Document x5dqjMmb9NDVn5nZyrZB1v2r1

CONFIDENTIAL World Register of Cases of ANGIOSARCOMA OF THE LIVER (ASL) due to VCM REVIEW DATE 1st JANUARY 1990 ********* Collated by: Or Brian Bannatt Occupational Health ICI Chemicals and Pi Hillhousa Site PO Box 4 Thornton-Cla velays Blackpool FY3 400 England wars Ltd (Telephone (Telex (Fax 0253 861632 J 67483 ICIPLH6) 0253 B61861 J C0j:,7J-7>T "TIATi SuViest"-.) r.-; Ross v. '-o....... i4th >" -; " ' Calcasieu r " V? 1 CMA 010700 LIVER ANGIOSARCOMA CASES CIRCULATION OF REGISTER CONFIDENTIAL FEBRUARY 1990 8AGSHAW DrIHM BAND Dr P R BARRAT Dr G BAXTER Dr P BAYLAC Dr BELLEC Dr BENECH Dr M BENNETT Dr B BERTAZZI Dr P BERTUZZI M BEYNON D W S BISHOP Dr C BORRELLI F E BRAUN Dr C L J BROGDEN M E BROWN Or M G BYREN Dr David CAMPION Dr Catherine CARTER Dr J T CATANZARITI A CELLA C CHANCE M CLARKE Dr E A CLAYTON H CONTASSOT Dr J C DAVIES J G DELORME Dr F DEPLAN Dr F DIETZ Dr H W DOLL Prof Sir Richard DOMBROWSKI S L S DOORNBOS Dr N DRUMWRIGHT Dr J R DUPONT G EMMINGER H ERNST Dr W EVANS Dr A E J FALK Dr H FARMERY Dr K FAVRE Dr FIELDING Miss C Hydro Polymers Ltd, Newton Aycliffe, UK Cancer Control Agency of British Columbia, Vacouver, Canada AECRP, Commentry, France University of Cambridge UK Atochem, Chauny, France Rhone Poulenc, Aubervillers, France Naphtachimie, Lavera, France ICI Hillhouse, UK Inst of Occupational Health, Milan University, Italy EVC, Brussels, Belgium ICI Runcorn, UK EMAS, Cardiff, UK Georgia Gulf, Delaware City, USA Akzo, Arnhem, The Netherlands ICI Runcorn, UK Shell, An Den Haag, The Netherlands Nobel Industrier, Sundsvall, Sweden Health & Safety Executive, Bootle, UK EMAS, London, UK EVC, Brussels, Belgium EVC, Brussels, Belgium ICI Runcorn, UK Ontario Cancer Foundation, Toronto, Canada Norsk Hydro, Newton Aycliffe, UK Atochem, Saint-Fons, France EVC, Brussels, Belgium Quebec, Canada Atochem, Jarrie, France B F Goodrich, Akron, Ohio, USA Imperial Cancer Research Fund, Oxford University, UK Dow Chemical, Midland, Michigan, USA DSM, Beek, The Netherlands Vista Chemical, Houston, Texas, USA APME, Brussels, Belgium VKE, Frankfurt, Germany Berufsgenossenschaft der Chemischen Industries, Nurnberg, Germany Lever Bros, Warrington, UK Centers for Disease Control, Atlanta, Georgia, USA ICI Hillhouse, UK Atochem, Montluel, France ICI Millbank, London, UK CMA 010701 coifideitial Stihjtct to Protective Order in Conoco, Inc.. No. 90-4837 14th Judicial District Court 6ftl09*ttu Parish, Louisiana FILLINGER J FINCHAM Ms Shirley FOA Prof V FORMAN Dr D FRASE R W FREIESLEBEN Dr W FRIEDEL Dr H P GAFFEY Dr W GIUDICE Dr S GOTTESMAN Dr R T GROISMAN D HILLMAN Dr D W HOWARD Dr J K HOWE Dr W HUMPHRY Dr N F JOHNSON Dr C A JOHNSON Roy N KAIPERT Dr J H KAUNAS Dr J KLEIN Dr H LAGAST Dr H LANHAM Dr John LANOUZIERE Dr Claudine LAWRENCE-JONES Sir C LEE Dr F I LEESER Dr Jenny LELBACH Prof Dr WK LEVEQUE Dr G LEVISON Prof Dr D A LEWIS Dr P LIGO Dr R N LO MARTIRE Prof N LUSS R D LUSSATO Dr Josette MALTONI Prof C MATTIUSSI Dr R MELTON 3 MIDDLETON D MOKKA Mr MONTESANO Dr R MOTTI Dr A A MUNOZ MOUTON Dr M MacSWEEN Prof RNM NAKAMURA Dr S OSMAN Dr J PADDLE Dr G M 2 Solvay, Brussels, Belgium Alberta Cancer Board, Edmonton, Canada Inst Industrial Medicine, Milan, Italy Imperial Cancer Research Fund, Oxford University, UK DiversiTech General, Akron, Ohio, USA ECVM, Brussels, Belgium Berufsgenossenschaft der Chemischen Industries, Heidelberg, Germany Monsanto Co, St Louis, Missouri, USA Montedipe, Venice, Italy The Vinyl Institute, Wayne, NJ, USA Electrochemical Industries, Acre, Israel Diamond Shamrock Corp, Dallas, Texas, USA University of Otago School of Medicine, Wellington, New Zealand ICI Runcorn, UK ICI Australia, Melbourne, Australia Goodyear Tire and Rubber, Akron, Ohio, USA GenCorp, Fairlawn, Ohio, USA Dow Chemical Europe, Horgen, Switzerland Imperial Oil, Sarnia, Ontario, Canada Dynamit Nobel, Troisdorf, Germany Solvay, Brussels, Belgium Dow Chemical, Midland, Michigan, USA Solvay, Tavaux, France Chief Medical