Document xjddY2p7qrOwa6j5dD7p2Mad6

AR226-2764 FOR DP PONT OSE ONLY H askell LabEEol.rkatZtoo.nrdyRufooPadre,nTtNodxeewicaNorlkeo,mgoDyueraslnawdenadIrneCdou1ms9pt7ar1ni1ayl Medicine HASKELL LABORATORY REPORT NO. 295-81 aOmemtaonniouMimcaasteacrliidta*,l Tpeenstteaddecafluoro-, H a1ak', e03ll7N oT S tu d y5 /2I n0l/t8l0a t e-d /6C/1o7m/8p0l e t e d b HCHaAaDk eDl lepLaartbmoerna tt o r y JPTb..hyroeFfgcienLheimnDedtnrd5uaae0lrgyeaevn.;a*yads*oltuuoTrenlbhcgeswearitavnedsetauudctlbatmdalcCutuairrotillnteanCgrteDiiadna*Ol,Rfr1sAraai4Lons-tmdgst|ijDa,aleyt5h10seu0rdeTsomcpEpsoSeeeoTsvrnrestgItiraNooyrlon-i6RutpyApiengT.rdiSroocaduTotaphrnaesundssooiufintrlghmv, eiavnwtlhieanesagaamnacrddreaitmhf6tisoicndgewirsdooetu.ferperDesd. Resultat M(mDaogles/kesg) 1,000 670 AWveeriagghet (Bgo)d" 264 252 Sus(pXe)nsion 10 10 DAosveeraCgmeL) 2.64 1.69 M Ro rattai loi t y 10/10 9/10 LD50*** 470 mg/kg 500 253 10 1.27 6/10 450 241 10 1.09 4/10 400 257 5 2.05 3/10 200 247 1 4.93 2/10 - 1Company Sanitized. Does not contain TSCA CBI Result: F(aDegoa/sakelge)s AWveerlasghet B(go)dy Sus(pXe)nsion DAosveera(agLe) MRorattailoity LD50*** 1,000 189 10 1.89 10/10 482 ag/kg 670 182 10 1.22 9/10 500 195 450 212 5 1.95 7/10 5 1.91 5/10 a 400 197 5 1.57 0/10 C l2i0n0ica l Siena2:28 1 4.56 0/10 Mleavleels: teSsttaeidn*ed and/or net perineal area, weakness and weight lo ss a t a l l Chroaodacryorrhea a t 1,000 and S00 ag/kg. Stained face a t 1,000, 670, 500 and 650 ag/kg. Morlbundlty, eyes half-closed and gasping at 670 ag/kg. Hiaiped posture a t 500 ag/kg. All deaths occurred within A days a fter dosing. Feaalea: Stained and wet perineal area and weight loss at a ll lev els tested . Stained face a t a l l levels tested accept 200 ag/kg. Veakness a t 1,000, 670, 450, and 400 ag/kg. Chroaodacryorrhea, eyes half-closed and ataxia at 670 ag/kg. Heaped posture a t 670 and 450 ag/kg. Alopecia a t 400 ag/kg. All deaths occurred within 3 days after dosing. - 2- dcfmoSehourgmrsma/oikalnmmgllgyeaor.saydnt:aoIdcnrcAyfyelomoumumrdnraeohglndeei:usaam,dluaasplnttead4ri8Cfn2lreulesdomiCgrDgoha/noktdgeltoawoanslfeesot.bapaotnedeAdyrillnawfleeemdamielgaoalhadetthre.serraaatoC,teecllsc;yitunaIrtiiroctnesxaedlidcLwDsfiw5igat0hhnceeisfnno, afr4wodmrmedaamalklnyenalseaelestasIessf,retaedn4rd70 Synonyms U o C-8 ^ perfluorooetanoate 1J i Purity; 1 Contaminants: 0 L CAS R eg istry Ho.: ^ l PFfi6n8n8ey , D. J . , P roblt A n.alysis. 3rd Ed., 1971, Cambridge U niversity 9SZ Confidence L ia ltg : DSHLjojLapwolpepeeserr::: SUFLilopeowpmpeeearrl:::es 84530.663 mmgg//kkgg 15443218.3 mmgg//kkgg t - 3 - ,,BizeiDM 5notcontain TSCA Reviewed by: $ 0S. tuLdoyuiDe iDreacetholrell Ap;:proved by: Chief* A cGuteer aIlnd vLe .s tKi geantnieodnys * Section ^.DJAeHte:jrIsgsuedj_ JuneJL, 1981 Report No. 295-81 ^ i - 4- not contain TSCACDl CemPaKi Sanfflied.Does