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Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 5 Book Section MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary Zotero Zotero Zotero Zotero 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Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary 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Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 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Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary 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Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal 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Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 5 Book Section 5 Book Section 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary MyLibrary Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero Zotero 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article 17 Journal Article author European Chemicals Agency European Chemicals Agency European Chemicals Agency European Chemicals Agency European Chemicals Agency European Chemicals Agency European Chemicals Agency De Silva, A. O. Armitage, J. M. Bruton, T. A. Dassuncao, C. Heiger-Bernays, W. Hu, X. C. Krrman, A. Kelly, B. Ng, C. Robuck, A. Sun, M. Webster, T. F. Sunderland, E. M. De Silva, A.O. Armitage, J.M. Bruton, T.A. Dassuncao, C. Heiger-Bernays, W. Hu, X.C. Krrman, A. Kelly, B. Ng, C. Robuck, A. Sun, M. Webster, T.F. Sunderland, E.M. De Silva, A. O. Tseng, P. J. Mabury, S. A. Kudo, Naomi Kudo, Naomi Kawashima, Yoichi Ahrens, L. Siebert, U. Ebinghaus, R. Chen, M. Zhu, L. Wang, Q. author4 DeWitt, Jamie C. DeWitt, Jamie C. Shan, G. Martin, J.W. Mabury, S.A. Solomon, K.R. Muir, D.C.G. Shi, Y. Song, X. Jin, Q. Li, W. He, S. Cai, Y. Shi, Yali Vestergren, Robin Nost, Therese Haugdahl Zhou, Zhen Cai, Yaqi Armitage, J.M. Arnot, J.A. Wania, F. Luebker, D.J. Hansen, K.J. Bass, N.M. Butenhoff, J.L. Seacat, A.M. Ng, C. A. Hungerbhler, K. Ebert, A. Allendorf, F. Berger, U. Goss, K.-U. Ulrich, N. Pizzurro, D.M. Seeley, M. Kerper, L.E. Beck, B.D. Zhao, W. Zitzow, J.D. Weaver, Y. Ehresman, D.J. Chang, S.-C. Butenhoff, J.L. Hagenbuch, B. Consoer, D.M. Hoffman, A.D. Fitzsimmons, P.N. Kosian, P.A. Nichols, J.W. Borg, D. Hkansson, H. Harada, Kouji H. Hashida, Shuhei Kaneko, Takaaki Takenaka, Katsunobu Minata, Mutsuko Inoue, Kayoko Saito, Norimitsu Koizumi, Akio Leranth, Csaba Szigeti-Buck, Klara MacLusky, Neil J. Hajszan, Tibor Verreault, J. Houde, M. Gabrielsen, G. W. Berger, U. Haukas, M. Letcher, R. J. Muir, D. C. Gckener, B. Eichhorn, M. Lammer, R. Kotthoff, M. Kowalczyk, J. Numata, J. Schafft, H. Lahrssen-Wiederholt, M. Bucking, M. Jouanneau, William Landri-Breton, Don-Jean Corbeau, Alexandre Herzke, Dorte Moe, Brge Nikiforov, Vladimir A. Gabrielsen, Geir W. Chastel, Olivier Kowalczyk, J. Gckener, B. Eichhorn, M. Kotthoff, M. Bcking, M. Schafft, H. Lahrssen-Wiederholt, M. Numata, J. Henderson, W. M. Smith, M. A. Han, X. Snow, T.A. Kemper, R.A. Jepson, G.W. Ng, C. A. Hungerbhler, K. Zhang, L. Ren, X.-M. Guo, L.-H. Allendorf, F. Berger, U. Goss, K.-U. Ulrich, N. Armitage, J.M. Arnot, J.A. Wania, F. Bischel, H.N. Macmanus-Spencer, L.A. Zhang, C. Luthy, R.G. Droge, S.T.J. Sheng, N. Li, J. Liu, H. Zhang, A. Dai, J. Weaver, Y.M. Ehresman, D.J. Butenhoff, J.L. Hagenbuch, B. Woodcroft, M.W. Ellis, D.A. Rafferty, S.P. Burns, D.C. March, R.E. Stock, N.L. Trumpour, K.S. Yee, J. Munrok, K. Martin, J. W. Mabury, S. A. Solomon, K. R. Muir, D. C. Martin, J. W. Mabury, S. A. Solomon, K. R. Muir, D. C. G. Allendorf, Flora Goss, Kai-Uwe Ulrich, Nadin Allendorf, F. Berger, U. Goss, K.-U. Ulrich, N. Gao, Ke Zhuang, Taifeng Liu, Xian Fu, Jianjie Zhang, Jingxing Fu, Jie Wang, Liguo Zhang, Aiqian Liang, Yong Song, Maoyong Jiang, Guibin Zhang, T. Sun, H. Lin, Y. Qin, X. Zhang, Y. Geng, X. Kannan, K. Death, C. Bell, C. Champness, D. Milne, C. Reichman, S. Hagen, T. Sharpe, Rainie L. Benskin, Jonathan P. Laarman, Anne H. MacLeod, Sherri L. Martin, Jonathan W. Wong, Charles S. Goss, Greg G. Grnnestad, R. Villanger, G.D. Polder, A. Kovacs, K.M. Lydersen, C. Jenssen, B.M. Borg, K. Prez, Francisca Nadal, Mart Navarro-Ortega, Alcia Fbrega, Francesc Domingo, Jos L. Barcel, Dami Farr, Marinella Ng, C.A. Hungerbhler, K. Ahrens, L. Bundschuh, M. Hassell, K.L. Coggan, T.L. Cresswell, T. Kolobaric, A. Berry, K. Crosbie, N.D. Blackbeard, J. Pettigrove, V.J. Clarke, B.O. Arnot, J. A. Gobas, F. A. Chen, F. Gong, Z. Kelly, B.C. Kelly, B. C. Gobas, F. A. McLachlan, M. S. Henneberger, L. Goss, K.-U. Endo, S. Chen, F. Gong, Z. Kelly, B.C. deBruyn, A. M. H. Gobas, F. A. P. C. Gobas, Frank A.P.C. Mayer, Philipp Parkerton, Thomas F. Burgess, Robert M. van de Meent, Dik Gouin, Todd Gobas, Frank A.P.C. Otton, S.Victoria Tupper-Ring, Laura F. Crawford, Meara A. Clark, Kathryn E. Ikonomou, Michael G. Gobas, F Wang, Z. MacLeod, M. Cousins, I. T. Scheringer, M. Hungerbhler, K. Armitage, J.M. Erickson, R.J. Luckenbach, T. Ng, C.A. Prosser, R.S. Arnot, J.A. Schirmer, K. Nichols, J.W. Armitage, James M. Arnot, Jon A. Wania, Frank Mackay, Don Ng, C. A. Hungerbuhler, K. Ankley, G.T. Cureton, P. Hoke, R.A. Houde, M. Kumar, A. Kurias, J. Lanno, R. McCarthy, C. Newsted, J. Salice, C.J. Sample, B.E. Seplveda, M.S. Steevens, J. Valsecchi, S. Andersen, M. E. Butenhoff, J. L. Chang, S. C. Farrar, D. G. Kennedy, G. L. Lau, C. Olsen, G. W. Seed, J. Wallace, K. B. Khazaee, M. Ng, C.A. Kwadijk, C. J. A. F. Korytar, P. Koelmans, A. A. Labadie, P. Chevreuil, M. Munoz, G. Budzinski, H. Babut, M. Drouineau, H. Lauzent, M. Menach, K.L. Lobry, J. Selleslagh, J. Simonnet-Laprade, C. Labadie, P. Chen, M. Wang, Q. Shan, G. Zhu, L. Yang, L. Liu, M. Arnot, Jon A Gobas, Frank APC Chen, F. Gong, Z. Kelly, B.C. Dai, Z. Xia, X. Guo, J. Jiang, X. Hoke, Robert A. Ferrell, Barbra D. Ryan, Tim Sloman, Terry L. Green, John W. Nabb, Diane L. Mingoia, Robert Buck, Robert C. Korzeniowski, Stephen H. Inoue, Y. Hashizume, N. Yakata, N. Murakami, H. Suzuki, Y. Kikushima, E. Otsuka, M. Abercrombie, S.A. de Perre, C. Choi, Y.J. Tornabene, B.J. Seplveda, M.S. Lee, L.S. Hoverman, J.T. Ng, C.A. Hungerbhler, K. de Wit, Cynthia A. Bossi, Rossana Dietz, Rune Dreyer, Annekatrin Faxneld, Suzanne Garbus, Svend Erik Hellstrm, Peter Koschorreck, Jan Lohmann, Nina Roos, Anna Sellstrm, Ulla Sonne, Christian Treu, Gabriele Vorkamp, Katrin Yuan, Bo Eulaers, Igor Fair, Patricia A. Wolf, Beth White, Natasha D. Arnott, Stephen A. Kannan, Kurunthachalam Karthikraj, Rajendiran Vena, John E. Guillette, T. C. McCord, James Guillette, Matthew Polera, M. E. Rachels, Kyle T. Morgeson, Clint Kotlarz, Nadine Knappe, Detlef R. U. Reading, Benjamin J. Strynar, Mark Belcher, Scott M. Eggers Pedersen, K. Basu, N. Letcher, R. Greaves, A.K. Sonne, C. Dietz, R. Styrishave, B. Wood, C. Balazs, G.H. Rice, M. Work, T.M. Jones, T.T. Sterling, E. Summers, T.M. Brooker, J. Kurpita, L. King, C.S. Lynch, J.M. Giesy, J.P. Kannan, K. Ahrens, L. Bundschuh, M. Penland, T. N. Cope, W. G. Kwak, T. J. Strynar, M. J. Grieshaber, C. A. Heise, R. J. Sessions, F. W. Houde, M. De Silva, A. O. Muir, D. C. Letcher, R. J. Muir, Derek Bossi, Rossana Carlsson, Pernilla Evans, Marlene De Silva, Amila Halsall, Crispin Rauert, Cassandra Herzke, Dorte Hung, Hayley Letcher, Robert Rigt, Frank Roos, Anna Reiner, J. L. O'Connell, S. G. Moors, A. J. Kucklick, J. R. Becker, P. R. Keller, J. M. Lanza, H.A. Cochran, R.S. Mudge, J.F. Olson, A.D. Blackwell, B.R. Maul, J.D. Salice, C.J. Anderson, T.A. Groffen, T. Rijnders, J. Verbrigghe, N. Verbruggen, E. Prinsen, E. Eens, M. Bervoets, L. Liu, Z. Lu, Y. Wang, P. Wang, T. Liu, S. Johnson, A.C. Sweetman, A.J. Baninla, Y. Lopez-Antia, A. Kavelaars, M. M. Mller, W. Bervoets, L. Eens, M. Larson, E.S. Conder, J.M. Arblaster, J.A. Fang, S. Chen, X. Zhao, S. Zhang, Y. Jiang, W. Yang, L. Zhu, L. Loi, E.I.H. Yeung, L.W.Y. Taniyasu, S. Lam, P.K.S. Kannan, K. Yamashita, N. Martin, J. W. Whittle, D. M. Muir, D. C. Mabury, S. A. Kelly, B. C. Ikonomou, M. G. Blair, J. D. Surridge, B. Hoover, D. Grace, R. Houde, M. Czub, G. Small, J.M. Backus, S. Wang, X. Alaee, M. Muir, D.C.G. Chen, Y. Fu, J. Ye, T. Li, X. Gao, K. Xue, Q. Lv, J. Zhang, A. Fu, J. Zhang, X. Lohmann, R. Sunderland, E. M. Spaan, Kyra M. van Noordenburg, Carmen Plassmann, Merle M. Schultes, Lara Shaw, Susan Berger, Michelle Heide-Jrgensen, Mads Peter Rosing-Asvid, Aqqalu Granquist, Sandra M. Dietz, Rune Sonne, Christian Rigt, Frank Roos, Anna Benskin, Jonathan P. Chengelis, Christopher P. Kirkpatrick, Jeannie B. Myers, Nichole R. Shinohara, Motoki Stetson, Philip L. Sved, Daniel W. Gannon, Shawn A. Johnson, Terry Nabb, Diane L. Serex, Tessa L. Buck, Robert C. Loveless, Scott E. Numata, Jorge Kowalczyk, Janine Adolphs, Julian Ehlers, Susan Schafft, Helmut Fuerst, Peter Mller-Graf, Christine Lahrssen-Wiederholt, Monika Greiner, Matthias Russell, M. H. Nilsson, H. Buck, R. C. Furdui, V. I. Stock, N. L. Ellis, D. A. Butt, C. M. Whittle, D. M. Crozier, P. W. Reiner, E. J. Muir, D. C. Mabury, S. A. Wang, Y. Vestergren, R. Shi, Y. Cao, D. Xu, L. Cai, Y. Zhao, X. Wu, F. Bogdanska, Jasna Borg, Daniel Bergstrm, Ulrika Mellring, Maria Bergman, ke DePierre, Joseph Nobel, Stefan Danish Environmental Protection Agency Wen, W. Xia, X. Hu, D. Zhou, D. Wang, H. Zhai, Y. Lin, H. Jin, Qi Shi, Yali Cai, Yaqi Hoke, R. A. Ferrell, B. D. Sloman, T. L. Buck, R. C. Buxton, L. W. Shi, Y. Vestergren, R. Zhou, Z. Song, X. Xu, L. Liang, Y. Cai, Y. Li, Y. Yao, J. Zhang, J. Pan, Y. Dai, J. Ji, C. Tang, J. Lee, H. De Silva, A. O. Mabury, S. A. Crookes, M J Fisk, M Campo, J. Lorenzo, M. Prez, F. Pic, Y. Farr, M. Barcel, D. Blum, Arlene Balan, Simona A. Scheringer, Martin Trier, Xenia Goldenman, Gretta Cousins, Ian T. Diamond, Miriam Fletcher, Tony Higgins, Christopher Lindeman, Avery E. Conder, Jason M. Hoke, Robert A. Wolf, de Watze Russell, Mark H. Buck, Robert C. title Background document to the Opinion on the Annex XV dossier proposing restrictions on C9-C14 PFCAs including their salts Member State Committee Support Document for Identification of Perfluorohexane-1-sulphonic acid and its salts as Substa Background document to the Opinion on the Annex XV dossier proposing restrictions on Perfluorooctanoic acid (PFOA), PF Agreement of the Member State Committee on the identification of Pentadecafluorooctanoin acid (PFOA) as a substance o Member State Committee support document for identification of pentadecafluorooctanoic acid (PFOA) as a substance of v Member State Committee support document for identification of heptacosafluorotetradecanoic acid as a substance of ver Inclusion of substances of very high concern in the Candidate List PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i PFAS Exposure Pathways for Humans and Wildlife: A Synthesis of Current Knowledge and Key Gaps i Toxicokinetics of perfluorocarboxylate isomers in rainbow trout Toxicokinetics of perfluorocarboxylate isomers in rainbow trout Toxicokinetics of perfluorocarboxylate isomers in rainbow trout Metabolism and Pharmacokinetics Metabolism and Pharmacokinetics Metabolism and Pharmacokinetics Toxicity and Toxicokinetics of Perfluorooctanoic Acid in Humans and Animals Toxicity and Toxicokinetics of Perfluorooctanoic Acid in Humans and Animals Total body burden and tissue distribution of polyfluorinated compounds in harbor seals (Phoca vitul Total body burden and tissue distribution of polyfluorinated compounds in harbor seals (Phoca vitul Total body burden and tissue distribution of polyfluorinated compounds in harbor seals (Phoca vitul Tissue distribution and bioaccumulation of legacy and emerging per-and polyfluoroalkyl substances (P Tissue distribution and bioaccumulation of legacy and emerging per-and polyfluoroalkyl substances (P Tissue distribution and bioaccumulation of legacy and emerging per-and polyfluoroalkyl substances (P Tissue distribution and bioaccumulation of legacy and emerging per-and polyfluoroalkyl substances (P Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Tissue distribution and bioaccumulation of a novel polyfluoroalkyl benzenesulfonate in crucian carp Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalky Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalky Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalky Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalky Probing the Differential Tissue Distribution and Bioaccumulation Behavior of Per- and Polyfluoroalky Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Interactions of flurochemicals with rat liver fatty acid-binding protein Interactions of flurochemicals with rat liver fatty acid-binding protein Interactions of flurochemicals with rat liver fatty acid-binding protein Interactions of flurochemicals with rat liver fatty acid-binding protein Interactions of flurochemicals with rat liver fatty acid-binding protein Bioconcentration of perfluorinated alkyl acids: how important is specific binding? Bioconcentration of perfluorinated alkyl acids: how important is specific binding? Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternative Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternative Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternative Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternative Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternative Interspecies differences in perfluoroalkyl substances (PFAS)toxicokinetics and application to health-ba Interspecies differences in perfluoroalkyl substances (PFAS)toxicokinetics and application to health-ba Interspecies differences in perfluoroalkyl substances (PFAS)toxicokinetics and application to health-ba Interspecies differences in perfluoroalkyl substances (PFAS)toxicokinetics and application to health-ba Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Organic anion transporting polypeptides contribute to the disposition of perfluoroalkyl acids in huma Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout (Oncorhynchus mykiss) Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout (Oncorhynchus mykiss) Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout (Oncorhynchus mykiss) Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout (Oncorhynchus mykiss) Toxicokinetics of perfluorooctanoate (PFOA) in rainbow trout (Oncorhynchus mykiss) Environmental and Health Risk Assessment of Perfluoroalkylated and Polyfluoroalkylated Substances Environmental and Health Risk Assessment of Perfluoroalkylated and Polyfluoroalkylated Substances Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Biliary excretion and cerebrospinal fluid partition of perfluorooctanoate and perfluorooctane sulfon Bisphenol A Prevents the Synaptogenic Response to Testosterone in the Brain of Adult Male Rats Bisphenol A Prevents the Synaptogenic Response to Testosterone in the Brain of Adult Male Rats Bisphenol A Prevents the Synaptogenic Response to Testosterone in the Brain of Adult Male Rats Bisphenol A Prevents the Synaptogenic Response to Testosterone in the Brain of Adult Male Rats Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Perfluorinated alkyl substances in plasma, liver, brain, and eggs of glaucous gulls (Larus hyperboreus Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: Transfer of Per- and Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 1: A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Transfer of Per- And Polyfluoroalkyl Substances (PFAS) from Feed into the Eggs of Laying Hens. Part 2: Perfluorooctanoic acid and perfluorononanoic acid in fetal and neonatal mice following in utero expo Perfluorooctanoic acid and perfluorononanoic acid in fetal and neonatal mice following in utero expo Binding of perfluorooctanoic acid to rat and human plasma proteins Binding of perfluorooctanoic acid to rat and human plasma proteins Binding of perfluorooctanoic acid to rat and human plasma proteins Binding of perfluorooctanoic acid to rat and human plasma proteins Exploring the Use of Molecular Docking to Identify Bioaccumulative Perfluorinated Alkyl Acids (PFAAs Exploring the Use of Molecular Docking to Identify Bioaccumulative Perfluorinated Alkyl Acids (PFAAs Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Potential role of phospholipids in determining the internal tissue distribution of perfluoroalkyl acids i Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of bin Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of bin Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of bin Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of bin Membrane-Water Partition Coefficients to Aid Risk Assessment of Perfluoroalkyl Anions and Alkyl Sul Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with differen Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with differen Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with differen Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with differen Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumul Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss) Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss) Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss) Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss) Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus myki Estimating the Equilibrium