Document xj2vyoxqga9ZYRDYDMknMKEg6

(`>'7 --1'u.uoaK ; PLAINTIFF'S EXHIBIT jOGcr>:-i l. good;:/.:!, r.*. d. 623 O'HEAn .V/ZZl'JS NORTH CHAnUCiTCU. Z. 23*!C0 November 10, 1972 - PLAINTIFF'S [ EXHIBIT' \ ->7 s -J - f Mr. William S. Simpson, President R.aybcstos-Manhattan, Inc. 205 Middle Street Bridgeport,- Connecticut 06603 ' . Dear Mr, Simpson: This is a review of the meeting in Lyon, France, the subject of which was the Biglqnical Effects of Asbestos.' The real purpose and impor tance of tins meeting seems to indicr.ta :c me that there is a distinct trend ia the thought of people internationally associated with the bio logical effects of asbestos in its relationship to disease, mainly asbes tos i^Si^^^^t^^^rcater extent its significant effect on the individual in The translation of this knowledge into future efforts by Raybestos-Manhattan Corporation and its medical pcrsar.ncl in relationship to the scientists, the public, and to the government remains to be evaluated. I think it would be appropriate to discuss the future trends and the course of action that was being taken by all parties concerned in this discuroion. At there is no doubt - ro question - that the biological cffcct3ft&rti;g,k8ftoa -leads to asbestosis Kr.i to carcinoma ot the lung; both baoafiAogmcsarcinoma and me sotheliomn-. .As far as the different aspects of the cficct of different types of asbestos arc concerned, ail typMWlMffiS3SS<&ra-ancriminatedr' -8*PWTerc paper? presented which oilonta ia causecLV/-fiffflSblitc, a'mosite, and chry so tileesdShcse particular car.ccrs of the iur.;- arc of extreme importance and lately have been given nationai and in"crelational publicity. Consideration is being given to the i:v a: relative to the possibility that other typ. a relationship to asbestos exposure. Vi hut there was shown a: this particular r. this direction relative to g astro-into srir of rare tumors, such as the pancreas, clintx* p.,rs ol the ir,teiu-vl tri*cl. in. I..rn previously ruco^tiit; >. l i.c :xri>-. . lji.s rlieii.iT' type k*i iVivi.'Oi'iiVnmtul a.. bee t uwe no.v cm: ihe j T;;jl;'*..V.xor,,: -tt orgaiiH of the body, hi though u is tru-a major primary organ o' die i -<*/ which corn, iiui'i it-1 r, unnr vn, .-nl ihr *_. ,1,1*1 r | l in 111, * , 11 , ,*, n;vi n, ,ii-v"*(- ;, j*'l|i'i',i I in* lu;-l r y .iii.i i * th * ., g( - me Ml iin- the i11\ji>ifltvr>cc of uvicli rc-loiirms in liio : 'gatiens that wc arc pursuing of tumors of the body may have ; r.i the present time is r.ac firm, :::ng that there is a trer.d ic.v.ini tumors and possibly other *ypes ;-pJ ngu.'i, p-ivts of llic colon, and u ,, point of view which ii'is .lot and mi.-dichi iutpiicaiion.; of .,ure is a:.tr..meiy important dikional ;ai:!. 1 i -- i*y aflectir.;; -w* in*.: rerpirmory sys;*.m i.-. a Reeled. Tho coni|*.' ny'.; *:on- i:ki1 iv C.*un:i; i*u, ;ir. **ir* *vr * r i*i * * * <*! * \-i* *1 l*v ill** i *'' *' 1 i * ,1.1(1 li nn uni ml *! y i ei i,;ni.'.i' nr. a. I II or to the tT^ce elements, but that there ire indications that the fiber si7.e anti shape are important and that mesotheliomas have been produced with fiberglass and other non-as'oestos materials. In intrapleural experiments ,usa&Aayg prodagatt nivWirtiitclionn.'is in rats. A per centage ugura which you might use as a measure is 61% of animals pro duced cancer with crocidolite, 36% with t-mosite, 3-1% with antophyllite, 30% with Canadian chrysotilc, and 19% with Rhodesian chrysocilc. A great many of the people felt that the trace metals were extremely rele vant. The greatest conclusion of all was that in employment in asbestos, especially the insulation worker, smoking his a greater affect on arbes- tosis and lung cancer than anything else, and every one of the asbestos workers should stop smoking. .. / \ There was great criticism of Dr. Selikofi's paper by Dr. J. C. McDonald. He felt that the statistics presented in this paper were not accurate. He talked about the inebriation workers and be asked why the insulation workers that were not included in the union were not presented as a part of the study. 