Document xz9w9xzg6O8jGgggLwv6n6VKG

-Jfefc- Torier, -Chddfc '<*'Connell,' Staffs arid Regional Directors T Rogers DATE: November 20, 1985 KJ>'EfLENC - list: of Acute -Substances, a .. . ' Cherai calJteri&ehhy ;fdpafddhess Progrant, formerly Acute 'Hazards Attached is art article which appeared in the. November 20 New York Times which contains a list of 403 "very toxic.chemicals," Thisis nofsEPh's final official "lieit'OC-dien^cals which the agency is. preparing as a c@0i6heftt;'of its Chemical Emergency -Preparedness Program to aid cotniuni ties 4 rt developing programs to hscyil^ chemical! emergencies. EPA does not expect to^p^lish, its final list until late December, . 4'Ihe4rst weis apparently carpi led by the newspaper iron bits and pieces of iofonsatioh provided by someone within the government*, according to ;ths ffew York limesreporter*;' Even though it is not the..official.list," one sho^idJBe prepared for pufcrliO'Aiocus on substances found in the liste. There ape a number of substances-on the list, which can be foynd in. the plastics,industry, cxif. prijnary concern-would be the misuse of;the list. ^ You will note in the article that the limes created the categories using various resources. I will keep you apprised of further.developtnents on this issue. Enclosure cc: John Dubek THE SOCIETY OF THE PLASTICS INDUSTRY, INC. SPI-05511 MuRECEIV THE NEW YORK TIMES Wednesday, November 20, 1985 NOV 2 P1985 ^ Federal List of 403 Veryj.'foxTc Oi^nicals, With Effects on Human Health The following list, compiled by the Environmental Protection Agency, names 403 substances manufactured, used and stored in the United States that the agency says can pose an "im mediate threat to Ufe and health" in the event of an accident at a chemical facility. The agency has urged mu nicipalities to determine which com panies handle thstm and in what quan tities so that any excessive risks can be minimised. Breakdown into categories was done by The New York Times, based on chtmieat reference manuals and consultation with exports, who also supplied the description of toxic ef fects. Some chemicals overtop differ ent categories; the primary use or health effect was chosen. Acids--S Reactive, comwtve. Burn skin, eyes, nssni peteagee on contact. Chlcrbecetic add Hydrochkntc acid Hydrogen fluoride (hydrofluoric odd) Nitric add Sulfuric add . Cyanides--! Prevent oxygen absorption by the body; some ere very highly unde Some are used to make plastics; the finished product loses the toxicity. Others are used in extraction of metal from photographic films and ores. Acrylonitrile (vinyl cyanide) Adiponitrile Benzyl cyanide Cyanogen bromide Cyanogen iodide Formaldehyde cyanohydlzp Hydrocyanic acid (bydropn cyanide) Isobutyrorowle lictomtrile Mtiononitrile Meihacrylonitrlle Pouectum cyanide Focaasium stiver cyanide Proptonitrtle Proptooitrile, J-chioroSodiam cyanide Industrial Gases --17 Basic building blocks for many chemicals. Since they are already gases, they can rapidly spread be yond a plant fence after a leak. Arnmnia Arsine Bromine Chlerioe Diborane Fluorine Hydrogen selenjde Hydrogen sulfide Methyl mercaptan Nitric oxide Nitrogen dioxide Ozone Phosphine Sulfur dioxide Sulfur tetrefluoride Sulfur uloxide Tellurium hexafluoride Pharmaceuticals--25 such M^bacterta^m^tmaS'^dosM. Larger doaea art highly toxic to humans. Amphetamine SacitreciA C.I. basic green 1 (brilliant green) Cantharidia Carbachol chloride CotctUctoe Diptoxin Digoxin Dtthiazanine