Document xzRJq8eR4NGLbJVbVZp1gaQxQ

Canadian Epidemiology Research Conference-1989 PLAINTIFF'S EXHIBIT DOW-1839 Conference Canadienne Sur la Recherche Epidemioiogique-1989 ABSTRACTS ST0I64U60 August 28-31, 1989 85 University University of Ottowa Wain Campus University Centre 28-31 Aout,J989 85 Universite' Campus Principal de rUniversife' d'OHawa Centre Universitaire OTTAWA, Ontario, Canada ABSTRACT AN HISTORICAL PROSPECTIVE MORTALITY STUOY OF THE SARNIA DIVISION OF DOW.CHEMICAL CANAOA INC. SARNIA, ONTARIO (1950-1984) (Egedahl RD, Olsen GW, Coppock E, Young ML and Arnold IMF) The mortality experience of 3,479 male Dow Canada employees who were employed at Sarnia Division for at least 12 continuous months during the years 1945 through 1983 was examined. Mortality ascertainment was obtained utilizing the Canadian Mortality Data Base maintained by Statistics Canada and covered the years 1950 through 1984. Cause-specific mortality analyses were accomplished using male, age and calendar-year adjusted death rates for Canada and the province of Ontario. Total mortality was observed to have been significantly below expectation whether the entire follow-up period (240 observed vs. 365.9 expected) or a 15-year latency period (171 observed vs. 290.4 expected) was considered. Statisti cally significant fewer observed deaths were found for all respira tory cancer, cancer of the bronchus and lung, circulatory disease, ischemic heart disease, cerebrovascular disease, digestive disease, cirrhosis and other liver disease and deaths due to accidents, poisonings and violence. The observation of three deaths due to mesothelioma, a rare cancer often associated with asbestos expo sure, was a significant finding as was a statistically significant elevation of observed deaths in the category "other forms of heart disease". I 9V l9 I 01S