Distribution of Perfluoroalkyl Acids and 4 of Their Alternatives in Mammal Estimating the Equilibrium Distribution of Perfluoroalkyl Acids and 4 of Their Alternatives in Mammal Estimating the Equilibrium Distribution of Perfluoroalkyl Acids and 4 of Their Alternatives in Mammal Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Partition coefficients of four perfluoroalkyl acid alternatives between bovine serum albumin (BSA) and Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Prenatal Exposure to Per- and Polyfluoroalkyl Substances (PFASs) and Association between the Place Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Distribution of poly- and perfluoroalkyl substances in matched samples from pregnant women and ca Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Per- and polyfluoroalkyl substances (PFAS) in livestock and game species: A review Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Perfluorooctane sulfonate toxicity, isomer-specific accumulation, and maternal transfer in zebrafish Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Maternal transfer of perfluoroalkyl substances in hooded seals Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Accumulation of perfluoroalkyl substances in human tissues Bioaccumulation of perfluorinated alkyl acids: Observations and models Bioaccumulation of perfluorinated alkyl acids: Observations and models Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H Dietary Uptake and Depuration Kinetics of Perfluorooctane Sulfonate, Perfluorooctanoic Acid, and H A food web bioaccumulation model for organic chemicals in aquatic ecosystems A food web bioaccumulation model for organic chemicals in aquatic ecosystems Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Intestinal absorption and biomagnification of organic contaminants in fish, wildlife, and humans Intestinal absorption and biomagnification of organic contaminants in fish, wildlife, and humans Intestinal absorption and biomagnification of organic contaminants in fish, wildlife, and humans Partitioning of Organic Ions to Muscle Protein: Experimental Data, Modeling, and Implications for in V Partitioning of Organic Ions to Muscle Protein: Experimental Data, Modeling, and Implications for in V Partitioning of Organic Ions to Muscle Protein: Experimental Data, Modeling, and Implications for in V Bioaccumulation Behavior of Pharmaceuticals and Personal Care Products in Adult Zebrafish (Danio re Bioaccumulation Behavior of Pharmaceuticals and Personal Care Products in Adult Zebrafish (Danio re Bioaccumulation Behavior of Pharmaceuticals and Personal Care Products in Adult Zebrafish (Danio re The sorptive capacity of animal protein The sorptive capacity of animal protein A chemical activity approach to exposure and risk assessment of chemicals A chemical activity approach to exposure and risk assessment of chemicals A chemical activity approach to exposure and risk assessment of chemicals A chemical activity approach to exposure and risk assessment of chemicals A chemical activity approach to exposure and risk assessment of chemicals A chemical activity approach to exposure and risk assessment of chemicals Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i Chemical activity-based environmental risk analysis of the plasticizer di-ethylhexyl phthalate and i A framework for assessing bioaccumulation and exposure risks of per- and polyfluoroalkyl substances in threatened and en Using COSMOtherm to predict physicochemical properties of poly- and perfluorinated alkyl substanc Using COSMOtherm to predict physicochemical properties of poly- and perfluorinated alkyl substanc Using COSMOtherm to predict physicochemical properties of poly- and perfluorinated alkyl substanc Using COSMOtherm to predict physicochemical properties of poly- and perfluorinated alkyl substanc Using COSMOtherm to predict physicochemical properties of poly- and perfluorinated alkyl substanc Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and rese Development and evaluation of a mechanistic bioconcentration model for ionogenic organic chemicals Development and evaluation of a mechanistic bioconcentration model for ionogenic organic chemicals Development and evaluation of a mechanistic bioconcentration model for ionogenic organic chemicals Development and evaluation of a mechanistic bioconcentration model for ionogenic organic chemicals Bioaccumulation of perfluorinated alkyl acids: observations and models Bioaccumulation of perfluorinated alkyl acids: observations and models Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Assessing the Ecological Risks of Per- and Polyfluoroalkyl Substances: Current State-of-the Science Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Perfluoroalkyl acids and related chemistries--toxicokinetics and modes of action Evaluating parameter availability for physiologically based pharmacokinetic (PBPK) modeling of perfl Evaluating parameter availability for physiologically based pharmacokinetic (PBPK) modeling of perfl Distribution of Perfluorinated Compounds in Aquatic Systems in The Netherlands Distribution of Perfluorinated Compounds in Aquatic Systems in The Netherlands Distribution of Perfluorinated Compounds in Aquatic Systems in The Netherlands Partitioning behaviour of perfluorinated alkyl contaminants between water, sediment and fish in the Partitioning behaviour of perfluorinated alkyl contaminants between water, sediment and fish in the Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Evidence for the Trophic Transfer of Perfluoroalkylated Substances in a Temperate Macrotidal Estuar Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa Occurrence, partitioning and bioaccumulation of emerging and legacy per- and polyfluoroalkyl substa A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Bioavailability and bioconcentration potential of perfluoroalkyl-phosphinic and -phosphonic acids in Bioaccumulation and uptake routes of perfluoroalkyl acids in Daphnia magna Bioaccumulation and uptake routes of perfluoroalkyl acids in Daphnia magna Bioaccumulation and uptake routes of perfluoroalkyl acids in Daphnia magna Bioaccumulation and uptake routes of perfluoroalkyl acids in Daphnia magna Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Aquatic hazard, bioaccumulation and screening risk assessment for 6:2 fluorotelomer sulfonate Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Unique physicochemical properties of perfluorinated compounds and their bioconcentration in comm Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Larval amphibians rapidly bioaccumulate poly- and perfluoroalkyl substances Bioaccumulation of perfluorinated alkyl acids: Observations and models Bioaccumulation of perfluorinated alkyl acids: Observations and models Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Organohalogen compounds of emerging concern in Baltic Sea biota: Levels, biomagnification potenti Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Perfluoroalkyl substances (PFASs) in edible fish species from Charleston Harbor and tributaries, Sout Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxati Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Sea turtles across the North Pacific are exposed to perfluoroalkyl substances Global distribution of perfluorooctane sulfonate in wildlife Global distribution of perfluorooctane sulfonate in wildlife Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Trophodynamics of Per-and Polyfluoroalkyl Substances in the Food Web of a Large Atlantic Slope Riv Monitoring of perfluorinated compounds in aquatic biota: an updated review Monitoring of perfluorinated compounds in aquatic biota: an updated review Monitoring of perfluorinated compounds in aquatic biota: an updated review Monitoring of perfluorinated compounds in aquatic biota: an updated review Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Levels and trends of poly- and perfluoroalkyl substances in the Arctic environment - An update Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Spatial and temporal trends of perfluorinated compounds in Beluga Whales (Delphinapterus leucas) Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of hist Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Influence of soil physicochemical properties on the depth profiles of perfluoroalkylated acids (PFAAs) Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Pollution pathways and release estimation of perfluorooctane sulfonate (PFOS) and perfluorooctanoic Understanding PFAAs exposure in a generalist seabird species breeding in the vicinity of a fluorochemi Understanding PFAAs exposure in a generalist seabird species breeding in the vicinity of a fluorochemi Understanding PFAAs exposure in a generalist seabird species breeding in the vicinity of a fluorochemi Understanding PFAAs exposure in a generalist seabird species breeding in the vicinity of a fluorochemi Understanding PFAAs exposure in a generalist seabird species breeding in the vicinity of a fluorochemi Modeling avian exposures to perfluoroalkyl substances in aquatic habitats impacted by historical aq Modeling avian exposures to perfluoroalkyl substances in aquatic habitats impacted by historical aq Modeling avian exposures to perfluoroalkyl substances in aquatic habitats impacted by historical aq Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification and isomer fractionation of perfluoroalkyl substances in the food web of Taihu Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Trophic magnification of poly- and perfluorinated compounds in a subtropical food web Perfluoroalkyl contaminants in a food web from Lake Ontario Perfluoroalkyl contaminants in a food web from Lake Ontario Perfluoroalkyl contaminants in a food web from Lake Ontario Perfluoroalkyl contaminants in a food web from Lake Ontario Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Perfluoroalkyl contaminants in an arctic marine food web: trophic magnification and wildlife exposur Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Fractionation and bioaccumulation of perfluorooctane sulfonate (PFOS) isomers in a lake ontario fo Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Occurrence, profiles, and ecotoxicity of poly- and perfluoroalkyl substances and their alternatives in g Poly- And Perfluoroalkyl Substances in Seawater and Plankton from the Northwestern Atlantic Margi Poly- And Perfluoroalkyl Substances in Seawater and Plankton from the Northwestern Atlantic Margi Poly- And Perfluoroalkyl Substances in Seawater and Plankton from the Northwestern Atlantic Margi Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Fluorine Mass Balance and Suspect Screening in Marine Mammals from the Northern Hemisphere Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1 Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Absorption, distribution, metabolism, and excretion of [1-14C]-perfluorohexanoate ([14C]-PFHx) in r Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Toxicokinetics of Seven Perfluoroalkyl Sulfonic and Carboxylic Acids in Pigs Fed a Contaminated Diet Elimination kinetics of perfluorohexanoic acid in humans and comparison with mouse, rat and monk Elimination kinetics of perfluorohexanoic acid in humans and comparison with mouse, rat and monk Elimination kinetics of perfluorohexanoic acid in humans and comparison with mouse, rat and monk Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Identification, Tissue Distribution, and Bioaccumulation Potential of Cyclic Perfluorinated Sulfonic A Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Tissue distribution of 14C-labelled perfluorooctanoic acid in adult mice after 1-5 days of dietary ex Short-chain Polyfluoroalkyl Substances (PFAS) -A literature review of information on human health effects and environmen Long-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of Short- Long-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortLong-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortLong-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortLong-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortLong-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortLong-Chain Perfluoroalkyl acids (PFAAs) Affect the Bioconcentration and Tissue Distribution of ShortOccurrence and risk of chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) in seafood from ma Occurrence and risk of chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) in seafood from ma Occurrence and risk of chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) in seafood from ma Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2 Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2 Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2 Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2 Aquatic hazard, bioaccumulation and screening risk assessment for ammonium 2,3,3,3-tetrafluoro-2 Tissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FTissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid FFirst Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in First Report on the Bioaccumulation and Trophic Transfer of Perfluoroalkyl Ether Carboxylic Acids in Dietary bioaccumulation of perfluorophosphonates and perfluorophosphinates in juvenile rainbow t Dietary bioaccumulation of perfluorophosphonates and perfluorophosphinates in juvenile rainbow t Dietary bioaccumulation of perfluorophosphonates and perfluorophosphinates in juvenile rainbow t Evaluation of using mobility of chemicals in the environment to fulfil bioaccumulation criteria of the Stockholm Conventio Evaluation of using mobility of chemicals in the environment to fulfil bioaccumulation criteria of the Stockholm Conventio Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( Analysis of the presence of perfluoroalkyl substances in water, sediment and biota of the Jucar River ( The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) The Madrid statement on poly-and perfluoroalkyl substances (PFASs) Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persiste Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persiste Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persiste Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persiste Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persiste secondary-title C9-C14 PFCAs including their salts and precursors phonic acid and its salts as Substances of Very High Concern because of their vPvB (article 57e) properties Perfluorooctanoic acid (PFOA), PFOA salts and PFOA-related substances noin acid (PFOA) as a substance of very high concern ic acid (PFOA) as a substance of very high concern because of its CMR and PBT properties ecanoic acid as a substance of very high concern because of its vPvB properties Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environ.Toxicol.Chem Environ.Toxicol.Chem Environ.Toxicol.Chem Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances The Journal of Toxicological Sciences The Journal of Toxicological Sciences Mar Pollut Bull Mar Pollut Bull Mar Pollut Bull Environmental Pollution Environmental Pollution Environmental Pollution Environmental Pollution Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environmental Toxicology and Chemistry Environment International Environment International Environment International Environment International Environment International Environment International Environmental Science & Technology Environmental Science & Technology Environmental Science & Technology Environmental Science & Technology Environmental Science & Technology Environmental Science and Technology Environmental Science and Technology Environmental Science and Technology Toxicology Toxicology Toxicology Toxicology Toxicology Environmental Science and Technology Environmental Science and Technology Environmental science & technology Environmental science & technology Environmental science & technology Environmental science & technology Environmental science & technology Regulatory Toxicology and Pharmacology Regulatory Toxicology and Pharmacology Regulatory Toxicology and Pharmacology Regulatory Toxicology and Pharmacology Toxicological Sciences Toxicological Sciences Toxicological Sciences Toxicological Sciences Toxicological Sciences Toxicological Sciences Toxicological Sciences Aquatic Toxicology Aquatic Toxicology Aquatic Toxicology Aquatic Toxicology Aquatic Toxicology Book Environmental and Health Risk Assessment of Perfluoroalkylated and Polyfluoroalkylated Substances (PFASs) in Swed Book Environmental and Health Risk Assessment of Perfluoroalkylated and Polyfluoroalkylated Substances (PFASs) in Swed Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Environmental Toxicology and Pharmacology Endocrinology Endocrinology Endocrinology Endocrinology Environ. 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2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2008 Mrz 9, 2008 2008 Mrz 9, 2008 2008 Mrz 9, 2008 2015 2015 2015 2015 2015 2015 2003 2003 2003 2003 2009 April 2009 2009 April 2009 2009 April 2009 2021 2021 2021 2021 2021 2021 pages 161 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 631-657 1 1 1 151-175 151-175 151-175 49-57 49-57 520-5 520-5 520-5 ylated Substances (PFASs) in Sweden (Editor ed.