iodide Emetine dUrydrochioride Ergocalciferol (vitamin D) Ergotamine tartrate Fluorouracil Indcmethaein Mechlorethaunioe Mitomycin C Muacimoi Ouabain Phenylthiourea PhyUoquinooe (vitamin K) Pbysostigmioe Physoetigmine salicylate Picrotoxln Tns(2-chloreethyi)amine Valinomycin Chemical Intermediates--II Made from basic chemicals, used to produce more complex commer cial chemicals. Often much more toxic than finished chemicals. Acetone cyanohydrin Acetone thioaemicarbexide Acrolein Acrylyi chloride Aliy! alcohol Ally! amino Aniline Aniline, 2,t.StrimethyiBenzal chloride Benzenamine, Mtrifluoromechyl)Benzene, l-<chk>romihyl)-Hiitio. Benzenesuifonyl chloride Benzotrichloride Benzyl chloride Bis(chh>romethyl)ketone 2-Butene, 1.4-dichioro-.(ElButyl vinyl ether Chloroscetaldehyde Chloroethenol Chloroethyl chloroformate Chiorometbyl ether Chioromethyt methyl ether Cresylic acid Crotonaldehyde Cyanuric fluorida Cyclohexylaaine Dlchlonrethyl ether DtchloiomethylphenylsilaiM Diethyi-p-phenyMaedlamine Diglyddyi ether Dimethyl suifete Dimethyl sulfide Dimethyt-p-phenylenedlamine Diozolane FdrKtftfii*Mn4pIy> m Ethaneeulfonyl chloride, 2-chkmEthanol, ljdlchiom-, acetate Ethyl thiocyanate Ethylroedlamtne Ethylene fluotohydrin Ethylene imtne Ethylene oxide Fluorecetyl chloride Formaldehyde Furan Henmethylenadiamin*. NJf'-dibutyiHydnzine Hydrogen peroxide HydjnquuMot Isocyanle add. l.adichlorphenyi ester Isopropyl chloroformate Mesitylene Methscrolein diacetats MethacryUc anhydride Meihacryloyt chloride Methanesulfonyl fluoride Methyl chloroformate Methyl disulfide Methylhydrarine Methyl isocyanate Methyl Isothiocyanate Methyl phosphonic dichloride Methyl thiocyanate Nitrobenzene Nitrocyciohexane Pencadecytamine Phenol Phenyihydrazine hydrochloride Phosgene Phosphorous trichloride Phosphorus Phosphorus oxychloride Phosphorus pentachloride Phosphorus pentoxide piperidine Propargyl bromide Propnoiaetone. betaPropyl chkxoformste Propylene imine Propylene oxide Pseudocumene Selenium oxychloride Selenous add Semicarbezide hydrochloride Sodium leienate Sodium selenite Sodium tellurite Thiocarbezide Thiopheoot Thioaemicarhezide Trlchlormcetyl chloride SPl-05512 THF NEW YORK TIMES Wednesday, November 20, 1985 (Cont'd.) Pesticide Compounds--147 Designed to kill target organisms in small doses. Harmful to humans in large doses. Aldicarb Aldrin Aluminum phosphide Aminopcerin Amitoo Amiton oxalate Antimydn A Antu Arsenic pentoxide Arsenous oxide Arsenous trichloride Azinphoe-ethyl Annphoe-methyl Bitoscanate BromadMone Calcium aroenata Caaphschlor Carbofunn CarbopbanotUoa Chlordans Chlorfanrinfoa Chtonnephos ClUormaquat chloride t-exo-OUarvS-ndo-cyaiioJ-nortoRias- one 0-fmethyicajtdmoyt)oxime Chtoropbaclnone Chloroxuron Chlorthioptes Coumafuryl Coumaphos Coumatetraiyl Crimidina Cyanophoa Cydohaximide Demeton Demeton-S-methyl Dialifos Dichlorobenalkoniua chloride Dichlorvos Dicrotophoe Diepoxybutane Diethyl chlorophoephate Dtethylcarbamaztne atrite Dimefax Dimethoete Dimethyl phoephorochlondothioate Dimetilan Dirutrocresoi Dtnoeeb Dinoterb Dioxatbion Diphacinone Diphosphoramide, octamethytDisulfoton 1.3-Duhiotane-2-carboicaldehyde, 2,4-cltmethyl-. 