazard of asbestos including writings in newspapers and popular magazines see D below 1919 2020 2121 2222 2323 2424 2525 2626 C. Mesothelioma 30. The disease mesothelioma of the pleura was attributed to exposure to asbestos or asbestosis starting in 1943 with the report of Dr. H.W. Wedler in Heidelberg There were additional reports in the German literature as well as British literature The case reports that appeared prior to 1960 are annotated and cited by way of reference in Chapter 2 table 5 of my book Dr. Wedler was the first to state that he believed the pleural cancers were occupational cancers and his work was prominently cited in the United States in the 1940s Other German pathologists starting with Leicher in 1954 would identify peritoneal mesothelioma as an 2727 asbestos disease 2828 10 DECLARATION OF BARRY I. CASTLEMAN 31. A major report of pleural mesothelioma came from South Africa by Wagner and his 2 coworkers published in the British Journal of Industrial Medicine in 1960. Within a very short 3 time it was widely accepted that asbestos did cause mesothelioma that levels of asbestos 4 exposure present from environmental exposure as well as occupational exposure were sufficient 5 to cause mesothelioma and that mesothelioma was affecting a considerable number of workers 6 in shipyards Reports such as those in the British Medical Journal in 1962 described the 7 different types of workers who were being affected by mesothelioma in shipyards 8 32. In 1964 Dr. Irving Selikoff and his coworkers published a mortality study in JAMA 9 showing that there was a substantial excess of occupational cancer and deaths from asbestosis among people involved in the insulating trades A group of workers who installed insulation 11 and removed it regularly was found to have 45 deaths from pulmonary cancer in a group where 1312 only six or seven such deaths would have been expected There were four deaths from 13 peritoneal and pleural mesothelioma in this cohort and this was described as a very rare disease 14 and a substantial excess over what would have been expected There were also 12 deaths from | asbestosis in this work force 1616 33. Subsequently later in 1964 at an international conference held in New York and 17 published in 1965 Selikoff and coworkers reported that around % of the people who were in 1718 the insulating trade had developed asbestosis by the time they had been in trade for 20 or 30 19 years or more At the conference in New York British researchers Newhouse and Thompson 2020 presented a report on 76 deceased mesothelioma patients and an equal number of controls 2121 based on interviews with relatives Their report showed strong evidence that mesothelioma 222 patients were far more likely to have had occupational household or neighborhood exposure to 2233 asbestos than the comparison patients who died from other causes at the same hospital 2244 2525 2266 D. Other Sources of Knowledge 34. The subject of asbestosis was receiving attention in other types of circles The Encyclopedia Britannica first noted the disease asbestosis in the regular publication of the 2727 Encyclopedia in 1940 2288 11 DECLARATION OF BARRY 1. CASTLEMAN 35. By this time The National Safety Council had been established for 28 years as 2 management's response to the industrial safety issue with its associated problems of disability 3 compensation and labor unrest Starting in the 1930s the National Safety Council has published 4 numerous articles pamphlets and other materials concerning the hazards of asbestosis in the 5 1930s Many of the annual congresses held forums and discussions about dust disease The 6 transactions of these meetings were automatically mailed to the industrial members 7 36. During the 1930s there were an increasing number of lawsuits for dust diseases 8 contracted in the workplace To confront this dust disease threat a meeting of about 250 people 9 representing over 50 industries with industrial disease problems was held on January 15 1935 10 The meeting covered the hazards of asbestos and silica dust and one focus of the meeting was 111 on the menace of ambulance chasing lawyers in combination with unscrupulous doctors 12 During this and subsequent meetings of the association which was initially called the Air 1133 Hygiene Foundation lawyers outlined a plan to limit dust disease lawsuits and compensation 1144 This included eliminating the right to trial and limiting workers ability to claim workers 15 compensation 1516 37. The refractories industry played a major role in this meeting and subsequent 17 establishment of the Air Hygiene Foundation renamed the Industrial Hygiene FoundationFoundation in 1818 1941 As chairman of the Temporary Organizing Committee Mr. Hitchens of the American 1199 Refractories Institute oversaw much