^eds.), 2021 2021 2003 2003 2003 2003 2003 2003 2003 2003 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2018 April 17, 2018 2018 April 17, 2018 2018 April 17, 2018 2018 April 17, 2018 2018 April 17, 2018 2012 2012 2012 2012 2012 2012 2002 2002 2002 2002 2002 2002 2002 2002 2002 2002 2013 Juli 2, 2013 2013 Juli 2, 2013 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2019 2019 2019 2019 2019 2019 2019 2019 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2012 2012 196-204 196-204 196-204 196-204 4592-4600 4592-4600 4592-4600 4592-4600 4592-4600 12285-12286 12285-12286 12285-12286 175-185 175-185 175-185 175-185 175-185 7214-23 7214-23 5051-5061 5051-5061 5051-5061 5051-5061 5051-5061 239-250 239-250 239-250 239-250 84-95 84-95 84-95 84-95 84-95 84-95 84-95 65-73 65-73 65-73 65-73 65-73 ylated Substances (PFASs) in Sweden (Editor ed.^eds.), 2012 2012 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2007 September 1, 2007 2008 Januar 3, 2008 2008 Januar 3, 2008 2008 Januar 3, 2008 2008 Januar 3, 2008 2005 2005 2005 2005 2005 2005 2005 2005 2005 2005 2005 2005 2005 2005 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2021 Dezember 7, 2021 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2007 Februar 2007 2007 Februar 2007 2003 2003 134-139 134-139 134-139 134-139 134-139 134-139 134-139 134-139 988-994 988-994 988-994 988-994 7439 7439 7439 7439 7439 7439 7439 12527 12527 12527 12527 12527 12527 12527 12527 12527 452-461 452-461 775-781 2003 2003 2003 2003 2003 2003 2015 Oktober 20, 2015 2015 Oktober 20, 2015 2013 2013 2013 2013 2013 2013 2019 2019 2019 2019 2019 2019 2019 2019 2012 2012 2012 2012 2012 2012 2011 2011 2011 2011 2011 2011 2011 2011 2019 2019 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2009 2009 2009 2009 2009 2009 2009 2009 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2003 Januar 2003 2003 Januar 2003 2003 Januar 2003 2003 Januar 2003 2003 2003 2003 2003 2003 2003 2003 2003 2021 Mrz 1, 2021 2021 Mrz 1, 2021 775-781 775-781 775-781 12306-14 12306-14 11293-11301 11293-11301 11293-11301 1852-1863 1852-1863 1852-1863 1852-1863 12285-12286 12285-12286 12285-12286 2423-2430 2423-2430 2423-2430 2423-2430 760-770 217-227 217-227 217-227 217-227 217-227 305-314 305-314 305-314 305-314 1669-1677 1669-1677 1669-1677 1669-1677 1669-1677 1669-1677 1669-1677 1669-1677 1669-1677 189-195 189-195 189-195 189-195 910-920 910-920 2021 Mrz 1, 2021 2019 2019 2019 2019 2019 2019 2019 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2019 Juni 4, 2019 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2013 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2010 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2013 September 1, 2013 2013 September 1, 2013 2013 September 1, 2013 2013 September 1, 2013 2013 September 1, 2013 910-920 1852-1863 1852-1863 1852-1863 1852-1863 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 6529-6538 7974 7974 7974 7974 7974 7974 7974 1957-1966 1957-1966 1957-1966 1957-1966 1957-1966 1957-1966 1957-1966 763-770 763-770 763-770 763-770 763-770 763-770 763-770 354-362 354-362 354-362 354-362 354-362 ites. Strategic Environmental Research and Develop 2013 September 1, 2013 2013 September 1, 2013 2014 2014 2014 2014 2014 2014 2014 2014 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2004 Oktober 2004 2004 Oktober 2004 2016 2016 2016 2016 2016 2016 2004 Oktober 2004 2004 Oktober 2004 2004 Oktober 2004 2016 2016 2016 2016 2016 2016 2017 2017 2017 2017 2017 2017 2007 2007 2007 2007 2018 Mai 1, 2018 2018 Mai 1, 2018 2018 Mai 1, 2018 2018 Mai 1, 2018 2018 Mai 1, 2018 2018 Mai 1, 2018 2017 Juni 1, 2017 2017 Juni 1, 2017 2017 Juni 1, 2017 2017 Juni 1, 2017 2017 Juni 1, 2017 2017 Juni 1, 2017 2020 2020 2011 2011 2011 2011 2011 2011 2011 2011 354-362 354-362 4637-4648 4637-4648 1921-1929 1921-1929 595-603 595-603 595-603 595-603 595-603 595-603 595-603 595-603 595-603 2343-55 2343-55 33-41 33-41 33-41 2324-2336 2324-2336 2324-2336 7029-7036 7029-7036 7029-7036 11085-11095 11085-11095 11085-11095 1803 1803 1235-1251 1235-1251 1235-1251 1235-1251 1235-1251 1235-1251 1483-1492 1483-1492 1483-1492 1483-1492 1483-1492 1483-1492 389-398 389-398 389-398 389-398 2011 2011 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2013 Januar 1, 2013 2013 Januar 1, 2013 2013 Januar 1, 2013 2013 Januar 1, 2013 2014 2014 2014 2014 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2008 Mrz 2008 2018 2018 2018 2018 2010 April 28, 2010 2010 April 28, 2010 2010 April 28, 2010 2011 Februar 2011 2011 Februar 2011 2017 2017 2017 2017 2017 2017 389-398 882-897 882-897 882-897 882-897 882-897 882-897 882-897 882-897 115-128 115-128 115-128 115-128 4637 4637 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 564-605 3-14 3-14 3-14 3-14 3-14 3-14 3-14 3-14 3-14 105-119 105-119 3746-3751 3746-3751 3746-3751 391-7 391-7 8450-8459 8450-8459 8450-8459 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2018 2018 2018 2018 2018 2018 2018 2018 2018 2018 2018 2018 2006 Dezember 1, 2006 2006 Dezember 1, 2006 2016 2016 2016 2016 2016 2016 2013 2013 2013 2013 2013 2013 2013 2013 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2012 Mai 2012 2012 Mai 2012 2012 Mai 2012 2012 Mai 2012 2012 Mai 2012 2012 Mai 2012 2012 Mai 2012 2019 2019 2019 2019 2019 2019 2019 2019 2019 2019 2019 2019 2019 2019 2014 2014 2014 2014 2020 November 1, 2020 8450-8459 8450-8459 8450-8459 8450-8459 8450-8459 8450-8459 8450-8459 251-259 251-259 251-259 251-259 251-259 251-259 257-297 257-297 33-41 33-41 33-41 1589-1596 1589-1596 1589-1596 1589-1596 258-265 258-265 258-265 258-265 258-265 258-265 258-265 258-265 258-265 672-80 672-80 672-80 672-80 672-80 672-80 672-80 137-145 137-145 137-145 137-145 137-145 137-145 137-145 4637-4648 4637-4648 106037 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2020 November 1, 2020 2019 April 1, 2019 2019 April 1, 2019 2019 April 1, 2019 2019 April 1, 2019 2019 April 1, 2019 2019 April 1, 2019 2019 April 1, 2019 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2020 Mrz 1, 2020 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 106037 266-277 266-277 266-277 266-277 266-277 266-277 266-277 105358 105358 105358 105358 105358 105358 105358 105358 105358 105358 105358 22-31 22-31 22-31 22-31 22-31 22-31 22-31 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2001 2001 2001 2001 2014 2014 2014 2014 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2020 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 2019 Januar 1, 2019 1339-1342 1339-1342 1921-1929 1921-1929 6800-6811 6800-6811 6800-6811 6800-6811 6800-6811 6800-6811 6800-6811 7962-73 7962-73 7962-73 7962-73 240-271 240-271 240-271 240-271 240-271 240-271 240-271 240-271 240-271 240-271 240-271 2019 Januar 1, 2019 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2011 Oktober 1, 2011 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2019 Dezember 2019 2019 Dezember 2019 2019 Dezember 2019 2019 Dezember 2019 2019 Dezember 2019 2019 Dezember 2019 2019 Dezember 2019 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2021 Februar 15, 2021 2021 Februar 15, 2021 2021 Februar 15, 2021 2021 Februar 15, 2021 2021 Februar 15, 2021 2018 2018 2018 2018 2018 2018 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2014 2011 2011 2011 2011 2011 2011 240-271 8129-36 8129-36 8129-36 8129-36 8129-36 8129-36 2022-2029 2022-2029 2022-2029 2022-2029 2022-2029 2022-2029 2022-2029 2022-2029 124407 124407 124407 124407 124407 124407 124407 1247-1256 1247-1256 1247-1256 1247-1256 1247-1256 1247-1256 1247-1256 1247-1256 116355 116355 116355 116355 116355 335-341 335-341 335-341 2173-2182 2173-2182 2173-2182 2173-2182 2173-2182 2173-2182 2173-2182 5506-5513 5506-5513 5506-5513 2011 2011 2011 2011 2011 2011 2004 Oktober 15, 2004 2004 Oktober 15, 2004 2004 Oktober 15, 2004 2004 Oktober 15, 2004 2009 2009 2009 2009 2009 2009 2009 2009 2009 2009 2009 2009 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2019 2019 2019 2019 2019 2019 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2020 April 7, 2020 2009 2009 2009 2009 5506-5513 5506-5513 5506-5513 5379-5385 5379-5385 5379-5385 5379-5385 9397-9403 9397-9403 9397-9403 9397-9403 9397-9403 9397-9403 9397-9403 219-236 219-236 219-236 219-236 219-236 219-236 219-236 219-236 219-236 12348-12356 12348-12356 12348-12356 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 4046-4058 400-406 400-406 2009 2009 2009 2009 2009 2009 2009 2009 2011 2011 2011 2011 2011 2011 2011 2011 2011 2011 2011 2011 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2014 Juli 16, 2014 2013 November 2013 2013 November 2013 2013 November 2013 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2007 Januar 3, 2007 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2020 Januar 1, 2020 2020 Januar 1, 2020 2020 Januar 1, 2020 2020 Januar 1, 2020 2020 Januar 1, 2020 2020 Januar 1, 2020 2020 Januar 1, 2020 2015 2015 2017 2017 400-406 400-406 400-406 400-406 55-62 55-62 55-62 55-62 55-62 55-62 6861-6870 6861-6870 6861-6870 6861-6870 6861-6870 6861-6870 6861-6870 6861-6870 6861-6870 2419-25 2419-25 2419-25 1554-1559 1554-1559 1554-1559 1554-1559 1554-1559 1554-1559 1554-1559 1554-1559 1554-1559 10923-10932 10923-10932 10923-10932 10923-10932 10923-10932 10923-10932 10923-10932 10923-10932 124755 124755 124755 124755 124755 124755 124755 12358-12368 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2017 2020 Juli 15, 2020 2020 Juli 15, 2020 2020 Juli 15, 2020 2016 April 2016 2016 April 2016 2016 April 2016 2016 April 2016 2016 April 2016 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2021 2012 Mrz 20, 2012 2012 Mrz 20, 2012 2012 Mrz 20, 2012 2018 2018 2018 2018 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2016 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 2015 12358-12368 12358-12368 12358-12368 12358-12368 12358-12368 12358-12368 138538 138538 138538 336-42 336-42 336-42 336-42 336-42 14156-14165 14156-14165 14156-14165 14156-14165 14156-14165 14156-14165 14156-14165 3489-97 3489-97 3489-97 503-512 503-512 503-512 503-512 503-512 503-512 A107-A111 A107-A111 A107-A111 A107-A111 A107-A111 A107-A111 A107-A111 A107-A111 A107-A111 2015 2015 2008 Februar 1, 2008 2008 Februar 1, 2008 2008 Februar 1, 2008 2008 Februar 1, 2008 2008 Februar 1, 2008 A107-A111 995-1003 995-1003 995-1003 995-1003 995-1003 pub-location https://echa.europa.eu/documents/10162/86f13df6-a078-475c-b0b2-2eb9536ebc5d Cham Cham Cham City City Environmental project No. 1707, 2015 isbn ED/169/2012 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 07307268 (ISSN) 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 0730-7268 978-3-319-15518-0 978-3-319-15518-0 978-3-319-15518-0 1879-3363 (Electronic) 0025-326X (Linking) 1879-3363 (Electronic) 0025-326X (Linking) 1879-3363 (Electronic) 0025-326X (Linking) 02697491 (ISSN) 02697491 (ISSN) 02697491 (ISSN) 02697491 (ISSN) 01604120 (ISSN) 01604120 (ISSN) 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for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife We synthesize current understanding of the magnitudes and methods for assessing human and wildlife Perfluorooctanoate (PFOA) and other perfluorocarboxylates (PFCAs) are widely dispersed in the environment. Current and Perfluorooctanoate (PFOA) and other perfluorocarboxylates (PFCAs) are widely dispersed in the environment. Current and Perfluorooctanoate (PFOA) and other perfluorocarboxylates (PFCAs) are widely dispersed in the environment. Current and Perfluoroalkyl acids (PFAAs) are highly persistent and widely spread in the environment. PFAAs were Perfluoroalkyl acids (PFAAs) are highly persistent and widely spread in the environment. PFAAs were Perfluoroalkyl acids (PFAAs) are highly persistent and widely spread in the environment. PFAAs were Perfluorooctanoic acid (PFOA) is an octanoic acid derivative to which all aliphatic hydrocarbons are Perfluorooctanoic acid (PFOA) is an octanoic acid derivative to which all aliphatic hydrocarbons are Total body burden and tissue distribution of polyfluorinated compounds (PFCs) were investigated in harbor seals (Phoca vi Total body burden and tissue distribution of polyfluorinated compounds (PFCs) were investigated in harbor seals (Phoca vi Total body burden and tissue distribution of polyfluorinated compounds (PFCs) were investigated in harbor seals (Phoca vi Tissue distribution of legacy and emerging per-and polyfluoroalkyl substances (PFASs) in several kind Tissue distribution of legacy and emerging per-and polyfluoroalkyl substances (PFASs) in several kind Tissue distribution of legacy and emerging per-and polyfluoroalkyl substances (PFASs) in several kind Tissue distribution of legacy and emerging per-and polyfluoroalkyl substances (PFASs) in several kind The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum The emergence of novel per- and polyfluoroalkyl substances (PFASs) has enabled researchers to determine their bioaccum Perfluorinated alkyl acids (PFAAs) are important global pollutants with unique pharmacokinetics. Evidence is accumulating Perfluorinated alkyl acids (PFAAs) are important global pollutants with unique pharmacokinetics. Evidence is accumulating Toxicokinetics are important for extrapolating health effects and effect levels observed in laboratory animals to humans fo Toxicokinetics are important for extrapolating health effects and effect levels observed in laboratory animals to humans fo Toxicokinetics are important for extrapolating health effects and effect levels observed in laboratory animals to humans fo Toxicokinetics are important for extrapolating health effects and effect levels observed in laboratory animals to humans fo Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are detected in the environment and, more specifically, Exposure measurement data from several developed countries indicate that human beings are widely exposed to low leve Exposure measurement data from several developed countries indicate that human beings are widely exposed to low leve Exposure measurement data from several developed countries indicate that human beings are widely exposed to low leve Exposure measurement data from several developed countries indicate that human beings are widely exposed to low leve A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he A feeding study was performed to examine the bioaccumulation of per- and polyfluoroalkyl substances (PFAS) in laying he 8-2 Fluorotelomer alcohol (FTOH) and its metabolites, perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA), a 8-2 Fluorotelomer alcohol (FTOH) and its metabolites, perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA), a Methods to predict the bioaccumulation potential of per- and polyfluorinated alkyl substances (PFAS) are sorely needed, g Methods to predict the bioaccumulation potential of per- and polyfluorinated alkyl substances (PFAS) are sorely needed, g Perfluorinated acids (PFAs) recently have emerged as persistent global contaminants after their detection in wildlife and h Perfluorinated acids (PFAs) recently have emerged as persistent global contaminants after their detection in wildlife and h Perfluorinated acids (PFAs) recently have emerged as persistent global contaminants after their detection in wildlife and h Perfluorinated acids (PFAs) recently have emerged as persistent global contaminants after their detection in wildlife and h Abstract Perfluoroalkyl acids (PFAAs) mostly exist as ionic compounds that are of major concern because of their accumula Abstract Perfluoroalkyl acids (PFAAs) mostly exist as ionic compounds that are of major concern because of their accumula Abstract Perfluoroalkyl acids (PFAAs) mostly exist as ionic compounds that are of major concern because of their accumula Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Information on placental transfer and adverse outcomes of short-chain per- and polyfluoroalkyl subst Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Per- and polyfluoroalkyl substances (PFAS) are synthetic, organic chemicals that resist environmental breakdown. The prop Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both Perfluorooctane sulfonate (PFOS; C8F17SO) bioaccumulation and toxicity have been demonstrated in both The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w The role of milk in the transfer of perfluoroalkyl substances (PFASs) to offspring is not well known in wildlife. Eight PFASs w Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Perfluoroalkyl substances (PFASs) are environmental pollutants with an important bioaccumulation potential. However, th Polyfluoroalkyl and perfluoroalkyl substances (PFASs) are distributed ubiquitously in the aquatic environment, which raises Polyfluoroalkyl and perfluoroalkyl substances (PFASs) are distributed ubiquitously in the aquatic environment, which raises Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu Per- and poly-fluoroalkyl substances (PFAS) are ubiquitously distributed throughout aquatic environments and can bioaccu The present study examines a new bioaccumulation model for hydrophobic organic chemicals in aquatic food webs. The p The present study examines a new bioaccumulation model for hydrophobic organic chemicals in aquatic food