Officer, ICI, London, UK Victoria Hospital, Blackpool, Lancs, UK ICI Runcorn, UK University of Bonn, West Germany CDF Chimie, AZF, Bully-les-Mines, France Guy's Hospital, London, UK Chemical Industries Association, London, UK Dupont, Wilmington, Delaware, USA EniChem, Milan, Italy Occidental Chemical, Pottstown, Pennsylvania, USA Atochem, Port de Bouc, France Institute di Oncologia, Bologna, Italy Montedison, Milan, Italy Formosa Plastics, Delaware City, USA Hydro Polymers Ltd, Newton Aycliffe, UK Neste Oy, Espoo, Finland IARC, Lyon, France ICI Duperial, Buenos Aires, Argentina Rio Rodano, Madrid, Spain Western Infirmary, Glasgow, Scotland Japanese PVC Association, Tokyo, Japan Health & Safety Executive, Bootle, UK ICI Central Medical Group, Alderley Park, UK CMA 010702 !--- coitipbetiat. Protective Order &rrZm -^Sg,Q. Inc-, No. so\\ ctli/flclal Dlstrict Coui " 'Calcasiau Parish, Louisian; PAQUET Dr Christiane PATERSON Dr J C PIRASTU Dr Roberta POSSBERG Dr J PUECH Dr A M PURDHAM Dr J RAMBAUD Dr J RICHARD Dr A ROBSON Mrs D ROSA Dr HS RUTY Dr J SALG Dr Joyce A SCHIPPER Dr H SCHUCKMANN Dr F SERONNE Dr D SHAH Dr Has SIGRIST Dr J SMITH Prof Allan H SMITH Dr P M SPIRTAS Dr R STAFFORD Dr J STAHNECKER Dr E SULAIMAN Dr TACHECI Dr H TAMBURRO Prof CH TENKHOFF Dr N TEPPER Dr L B TERWIESCH Dr B THERIAULT Dr Gilles THIIS-EVENSEN Dr E THOMSON Dr D H TOMATIS Dr L TONER H P VAN DER MERWE Dr H J WALTEMATE H WEJDLING S 0 WILLIAMS Dr DMJ WILSON Prof R YORK J ZOBER Dr M A Atochem, Serquigny, France ICI Runcorn, UK Istituto Superiore di Sanita, Rome, Italy Wacker-Chemie, Munich, Germany Atochem, Brignoud, France University of Toronto, Ontario, Canada RP Recherches, Antony, France Rhone Poulenc, Roussillon, France Saskatchewan Cancer Foundation, Regina, Canada Petroquimica, Salvador, Brazil Atochem, St Auban, France NIOSH, Cincinnati, Ohio, USA University of Manitoba, Winnipeg, Canada Hoechst, Frankfurt, Germany Diamond Shamrock, Dallas, USA CMA, Washington DC, USA Shell Chimie, Berre L'Etang, France University of California, Berkeley, USA Llandough Hospital, Penarth, UK NCI/NIH, Bethesda, Maryland, USA Somerset, UK BASF, Ludwigshafen, Germany Arabian Petrochemical Co, Saudi Arabia Hoechst AG, Frankfurt, Germany University of Louisville, Kentucky, USA Huls AG, Marl, Germany Air Products, Allentown, Pennsylvania, USA Huls AG, Marl, Germany McGill University, Montreal, Canada Norsk Hydro, Porsgrunn, Norway Cancer Treatment & Research Foundation, Halifax, NS, Canada IARC, Lyon, France Society of the Plastics Industry, Washington DC, USA AECI, Sasolburg, South Africa BF Goodrich, Cleveland, Ohio, USA Norsk Hydro, Stenungsund, Sweden BP Chemicals International, Barry, UK Harvard University, Cambridge, Massachusetts, USA EVC, Brussels, Belgium BASF, Ludwigshafen, Germany From: Dr B Bennett, Occupational Health, ICI Chemicals & Polymers, Hillhouse Site,-PO Box 4, Thornton-Cleveleys, Blackpool, FY5 4QD England CMA 010703 CONFIDENTIAL Subject to Protective Order In Ross v. Conoco, Inc., Ho. 90-4337 14th Judicial District Court Calcasieu Parish, Louisiana CONFIDENTIAL register op cases of angiosarcoma of the liver due to exposure to vinyl chloride - REVIEW DATE 1 JANUARY 1990 PREFACE : ACKNOWLEDGEMENTS, SIGNIFICANT CHANGES, COMMENTS AND REQUESTS 1 The 14 new cases in this Register are: France 26, 27, 28; Germany 33, 34, 35, 36, 37, 38, 39; Spain 01; UK17, OS 42,43. The Spanish case is the first notified from that country. 2 The following 2 cases have been deleted from the Register: Germany 26 (Alcoholic Cirrhosis), US24 (Cholangiosarcoma). 3 There are amendments from the previous Register against cases: France 22, 23, 24; Germany 31, 32; US33, 34. 4 I thank the following for information about new cases: Drs Lagast, Contassot, Friedel, Tenkhoff, Lee, Hamill and Mr Roy N Johnson. For information about other cases I thank Drs Dietz, Fendel, Smith and Williams. 