0-(methylcarbamoyi)oxime EPN Endosulfan Endothjon Endrin Ethion Ethopropbos FenamiphM Fenitmthion Fensulfocbion Fluenetll Fluomacetamide Fluotuecstic add Fonotos Formecanate Formochion Formparanate Fosthiecan Fubendaxole Hexachlorocydopentadiena Isobenraa isodrin Isopropylmethylpyramiyl dimethylcarhamate Leptopfaos Lindane Mephoefolan Methamidophos Methidithloa Methiocarb Metbomyi Methyl bromide Methyl phenkapcoo Metolcarb Mevuipfaoe Mexecarbate Monocnxopboa Nicotine Nicotine sulfate Norbonnide Oxamyt Oxydisulfoton Paraquat Paraquat matboeuifata Parathion Parsthwn-tnethyl Pari* green Penuchloropbenol Perchloromathylmcrcaptan Phenarsazine oxide Phenol. 24'-thiobis(4-ehlon>--methyl)- Phenol. 2,2'-thio6is(4,S-dichloro>- Phenoi. 3-(l-meihylethyl)-. methylcar- bamate Phorata Phosacatim Phoafolan Phosmet Phosphamidoo Phoepbonothioic add, methyl-. 0-(4- nitrophenyDO-phenyl ester Phoepbonothioic add. methyl-. O-ethyl 0-[4-(methylthio)phenyl] ester Phoepbonothioic acid, methyl-. S-(2-(di- isopropylamiDO)ethyl) O-ethyl ester Phosphoric acid. dimethyl 4-(methy(c/uo)pheny( ester Piprotal Pirimifos-ethyl Potassium arsenite Promecarb Prothoate Pyriminll Sodium arsenate Sodium arsenite Sodium cacodylate Sodium fluomaceute Sodium pentachlorophenate Strychnine Strychnine sulfate Sulfotep TEPP Terbufoe Tetraethyl tin Thiocyanic acid. (2-benzothiazoMthio)- methyl ester Thiofanox Thiometon Thionazin Thiourea. (2-chlorophenyl)- Thiourea. (2-methylphenyl)- Tnamiphos Triazofos Trichloronate Tnchlorphon T nmethyl tin chloride Triphenyl tin chloride Warfarin Warfarin sodium Zinc phosphide Zinc. dichlorof 4,4-dimethyl- 5. ([ [ (methylamtno)carbonyI ]oxy 1 imino | pentanetutrile]-.(T-4)- Plasticizing Compounds -- 26 Some overlap with cyanides. These are small molecules, much more dan gerous than finished product, that are chained together to form stable plas tics and synthetic rubbers. Acrylamide Butadiene Dibutyi phchalace Dimethyl phthalate Dloctyt phthalate Dimethyldichloroailane Dithiobiuret Isophorone di-isocyanate Methacryloyloxveihyi isocyanate Methyl 2-chloroacrylate Methyl vinyl ketone Methyltnchlorosilane Oxetane. J.3-bis(ch!oromethyl) Propylene glycol, ally! ether Pyridine. 2-methyl-S.vinyl Silane. (4-anunobutyl)diethoxymethylToluena. 2.4-di-isocyanate Toluene. 2.S-di-isocyanate TnchlorofcfiioromethyI)silane Tnchloro(dichlorophenyl)silane Trichloroethytsilane Trichiorophmylsilane Triethoxysilane Trtmetnylchlarosilane Vinylnerbomenr Vinvl ir**r ,rp mo^orn-r Metals and Compounds--7% Wide variety of uses, from photo- chemicals to pesticides to gasoline additives. Typically they interfere with human enzymes, inhibiting the metabolism of food and other sub stances. Cadmium oxide Cadmium stearate Chromic chloride Cobalt Cobalt carbonyl Ethylmercuric phosphate Gallium trichloride Iridium tetrachloride Iron pentacarbonyl Mercuric acetate Mercuric chloride Mercuric oxide Methoxyethylmereunc acetate Methvlmercunc dicvanamide Nickel Nickel carbonyl Osmium te'roxide Phenylmercurv acetate Plntinous . tilonde Platinum tetrachloride Rhodium trichloride Tellurium Tetraethyl lead Tetramethyl lead Thallic oxide Thallous carbonate Thallous chloride Thallous malonate Thallous sulfate Solvents--6 Widely used in paints and cleaning materials. They cause damage to the liver, nervous system and other sys tems. Cyclopentane Carbon disulfide Chloroform Cumene Isopropanol Methanol (methyl al. Ml) S PI-05513 THE NEW YORK TIMES Wednesday, November 20, 1985 (Cont'd.) Chemical Warfare Agents -- 7 Often chemically related to pesti cides. they are designed to harm humans. Some cause violent respira tory system blistering, Others cause nerve damage. Most have been made for the Defense Department and stored at classified sites. EttiylbU(2-chloroethyl)amine (nitrogen