webs. The p Methods for the regulatory assessment of the bioaccumulation potential of organic chemicals are founded on empirical m Methods for the regulatory assessment of the bioaccumulation potential of organic chemicals are founded on empirical m Methods for the regulatory assessment of the bioaccumulation potential of organic chemicals are founded on empirical m Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract To support the goals articulated in the vision for exposure and risk assessment in the twenty-first century, we hig Abstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of diAbstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of diAbstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of diAbstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of diAbstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of diAbstract The present study applies a chemical activity?based approach to: 1) evaluate environmental concentrations of di- Environmental contextPoly- and perfluorinated alkyl substances (PFASs) include a wide range of indiv Environmental contextPoly- and perfluorinated alkyl substances (PFASs) include a wide range of indiv Environmental contextPoly- and perfluorinated alkyl substances (PFASs) include a wide range of indiv Environmental contextPoly- and perfluorinated alkyl substances (PFASs) include a wide range of indiv Environmental contextPoly- and perfluorinated alkyl substances (PFASs) include a wide range of indiv Abstract A mechanistic mass balance bioconcentration model is developed and parameterized for ionogenic organic chem Abstract A mechanistic mass balance bioconcentration model is developed and parameterized for ionogenic organic chem Abstract A mechanistic mass balance bioconcentration model is developed and parameterized for ionogenic organic chem Abstract A mechanistic mass balance bioconcentration model is developed and parameterized for ionogenic organic chem Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to h The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The perfluoroalkyl acid salts (both carboxylates and sulfonates, hereafter designated as PFAAs) and their derivatives are im The distribution of 15 perfluorinated compounds (PFCs) among eel (Anguilla anguilla), sediment, and water was investigate The distribution of 15 perfluorinated compounds (PFCs) among eel (Anguilla anguilla), sediment, and water was investigate The distribution of 15 perfluorinated compounds (PFCs) among eel (Anguilla anguilla), sediment, and water was investigate This paper reports on the partitioning behaviour of 15 perfluorinated compounds (PFCs), including C(4)-C(10) sulfonates an This paper reports on the partitioning behaviour of 15 perfluorinated compounds (PFCs), including C(4)-C(10) sulfonates an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an This study assessed the aquatic toxicity and bioaccumulation potential of 6:2 fluorotelomer sulfonate (6:2 FTSA). Acute an Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Carp (Cyprinus carpio L.) was exposed to perfluorinated compounds (PFCs)-perfluoroalkyl carboxylic acids (number of carb Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia Poly- and perfluoroalkyl substances (PFAS) are ubiquitous contaminants that can bioaccumulate in aquatic taxa. Amphibia While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro While new chemicals have replaced major toxic legacy contaminants such as polychlorinated biphenyls (PCBs) and dichloro Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Concentrations of 11 PFASs were determined in muscle and whole fish for six species collected from Charleston, South Car Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Per- and polyfluoroalkyl substances (PFAS) are anthropogenic chemicals of concern that persist in the environment. Enviro Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluoroalkyl substances (PFASs) is a growing class of contaminants in the Arctic environment, and include the established Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Perfluorinated alkyl substances (PFASs) are global, persistent, and toxic contaminants. We assessed PFAS concentrations in green (Chelonia mydas) and hawksbill (Eretmochelys imbricata) turtles from the North Pacific. Fifteen compounds were quantified via liquid chromatography tandem mass spectrometry from 62 green turtle and 6 hawksbill plasma samples from Hawai'i, Palmyra Atoll, and the Northern Marianas Islands. Plasma from 14 green turtles severely afflicted with fibropapillomatosis, and eggs from 12 Hawaiian hawksbill nests from 7 females were analyzed. Perfluorooctane sulfonate (PFOS) predominated in green turtle plasma; perfluorononanoic acid (PFNA) predominated in hawksbill tissues. Concentrations were greater in hawksbill than green turtle plasma (p < 0.05), related to trophic differences. Green turtle plasma PFOS concentrations were related to human populations from highest to lowest: Hawai'i, Marianas, Palmyra. Influence on fibropapillomatosis was not evident. PFASs were maternally transferred to hawksbill eggs, with decreasing concentrations with distance from airports and with clutch order from one female. A risk assessment of PFOS showed concern for immunosuppression in Kailua green turtles and alarming concern for hawksbill developmental toxicity. Perfluoroundecanoic (PFUnA) and perfluorotridecanoic (PFTriA) acid levels were correlated with reduced emergence success (p < 0.05). Studies to further examine PFAS effects on sea turtle development would be beneficial. 2021 Elsevier Ltd Endangered or threatened sea turtle species at remote Pacific islands contain perfluoroalkyl substances in blood and offload them to eggs, at concentrations known to be detrimental in birds. 2021 Elsevier Ltd Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t Per-and polyfluoroalkyl substances (PFASs) have attracted scientific and regulatory attention due t The goal of this article is to summarize new biological monitoring information on perfluorinated compounds (PFCs) in aqua The goal of this article is to summarize new biological monitoring information on perfluorinated compounds (PFCs) in aqua The goal of this article is to summarize new biological monitoring information on perfluorinated compounds (PFCs) in aqua The goal of this article is to summarize new biological monitoring information on perfluorinated compounds (PFCs) in aqua Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Poly- and perfluoroalkyl substances (PFASs) are important environmental contaminants globally and in the early 2000s the Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Wildlife from remote locations have been shown to bioaccumulate perfluorinated compounds (PFCs) in their tissues. Twel Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic orga The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc The widespread use of perfluoroalkylated acids (PFAAs) has led to a global presence in the environment, in which they acc Perfluoroalkyl acids (PFAAs) are a focus of scientific and regulatory attention nowadays. However, PFAAs dynamics in the e Perfluoroalkyl acids (PFAAs) are a focus of scientific and regulatory attention nowadays. However, PFAAs dynamics in the e Perfluoroalkyl acids (PFAAs) are a focus of scientific and regulatory attention nowadays. However, PFAAs dynamics in the e Perfluoroalkyl acids (PFAAs) are a focus of scientific and regulatory attention nowadays. However, PFAAs dynamics in the e Perfluoroalkyl acids (PFAAs) are a focus of scientific and regulatory attention nowadays. However, PFAAs dynamics in the e Releases of Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) associated with Aqueous Film Forming Foams (AFFFs) ha Releases of Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) associated with Aqueous Film Forming Foams (AFFFs) ha Releases of Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) associated with Aqueous Film Forming Foams (AFFFs) ha Perfluorooctane sulfonate (PFOS) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlif Perfluorooctane sulfonate (PFOS) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlif Perfluorooctane sulfonate (PFOS) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlif Perfluorooctane sulfonate (PFOS) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlif Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos Certain poly- and perfluoroalkyl substances (PFASs) exhibit significant bioaccumulation/biomagnification behaviors in ecos The ocean is thought to be the terminal sink for poly- and perfluoroalkyl substances (PFAS) that ha The ocean is thought to be the terminal sink for poly- and perfluoroalkyl substances (PFAS) that ha The ocean is thought to be the terminal sink for poly- and perfluoroalkyl substances (PFAS) that ha The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprag The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The absorption, tissue distribution, elimination, and metabolism of [1-14C]-PFHx in rats and mice dosed orally at 2 or 100 m The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig The transfer of a mixture of perfluoroalkyl acids (PFAAs) from contaminated feed into the edible tissues of 24 fattening pig Major fluorinated chemical manufacturers have developed new short-chain per- and polyfluorinated substances with mor Major fluorinated chemical manufacturers have developed new short-chain per- and polyfluorinated substances with mor Major fluorinated chemical manufacturers have developed new short-chain per- and polyfluorinated substances with mor Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Individual whole body homogenates of 4 year old lake trout (Salvelinus namaycush) samples collected in 2001 from each o Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev Perfluorooctanoic acid (PFOA), a global environmental pollutant detected in both wildlife and human populations, has sev In recent years, chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name: F-53B), one of the alternatives to pe In recent years, chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name: F-53B), one of the alternatives to pe In recent years, chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA, trade name: F-53B), one of the alternatives to pe The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more The fluoropolymer manufacturing industry is moving to alternative polymerization processing aid technologies with more As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h As novel alternatives to legacy poly- and perfluoroalkyl substances (PFAS), perfluoroalkyl ether carboxylic acids (PFECAs) h The perfluorophosphonates (PFPAs) and perfluorophosphinates (PFPiAs) are high production volume chemicals that have The perfluorophosphonates (PFPAs) and perfluorophosphinates (PFPiAs) are high production volume chemicals that have The perfluorophosphonates (PFPAs) and perfluorophosphinates (PFPiAs) are high production volume chemicals that have The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s The presence, sources and partitioning of 21 perfluoroalkyl substances (PFASs: C4-C14, C16, C18 carboxylate, C4, C6-C10 s remote-database-name language Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English in the environment. Current and/or historical production of in the environment. Current and/or historical production of in the environment. Current and/or historical production of Springer Link en Springer Link en Springer Link en J-Stage J-Stage stigated in harbor seals (Phoca vitulina) from the German Bight in 2007. A total number of 18 individual PFCs from the following group stigated in harbor seals (Phoca vitulina) from the German Bight in 2007. A total number of 18 individual PFCs from the following group stigated in harbor seals (Phoca vitulina) from the German Bight in 2007. A total number of 18 individual PFCs from the following group Scopus English Scopus English Scopus English Scopus English hers to determine their bioaccumulation, whicEhniglish hers to determine their bioaccumulation, whicEhniglish hers to determine their bioaccumulation, whicEhniglish hers to determine their bioaccumulation, whicEhniglish hers to determine their bioaccumulation, whicEhniglish hers to determine their bioaccumulation, whicEhniglish kinetics. Evidence is accumulating that their behavior within organisms is affected by interaction with a number of proteins. In mamma kinetics. Evidence is accumulating that their behavior within organisms is affected by interaction with a number of proteins. In mamma laboratory animals to humans for purposes oEnglish laboratory animals to humans for purposes oEnglish laboratory animals to humans for purposes oEnglish laboratory animals to humans for purposes oEnglish ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has ironment and, more specifically, in wildlife and humans. The large variation in the reported biological half-lives for PFOA and PFOS has gs are widely exposed to low levels of the synthetic xenoestro gs are widely exposed to low levels of the synthetic xenoestro gs are widely exposed to low levels of the synthetic xenoestro gs are widely exposed to low levels of the synthetic xenoestro kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English kyl substances (PFAS) in laying hens' tissues a English perfluorononanoic acid (PFNA), are developmental toxicant perfluorononanoic acid (PFNA), are developmental toxicant ances (PFAS) are sorely needed, given the proliferation of these substances and lack of data on their properties and behavior. Here, we ances (PFAS) are sorely needed, given the proliferation of these substances and lack of data on their properties and behavior. Here, we r their detection in wildlife and humans from various geogr r their detection in wildlife and humans from various geogr r their detection in wildlife and humans from various geogr r their detection in wildlife and humans from various geogr oncern because of their accumulative behavior. The discussio oncern because of their accumulative behavior. The discussio oncern because of their accumulative behavior. The discussio ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications ACS Publications vironmental breakdown. The properties that mEanglish vironmental breakdown. The properties that mEanglish vironmental breakdown. The properties that mEanglish vironmental breakdown. The properties that mEanglish vironmental breakdown. The properties that mEanglish vironmental breakdown. The properties that mEanglish Wiley Online Library en Wiley Online Library en Wiley Online Library en Wiley Online Library en Wiley Online Library en Wiley Online Library en Wiley Online Library en l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English l known in wildlife. Eight PFASs were qua English umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 umulation potential. However, their metabolism and distribution in humans are not well studied. In this study, the concentrations of 2 aquatic environment, which raises concern f English aquatic environment, which raises concern f English tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish tic environments and can bioaccumulate in orEnglish micals in aquatic food webs. The purpose of the model is to provide site-specific estimates of chemical concentrations and associated b micals in aquatic food webs. The purpose of the model is to provide site-specific estimates of chemical concentrations and associated b micals are founded on empirical measurements and mechanistic mod micals are founded on empirical measurements and mechanistic mod micals are founded on empirical measurements and mechanistic mod n the twenty-first century, we highlight the application n the twenty-first century, we highlight the application n the twenty-first century, we highlight the application n the twenty-first century, we highlight the application n the twenty-first century, we highlight the application n the twenty-first century, we highlight the application vironmental concentrations of di-ethylhexyl phthalate (DEHP vironmental concentrations of di-ethylhexyl phthalate (DEHP vironmental concentrations of di-ethylhexyl phthalate (DEHP vironmental concentrations of di-ethylhexyl phthalate (DEHP vironmental concentrations of di-ethylhexyl phthalate (DEHP vironmental concentrations of di-ethylhexyl phthalate (DEHP Scopus Scopus Scopus Scopus Scopus rized for ionogenic organic chemicals (IOCs) in fish and evaluat rized for ionogenic organic chemicals (IOCs) in fish and evaluat rized for ionogenic organic chemicals (IOCs) in fish and evaluat rized for ionogenic organic chemicals (IOCs) in fish and evaluat emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish emicals of potential concern to human healthEanglish FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that FAAs) and their derivatives are important chemicals that diment, and water was investigated for 21 locations in The diment, and water was investigated for 21 locations in The diment, and water was investigated for 21 locations in The including C(4)-C(10) sulfonates and C(5)-C(14) carboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus including C(4)-C(10) sulfonates