of the planning of the structure and outline of purposes of 2200 the organization Through Industrial Hygiene Foundation publications meetings and 2211 conferences its members have been long aware about dust diseases and the responsibilities of 2222 manufacturers to warn concerning hazards associated with their products 2233 38. Among the means by which the Industrial Hygiene Foundation disseminated 2244 information was the Industrial Hygiene Digest which published abstracts of articles from 25 hundreds ofjournals that were being published The Industrial Hygiene Digest included 225 6 abstracts of industrial medicine articles that had appeared in the journals included reference to 2727 cancers of the lung and pleura reported originally by Dr. Wedler in 1943 in January of 1945 2288 12 DECLARATION OF BARRY I. CASTLEMAN Wedler's article had been published in the German Medical Weekly Here we see the first 2 references to cancers of the pleura as well as cancers of the lungs all being counted as 3 pulmonary asbestos cancers in literature 4 39. In 1944 a trade magazine called Heating and Ventilating carried an article called 5 Dust is an Industrial Health Hazard by Hutchinson in which was noted that fatal cases of 6 asbestosis occurred in shorter periods of time than fatal cases of silicosis and also that the 7 hazard of asbestosis extended to industries including the insulating industry Hutchinson said at 8 that time there was no known safe level of exposure 9 40. The Journal of the American Medical Association carried an editorial called 10 Asbestosis and Cancer of the Lung in August of 1949. This reported British statistics on 235 11 deaths in which asbestosis had played a part Of these 235 31 % of the individuals were 12 also found to have cancers of the lung or pleura This was considered quite excessive compared 13 to the normal rate of lung cancer in the general population of % of all autopsies This editorial 14 in the Journal of the American Medical Association was promptly summarized in the abstract 15 form in the Industrial Hygiene Digest in 1949 16 41. Reference to cancer from asbestos appeared in the New York Times on Jan. 7 1948 17 Business Week Nov. 13 1948 Washington Post Nov. 21 1948 and Scientific American in 18 January 1949 in an article called Cancer and Environment It appeared in Newsweek 19 magazine May 15 1950. The reference to asbestos in Newsweek was in relation to the rising 20 rate of lung cancer in urban dwellers compared with people in the rural areas This was partly 21 attributed to the presence of carcinogens like asbestos in urban air according to Dr. Hueper 22 Chief of the Environmental Cancer Section US National Cancer Institute The Los Angeles 23 Times noted the carcinogenicity of asbestos April 6 1951 the Chicago Tribune on June 10 24 1951. The Encyclopedia Britannica made reference to asbestos as one of the causes of 25 occupational cancer under the title cancer in 1952 and asbestos was described as a lung 26 cancer hazard to steamfitters working with asbestos in the Wall Street Journal on April 7 1959 27 13 28 DECLARATION OF BARRY I. CASTLEMAN 42. The Engineering Index was first available in 1883. This index contains made trade journals and leans toward engineering applications rather than general interest or basic chemical research Another source of technical and medical information is the Bibliographic Index which 4 was first published in 1945 by the H.W. Wilson Company and covers the years beginning with 5 1937. This index lists bibliographies and thus could be used as a source of accumulated 6 references The bibliography sources are listed under subject headings arranged alphabetically 7 Examples of headings in these indexes in a search on the health effects of asbestos include 8 Asbestos Dust Workmen's Compensation Diseases Industrial Hygiene and Pneumoconiosis 9 The technology indexes were useful in locating articles on asbestos in U.S. trade publications 10 43. Additionally an enormous collection of information was available from U.S. 11 government sources NIOSH has issued Current Intelligent Bulletins since 1975 these have 12 included hazard alert notices on asbestos and other occupational health hazards Prior to the 13 establishment of NIOSH under the Occupational Safety and Health Act of 1970 a predecessor 14 agency existed the Bureau of Occupational Safety and Health which was also within the U.S. 15 Public Health Service PHS in the Department of Health Education and Welfare Reports on 16 occupational health hazards were published by the PHS in Public Health Bulletins 1881-1949 17 and continued as Public Health Monographs 1950-1971 Notable among these on the subject 18 of asbestos were Bulletin No. 241 by Dreesen et al 1938 and Monograph No. 36 by Hueper 19 on lung carcinogens 1955 