5 So far as I know the following are still alive: France 15 and 28; US33 and 36. I am grateful for information on this subject in the past year, and urgently need to be kept up-to-date, please. 6 In Table 3 I have now treated a 'cluster' as 3 cases instead of 2, due to the passage of time and the increased number of cases in the world. 7 Tables 4E to 4H have been amended, as the number of cases per factory has altered. 8 A new Table 16 has been introduced showing the number of PVC factories in the world so far as known to me. Please keep me informed of any alterations in ownership, openings, re-openings or closures (see Tables 8 to 15). 9 The initials of case UK05 have been amended to RK (not JK). It will be seen that certain cases have no initials against them. Can anyone please help with this? Some of the countries concerned are Belgium, Czechoslovakia, France, Sweden, the US and Yugoslavia. 10 CHOLANGIOSARCOMA As stated above I have deleted US24 which was a Cholangiosarcoma, not an Angiosarcoma. I have heard of another case of Cholangiosarcoma but the significance of these cases is not apparent in connection with VCM. I should be grateful if anyone who knows of any other case where the patient does develop Cholangiosarcoma with VCM exposure, would inform me about It. CMA 0 1 0 7 0 4 11 RESEARCH Please keep me informed of all relevant research and if possible send me copies of Reports. Would recipients of the Register please pass on this request. 12 Please also notify me of all changes relevant to the Register and especially new cases, for which a blank sheet is provided at the back of the Register. FROM: Dr Brian Bennett, Occupational Health, ICI Chemicals and Polymers Limited, Hillhouse Site, PO Box 4, Thornton-Cleveleys, Blackpool, FY5 4QD, England COJTFIDEJTTIAL February 1990 BB/BGS Subject to Protective Order in Boss v. Conoco, Inc,, Mo. 90-433? 14th Judicial District Calcasieu Parish, lot:!::;' 'i INDEX Table Sequence Belgium Canada Czechoslovakia Prance Germany I Laly Japan o 3: Norway > ho* Spain o M Sweden O w UK USA Yugoslavia w o pMi S g> Ol Incidence of Cases per annum (Table 1) O .PM.. or2 c-* ^O* ^ * a a CD O e+ c+ Distribution Qby Country 53 of Cases (Table 2) ^PH Pt*L-* 0 * o ^Pattern ^factory oT Cases by (Table 3) nrj- 2r* hd S-r c+ * H* ^ latency Periods (Table 4A) r* ;1 " < H 2 -> & * "? S2J A> ?o 4CL ^Distribution t"4 of Latency (Tables Periods 4U-4II) s si O1 ^CD Annuai Geographical 1ncideuce t ^ OCOJ 3~ -4 (fable 5) Li vi;u ANGIOSARCOMA CASKS (RKVIKW DATIf - .JANUARY 1990J 1 Kjge 1 1 I 1 1 ASL Case Numbers by year of Death 1 (Table 0) 2-3 1 1 ASL Case Numbers by year of first exposure 41 11 (Table 7} 5-10 1 Western Europe PVC Producers - StarL-up Dates vs ASL Cases 11-18 1 1 (Table 8) 1 USA PVC Producers - Start-up Dates vs ASL Cases 19-20 1 1 (Table 9} 21 f Canadian PVC Producers - Start-up Dates vs ASL Cases 1 (Table 10) 22 1 1 East European PVC Producers - Start-up Dates vs ASL Cases 23 1 j (Table 11) 24 1 Japanese PVC Producers - Start-up Dates vs ASL Cases 25-29 1 t (Table 12) 1 South & Central American PVC Producers - Start-up Dates 30-38 1 I (Table 13) 39 1 Australasian PVC Producers - Start-up Dates 1 40 1 (Table 14) 1 Middle Eastern PVC Producers - Start-up Dates 1 41 1 (Table 15) 1 Number of PVC Factories in the World J (Table lb> 42 1 1 1 blank form for notifying new cases 43 1 44-50 1 1 1 1 5l 1 1 Page 52 5t " Vl 5b-5 / 50 59 bO b1 62 6J 64 HCLMlfl J LUmif AMI tuLffsmx m NME ON INITIALS IMff (' Birm oi I2.0J.11 Sulvef o 3: > o M (S Sd S 9 &O t* u 8n p far ? W ^ c+ HCD n. o o TJ m y; - tt M fc) lJ * tej fi> Po kO & o a> j4 co e* 03 3 -n! t* Solvaf I IVMt i'<L (Kt'VK'W lluli* : i kMiu.trf ITHJ> II 14 HttST Vf EXPOSURE 00.07.58 DATE Of DIAGNOSIS U.0?i.76 AGE AT DIAGNOSIS TEAKS OF EXPOSURE TO DIAGNOSIS 16 TEARS or exposure HATE or DEATH HISTOLOGICAL J ESTIMATED J CONPIMIATIUN j EIPQSURE | OCCUPATION j I.EWX j ----------------------- 1------------------- 1------------------- inmjt j CRRKER I iiiaa.iu.ns I imio ciaawrrs es \ High jRulucleaner OriJler id a Itlepdlh tests I |H r foundrf |in o<:t mi | 195H- 196H | | expuned tufPidfeorlter \ XX) ffm ji |rs (7 |rs) raraer (15 |rs} Jwere imnat. |Ret.red |Feb 1975 ] fnr H fars ] I l*r da| | j and j | certain.