and C(5)-C(14) carboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus cdnsciencepub.com (Atypon) cdnsciencepub.com (Atypon) er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G er sulfonate (6:2 FTSA). Acute and chronic aquatic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to G carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes carboxylic acids (number of carbon atoms, C = 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tes mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish mulate in aquatic taxa. Amphibians are particuEnglish ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ated biphenyls (PCBs) and dichlorodiphenyltrichloroethane (DDT), knowledge of their current levels and biomagnification potential in B ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ected from Charleston, South Carolina (SC) for the assessment of potential health risks to humans and wildlife. Across all species and c ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ment, and include the established perfluor English ment, and include the established perfluor English ment, and include the established perfluor English ment, and include the established perfluor English ment, and include the established perfluor English ment, and include the established perfluor English ment, and include the established perfluor English English English English English English English English English English English English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English Scopus English inated compounds (PFCs) in aquatic ecosystems (post-2005) as a followup to our critical review published in 2006. A wider range of ge inated compounds (PFCs) in aquatic ecosystems (post-2005) as a followup to our critical review published in 2006. A wider range of ge inated compounds (PFCs) in aquatic ecosystems (post-2005) as a followup to our critical review published in 2006. A wider range of ge inated compounds (PFCs) in aquatic ecosystems (post-2005) as a followup to our critical review published in 2006. A wider range of ge ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en ScienceDirect en unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo unds (PFCs) in their tissues. Twelve PFCs, consisting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluo rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically rticularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically e environment, in which they accumulate andemng e environment, in which they accumulate andemng e environment, in which they accumulate andemng e environment, in which they accumulate andemng e environment, in which they accumulate andemng e environment, in which they accumulate andemng e environment, in which they accumulate andemng However, PFAAs dynamics in the environment eangd the factors that determine wildlife exposure are still not well understood. In this stu However, PFAAs dynamics in the environment eangd the factors that determine wildlife exposure are still not well understood. In this stu However, PFAAs dynamics in the environment eangd the factors that determine wildlife exposure are still not well understood. In this stu However, PFAAs dynamics in the environment eangd the factors that determine wildlife exposure are still not well understood. In this stu However, PFAAs dynamics in the environment eangd the factors that determine wildlife exposure are still not well understood. In this stu us Film Forming Foams (AFFFs) have the potenEtinaglish us Film Forming Foams (AFFFs) have the potenEtinaglish us Film Forming Foams (AFFFs) have the potenEtinaglish detectable in humans and wildlife worldwide that has alert detectable in humans and wildlife worldwide that has alert detectable in humans and wildlife worldwide that has alert detectable in humans and wildlife worldwide that has alert iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish iomagnification behaviors in ecosystems. PFASEnglish Scopus Scopus Scopus id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo id (PFBS) were evaluated in Sprague-Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS follo nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra nd mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in ra e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC e edible tissues of 24 fattening pigs was investigated. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFC yfluorinated substances with more favorable environmental, health and safety profiles. This study provides the first evaluation of the e yfluorinated substances with more favorable environmental, health and safety profiles. This study provides the first evaluation of the e yfluorinated substances with more favorable environmental, health and safety profiles. This study provides the first evaluation of the e ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra ples collected in 2001 from each of the Great Lakes were extra and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and and human populations, has several pathophysiological effects in experimental animals, including hepatotoxicity, immunotoxicity, and 3B), one of the alternatives to perfluorooctane sulfonate (PFOS), has been widely detected in environmental matrices and organisms i 3B), one of the alternatives to perfluorooctane sulfonate (PFOS), has been widely detected in environmental matrices and organisms i 3B), one of the alternatives to perfluorooctane sulfonate (PFOS), has been widely detected in environmental matrices and organisms i ssing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of longssing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of longssing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of longssing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of longssing aid technologies with more favorable toxicological and environmental profiles as part of a commitment to curtail the use of long- ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English ether carboxylic acids (PFECAs) have been English tion volume chemicals that have been observed in Canadian surface waters and wastewater environments. To examine whether their tion volume chemicals that have been observed in Canadian surface waters and wastewater environments. To examine whether their tion volume chemicals that have been observed in Canadian surface waters and wastewater environments. To examine whether their 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish 16, C18 carboxylate, C4, C6-C10 sulfonates andEnglish research-notes Citation Key: 725 Citation Key: 725 Citation Key: 725 DOI: 10.1007/978-3-319-15518-0_6 DOI: 10.1007/978-3-319-15518-0_6 DOI: 10.1007/978-3-319-15518-0_6 e German Bight in 2007. A total number of 18 individual PFCs from the following groups could be quantified in the different tissues: pe e German Bight in 2007. A total number of 18 individual PFCs from the following groups could be quantified in the different tissues: pe e German Bight in 2007. A total number of 18 individual PFCs from the following groups could be quantified in the different tissues: pe publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd avior within organisms is affected by interaction with a number of proteins. In mammals, serum albumin, fatty acid binding proteins (FA avior within organisms is affected by interaction with a number of proteins. In mammals, serum albumin, fatty acid binding proteins (FA publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. Citation Key: Borg2012 Citation Key: Borg2012 humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has humans. The large variation in the reported biological half-lives for PFOA and PFOS has Citation Key: 55 Citation Key: 55 Citation Key: 55 Citation Key: 55 publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society Citation Key: 742 Citation Key: 742 eration of these substances and lack of data on their properties and behavior. Here, we test whether molecular docking, a technique w eration of these substances and lack of data on their properties and behavior. Here, we test whether molecular docking, a technique w Citation Key: 475 Citation Key: 475 Citation Key: 475 Citation Key: 475 Citation Key: Martin2003 Citation Key: Martin2003 Citation Key: Martin2003 Citation Key: Martin2003 publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: Elsevier B.V. publisher: Elsevier B.V. publisher: Elsevier B.V. publisher: Elsevier B.V. publisher: Elsevier B.V. publisher: Elsevier B.V. _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 _eprint: https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.257 publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 and distribution in humans are not well studied. In this study, the concentrations of 2 publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell model is to provide site-specific estimates of chemical concentrations and associated bioconcentration factors, bioaccumulation factors model is to provide site-specific estimates of chemical concentrations and associated bioconcentration factors, bioaccumulation factors Citation Key: 757 Citation Key: 757 Citation Key: 757 publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: John Wiley & Sons, Ltd publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell publisher: Wiley Blackwell Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 717 Citation Key: 2027 Citation Key: 2027 Citation Key: 2027 arboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus) in the Orge River (nearby Paris). Total PFC level arboxylic acids, between water, sediment and fish (European chub, Leuciscus cephalus) in the Orge River (nearby Paris). Total PFC level publisher: NRC Research Press publisher: NRC Research Press tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi tic hazard endpoints indicate 6:2 FTSA is not classified for aquatic hazard according to GHS or European CLP legislation. The aqueous bi 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF 8, 11, 12, 14, 16, and 18) and perfluorooctane sulfonate (PFOS)-in bioconcentration tests to compare the bioconcentration factors (BCF publisher: Academic Press publisher: Academic Press publisher: Academic Press publisher: Academic Press publisher: Academic Press publisher: Academic Press publisher: Academic Press oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch oroethane (DDT), knowledge of their current levels and biomagnification potential in Baltic Sea biota is lacking. Therefore, a suite of ch he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c he assessment of potential health risks to humans and wildlife. Across all species and c publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd (post-2005) as a followup to our critical review published in 2006. A wider range of geographical locations (e.g., South America, Russia (post-2005) as a followup to our critical review published in 2006. A wider range of geographical locations (e.g., South America, Russia (post-2005) as a followup to our critical review published in 2006. A wider range of geographical locations (e.g., South America, Russia (post-2005) as a followup to our critical review published in 2006. A wider range of geographical locations (e.g., South America, Russia ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo ting of perfluorinated carboxylic (PFCA) and sulfonic (PFSA) acids as well as the perfluorooctane sulfonate (PFOS) precursor perfluoroo gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically gions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically publisher: Elsevier Ltd publisher: Elsevier Ltd publisher: Elsevier Ltd Citation Key: 388 Citation Key: 388 Citation Key: 388 Citation Key: 388 Citation Key: Kelly2009 Citation Key: Kelly2009 Citation Key: Kelly2009 Citation Key: Kelly2009 Citation Key: Kelly2009 Citation Key: Kelly2009 publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: Chinese Academy of Sciences publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o s and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenous or oral (rat o uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con uated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a short time to maximum con ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss ted. Four perfluoroalkyl sulfonic (PFSAs) and three perfluoroalkyl carboxylic acids (PFCAs) were quantifiable in feed, plasma, edible tiss vironmental, health and safety profiles. This study provides the first evaluation of the elimination half-life of perfluorohexanoic acid (PF vironmental, health and safety profiles. This study provides the first evaluation of the elimination half-life of perfluorohexanoic acid (PF vironmental, health and safety profiles. This study provides the first evaluation of the elimination half-life of perfluorohexanoic acid (PF Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 Citation Key: 184 ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ological effects in experimental animals, including hepatotoxicity, immunotoxicity, and ulfonate (PFOS), has been widely detected in environmental matrices and organisms in China. However, sufficient information regardi ulfonate (PFOS), has been widely detected in environmental matrices and organisms in China. However, sufficient information regardi ulfonate (PFOS), has been widely detected in environmental matrices and organisms in China. However, sufficient information regardi ological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate t ological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate t ological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate t ological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate t ological and environmental profiles as part of a commitment to curtail the use of long-chain perfluoroalkyl acids (PFAAs). To facilitate t publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society in Canadian surface waters and wastewater environments. To examine whether their occurrence would result in contamination of org in Canadian surface waters and wastewater environments. To examine whether their occurrence would result in contamination of org in Canadian surface waters and wastewater environments. To examine whether their occurrence would result in contamination of org publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: Academic Press Inc. publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society publisher: American Chemical Society url https://doi.org/10.1007/978-3-319-15518-0_6 https://doi.org/10.1007/978-3-319-15518-0_6 https://doi.org/10.1007/978-3-319-15518-0_6 wing groups could be quantified in the different tissues: perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonates (PFSAs) wing groups could be quantified in the different tissues: perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonates (PFSAs) wing groups could be quantified in the different tissues: perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonates (PFSAs) https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076837193&doi=10.1016%2fj.envint.2019.105418&partnerID= In mammals, serum albumin, fatty acid binding proteins (FABPs) and organic anion transporters (OATs) have been identified as import In mammals, serum albumin, fatty acid binding proteins (FABPs) and organic anion transporters (OATs) have been identified as import https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065822586&doi=10.1016%2fj.yrtph.2019.05.008&partnerID=40 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065822586&doi=10.1016%2fj.yrtph.2019.05.008&partnerID=40 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065822586&doi=10.1016%2fj.yrtph.2019.05.008&partnerID=40 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065822586&doi=10.1016%2fj.yrtph.2019.05.008&partnerID=40 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://www.sciencedirect.com/science/article/pii/S1382668907000488 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://doi.org/10.1021/acs.est.1c03773 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095831345&doi=10.1021%2facs.jafc.0c04485&partnerID=40&m or. Here, we test whether molecular docking, a technique where interactions between proteins and ligands are simulated to predict bo or. Here, we test whether molecular docking, a technique where interactions between proteins and ligands are simulated to predict bo https://doi.org/10.1002/etc.4954 https://doi.org/10.1002/etc.4954 https://doi.org/10.1002/etc.4954 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://doi.org/10.1021/acs.est.9b00715 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101372174&doi=10.1016%2fj.scitotenv.2020.144795&partnerI https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101372174&doi=10.1016%2fj.scitotenv.2020.144795&partnerI https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101372174&doi=10.1016%2fj.scitotenv.2020.144795&partnerI 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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078731776&doi=10.1002%2fetc.4640&partnerID=40&md5=38 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078731776&doi=10.1002%2fetc.4640&partnerID=40&md5=38 