Other subjects covered by these reports include Bulletin No. 208 20 Health of Workers in Dusty Trades 1933 Bulletin No. 238 Cement clay and pottery 21 industries 1937 Bulletin No. 260 Illness among workers and housewives 1941 Bulletin No. 22 267 Lead arsenate exposure of orchardists and consumers 1941 etc. Some of these files are 23 still retained and are known as the historic toxicology files They were located in the Cincinatti 24 offices of NIOSH and the American Conference of Governmental Industrial Hygienists 25 ACGIH 26 44. The United States Environmental Protection Agency has been in existence since 27 1970 and it primarily regulates air pollution water pollution and land disposal of industrial 14 28 DECLARATION OF BARRY I. CASTLEMAN wastes The EPA has supported much research into the potential hazards of asbestos in drinking 2 water The EPA also calls upon the National Academy of Sciences for reports on the state of 3 knowledge about health risks to the general public from environmental asbestos exposure 4 Asbestos Needfor and Feasibility of Controls 1971 Drinking water and Health Volume 5 1 1977 pp 144-168 and Volume 5 1983 pp 123-147 and Asbestiform 6 Nonoccupational Health Risks 1984. In 1973 the EPA issued the National Emission 7 Standards for Hazardous Air Pollutants Fed Register Apr. 6 1973 amended Oct. 14 1975 8 These regulations curtail asbestos use in sprayed and molded insulation ban visible emissions 9 from asbestos mills and manufacturing plants and waste dumps regulate demolition of 10 buildings containing asbestos and ban use of asbestos mine tailings for surfacing roads 11 E. TLVs 12 45. Various guidelines have been recommended to limit asbestosis as a hazard in places 13 where asbestos is used These guidelines included called Threshold Limit Values TLVs or 14 maximum allowable concentrations The Public Health Service in its survey in 1938 15 recommended 5 million particles per cubic foot for dust in which asbestos was present in the 16 workplace as a ceiling concentration This was adopted by governmental group a 17 volunteer professional organization It was recommended as a guideline in some states prior to 18 the enactment of the Occupational Safety and Health Act in 1970 took 19 46. Authors in other countries issue with the idea that one could recommend an 20 occupational exposure limit of dust in the air and thereby completely control health hazards 21 Under the heading The Prevention of the Dust Disease Dr. McLaughlin of the Factory 22 Inspectorate in Great Britain writing in The Lancet in 1953 said that people in some countries 23 who recommend these maximum allowable concentrations seem to think that man is a 24 standardized machine which he clearly is not McLaughlin noted a number of factors that 25 would distinguish people in terms of their risks in ways that we could recognize as well as the 26 fact that there are also ways that we can't recognize where one individual exposed to the same 28 things as another working right next to him gets sick and the other one does not 15 28 DECLARATION OF BARRY I. CASTLEMAN 47. Others such as that of Dr. May Mayers of New York in 1952 and Warren Cook 2 also writing in the United States in 1956 observed that maximum allowable concentrations that 3 were recommended to prevent other effects than cancer could not be considered to be safe if the 4 substances also caused cancer Asbestos was noted by both of those authors as one such 5 substance that caused cancer 6 48. The Documentation of the Threshold Limit Values published in 1962 and in its 7 second edition in 1966 clearly indicated that the asbestos TLV was based on the 1938 Public 8 Health Service study and was only suggested to protect against the disease asbestosis The 9 word cancer was not even mentioned in the 1966 Documentation whose most recent cited 10 reference on asbestos was dated 1955 11 49. With asbestos as with many other substances it was infrequent that the TLV or the 12 basis for them were reviewed in the light of recent literature once the substance was on the list 13 The limited efforts of unpaid volunteers working on the TLV committees appear to have been 14 mainly devoted to adding new substances to the list during the 1950s and thereafter 15 F. Product Users 16 50. There were many articles coming out in the 1940s and 1950s that noted the risk of 17 asbestosis and in some cases cancer in individuals who were exposed to asbestos in the course 18 of using containing products there were more than 50 separate case reports some 19 involving one or two individuals some involving as many as ten or more These case reports 20 were published mostly in the English language in medical journals between 1932 and 1963 21 These reports are tabulated in Chapter 5 Tables 2 and 3 in my book Asbestos Medical