| | Wurk in glass iHnsptlaJised ind. A ctieu- |Ha| 197b cal industry I |Ui^>le1e j under ) |cjjnical and I MM H I Jcareer details ) in 6 to J i %* i 1 autoclavest | iwa-1972 j } ejtpused lu| | 90-MU ppnj | 6 hrs per j I dar in I^ | I jare given in a | paper i>F fllublet e( ai | in Rich. belg. IMed si*c.r |ll|g. Med. Jlrav. Med. |Leg. (1977 pages I autuclaeesi ( fm-im j j exposed tu| j 50-20U pfnij | in auto- J lull-t,Z7 I I I I clave roanI | 19/1-100 j i I | 1975- 50 ) i k i | RETIRED I | I Feb I975| .feaeppe 21 10 61 j 06.62-01. |Aulocleaner | (*J 01.67 jrs 5 atha J -Ul.71 > |Operator j 200 pf J I ft a Salks- t tthAW I | 04.61-12. J j 6b v 200 j i tt* i ii t j1st sign July |/S: Ttuirarir. Jpaio U/./S. flAipatic tests loitered 10./S. |t'tiSil ive fuchograptif 111.74. Hepd- 02.60. [CheMiiherdpv. JItil UESUt iun ((j i veti in Ivtlei I 7 Mrv lW lie Or It1 lii.Miver iUaje tl Sheet l UVtS Anginsarcra Cases * (Review Hale: J Jan 1490) UAY - HUtfTH - 'ik.hk AH dales use UK. syslea ------------------------- 1-------------------- 1 1 I2 I 1 11 T cuuwry AXB I KMC OB DATE of reference | initials Siam NO 1 I 1 1 01 1 1 1 lb.12.11 1 1----------------------1----------------------1-------------------------- --------------------1------------------ 1--------------------------- 1---------------------- 1------------------------ 1--------------------------- 1------------------------------ 4 b|6 | / | S | 9 10 | 11 | 12 | 11 | 14 lb 16 1111 ii IIII IIIIII 1 HOST VC I om OF 1 Aft it YEARS OF YEAAS OF | DATE ft | HISTOLOGICAL ( ESTIMATED | j (mtEll j OTHER COfPAHY FJkCTC*If exposure | nitons is | m tons is EXPOSURE TO EXPOSURE j DEATH j CONFIRMATION | EXPOSURE j OCCUPATION j CAREER j COMKVtS t1 DIAGNOSIS 1j j LEVEL j | HIGHLIGHTS I lI 1111I I 1| | 1 ----------------------------- SHMUl ISM 1 11 1 1 1 III 1 1944 I9bb 41 11 02.09.55 | Yes | [Reactor joperatur [Sauker | | j cleaner |polfaerisat ion| 1 1I 1 1 o z > o (- o SI o Si 02 Qb.4U.l4 1943 1957 43 14 14 21.J2.57 | Yes | fMaintenance, [operator [Worked | | jai Jlwrigbt, | juvertiae 03 26.ft.19 | | |pipefitter | |SnAer 1 lit I 1 I 1------------------------\--------------------------- 1------------------------------- mi 1%2 42 21 20 23.03.62 | Yes | foperalur, | |Uurked | | jforeaan f J over 1 ime j 111 |Won-*uker _____________ ___________ ______________ J 11 M |.04.19 1 11 l______ ___ L____ _1 i 1------------------------11---------_----------------- 1-l------------------------------ 1945 1967 40 22 22 21.01.68 lem | Reactor [Operator, |Worked 1 cleaner [forrun, | overtime 11 11 11 11 ft (07 .ft. 11 | 1944 I960 i 57 j 24 1 ft |ft.07.68 1 1 l1 Tea ( Reactor |eater cooling |Saoker [unit [ ll \1 |Water cooling [worked 11 11 11 1 1 ft |15.I2.I9 | Ii 1947 1971 1 i 1 1 51 | 24 1 1 1 1 1 | 21 10.04.71 1 1 1 1 1 Yes | | cleaner 1 [Reactor | cleaner |unit | |overtine [Snoker 1 [Maintenance, |ailJright 1------------------------------- | Worked * |overt me 11 11 11 ____________ _________________________________ j 11 _ 1 07 (09.11.19 1 1946 1972 51 | 26 j 25 24.12.72 | Yas 11 11 | 11 _____________ 1____________ ______________ 1____________ _____________ 11 oa 1 lll.ft.20 1 1 1*1 1973 11 | jj i1 1 f 51 j 12 | ft 12.06.73 | Yes 1t 1 [Sker 1_____________________ _____ _____ 1________ ______ 1 _1 11 1----------------------------1------------------------------- J [Reactor [Machine shop (Worked | [cleaner (operator and [overtiae || |pulf unit ill Ilf | | Reactor |Maintenance |SaoUr J 1 |ln plant 11 11 1_______________________________________________________1____________ 1____________ 11 11 00 | ||9.07.21 1i 1974 1I |1 11 1 _1 \ f l 1---------------------------- 1 53 | 28 | 26 j(H.09.74 f Yes } [cleaner _________________ 1 1 [furnace up. ]Machine shop |25 jrsJ Saufcei __ 1 1 I----------------------------1----------------------------- f [Mucked ii 1I f 111 ) [pipefitter | juvert tae 11 11 11 1 III [ (Maintenance [ ______________ 1_____________ 1___________ ______________ 1----------------------1--------------------------1-------------------- 111J11 [Swfcer * Paper b( Ur K DELORME in Annales d*knatisue pathuloyique Paris, t97fl Yol 23 Hu 2 pplUVlH daias Ibis case had both a hpi<*q^a and ASt, swltmeuusit- ! ?