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85078731776&doi=10.1002%2fetc.4640&partnerID=40&md5=38 ssociated bioconcentration factors, bioaccumulation factors, and biota-sediment accumulation factors in organisms of aquatic food we ssociated bioconcentration factors, bioaccumulation factors, and biota-sediment accumulation factors in organisms of aquatic food we https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.4091 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.3689 https://doi.org/10.1002/etc.2020 https://doi.org/10.1002/etc.2020 https://doi.org/10.1002/etc.2020 https://doi.org/10.1002/etc.2020 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096680014&doi=10.1002%2fetc.4869&partnerID=40&md5=0f2 us cephalus) in the Orge River (nearby Paris). Total PFC levels were 73.0 +/- 3.0 ng L(-1) in water and 8.4 +/- 0.5 ng g(-1) in sediment. Th us cephalus) in the Orge River (nearby Paris). Total PFC levels were 73.0 +/- 3.0 ng L(-1) in water and 8.4 +/- 0.5 ng g(-1) in sediment. Th https://cdnsciencepub.com/doi/10.1139/a06-005 https://cdnsciencepub.com/doi/10.1139/a06-005 cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio cording to GHS or European CLP legislation. The aqueous bioconcentration factors for 6:2 FTSA were &lt;40 and the dietary assimilatio ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav ntration tests to compare the bioconcentration factors (BCFs) and physicochemical properties of each specific compound. Despite hav https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064268765&doi=10.1016%2fj.ecoenv.2019.04.022&partnerID= https://www.sciencedirect.com/science/article/pii/S0160412020319929 https://www.sciencedirect.com/science/article/pii/S0160412020319929 https://www.sciencedirect.com/science/article/pii/S0160412020319929 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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102884452&doi=10.1016%2fj.envpol.2021.116875&partnerID= range of geographical locations (e.g., South America, Russia, Antarctica) and habitats (e.g., high-mountain lakes, deep-ocean, and offsh range of geographical locations (e.g., South America, Russia, Antarctica) and habitats (e.g., high-mountain lakes, deep-ocean, and offsh range of geographical locations (e.g., South America, Russia, Antarctica) and habitats (e.g., high-mountain lakes, deep-ocean, and offsh range of geographical locations (e.g., South America, Russia, Antarctica) and habitats (e.g., high-mountain lakes, deep-ocean, and offsh https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 https://www.sciencedirect.com/science/article/pii/S2405665019300034 the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D the perfluorooctane sulfonate (PFOS) precursor perfluorooctane sulfonamide (PFOSA), were measured in livers of 68 beluga whales (D https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011716129&doi=10.1002%2fetc.3726&partnerID=40&md5=56 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043348811&doi=10.1016%2fj.chemosphere.2018.03.004&part https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043348811&doi=10.1016%2fj.chemosphere.2018.03.004&part https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043348811&doi=10.1016%2fj.chemosphere.2018.03.004&part https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105026248&doi=10.1016%2fj.jes.2021.03.036&partnerID=40& https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 https://doi.org/10.1021/acs.est.9b06773 or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra or PFBS following single equivalent intravenous or oral (rat only) doses. Serum clearance was more rapid for PFHxA than for PFBS. In ra s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both s rapid in rats as evidenced by a short time to maximum concentration (Cmax) of 30 min in male rats and 15 min in female rats at both c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum c acids (PFCAs) were quantifiable in feed, plasma, edible tissues, and urine. As percentages of unexcreted PFAA, the substances accum on of the elimination half-life of perfluorohexanoic acid (PFHxA) from the blood of humans. PFHxA biomonitoring data were obtained on of the elimination half-life of perfluorohexanoic acid (PFHxA) from the blood of humans. PFHxA biomonitoring data were obtained on of the elimination half-life of perfluorohexanoic acid (PFHxA) from the blood of humans. PFHxA biomonitoring data were obtained https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0045653519319927 https://www.sciencedirect.com/science/article/pii/S0048969720320519 https://www.sciencedirect.com/science/article/pii/S0048969720320519 https://www.sciencedirect.com/science/article/pii/S0048969720320519 use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture no use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture no use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture no use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture no use of long-chain perfluoroalkyl acids (PFAAs). To facilitate the environmental product stewardship assessment and premanufacture no https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112356450&doi=10.1021%2facs.est.1c00965&partnerID=40&m ether their occurrence would result in contamination of organisms in aquatic ecosystems, juvenile rainbow trout (Oncorhynchus mykis ether their occurrence would result in contamination of organisms in aquatic ecosystems, juvenile rainbow trout (Oncorhynchus mykis ether their occurrence would result in contamination of organisms in aquatic ecosystems, juvenile rainbow trout (Oncorhynchus mykis https://ec.europa.eu/environment/chemicals/reach/pdf/40424CRea010.i2 Task F Assessment of mobility as a criteria for P https://ec.europa.eu/environment/chemicals/reach/pdf/40424CRea010.i2 Task F Assessment of mobility as a criteria for P https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960391085&doi=10.1016%2fj.envres.2016.03.010&partnerID=4 https://doi.org/10.1021/es070895g https://doi.org/10.1021/es070895g https://doi.org/10.1021/es070895g https://doi.org/10.1021/es070895g https://doi.org/10.1021/es070895g access-date 11/24/2021 11/24/2021 11/24/2021 perfluorinated sulfonates (PFSAs) and their precursors perfluorinated sulfinates (PFSiAs), perfluorinated sulfonamides, and sulfonamido perfluorinated sulfonates (PFSAs) and their precursors perfluorinated sulfinates (PFSiAs), perfluorinated sulfonamides, and sulfonamido perfluorinated sulfonates (PFSAs) and their precursors perfluorinated sulfinates (PFSiAs), perfluorinated sulfonamides, and sulfonamido envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 envint.2019.105418&partnerID=40&md5=9da4ba2e9dc4f3667b2cd551143a6623 Ts) have been identified as important to the tissue distribution, species-specific accumulation, and species- and gender-specific elimina Ts) have been identified as important to the tissue distribution, species-specific accumulation, and species- and gender-specific elimina yrtph.2019.05.008&partnerID=40&md5=1624ff315ad5b53d531534709979bc90 yrtph.2019.05.008&partnerID=40&md5=1624ff315ad5b53d531534709979bc90 yrtph.2019.05.008&partnerID=40&md5=1624ff315ad5b53d531534709979bc90 yrtph.2019.05.008&partnerID=40&md5=1624ff315ad5b53d531534709979bc90 cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb cs.jafc.0c04485&partnerID=40&md5=7a2e4d785806a0385af72123519551bb gands are simulated to predict both bound conformation and interaction affinity, can be used to predict PFAS binding strength and bio gands are simulated to predict both bound conformation and interaction affinity, can be used to predict PFAS binding strength and bio 12/22/2021 12/22/2021 12/22/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 scitotenv.2020.144795&partnerID=40&md5=96982a7880234e70e2c68a7a3b918438 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.3623&partnerID=40&md5=5dc72fca4ee3b60d0732879502405c4a tc.2663&partnerID=40&md5=6b884262bdf826bbd48c12587ef9ce2a tc.2663&partnerID=40&md5=6b884262bdf826bbd48c12587ef9ce2a tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 tc.4640&partnerID=40&md5=38289efdc26b5ea4a3fe69fb3a567b90 s in organisms of aquatic food webs using a limited number of chemical, organism, and site-specific data inputs. The model is a modific s in organisms of aquatic food webs using a limited number of chemical, organism, and site-specific data inputs. The model is a modific 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 11/24/2021 12/10/2021 12/10/2021 12/10/2021 12/10/2021 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 tc.4869&partnerID=40&md5=0f2265e4cbe81469fe0188d95c9c9971 .4 +/- 0.5 ng g(-1) in sediment. They were in the range 43.1-4997.2 ng g(-1) in fish, in which PFC tissue distribution followed the order p .4 +/- 0.5 ng g(-1) in sediment. They were in the range 43.1-4997.2 ng g(-1) in fish, in which PFC tissue distribution followed the order p 10/1/2021 10/1/2021 &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a &lt;40 and the dietary assimilation efficiency, growth corrected half-life and dietary biomagnification factor (BMF) were 0.435, 23.1 d a h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff h specific compound. Despite having the same number of carbon atoms (C = 8), the BCFs of perfulorooctanoic acid (PFOA) and PFOS diff ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 ecoenv.2019.04.022&partnerID=40&md5=be5c64ef982987ee136d8018773a2027 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envres.2015.01.015&partnerID=40&md5=5ec843c16faaeebd308d59e6aa0bf57f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f envpol.2021.116875&partnerID=40&md5=4df791bba9faad5c6563972d9753ff2f ntain lakes, deep-ocean, and offshore waters) have been investigated in recent years enabling a better understanding of the global dist ntain lakes, deep-ocean, and offshore waters) have been investigated in recent years enabling a better understanding of the global dist ntain lakes, deep-ocean, and offshore waters) have been investigated in recent years enabling a better understanding of the global dist ntain lakes, deep-ocean, and offshore waters) have been investigated in recent years enabling a better understanding of the global dist 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 12/9/2021 ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas ed in livers of 68 beluga whales (Delphinapterus leucas) collected from two subpopulations, Cook Inlet and eastern Chukchi Sea, in Alas tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb tc.3726&partnerID=40&md5=56bceaa07e2dcce3b440610a902a09bb chemosphere.2018.03.004&partnerID=40&md5=742e2d1ef62080f0899d71a9ef29f978 chemosphere.2018.03.004&partnerID=40&md5=742e2d1ef62080f0899d71a9ef29f978 chemosphere.2018.03.004&partnerID=40&md5=742e2d1ef62080f0899d71a9ef29f978 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 jes.2021.03.036&partnerID=40&md5=c109c345187b80875938761629288f82 pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than pid for PFHxA than for PFBS. In rats, exposure to PFHxA and PFBS was up to 8-fold (intravenous) and 4-fold (oral) higher for males than and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- and 15 min in female rats at both the 2 and 100 mg/kg dose level. The plasma elimination half-life was somewhat longer in males (1.5- ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an ted PFAA, the substances accumulated in plasma (up to 51%), fat, and muscle tissues (collectively, meat 40-49%), liver (under 7%), an omonitoring data were obtained from a recently published study of professional ski wax technicians. These data were analyzed to pro omonitoring data were obtained from a recently published study of professional ski wax technicians. These data were analyzed to pro omonitoring data were obtained from a recently published study of professional ski wax technicians. These data were analyzed to pro sessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aqu sessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aqu sessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aqu sessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aqu sessment and premanufacture notification (PMN) process for a candidate replacement chemical, we conducted acute and chronic aqu cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 cs.est.1c00965&partnerID=40&md5=1cb9ef863d01a4e8e5d727fa0af3aeb4 nbow trout (Oncorhynchus mykiss) were separately exposed to a mixture of C6, C8, and C10 monoalkylated PFPAs and a mixture of C6 nbow trout (Oncorhynchus mykiss) were separately exposed to a mixture of C6, C8, and C10 monoalkylated PFPAs and a mixture of C6 nbow trout (Oncorhynchus mykiss) were separately exposed to a mixture of C6, C8, and C10 monoalkylated PFPAs and a mixture of C6 ment of mobility as a criteria for POPs_Final_up PFBS dated.pdf ment of mobility as a criteria for POPs_Final_up PFBS dated.pdf envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 envres.2016.03.010&partnerID=40&md5=fd14cca6c8ffc38b759c9fecbb8e1988 sulfonamides, and sulfonamido ethanols. Perfluorooctanesulfonate (PFOS) was the predominant compound in all measured seal tissu sulfonamides, and sulfonamido ethanols. Perfluorooctanesulfonate (PFOS) was the predominant compound in all measured seal tissu sulfonamides, and sulfonamido ethanols. Perfluorooctanesulfonate (PFOS) was the predominant compound in all measured seal tissu es- and gender-specific elimination rates of perfluoroalkyl carboxylates and perfluoroalkane sulfonates. Similar pharmacokinetics has b es- and gender-specific elimination rates of perfluoroalkyl carboxylates and perfluoroalkane sulfonates. Similar pharmacokinetics has b PFAS binding strength and biological half-life. We show that an easy-to-implement docking program, Autodock Vina, can successfully PFAS binding strength and biological half-life. We show that an easy-to-implement docking program, Autodock Vina, can successfully a inputs. The model is a modification of a previous model and incorporates new insights regarding the mechanism of bioaccumulation a inputs. The model is a modification of a previous model and incorporates new insights regarding the mechanism of bioaccumulation istribution followed the order plasma > liver > gills > gonads > muscle. Sediment-water distribution coefficients (logK(d)) and bioaccum istribution followed the order plasma > liver > gills > gonads > muscle. Sediment-water distribution coefficients (logK(d)) and bioaccum ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C ctor (BMF) were 0.435, 23.1 d and 0.295, respectively. These data indicate that 6:2 FTSA is not bioaccumulative in aquatic organisms. C anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi anoic acid (PFOA) and PFOS differed by more than two orders of magnitude (PFOA BCF = < 5.1 to 9.4; PFOS BCF = 720 to 1300). The hi understanding of the global distribution of PFCs in aquatic organisms. High concentrations of PFCs continue to be detected in invertebr understanding of the global distribution of PFCs in aquatic organisms. High concentrations of PFCs continue to be detected in invertebr understanding of the global distribution of PFCs in aquatic organisms. High concentrations of PFCs continue to be detected in invertebr understanding of the global distribution of PFCs in aquatic organisms. High concentrations of PFCs continue to be detected in invertebr nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga nd eastern Chukchi Sea, in Alaska between 1989 and 2006. PFOS and PFOSA were the dominant compounds measured in both beluga old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther old (oral) higher for males than females and serum clearance of PFHxA and PFBS was more rapid in females than males; however, ther somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c somewhat longer in males (1.5-1.7 h) than in females (0.5-0.7 h). Absorption in the mouse was also rapid with the maximum plasma c t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo t 40-49%), liver (under 7%), and kidney (under 2%) for most substances. An exception was perfluorooctanesulfonic acid (PFOS), with lo hese data were analyzed to provide estimates of the apparent half-life of PFHxA from humans, and comparisons were made with kineti hese data were analyzed to provide estimates of the apparent half-life of PFHxA from humans, and comparisons were made with kineti hese data were analyzed to provide estimates of the apparent half-life of PFHxA from humans, and comparisons were made with kineti nducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-pro nducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-pro nducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-pro nducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-pro nducted acute and chronic aquatic toxicity tests to evaluate the toxicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-pro ated PFPAs and a mixture of C6/C6, C6/C8, and C8/C8 dialkylated PFPiAs in the diet for 31 days, followed by 32 days of depuration. Tis ated PFPAs and a mixture of C6/C6, C6/C8, and C8/C8 dialkylated PFPiAs in the diet for 31 days, followed by 32 days of depuration. Tis ated PFPAs and a mixture of C6/C6, C6/C8, and C8/C8 dialkylated PFPiAs in the