mustard gas) Isofluorphate Lewisite Mustard gas Sarin Tibun Tetranitrometnane < - t gis) Flavors and Fragrances --3 Used in mnuf.ic'ur? ind process ing. Like medicines, oeneficial in small doses, harmrul in large doses. Butyl isovalerate Curvone (peppermint, caraway) Orotic acid Catalysts and Reagents--12 Used to assist and measure chemi cal reactions. Ammonium chloroplatinate Antimony pentafluonde Beiuenearsonic acid Boron trichloride Boron tnfluor.de Boron tnfluonde compound witn methyl rther Lithium hydrd* r'.r.n.efClt uc d ov-Mine. t-amino' <lium azide ruamum letracmoride Vanadium pentou.d- Miscellaneous -- It Chemicals for which no use is known; those used largely in re search; those with odd uses. Cobalt (II). N.N'-ethylenebis(3-(luoro salicylideneiminato)- Decaborane(M) Dimethylhydraane Hexachioronaphthalene Isopropyl formate Manganese, tricarbonyl methylcyclopentadienyl Nitrosodiraethylamine Organorhodium complex Pentaborane Pentachloroethane Phenyl dichloroanine Phenylsilatrane Pyrene Pyridine. 4-nitro-. i-oxide Salcomine Sodium anthraquinone-1-sulfonate Sulfoxide. J-chioropropyi octyl Tiimethylolpropane phoephite Xylylene dichloride jE.P.A. Program on Toxic Chemicals Is Criticized By STUART DIAMOND Jersey, criticized those voluntary have uniform standards, as there are The environmental Protection Agen aspects. "This program hopes for the with nuclear power plants. The Chemi cy's program for safer handling of dan good will of the people running the cal Manufacturers Association, an in Sgerous chemicals came under fire yes lants and that people in the towns will dustry group, has a program to encour terday from some legislators who at ive enough expertise .to understand age companies to cooperate with local tacked its voluntary nature and from the chemicals,'' said Mr. Florio, chaircommunities in emergency planning. some companies that said they sold quantities too small for concern. The program includes the Identifica man of the House Energy and Com merce Subcommittee on Commerce, Transportation and Tourism, which Some of the companies that handle the most toxic chemicals are small concerns that sell sample quantities to tion of 103 toxic chemicals that could oversees the enforcement of various laboratories and universities. Chemi cause injury or death from chemical major environmental laws. cal experts said that the total inventory plant accidents. At least 977 companies Differing Standards Feared of the many small individual quantities handle those chemicals at thousands of In an interview, he said that even if could be significant in an explosion or locations, according to an analysis of such programs worked, they would re fire. But some of the companies said the list by The New York limes. The sult in different safety standards in dif they should not be lumped with the agency relies on municipalities to find ferent communities. "There will be no giant concerns that often store millions the plants handling the chemicals and uniformity," he said. of pounds of toxic chemicals. on chemical plants to disclose the infor E.P.A. officials and chemical indus "We are more like a drugstore than a mation and make any changes to re try executives have said that the chem giant chemical plant," said Arthur J. duce excessive risks. ical industry is so large and diverse Turco, president of the Crescent Chem James J. Florio, Democrat of New that it is difficult, if not impossible, to ical Company in Hauppauge. L.I. SPI-05514