<**' CANADA LIVER ingiusarcona Cases - (Review Gale; 1 Jan 19*90) Sheet 2 1 t1 ii 4| coumry and REFERENCE K> UK OR | DOTE or INITIALS j fiitm j 1 4 ------------------- j COViNY r--r > 1 6 7 LL V 1 FIRST VC j MTE or factory | UFOSUtE | DIAGNOSIS i L l_ 1 1 I------------------------- 1 8 9 JO WE IT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS YEARS Or EXPOSURE 11 DATE OF OEAffl 1 to |lb.05.15 SfawiBign 1953 1976 61 23 14 00.04.77 1 1 j 1 XL 1 II jl3.10.25 LG Gulf ShwInimM 1941 Nov 85 60 i 42 5 05.04.86 i i 1 ______________ L 12 BC 14.08.20 Gulf Shawiatgen 1945 tor 82 61 i 37 1 31.0i3.82 i i i i il 1 j i( i i L 1 n 6010.06.26 BFG Niagara | 1957 1987 30 23 26.1.87 t jNttliwi Ii li Ii UliY - nmmi - YEAR 111 dales use UK sfstuai 1------------------- 1---------------------J2 1 13 1 H j 1 ii HISTOLOGIC*!. | ESTUtMD | j 15 OTHER 1 1 16 _J----------------------------- | OTHER S 1i | OCCUPATION | CAREER | ccmcnts | LEVEL 1 1I iT l1 | HIGHLIGHTS i i -i----------------------------- i l1 i Yes I iHeactor [furnace op. |*-wker I 1cleaner [Maintenance, 1 11 (packaging 1 t i l il-------------------------_|t II 1 Yes 1 High |1941-47 | Retired 1972 (Letters team 1 [Operator 6 jlftge 47) |Dr Fernand 1 [Supervisor Jbelorae, 1 |vc Plant {pathologist 6 11 Jll 6ibeau, RFG 11 1 T 1l 1------------------------- i----------------------------- Yes 1 High 11916-65 {Retired 1972 [Letters frus 1 |Autoclave lt*ge 62) |0r Fernand 1 |Operator, 1 jpvc Resins jDelorue, (patholugist 6 11 jH Bibeau, 8H3 | Low 11966-66 I I |vc i I I | Kadius {Manufacture | 1 |1965-72 I 1 I l [Autoclave l 1 [operator, l [PVC Resins I "1-----------~it---------- 11----------------- Yes | 1957-70 |pol| Cleaner |Retired 1980 [infuraat ion i Hi* |b Operator |(*ge 64) |fn 1i (Dr H M Dietz, | 1970-80 j Low [Supervisor j |AFG, 1988 l O 3: > o H* o Nl O CD X 1 11 1 1 I II l i II ill i ii ii ii ii it ill til ill ill ill i i i i I ii ill I j------------------1ii------------------- 1i 1 I1 ill ill ill ill ill ill ill ill 1\ 1\ ill i ill i ill i ill ill i i ill i ill ill i i CZECHOSLOVAKIA UVEA Anyiosarcxma Cases - (Review Dale: i Jan 90) courm uc MK OS DATE OF REFERENCE (HTULS I Sim cmm CZECHOSLO VAKIA 01 I l2B.0L.28 l i State Co U2 06.07.27 State Co FACTORY first vc j date of EXPOSURE I DIAGNOSIS I AGE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS 10 YEARS OF EXPOSURE DATE OF HEATH +12 I HISTOLOGICAL | ESTQIATED CONFIRMATION | EXPOSURE occumioN | LEVEL 01.Q7.b7 24.12.73 45 16 24.12.n Autoclave Cleaner Novakf 01.11.50 27.11.64 14 15 26.11.61 Autoclave Cleaner ib I lb other cueer HIGHLIGOTS j | I other cuwirrs H-----------------I |1ARC letter <d |1-4-82 giving (details fria (Prof A David (uf Centre Ind (Hygiene and |Occ diseases. t -i------------------------------ I |IARC letter of | 1-4-82 gave Isuwetkit |aJUred dales Jfor this case- ji have [accepted the |changes since |(he dates uk | fra* Prof |A David ol the |Cent re of |Industrial J Hygiene and |Occupat iuoal {Diseases. fty |(Liles coae |urtgiiMiJ]f |trim H10SH. C O N F ID E N T IA L S ubject to P ro te c tiv e Order in Rosa V. Conoco, I n c . , Ho. 9 0 -4 337 14th ju d ic ia l D is tric t Court C alcasieu P a ris h , Louisiana ox > Nl o >0 1 FRANCE SteeH LIVER Angiosarcoaa Cases - (Review Date: 1 Jan 90) I 21 courm and m mruLS DftTE OF Uli 4 oovin 5 factory ___--------------------- 1---------------------- 6 7(a i______________ 9 FIRST VC Dm OF OIAOKSIS 0GE IT Duaosis YEARS OF ansnc to DIAGNOSIS i------------------1 --------------------------- 1---------------------- ----------------------- 1--------------------------- ,------------------------------ to u 12 | 13 14 | 15 | 10 1--------------------- 1 11 |l " i YEARS OF Dffi OF | ESTIMATED | OTHER | OTHER EXPOSURE DOTH I i | EXPOSURE OCCUPATION j CAREER j COMEMTS LEVEL J HIGHLIGHTS | .