and 22 Legal Aspects 23 51. Companies marketing products that could give rise to respirable asbestos dust either 24 were or should have been aware that most dusts can either cause or aggravate problems in the 25 lungs of product users Some specific company knowledge includes the following 26 Westinghouse's medical director wrote a book in 1947 in which he state that asbestos produced 27 serious effects including the progressive disease of asbestosis yet the company did virtually 16 28 DECLARATION OF BARRY I. CASTLEMAN nothing to warn users of its products until required to do so by federal regulations Mine Safety Appliances Company published several pamphlets outlining the problems associated with dusts 2 and recommending the usage of respirators yet did not put warnings on its asbestos clothing In 4 1964 Picher told GREFCO and NARCO that it was putting warning labels on the 5 asbestos products it manufactured for them but neither company put warnings on its own 6 manufactured asbestos products These are but a few examples of widespread failure to warn 7 workers concerning the hazards associated with asbestos and other dusts 8 G. Household Contact Asbestos Exposure and Disease 9 52. In 1897 the first physician in modern times to write about lung disease in asbestos 10 workers also commented on ill health among the workers family members The families of 11 asbestos workers in the 20th century were exposed to asbestos brought home on the 12 clothes shoes hair tool boxes lunch boxes and automobiles of the workers 13 53. As far back as 1913 the text Safety by W.H. Tolman and L. B. Kendall p 249 _ 14 emphasized the importance of having workers remove work clothes before leaving a factory 15 where toxic materials are handled so the poisons would not be carried into the homes of 16 workers 17 54. Some chemical companies provided work clothes and laundered them in plants using 18 toxic and carcinogenic chemicals as early as the 1920s compartment lockers or 19 preferably two individual lockers should be provided in dressing rooms for employees whose 22 clothes are exposed to poisonous material said the U.S. Public Health Service in the Manual of 21 Industrial Hygiene 1943 An article that year in the trade magazine Chemical Engineering 22 advised separate lockers for street clothes and work clothes separated by showers in plants 23 handling aluminum powder Hueper wrote in JAMA in 1946 that workers handling 24 carcinogenic materials such as asbestos be provided with showers and special rooms for storing 25 street clothes 26 55. Corporate physicians advised a number of safeguards that would have protected 27 families of workers at a Chrysler plant being built in 1946. The plant was to use asbestos and 17 28 DECLARATION OF BARRY I. CASTLEMAN I chemicals that could cause toxic effects and dermatitis Protective clothing laundry showers 2 and separate lockers for street and work clothing were recommended by the doctors In a 1948 3 document Roy S. Bonsib an industrial hygienist for Standard Oil of New Jersey stated 4 Appropriate work clothes properly fitted and maintained play a prominent part in an 5 industrial worker's health and efficiency This is especially true when persons are working with 6 more or less toxic or carcinogenic materials or where cleanliness is a factor in the maintenance 7 of product quality Consequently many of the more progressive industrial organizations such 8 as E.I. DuPont de Nemours & Company the American Cyanamid Company and the Borden 9 Company have for years supplied their employees with work clothing and have instituted a laundry service 11 56. A 1951 article Industrial Hygiene in the Paint Factory in the trade magazine Paint 12 and Varnish recommended the provision of work uniforms not to be worn home and separate 13 lockers for work clothes and street clothes 14 57. The United States Department of Labor issued safety and health guidelines in 1615 conjunction with contract work for the federal government A 1952 document entitled Safety 16 and Health Standards for Contractors performing Federal Supply Contracts under the Walsh- 17 Healey Public Contracts Act required that contractors provide facilities to prevent the 1718 communication of harmful substances from work clothes by contact to street clothes 19 Subsequently Walsh Healey regulations were published in the Federal Register in 1960. These 2020 regulations provided that Where employees work clothes are exposed to contamination by 2121 poisonous infectious or irritating material facilities shall be provided in change rooms so that 2222 street and work clothes will not be stored in contact with each other 2323 58. Retired Monsanto chemist and industrial hygienist Jack Garrett has testified that in 2424 the 1950s that chemical company's employee