diet for 31 days, followed by 32 days of depuration. Tis d in all measured seal tissues (up to 1665 ng g(-1) wet weight in liver tissue). The dominant PFCAs were perfluorononanoic acid (PFNA) d in all measured seal tissues (up to 1665 ng g(-1) wet weight in liver tissue). The dominant PFCAs were perfluorononanoic acid (PFNA) d in all measured seal tissues (up to 1665 ng g(-1) wet weight in liver tissue). The dominant PFCAs were perfluorononanoic acid (PFNA) lar pharmacokinetics has been identified in fish. Yet, no mechanistic model exists for the bioaccumulation of PFAAs in fish that explicit lar pharmacokinetics has been identified in fish. Yet, no mechanistic model exists for the bioaccumulation of PFAAs in fish that explicit ock Vina, can successfully redock perfluorooctanesulfonate (PFOS) to human serum albumin with deviations smaller than 2 A. Further ock Vina, can successfully redock perfluorooctanesulfonate (PFOS) to human serum albumin with deviations smaller than 2 A. Further anism of bioaccumulation derived from laboratory experiments and field studies as well as improvements in model parameterization. anism of bioaccumulation derived from laboratory experiments and field studies as well as improvements in model parameterization. nts (logK(d)) and bioaccumulation factors (logBAF) were in the range 0.8-4.3 and 0.9-6.7, respectively. Both distribution coefficients po nts (logK(d)) and bioaccumulation factors (logBAF) were in the range 0.8-4.3 and 0.9-6.7, respectively. Both distribution coefficients po tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk tive in aquatic organisms. Comparison of PNECs with the reported surface water concentrations (non-spill situations) suggests low risk BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan BCF = 720 to 1300). The highest BCFs were obtained from perfluorododecanoic acid (BCF = 10,000 to 16,000) and perfluorotetradecan o be detected in invertebrates, fish, reptiles, and marine mammals worldwide. Perfluorooctane sulfonate (PFOS) is still the predomina o be detected in invertebrates, fish, reptiles, and marine mammals worldwide. Perfluorooctane sulfonate (PFOS) is still the predomina o be detected in invertebrates, fish, reptiles, and marine mammals worldwide. Perfluorooctane sulfonate (PFOS) is still the predomina o be detected in invertebrates, fish, reptiles, and marine mammals worldwide. Perfluorooctane sulfonate (PFOS) is still the predomina s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain s measured in both beluga stock populations, with overall median concentrations of 10.8 ng/g and 22.8 ng/g, respectively. Long-chain than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders than males; however, there was no appreciable difference in the extent or rate of urinary elimination between compounds or genders th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab th the maximum plasma concentration occurring between 15 and 30 min after dosing. The maximum concentration was not appreciab ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ulfonic acid (PFOS), with lower affinity for plasma (23%) and higher for liver (35%). A toxicokinetic model is developed to quantify the a ons were made with kinetic studies of PFHxA elimination from mice, rats and monkeys. The apparent elimination half-life of PFHxA in ons were made with kinetic studies of PFHxA elimination from mice, rats and monkeys. The apparent elimination half-life of PFHxA in ons were made with kinetic studies of PFHxA elimination from mice, rats and monkeys. The apparent elimination half-life of PFHxA in (heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green al (heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green al (heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green al (heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green al (heptafluoropropoxy)-propanoate (C6HF11O3.H3N) or the acid form of the substance to the cladoceran, Daphnia magna, the green al 32 days of depuration. Tissue distribution indicated preferential partitioning to blood and liver. Depuration half-lives ranged from 3 to 32 days of depuration. Tissue distribution indicated preferential partitioning to blood and liver. Depuration half-lives ranged from 3 to 32 days of depuration. Tissue distribution indicated preferential partitioning to blood and liver. Depuration half-lives ranged from 3 to uorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA), but their concentrations were much lower compared to PFOS. The mean uorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA), but their concentrations were much lower compared to PFOS. The mean uorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA), but their concentrations were much lower compared to PFOS. The mean PFAAs in fish that explicitly considers protein interactions. In this work, we present the first mechanistic protein-binding bioconcentra PFAAs in fish that explicitly considers protein interactions. In this work, we present the first mechanistic protein-binding bioconcentra smaller than 2 A. Furthermore, predicted binding strengths largely fall within one standard deviation of measured values for perfluori smaller than 2 A. Furthermore, predicted binding strengths largely fall within one standard deviation of measured values for perfluori model parameterization. The new elements of the model include: A model for the partitioning of chemicals into organisms; kinetic mo model parameterization. The new elements of the model include: A model for the partitioning of chemicals into organisms; kinetic mo distribution coefficients positively correlated with perfluoroalkyl chain length. Field-based biota-sediment accumulation factors (BSAFs distribution coefficients positively correlated with perfluoroalkyl chain length. Field-based biota-sediment accumulation factors (BSAFs uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com uations) suggests low risk to aquatic organisms from 6:2 FTSA. Future studies are needed to elucidate the biotic and abiotic fate of com ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi ) and perfluorotetradecanoic acid (BCF = 16,000 to 17,000). The longest observed depuration half-lives were for perfluorohexadecanoi FOS) is still the predominant PFC detected (mean concentrations up to 1900 ng/g ww) in addition to important concentrations of long FOS) is still the predominant PFC detected (mean concentrations up to 1900 ng/g ww) in addition to important concentrations of long FOS) is still the predominant PFC detected (mean concentrations up to 1900 ng/g ww) in addition to important concentrations of long FOS) is still the predominant PFC detected (mean concentrations up to 1900 ng/g ww) in addition to important concentrations of long , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou , respectively. Long-chain perfluorocarboxylates, PFCAs (9 to 14 carbons), were detected in more than 80% of the samples. Perfluorou en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of en compounds or genders. There were no apparent differences between genders in the serum half-life for PFHxA following 26 days of ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The ntration was not appreciably different between male and female mice (8 g equiv./g at 2 mg/kg; 350 g equiv./g at 100 mg/kg). The developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac developed to quantify the absorption, distribution, and excretion of PFAAs and to calculate elimination half-lives. Perfluorohexanoic ac ation half-life of PFHxA in highly exposed humans ranged between 14 and 49d with a geomean of 32d. The half-lives of PFHxA in mice, ation half-life of PFHxA in highly exposed humans ranged between 14 and 49d with a geomean of 32d. The half-lives of PFHxA in mice, ation half-life of PFHxA in highly exposed humans ranged between 14 and 49d with a geomean of 32d. The half-lives of PFHxA in mice, phnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, On phnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, On phnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, On phnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, On phnia magna, the green alga, Pseudokirchneriella subcapitata, and a number of freshwater fish species including the rainbow trout, On half-lives ranged from 3 to 43 days and increased with the number of perfluorinated carbons present in the chemical. The assimilation half-lives ranged from 3 to 43 days and increased with the number of perfluorinated carbons present in the chemical. The assimilation half-lives ranged from 3 to 43 days and increased with the number of perfluorinated carbons present in the chemical. The assimilation mpared to PFOS. The mean whole body burden in harbor seals of all detected PFCs was estimated to be 2665+/-1207 microg absolute. mpared to PFOS. The mean whole body burden in harbor seals of all detected PFCs was estimated to be 2665+/-1207 microg absolute. mpared to PFOS. The mean whole body burden in harbor seals of all detected PFCs was estimated to be 2665+/-1207 microg absolute. otein-binding bioconcentration model for PFAAs in fish. Our model considers PFAA uptake via passive diffusion at the gills, association w otein-binding bioconcentration model for PFAAs in fish. Our model considers PFAA uptake via passive diffusion at the gills, association w asured values for perfluorinated alkyl acids (PFAAs). Correlations with half-lives suggest both membrane partitioning and protein inter asured values for perfluorinated alkyl acids (PFAAs). Correlations with half-lives suggest both membrane partitioning and protein inter into organisms; kinetic models for predicting chemical concentrations in algae, phytoplankton, and zooplankton; new allometric relati into organisms; kinetic models for predicting chemical concentrations in algae, phytoplankton, and zooplankton; new allometric relati cumulation factors (BSAFs) are also reported, for the first time for PFCs other than perfluorooctane sulfonate. logBSAF ranged between cumulation factors (BSAFs) are also reported, for the first time for PFCs other than perfluorooctane sulfonate. logBSAF ranged between otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. otic and abiotic fate of commercial AFFF surfactants in the environment. for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo for perfluorohexadecanoic acid (48 to 54 days) and PFOS (45 to 52 days). The concentrations of PFCs were highest in the viscera, follo ant concentrations of long-chain perfluoroalkyl carboxylates (PFCAs; sum PFCAs up to 400 ng/g ww). More studies have evaluated the ant concentrations of long-chain perfluoroalkyl carboxylates (PFCAs; sum PFCAs up to 400 ng/g ww). More studies have evaluated the ant concentrations of long-chain perfluoroalkyl carboxylates (PFCAs; sum PFCAs up to 400 ng/g ww). More studies have evaluated the ant concentrations of long-chain perfluoroalkyl carboxylates (PFCAs; sum PFCAs up to 400 ng/g ww). More studies have evaluated the of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me of the samples. Perfluoroundecanoic acid (PFUnA) and perfluorotridecanoic acid (PFTriA) made up a large percentage of the PFCAs me FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. FHxA following 26 days of repeated oral dosing in rats; exposure decreased upon repeated dosing. quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor quiv./g at 100 mg/kg). The primary route of elimination was via the urine. PFHx was not metabolized in rat or mouse hepatocytes, nor ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 ves. Perfluorohexanoic acid (PFHxA), a PFCA, had the shortest half-life at 4.1 days. PFSAs are eliminated more slowly (e.g., half-life of 6 half-lives of PFHxA in mice, rats, monkeys and humans were proportional to body weight with no differences observed between gende half-lives of PFHxA in mice, rats, monkeys and humans were proportional to body weight with no differences observed between gende half-lives of PFHxA in mice, rats, monkeys and humans were proportional to body weight with no differences observed between gende ding the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determin ding the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determin ding the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determin ding the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determin ding the rainbow trout, Oncorhynchus mykiss, In addition, testing with the common carp, Cyprinus carpio, was conducted to determin chemical. The assimilation efficiencies (alpha, 7-34%) and biomagnification factors (BMFs, 0.007-0.189) calculated here for PFPAs and P chemical. The assimilation efficiencies (alpha, 7-34%) and biomagnification factors (BMFs, 0.007-0.189) calculated here for PFPAs and P chemical. The assimilation efficiencies (alpha, 7-34%) and biomagnification factors (BMFs, 0.007-0.189) calculated here for PFPAs and P 5+/-1207 microg absolute. The major amount of the total PFCs burden in the bodies was in blood (38%) and liver (36%), followed by m 5+/-1207 microg absolute. The major amount of the total PFCs burden in the bodies was in blood (38%) and liver (36%), followed by m 5+/-1207 microg absolute. The major amount of the total PFCs burden in the bodies was in blood (38%) and liver (36%), followed by m on at the gills, association with serum albumin in the circulatory and extracellular spaces, association with FABP in the liver, and renal e on at the gills, association with serum albumin in the circulatory and extracellular spaces, association with FABP in the liver, and renal e titioning and protein interactions are important, and that serum albumin is only one of a number of proteins controlling the fate of the titioning and protein interactions are important, and that serum albumin is only one of a number of proteins controlling the fate of the kton; new allometric relationships for predicting gill ventilation rates in a wide range of aquatic species; and a mechanistic model for p kton; new allometric relationships for predicting gill ventilation rates in a wide range of aquatic species; and a mechanistic model for p e. logBSAF ranged between -1.3 and 1.5 and was negatively correlated with the perfluoroalkyl chain length in the case of carboxylic aci e. logBSAF ranged between -1.3 and 1.5 and was negatively correlated with the perfluoroalkyl chain length in the case of carboxylic aci highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w highest in the viscera, followed by the head, integument, and remaining parts of the test fish. PFCs concentrations in the integument, w udies have evaluated the bioaccumulation and biomagnification of these compounds in both freshwater and marine food webs. Sever udies have evaluated the bioaccumulation and biomagnification of these compounds in both freshwater and marine food webs. Sever udies have evaluated the bioaccumulation and biomagnification of these compounds in both freshwater and marine food webs. Sever udies have evaluated the bioaccumulation and biomagnification of these compounds in both freshwater and marine food webs. Sever rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati rcentage of the PFCAs measured with median concentrations of 8.49 ng/g and 4.38 ng/g, respectively. To compare differences in locati r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e r mouse hepatocytes, nor were any metabolites observed after oral dosing in either rodent species. Essentially 100% of the dose was e re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the re slowly (e.g., half-life of 634 days for PFOS). PFAAs in pigs exhibit longer elimination half-lives than in most organisms reported in the observed between genders, indicating similar volumes of distribution and similar elimination mechanisms among mammalian species observed between genders, indicating similar volumes of distribution and similar elimination mechanisms among mammalian species observed between genders, indicating similar volumes of distribution and similar elimination mechanisms among mammalian species was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current was conducted to determine the bioconcentration potential of the acid form of the compound. Based on the relevant criteria in current lated here for PFPAs and PFPiAs were lower than those previously observed for the perfluorocarboxylates (PFCAs) and perfluorosulfon lated here for PFPAs and PFPiAs were lower than those previously observed for the perfluorocarboxylates (PFCAs) and perfluorosulfon lated here for PFPAs and PFPiAs were lower than those previously observed for the perfluorocarboxylates (PFCAs) and perfluorosulfon liver (36%), followed by muscle (13%), lung (8%), kidney (2%), blubber (2%), heart (1%), brain (1%), thymus (<0.01%) and thyroid (<0.01 liver (36%), followed by muscle (13%), lung (8%), kidney (2%), blubber (2%), heart (1%), brain (1%), thymus (<0.01%) and thyroid (<0.01 liver (36%), followed by muscle (13%), lung (8%), kidney (2%), blubber (2%), heart (1%), brain (1%), thymus (<0.01%) and thyroid (<0.01 BP in the liver, and renal elimination and reabsorption facilitated by OAT proteins. The model is evaluated using measured bioconcent BP in the liver, and renal elimination and reabsorption facilitated by OAT proteins. The model is evaluated using measured bioconcent controlling the fate of these chemicals in organisms. However, few data are available for validation of our approach as a broad screen controlling the fate of these chemicals in organisms. However, few data are available for validation of our approach as a broad screen a mechanistic model for predicting gastrointestinal magnification of organic chemicals in a range of species. Model performance is eva a mechanistic model for predicting gastrointestinal magnification of organic chemicals in a range of species. Model performance is eva n the case of carboxylic acids. n the case of carboxylic acids. ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs ations in the integument, which was in direct contact with the test substances, were relatively greater than that of other lipophilic subs d marine food webs. Several reports have indicated a decrease in PFOS levels over time in contrast to PFCA concentrations that have t d marine food webs. Several reports have indicated a decrease in PFOS levels over time in contrast to PFCA concentrations that have t d marine food webs. Several reports have indicated a decrease in PFOS levels over time in contrast to PFCA concentrations that have t d marine food webs. Several reports have indicated a decrease in PFOS levels over time in contrast to PFCA concentrations that have t mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con mpare differences in location, year, sex, and length, backward stepwise multiple regression models of the individual and total PFC con lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 lly 100% of the dose was eliminated in urine within 24 h demonstrating that PFHx is readily absorbed and bioavailability approaches 1 organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. organisms reported in the literature, but still shorter than in humans. mong mammalian species. Compared to long-chain perfluoroalkyl acid analogs, PFHxA is rapidly cleared from biota. The consistent we mong mammalian species. Compared to long-chain perfluoroalkyl acid analogs, PFHxA is rapidly cleared from biota. The consistent we mong mammalian species. Compared to long-chain perfluoroalkyl acid analogs, PFHxA is rapidly cleared from biota. The consistent we relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substan relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substan relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substan relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substan relevant criteria in current regulatory frameworks, the results of the aquatic toxicity and bioconcentration studies indicate the substan PFCAs) and perfluorosulfonates (PFSAs) in the same test organism. Bioaccumulation was observed to decreased in the order of PFSAs > PFCAs) and perfluorosulfonates (PFSAs) in the same test organism. Bioaccumulation was observed to decreased in the order of PFSAs > PFCAs) and perfluorosulfonates (PFSAs) in the same test organism. Bioaccumulation was observed to decreased in the order of PFSAs > <0.01%) and thyroid (<0.01%). These data suggest large differences in body burden and accumulation pattern of PFCs in marine mamm <0.01%) and thyroid (<0.01%). These data suggest large differences in body burden and accumulation pattern of PFCs in marine mamm <0.01%) and thyroid (<0.01%). These data suggest large differences in body burden and accumulation pattern of PFCs in marine mamm sing measured bioconcentration and tissue distribution data collected in two previous studies of rainbow trout (Oncorhynchus mykiss) sing measured bioconcentration and tissue distribution data collected in two previous studies of rainbow trout (Oncorhynchus mykiss) pproach as a broad screening tool, and available data are highly variable. We therefore call for collection of new data, particularly incl pproach as a broad screening tool, and available data are highly variable. We therefore call for collection of new data, particularly incl Model performance is evaluated using empirical data from three different freshwater ecosystems involving 1,019 observations for 35 Model performance is evaluated using empirical data from three different freshwater ecosystems involving 1,019 observations for 35 hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi hat of other lipophilic substance (hexachlorobenzene). It is likely that Clog P would be a better parameter than log K (ow) for the predi concentrations that have tended to increase in tissues of aquatic organisms at many locations. The detection of precursor metabolites concentrations that have tended to increase in tissues of aquatic organisms at many locations. The detection of precursor metabolites concentrations that have tended to increase in tissues of aquatic organisms at many locations. The detection of precursor metabolites concentrations that have tended to increase in tissues of aquatic organisms at many locations. The detection of precursor metabolites dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS dividual and total PFC concentrations were used. Spatially, the Cook Inlet belugas had higher concentrations of most PFCAs and PFOS oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days oavailability approaches 100%, even at a dose as high as 100 mg/kg. The route and extent of elimination was unchanged after 14 days m biota. The consistent weight-normalized elimination half-lives for PFHxA in mammalian species indicates that results obtained from m biota. The consistent weight-normalized elimination half-lives for PFHxA in mammalian species indicates that results obtained from m biota. The consistent weight-normalized elimination half-lives for PFHxA in mammalian species indicates that results obtained from tudies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environme tudies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environme tudies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environme tudies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environme tudies indicate the substance is of low concern for aquatic hazard and bioconcentration in aquatic organisms. Evaluation of environme sed in the order of PFSAs > PFCAs > PFPAs of equal perfluorocarbon chain length and was dependent on the charge of the polar headg sed in the order of PFSAs > PFCAs > PFPAs of equal perfluorocarbon chain length and was dependent on the charge of the polar headg sed in the order of PFSAs > PFCAs > PFPAs of equal perfluorocarbon chain length and was dependent on the charge of the polar headg n of PFCs in marine mammals. n of PFCs in marine mammals. n of PFCs in marine mammals. out (Oncorhynchus mykiss) and common carp (Cyprinus carpio). Comparing our model with previous attempts to describe PFAA biocon out (Oncorhynchus mykiss) and common carp (Cyprinus carpio). Comparing our model with previous attempts to describe PFAA biocon new data, particularly including proteins other than serum albumin and substances beyond perfluorooctanoic acid (PFOA) and PFOS. T new data, particularly including proteins other than serum albumin and substances beyond perfluorooctanoic acid (PFOA) and PFOS. T 1,019 observations for 35 species and 64 chemicals. The effects of each modification on the model's performance are illustrated. The n 1,019 observations for 35 species and 64 chemicals. The effects of each modification on the model's performance are illustrated. The n an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim an log K (ow) for the prediction of BCFs for PFCs. Threshold values for PFCs bioaccumulation potential (molecular weight = 700, maxim of precursor metabolites and isomers has become more frequently reported in environmental assessments yielding important inform of precursor metabolites and isomers has become more frequently reported in environmental assessments yielding important inform of precursor metabolites and isomers has become more frequently reported in environmental assessments yielding important inform of precursor metabolites and isomers has become more frequently reported in environmental assessments yielding important inform s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s of most PFCAs and PFOS (p < 0.05); however, these belugas had a lower median concentration of PFOSA when compared to belugas f s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte s unchanged after 14 days of daily dosing. Tissues were collected at three time points (rat: 0.5, 2, and 24 h; mice: 0.25, 1, and 24 h) afte hat results obtained from animal models are suitable for establishment of PFHxA benchmark dose and reference dose hazard endpoin hat results obtained from animal models are suitable for establishment of PFHxA benchmark dose and reference dose hazard endpoin hat results obtained from animal models are suitable for establishment of PFHxA benchmark dose and reference dose hazard endpoin s. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the availabl s. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the availabl s. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the availabl s. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the availabl s. Evaluation of environmental monitoring data in conjunction with the predicted no effect concentration (PNEC) based on the availabl charge of the polar headgroup. Bioaccumulation of the PFPiAs was observed to be low due to their rapid elimination via metabolism t charge of the polar headgroup. Bioaccumulation of the PFPiAs was observed to be low due to their rapid elimination via metabolism t charge of the polar headgroup. Bioaccumulation of the PFPiAs was observed to be low due to their rapid elimination via metabolism t ts to describe PFAA bioconcentration using a nonspecific (partitioning-type) approach shows that inclusion of protein interactions is ke ts to describe PFAA bioconcentration using a nonspecific (partitioning-type) approach shows that inclusion of protein interactions is ke ic acid (PFOA) and PFOS. The methods we discuss in this work can serve as a framework for guiding such data collection. ic acid (PFOA) and PFOS. The methods we discuss in this work can serve as a framework for guiding such data collection. mance are illustrated. The new model is able to provide better estimates of bioaccumulation factors in comparison to the previous food mance are illustrated. The new model is able to provide better estimates of bioaccumulation factors in comparison to the previous food cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff cular weight = 700, maximum diameter = 2 nm) seemed to deviate from those generally reported because of the specific steric bulk eff yielding important information on the sources and distribution of these contaminants. The integration of environmental/ecological ch yielding important information on the sources and distribution of these contaminants. The integration of environmental/ecological ch yielding important information on the sources and distribution of these contaminants. The integration of environmental/ecological ch yielding important information on the sources and distribution of these contaminants. The integration of environmental/ecological ch hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co hen compared to belugas from the eastern Chukchi Sea (p < 0.05). Temporal trends indicated most PFCAs, PFHxS, PFOS, and PFOSA co mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all mice: 0.25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all ence dose hazard endpoints for use in human risk assessments. ence dose hazard endpoints for use in human risk assessments. ence dose hazard endpoints for use in human risk assessments. NEC) based on the available data suggest low risk to aquatic organisms. NEC) based on the available data suggest low risk to aquatic organisms. NEC) based on the available data suggest low risk to aquatic organisms. NEC) based on the available data suggest low risk to aquatic organisms. NEC) based on the available data suggest low risk to aquatic organisms. mination via metabolism to the corresponding PFPAs. Here, we report the first observation of an in vivo cleavage of the carbon-phosph mination via metabolism to the corresponding PFPAs. Here, we report the first observation of an in vivo cleavage of the carbon-phosph mination via metabolism to the corresponding PFPAs. Here, we report the first observation of an in vivo cleavage of the carbon-phosph f protein interactions is key to accurately predicting tissue-specific PFAA distribution and bioconcentration. f protein interactions is key to accurately predicting tissue-specific PFAA distribution and bioconcentration. arison to the previous food web bioaccumulation model while the model input requirements remain largely unchanged. arison to the previous food web bioaccumulation model while the model input requirements remain largely unchanged. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. f the specific steric bulk effect of molecule size. nvironmental/ecological characteristics (e.g., latitude/longitude, salinity, and/or trophic status at sampling locations) and biological var nvironmental/ecological characteristics (e.g., latitude/longitude, salinity, and/or trophic status at sampling locations) and biological var nvironmental/ecological characteristics (e.g., latitude/longitude, salinity, and/or trophic status at sampling locations) and biological var nvironmental/ecological characteristics (e.g., latitude/longitude, salinity, and/or trophic status at sampling locations) and biological var FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA FHxS, PFOS, and PFOSA concentrations increased from 1989 to 2006 (p < 0.05). Males had significantly higher concentrations of PFTriA e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. e at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species. vage of the carbon-phosphorus bond in fish, as well as, the first in vivo biotransformation of a perfluoroalkyl acid (PFAA). As was previo vage of the carbon-phosphorus bond in fish, as well as, the first in vivo biotransformation of a perfluoroalkyl acid (PFAA). As was previo vage of the carbon-phosphorus bond in fish, as well as, the first in vivo biotransformation of a perfluoroalkyl acid (PFAA). As was previo cations) and biological variables (e.g., age, gender, life cycle, migration, diet composition, growth rate, food chain length, metabolism, cations) and biological variables (e.g., age, gender, life cycle, migration, diet composition, growth rate, food chain length, metabolism, cations) and biological variables (e.g., age, gender, life cycle, migration, diet composition, growth rate, food chain length, metabolism, cations) and biological variables (e.g., age, gender, life cycle, migration, diet composition, growth rate, food chain length, metabolism, r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c r concentrations of PFTriA, SigmaPFCA, and PFOS (p < 0.05). Perfluorononanic acid (PFNA) and PFOS showed a significant decrease in c acid (PFAA). As was previously observed for PFCAs and PFSAs, none of the BMFs determined here for the PFPAs and PFPiAs were grea acid (PFAA). As was previously observed for PFCAs and PFSAs, none of the BMFs determined here for the PFPAs and PFPiAs were grea acid (PFAA). As was previously observed for PFCAs and PFSAs, none of the BMFs determined here for the PFPAs and PFPiAs were grea chain length, metabolism, and elimination) are essential elements in order to adequately study the environmental fate and distributio chain length, metabolism, and elimination) are essential elements in order to adequately study the environmental fate and distributio chain length, metabolism, and elimination) are essential elements in order to adequately study the environmental fate and distributio chain length, metabolism, and elimination) are essential elements in order to adequately study the environmental fate and distributio d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs d a significant decrease in concentration with increasing animal length (p < 0.05). These observations suggest the accumulation of PFCs FPAs and PFPiAs were greater than one, which suggests PFAAs do not biomagnify from dietary exposure in juvenile rainbow trout. FPAs and PFPiAs were greater than one, which suggests PFAAs do not biomagnify from dietary exposure in juvenile rainbow trout. FPAs and PFPiAs were greater than one, which suggests PFAAs do not biomagnify from dietary exposure in juvenile rainbow trout. mental fate and distribution of PFCs and should be more frequently considered in study design. mental fate and distribution of PFCs and should be more frequently considered in study design. mental fate and distribution of PFCs and should be more frequently considered in study design. mental fate and distribution of PFCs and should be more frequently considered in study design. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. t the accumulation of PFCs in belugas is influenced by year, location, sex, and length. uvenile rainbow trout. uvenile rainbow trout. uvenile rainbow trout.