______ ... ----1--_--------------------- 1---1--------------------------- oi H 15.04.3t qusolllOD 00.01.40 10.02.07 41 21 19 19.02.67 Vu Hi* Autoclave worker and |ftef. Ravier et |al Arcb. Mai. |Prof. 1 30 a' 19 yra |3 Nov 75 ! |p 171-177 i If ia sn 01.00.11 pa* rigaml 00.07.59 15.01.75 63 10 12 24.01.75 | 7 High 2 fra on Italian |Ref. j (OIOSH bo origin |G Boweton et 1 C0~t> 10 fra on |ai *%juvelle pol|w Ipreaae 1 iaation InecUcale" 1 |5 Nov 1977 1 |P 715 11 ----------------------1----------------------- , --------------------------- 1i------------------------------ 01 HhW 00.01.30 0P St Fans 00.00.40 15.01.75 55 29 29.00.75 | 1u Hi* |PoIymrker; VOI productloo)Ref. Keif et l J10 fra aa 16 fra. Jai Arcb. lb). 1 | autoclave Italian PON. jpruf. 1 17 o' 04 MOO ___ 27.01.37 J PCI* t ftrigooud 19.10.49 ___ 10.01.70 ( 1 49 2b 1 I 1 1 1 30 04.01.70 | TttS 1 ]cleaner! Shephard, |6 June 7? Icoymdinj Sawyer, Haaon jp 551-555 |3 yra l 1----------.-------------I-------_-_--_-_---------------- ,--------------------------L1---------------------------- High |Hnnfar | | |product ion | j 11 1 {worker | | m dO> *M !-> a C3f* *4 aP* ao) aH<>o- cu o *+ c+ O o o as pax) O4 o M fc* -tr J2 to t?3 as of* c^ ga & t+ O-4 '?J o _ to T i--i > tr* p g 2 ^ oO 1 433 w ct 3 05 t 1 1 1 r 1i B 37.01.10 | PCK 1 1 1 1 1 n1 a: 1 >1 ot M1 OI 1 2] 1 ___ l |ltl9Md 1 I i 1 I 1 1 i 1 1 1 IS.01.05 1 1___ 1 1 1 11.05.70 1 1I | 1 1 1 1 1 1 1 1 1 1 1 1 30 1 |6 r. | | 1 [PVC 1 j 1 (filtration j | ! lie | | 1 i 1 | L____ _1___________ _____ 1 11---------------- 11----------------- u 11 |ll.05.76 | Tea | High |Polyworker J1 IThoracotaay |Ref. P Coudere j| | 111 rra |9th Feb 1976 jet at "Swaine II || II || II || 11 |J || || 1____ 1___ j 1_ _ _ | 1____ || jcoetaJ |dea hospitauv || |ogiOMrccM 110 SeploAre || |J || |2)SciaUgra(ib||l976 jfound ASL |Previous!i bad |3)Hfnirhage |boae 11 |fm ASL ]aogiosarixauH I( t4>ti4bL [Also || lUepatectoaf III || | jj 1___ 1 f 1 |Pi Eichuwaki et |al "La MuuveLJe (Presse Hedirale" j/lfa July 19/S h 1 6Page FRANCE ShsU OOUHVtT I ion m 06 DATE OF INITIALS Him 16.06.34 KUt 07 OH 26.06.27 00 01.06.36 Solver i? O rfs. & P> M fOo S *<5! <1L-0 la H- o 0> o p taj JUtJ O ^ *--d M *-$ Oh*J ty frJ S4? t 1 oa 09 an ! 3p pc f" X 06.10. 14 O 3 > O M LE.VEJI Angiosarccna Cases - (Review Date: 1 Jan 1990) FACTORY FIRST VC DATE OF UPOSUU i DIAGNOSIS IclVMMd 01.03.5a 12.00.76 St 01.07.50 after death | 00.07.76 Taaaua 21.05.57 03.12.75 St I 10.01.4 36.04.76 AGE AT DIAGNOSIS 62 62 63 TEARS OF EXPOSURE TO 01AGN0S1S ia 19 10 YEARS OF | DATE OF I I + u |ll.09.16 12 13 I --------------- 1------------ 1------------- HISTOLOGICAL | ESTDtATED | j0QNFIMAT1GN EXPOSURE j OCCWATHJi jj LEVEL H--------------------- Vea | Moderate 1(1958-1960) OTHER CAREER HIGHLIGHTS OPTHER comoffs |This nan had |(10SM |w)i 112.09.76) I |2 irs (filtration 110-11 irs (polfworfcer |AOL prior tu lAS. Ann. de j Hal. Prof, jJuly '77 I (end works |p 615 6 b- | lab? |A0L was found I |in 1971 five I [jrs before 22 02.07.76 I + j High I + (Plant Fore- |ASL H---------------- 1972-6 Un (Died of I I- section is feepi icaenla jjpOllKT- St |Snail liver |Iselion I | lesion found {alter autopsy 19 130.01.77 I I + Tea j Moderate 6 |n pecker I |6 autoclave |cler 116 i + (Had been | tunnel worker jpreviouslt I (autoclave I |worker 25.12.77 Tea + Very Hl<i jpolyner- f10 yrs in (operated 4.7b 1968-1966 lUetloe |sulphuric |for renoval of | [saner {operator, |ecid factory. jtiWAir frcn | Lpoeurs jautocinenor,{storekeeper A |liver and | 1966-1976 {autoclave {general Idled after 1 lealoteoaece |service* {second 11 (surgical 11 (operation for 11 Jbiiio 11 | bronchia J 11 (fistula 11 (Paper by 11 |Dr Relj e< al 11 | in Archives de 11 lHaladei 11 (professionals 11 11 11 J______________ J_______________ |vol 60 No 6 (19ft p*jes (761-i. J___________________ nmX - Sheet 3 LIVES Angiosaroona Cases - (Bevies Date: 1 iso 199U| un or OTTULS 10 24. 