protection against asbestos from insulation 2525 products included showers and daily changes of clothes We went down to shoes and socks 2626 underwear and all We didn't want it at home deposition in Schmidt District Court of 2727 Jefferson Co. TX Dec. 16 1993 In 1967 Shell Chemicals in Britain adopted a code of 2828 18 DECLARATION OF BARRY I. CASTLEMAN 1 practice for handling asbestos products including vacuum hoses for removing dust from 2 clothing and shoes separate lockers for work clothes and street clothes and hot and cold 3 showers Work overalls were vacuum cleaned bagged with warning labeling and laundered by 4 the company 5 59. The Occupational Safety and Health Administration OSHA was created by 6 Congress in the last days of 1970. In June of 1972 OSHA asbestos regulations were published 7 in the Federal Register containing rules for laundering of contaminated clothing 8 60. The hazard of asbestos exposure to families of the workers in particular cancer was 9 scientifically knowable long before it was studied directly as illustrated by the advice of the Chrysler doctors 61. Once it was substantially established in the 1940s that asbestos exposure could cause 12 lung cancer the consequent public health impact of asbestos use was dramatically increased Cancer is initiated by the malignant transformation of a single cell which replicates itself until it 1 threatens the life of the affected person This meant that asbestos exposures insufficient to cause 16 death from asbestosis could clearly cause death by cancer This had been recognized by German workers compensation authorities in establishing workers compensation recognition to lung cancer as occupational in the presence of slight " asbestosis as early as 1939 Baader Asbestosis German Med Weekly 65 407-408 1939 The danger of occupational 19 asbestos exposure as a cause of lung cancer was noted by Dr. Wilhelm Hueper Chief of the 20 Environmental Cancer Section of the US National Cancer Institute in warning in 1950 that 221 urban air pollution including carcinogens such as asbestos was a factor in the rising incidence of 22 lung cancer in the general population Environmental Cancer Hazards Caused by Industrial Air 22 33 Pollution Arch Ind Hyg Occ Med 2 325-328 1950 Small Studies Newsweek p 53 May 24 15 1950 2524 62. It followed that whatever exposure limits that were considered applicable to limit 2626 cancer effects of a substance were in no way to be considered protective if the substance 27 also caused cancer Experts considering this in the 1950s recommended that for a nickel 2828 19 DECLARATION OF BARRY L CASTLEMAN compound believed to be carcinogenic the occupational exposure limit should be lowered by a 2 safety factor from 500th to 100th the exposure level that would have applied for other 3 types of systemic injury the substance caused H. Stokinger Prepared Discussion Am Ind 4 Hyg Assoc Quarterly 17 284-286 1956 63. And it also follows that if a substance is a carcinogen the population at risk from its 5 6 use in society has to be broadened to consider environmental exposures such as air pollution 7 consumer product use and contamination of workers homes by carcinogenic dust brought 8 home on the clothes hair shoes lunchboxes and cars of the unsuspecting workers This is 9 particularly true in the case of asbestos a chemically stable solid 10 64. Industry was well aware that asbestos was mineral with high resistance to destructive 11 forces such as heat and that asbestos did not decompose even upon prolonged storage One 12 scientist borrowed from the language applied to radiation in stating that asbestos in the 13 environment had a half of infinity It was also obvious that absent any safeguards to 14 prevent it workers typically exposed to dust from asbestos products would take the contaminant 15 home on them where it would accumulate in carpets clothing window curtains and furniture 16 It was also known that the very young the developing organism would be most susceptible to 17 the action of carcinogenic agents a fact demonstrated in laboratory testing of carcinogenic 18 agents at least as far back as 1938 cited in Hueper Occupational Tumors and Allied Diseases 19 1942 p 758 that asbestos 20 65. Companies that were or should have been aware was carcinogenic 21 should have anticipated that allowing workers to return home unwarned with causing 22 dust all over their clothes etc. would have also endangered the lives of their family members In 23 the 1950s the type of cancer most associated with asbestos was lung cancer The additional 24 widespread recognition that asbestos also caused mesothelioma which was in fact a signal 25 tumor for asbestos exposure made it possible for epidemiologists and others to confirm that the 26 cancer hazard of asbestos had indeed spread