1 could go on for hours with various types of difficulties and prob lems they had with asbestos, but one of the main things I would like to * convey to you is that glass fiber is carcinogenic. With a peritoneal irri tation and the addition of bensopyrine with chrysotile a high rate of inci dences of carcinoma was produced. Chrysotile alone produced a very low Incidence of mesothelioma. . In summary, I would say that there are many salient features to the dis- eusoions that were held at Lyon: (1) TLlBB>fi6fcbsolutcly a direct eonr.ee tMfi^SBBMWmpNUU'<a.asbcstos and mepprfcjjftiioma, broncogcnic earci- nocay^tt^4--afesaBSHiL--a8bestosia. {Z) The union representative was adamant in that there will be a revolution in their particular area bring ing about the necessity of industry getting ahead of the problem by intro ducing an educational program that will orient the worker as to what he is exposed to. Of course, this must be done'by medically oriented per- conncl so that an aura of hysteria is not created. Thu facts arc to be presented in a logical sequence in a manner of importance to such an extent that there-will be a complete compliance with die OSKA require ments, and yet, not cause fear among employees. It must show tin- company's interest in the employees' health and what the company is doing to protect and safeguard their exposure. (3) There will be in-' creasing publications and press releasee related io the significant "epidemic" of mesothelioma r.nd other types of carcinoma of the G. 1, tract, pancreas, etc., ; and then, anticipation of this particular rela tionship should be combatted by educational orientation of the employee, it should be emphasised that the people vhc am most a: risk are liic workers and they should be taught ia use mstuvlais safely an.i with con cern. (4) There should be a complete medical program. A complete survey of all the systems including the pulmonary system by u.-u of modern environmental and nic-du-i tr.c-a..i; available to u.s and that-a / ro/jtllar VOUlinri education |u.j,m.u.,i Li o..ordin.u; ! v/ith ii,i-> ev.Mi.i 'Mioi1. A film strip or ;t film should be prepared for the orien tation "f liu: t-it p'l-iyco, especially since C.hliiA vi put.-aion-i allow the individual to .*.:! for bin exposure, iito a;..;iunt of cxpu.-.ure, and the dust to wlu*'ii ho hnn boon oKpmtrd, 1 think f>. t ti,ir. pm:; i-:i m will In-in:'. ab-nii. jyi-.iU'i- j nil-1 i>- i-i-lii l i*iiii< liy i.'li.ii til i*i-'*,i,-, Iwtti 11 iii-iIIci- wiud ,1111.111 lii,nn a public reunions man will prod. A public education pro*:r; m is certainly in order in which one can, 1 believe, through the utouia of television, radio, and news pa pur edruato liie pulnir. as to the im::ovi.incc of asbestos, its uses, the budopical offsets of asi.usios, its coin. Cm ", u1 tii) wii r t and Its Indispensability to our modern technological society. It should be stressed that if properly used i-nci properly controlled, it is a perfectly safe product. I want to thank you very much for the opi ortunity to come in con- . tact with some of the world's greatest scientists and international experimenters. I had the opportunity of .sittisig next to the inves tigator from Moscow who invited me to Moscow to visit his labora tory. I also had the opportunity of having long conversations and discussions with Dr. Gilson, Dr. Wagner, Dr. V.'cbstcr, Dr. Cctin and many others with International importance and found myself readily acceptable at their level. Of course, there is a great deal more to be discussed about this subject, but I certainly donlt think this is (he place for it. There are volumes and volumes oi infor mation ar.d letters that 1 have read and have with me, and perhaps, at an opportunity that presents itself v/c will be able to discuss it person to person. . 1 send my boot personal regards to you. . JLG/shl i.