into the homes of the workers and the 27 neighborhoods of asbestos air pollution point sources 20 CASTLEMAN 28 DECLARATION OF BARRY I. 1 66. Studies on the occurrence of asbestos disease that included family members of 2 asbestos workers were not published until the 1960s and work such as that of 3 Newhouse and Thompson 1965 and Lieben and Pistawka 1967 established that 4 mesothelioma was causing deaths among persons with only household and not occupational S exposure to asbestos The contamination of workers homes and the exposure of their spouses 6 and children was very foreseeable and with the knowledge that asbestos was carcinogenic came 7 the possibility that household exposures could have disastrous consequences for 8 members of workers families if not prevented 9 H. W.R. Grace and Vermiculite from Libby Montana 1010 67. In 1954 W.R. Grace & Company bought Dewey & Almy Chemical Co. which had 1111 made asbestos brake linings before it closed its Multibestos plant in Massachusetts in 1936 12 Bradley Dewey the company's president was interested in the subject of asbestosis and 13 corresponded with a state official and others about it in the 1930s His company had numerous 1214 workers compensation claims brought against it by employees of the Multibestos plant and 15 some of the plant worker asbestosis cases were reviewed at the Saranac Laboratory in the mid16 1930s Vorwald Patient Files Nos 31-37 35-85 34-101 35-129 and 36-124 17 Armed Forces Institute of Pathology Washington D.C. 18 68. In 1963 W.R. Grace purchased the Zonolite Company which operated the world's 1919 largest vermiculite mines which were located in Libby Montana Zonolite made Mono 2020 fireproofing cement and containing acoustical plaster The Montana operation began 2121 mining in 1919 and in fact was originally called the Vermiculite and Asbestos Corporation both 2222 minerals were present in the deposit Large production began in the 1930s as vermiculite- 2323 expanding factories were built in Spokane Chicago and Detroit Initially the vermiculite was 2424 used only for insulation but in the 1950s it began to be used in concrete mixes as well 2525 69. In 1956 Montana State Board of Health industrial hygienist Benjamin Wake visited 2626 the Libby mine and mill and took atmospheric dust samples Total dust counts averaged 40 2727 MPPCF Company records stated that the dust was 8-21 asbestos Recommendations were 2828 21 DECLARATION OF BARRY I. CASTLEMAN made to management to improve dust control in the mill Conditions were still poor and dust 2 counts high when Wale returned to the site in 1958 1962 and 1963. A June 1961 letter from E. 3 Lovick assistant to the Libby plant manager to C.A. Pratt vice president of Western Mineral 4 Products Co. acknowledged that asbestosis was a matter of concern based on many studies 5 Montana's inclusion of occupational disease coverage in the workers comp law in 1959 was 6 accompanied by the company's decision to institute an employee ray program Doctors 7 reports which are said to have been inconclusive on the question of whether there was a lung 8 disease hazard in the plant stated that asbestos in concentrates shipped to vermiculite expanding 9 plants should give rise to very small amounts of it in the dust in expansion plants In an 10 September 1961 letter from Pratt to J.A. Kelley at Zonolite Pratt mentions that the Minneapolis 11 Health Department had expressed concern about dust in vermiculite plants 12 70. In 1965 W.R. Grace was discussing the presence of asbestos in Libby vermiculite 13 and reports of men having pulmonary trouble at Libby with Grant Industries See e.g. Feb. 14 9 1965 letter from O.F. Stewart WRG headquarters to N. Bushell Grant Industries A 15 March 1969 internal W.R. Grace memorandum advises use of warning labeling on products 16 containing vermiculite to aid in defense of product liability cases See Mar. 11 1969 17|| Memorandum from P. Kostic to R.W. Sterrett Attached to the memorandum was an article 18 referencing the introduction of an Asbestos Safety Bill in Congress and reports of 19 mesothelioma in household contacts of asbestos workers and neighbors of asbestos plants By 20 1977 there were internal discussions at W.R. Grace about the possibility of tremolite asbestos in 21 expanded vermiculite and that tremolite might be carcinogenic in the digestive tract of humans 22 or animals See Feb. 18 1977 Memorandum from H.C. Duecker to J Yang in reference to a 23 product called Verxite which was an vermiculite product sold as a food additive 24 for livestock and poultry feeds and dogfood see also July 14 1977 Memorandum from J.C. 25 Yang to H.C. Duecker noting a letter from Dr. William Smith stating that a 50-50 tremolite- 26 vermiculite combination injected into hamsters caused mesotheliomas 27 28 22 DECLARATION OF BARRY I. CASTLEMAN sameness 71. W.R. Grace did not close its vermiculite mining operation in Libby Montana until 2 1990. Grace was well aware that the tremolite asbestos that was part of the vermiculite ore 3 could give rise to hazardous exposures and warrant warning labeling 4 Edward Orton Jr. Ceramic Foundation's Actual or Constructive Knowledge 5 72. have reviewed the deposition testimony of plaintiff Roger Packett in which he 6 identifies a colored vermiculite packing material that came in the boxes of Orton 7 Pyrometric Cones that he and his wife decedent Donna Packett used in 1972 1973 1974 and 8 1981 as well as at other times I have also reviewed the declaration of Terry Spear and attached 9 exhibits including testimony and attestations by Edward Orton Jr. Ceramic Foundation 10 Orton corporate designee and former General Manager Gary Childress According to these 11 sources Orton was established in 1932 but it began manufacturing pyrometric cones decades 12 earlier Orton has manufactured and sold millions of its ceramic arts products in 70 countries its 13 peak sales were in the 1970s and 1980s Prior to 1963 Orton packaged its pyrometric 14 cones in saw dust Beginning in 1963 Orton began packaging its pyrometric cones in 15 vermiculite that it obtained from W.R. Grace Orton did not stop using vermiculite to package 16 its cones in until 1983. Orton is an based company and has its only manufacturing 17 facilities in Ohio 18 73. The Ohio Safety Congress was an annual meeting held under the auspices of the 19 Industrial Commission of Ohio since the 1930s After the meetinthge Proceedings of the Ohio 20 Safety Congress would be published by the Industrial Commission of Ohio and made publicly 21 available Attached as Exhibit 2 are examples of such publications from 1938 and 1940. In each 22 of those meetings the danger of inhalation of hazardous dust in the workplace was discussed 23 including resultant lung diseases such as pneumoconiosis silicosis and asbestosis 24 74. Additionally the Ohio Department of Health Division of Industrial Hygiene 25 promulgated regulations in 1946 for the prevention and control of diseases resulting from 26 exposure to toxic fumes vapors mists gases and dusts in order to preserve and protect the 27 public health These regulations applied to every place of employment " within the State and 23 28 DECLARATION OF BARRY 1. CASTLEMAN 1 particularly to those places of employment where a work or process is carried on by which 2 dusts fumes mists vapors gases or environmental conditions of a harmful nature are produced 3 or generated or exist independently of the work or process which may be inhaled or absorbed 4 or in any other manner enter the body in quantities or concentrations that constitute harmful S exposure defined as exposure that is injurious to the body See Exhibit 3 hereto As an Ohio 6 employer during the years when these regulations were in effect Orton was responsible for 7 protecting its workers from injurious dust in the workplace Orton could not have successfully 8 met this obligation if it did not undertake the research and investigation necessary to determine 9 whether toxic fumes vapors mists gases or dusts existed at its manufacturing facilities 10 10 75. In light of the information available to large manufacturers such as Orton throughout the 1950s 1960s and 1970s about the potential for asbestos to cause diseases 12 including cancers it is my opinion that Orton a major manufacturer and Ohio employer subject to regulations governing exposures to toxic dusts in the workplace could have known by the 1214 time it started purchasing vermiculite from W.R. Grace for use as packing material in its 15 pyrometric cone packaging that the vermiculite coming from Libby was contaminated with 16 asbestos and had the potential to cause grave harm to persons exposed to dust that might be 17 generated by the handling of this material By 1963 it was well established in the literature and 18 known by the asbestos industry and its major customers in various industries that asbestos 19 dust was toxic and carcinogenic In addition by the early 1950s it was recognized in the 2020 medical and scientific literature that individuals could contract asbestos diseases as a 2121 result of relatively low exposures to asbestos dust In September 1978 Orton was told by WR 22 Grace that WRG vermiculite contained tremolite asbestos In December 1978 Orton received 2223 an asbestos analysis report on vermiculite from another source demonstrating that Orton was 2424 aware of the possible contamination of vermiculite with asbestos and the means to 2525 independently verify whether or not such materials contained asbestos 2626 2727 2828 24 DECLARATION OF BARRY I. CASTLEMAN ye ay i Ree ee es a esBe 7 ae a