06.19 o o \( 15.02.12 FICTQIf FIRST VC 0,12.56 00.01.41 j Dm or DIAGNOSIS 10,01.78 12.08.78 AGE n DUCKSIS VUKS OP ewsou TO DIAGNOSIS vu&s or 21 10,01.78 37 13,11.78 j HISTOLOGICAL I 14 H------------------------1------------------- estwateb | | amt* | OCCUPATION | CANCER | ] H1GK.10HTS ++ (Utfi {Autoclave 110 yes in | cleaner jnoctianical | leoyiDeentK) | |industry 1 |l946-195fe ++ High {I941-194E | tmtfcit cumekts Died of putannery e^Ktiiae 6 (bfi after surgery |pol|rjiHtloa I Jguera) llurpoM JurAer. I 11946-1972 ( |WH I Ispithuii I(NCI t | | |Aa>t|lae) | Ifbntn l(*gt j j |d aiitriw). (1972 |retired 1 j | 12 oM p t-J rf* c+ O tJ* W e o' c. (D JO O to Ch C ct a O m Cu H* O 2 + O 2 ^M* p P h-J h o M H* _i h- w 01 a 10 !?d FET ~ o c+ id c+ K3_ Q H 4 IA <+ O. O O VO '1 O OU gc . a 13 16.08.14 KIK Ari^uud 09.02.49 00.05.79 65 30 - 21.06.79 19.01.31 Solvay Tftven 23.09.63 26.06.79 40 16 13 22.08.79 05-04*24 Chios Cbieie (Fornerly m 29.07.81 High protection ad pol^w isetioa operator Autocleaner 2 yrs aa cycle Cigarette 2l. |Auto- logoratoc b t**. |Cagotiaer3 M r --rhanic. JtO fit u IwMllar lo Moksr until 11974. Ill >11 jut 1977 doe tu fsaoltarf wra luuapCajMl {aaaufactlire |*arlaex. I IjUigial II [iatuwaliw I I II |25.0S./9 I(rl9hl IhepaUctoor) Vary High |J943-I975 |1975-1979 1943-1975 fill types ofjaaioteodace | and Jjobs on Juork Lntenutl-feaeufdcture ( ently Jfc Mintenance 1975-1979 jin VCJI Poly | f | j j fpiucess f J --------- ---------1--------------------- 1-------------------------- i-- Page 8 FRANCE sfrgy \ coumv j IS 16 LIVER Rogiosarcaaa Cases - (Review Date: 1 Jan 1990) NAME 00 OOTULS Dm OF tint + OOP 01.01.37 Chloe l 10 i II | FUST VC ) DATE OF j AGE AT factuv | unsuu | dugndsis j diagnosis ++ YEARS OF jYEARS OF Dm OF EXPOSURE T0{EXPOSURE DEAIR DIAGNOSIS | 05 i 07.07.55 28.09.02 27 27 Alive (fonarlT m 11 14 HISTOLOGICAL CONFIRMATION ESTIMATED LEVEL OCCUPATION Yes Higb-20 jrr Autoclave Moderate cleaner 7 |rs 1955-1962 autoclave operator 1962-1902 GDI 13.07.22 Chloe St Fa 17*. 10.41 05.01.03 61 Chteia (Fonarlr ?> 91 03.04.63 Yes High-13 jrs tol|Wftnt HabfiU- loo Crocus t - 5 |TS Mortar 15 cmeR CAREER tUGAltiHTS OTHER Left Hepatectasi 1961. j c Gontaasot Letters of S 10 61 mod 29 7 00. Retired i 1979. J C Coataaaut Letters of 5 10 1981 and 25 7 04. 17 22.02.2J St ra 17.0S.S5 03.0t.SJ SO 03.0t.83 Mi* - 23 | Health t Safetj Agent Other sectors of St Fobs Factor? 19711978 Retired 01.01.79 J C Cootaaaot Letter of 5 10 1963 cn <3' (nD 11 o o IS l-t c; " o 10 1 i-i P r. OO QqJ> i: rt ^: 14.07.12 I Solvif Twwtt 09.09.63 21.03.09 42 O 3E > Oj ** oi MI * -L w 21 21 27.12.04 21.03.84 Uigfa-12 jra lutoclave Low - 9 rrs Cleaner 09.03.04 Right Ihpatectaq 05.05.8424.09.04 for Luogtaartaais : partial rteisiiuo. 06.84 - liver 10.04 - lung: evoiut juu uf he disease P0 9 run LIVES Angioaarccna Coses - (Beview Date: 1 Jan 1990) ami -------------------------1------------------- -- --I------------------11--------------------1---------------------- 11---------------------- 11-------------------------- -------------------- 1-----------------11 ----------------------1------------------------1--------------------------- 1------------------------------ 11 1 l |2 i 1 56 ? B ________________ 1_____________ 9 10 | 11 12 _____________ 1____________ i 13 | 1 1 14 | 15 j I1 1------------------------- 1 11 1 16 axansy uc m ***** UOTULS uk or BOTH cmm man FIRST VC UK Of Duaosis AGE IT ouansis YEARS OF UFOSUU TO DIAGNOSIS YEARS or | one of j DEATH E0O6UU j HISTOLOGICAL OQHFlMTlflN esmneo | | urosute | occupitioo | utheb cioeeo level | | highlights | j j ___ 1 1 1 othes ctwans EUH Autoclave operator and 19 MI 1S.X2.J2 llodMB ari'pud 07.04.S9 20.10.04 52 25 25 00.11.05 its High cleanar Rfocardial lofarct lun I960.Coronary bfpus I9B1. Utter fron Dr Conterant 5.4.86 C O N F ID E N T IA L S u b je c t to P r o te c tiv e O r ^ r * Boss V . Conoco. I n c . , Mo. 9 0 - 10 14th J u d ic ia l D is tric t Court C alcasieu P arish., Louisiana 2D M 21 h .. , 22 1 IL 23 DO CHA* 0110077114 02.02.23 ItOChM IrlipKMd 19S1 27.12.05 03 24 22 20.12.05 Tm 01.10.10 IT SH> HaBtluaa 1959 02.00.00 45 27 * 20.00.00 las ___________ ____________ 13.00.20 | ilodM St tab. 01.09.50 05.11.07 59 29 20 00.09.00 ( 11 11 1 1 ___________ j______________ ___________ 07.02.27 [ lluctaea St foos 1 1944 | 1900 1 43 | 44 1 11 1 ,1 j 20 . J21.09.99 | III 1 i 1 III 1 1 1 III i 1 1 1 11 1 1 _____________ 1______________ 1______________ 1_________________ III Tea Ves Hlib Portel Autoclave la other parts fibrosis fron operator and of factor} cleanar lacs 1940 26.04.74. Tbe llinaaa was dieynewt as pronnaMf work related on 20.04.74* Utter fron Dr Contasaot 05.04.86 | Hl*i Autocleaeer Maintenance Hepatic teat 1 4 yeara worker Maf 84 noraal. 1 Hepatic test 1 Itav 86 afamed 1 absonaHt lea. 1 Utter fron 1 Or Barrat 1 18.07.86. | i<* 12 feara 1960-70 Autoclave indwr. i Low | 14 fears to J 1970-04 | Control Socnj High Jiutoclaw | 1 jt'leaner 0 j 1 jail PVC | |productlun | 1 |J<2>4 | 1| | Letters fron Dr Conlassut, Itocfaen 2-12.0/, i 29 / 0B, 24.01.09 [partial j Nepal ecttaq, pr |S0, CtmButherapT | Infiranliun Inu |0r J C Cnnlasaul, jaiixdn, L'jbs/os Page lO fife?*1 Skeet 6 LIVES Snglosetcc* Cases - (Review Date: i January 1990) 1 1 23 4 56 7 8 9 10 11 12 13 14 15 kb COUTH AND IK Oft om or 1KT1ALS IURH 0 OQMPin FiCTOIl FIRST VC YEUS or om or AGE IT UVQSUHE years or DIAGNOSIS diagnosis to DIAGNOSIS om or death HISTQLQ61CAL ESTW1B) coarimnaa occupation LEVEL OTHE& raacra HIOUGNTS CPTIS6 CCMEHTS 24 Hi OS. 12.26 Itnrtw Irignwi 1943 I960 62 4b 35 01.12.86 Tea Hi<*i PVC Product LOO Liver transplant Hay I960, - 2 fears intonation frta Dr J C Cootasaot, 001 8CV Delecti Stock*, 1988/89 - 3 feara PVC Product ICQ 1 1 aiutaoance 1 ; - 30 feara j 2b 02.03.30 Solvaf 1962 19SS bS 26 23 07.ob.se Tu 11 jeers) Polycleaner bHigh) - jeers Poljfioor 1 - 6 jeers 12 fears Control Sots Low > - 12 jeers Priaarj Liver Tiaour Halaataaea lung, brain, bone, spleen, Icicbej. Intonation iron Or H Lagost, iSolvaf, Hoveaber 1986 26 MB 29.11.40 Solvaf Twraux 16.04.63 2b.10.88 48 fed S S?E 3 g. 37 oaj t>* f* O ) 2. r? 9 ** o s g go S * s r?^ 28 3- *3 S H- fj nm 2 g. y o S ,TKrf ` ri-+1' t*->3-* g* & a 2 o S' > & rt- o tr< bo 2^ 2. rt ,'J -,' BC JG C:l a o o SJ M. 1929 Slock* St So* 1994 1926 Stock* St Poos 1942 1968 59 1989 63 25 15 02.11.86 T High Autoclave 12 ram Low 3 pvt for 15 fears 34 30 00.01.69 Tea 195474 Autoclave High Cleaner and 1974-84 UM all PVC pruitctloo >obs 47 20 Alive Tea 20 yean 10 years High antraer aoalfsis (laba) 10 fears production PVC Died bf haanorragic rupture of the tunour. Bo surgerf. Letter froa Dr 6 Lagast, Solvaf, 26.4.89. Notified bf Dr Contaaaot, Atocban, faffidwr 1989 Notified bf Or Cootasaot, Atochen, December 1969 J. P9B VI awu l----------- 1------- 23 dm or UTTULS 01 00.00.30 02 00.00.11 01 00.00.30 12 M 00.00.30 I o 3 > O LIVkJl Aogiaearccaie Cues * (levlew Dele: l Jan 1990) I 10 HI 12 13 fust vc j ora or | DUGH6IS MSE IT 0J4GHSLS VEUS OF QFQGHRE 10 DUGX06IS 9EABS OF Elffi W Km HISTOLOGICAL esrouteo arosau LEVEL OCCUPITIGB 15 l UTHU j CUEEt | HIGHLIGHTS j one 01.10. so 19.09.68 12 12 25.01.69 fas (H10SM) Polyworker I 14.10.S7 2S.09.70 39 13 14.12.71 las (MI06H} 12 09.0S.S2 00.03.73 43 21 16 10.10.73 (H1QGM) Polfunrber ruling pesticide eeranol c wltb VC H----------------l {Reported under I non poljner|Lest Ian |sorters lii ftfJOSN list of |3I.3.77. jTbu of course j is strlctlf |correct. |Housver 1 16.04. S7 26.11.74 Jwbetber ibis jnu bad higfa /exposure to | VCM in bis Jean filling j operation? _l-------------------------- t 17 17 25.11.74 (06H) 200-500 pn Polfworker 6 958 us |cllnical but Ugh tn^nrerr eutoclesner |delaiU in during 1 |r eutoclesner for I yr nutocloaner |p*per bt joakal al .1 IllrcSn tret jl FUi 1976 1172 p 194-201 I I mm r Pus 1- OFIHUR SbfisLi l 21 coarm mu rn mruLS Dm OF 6JXTM os (OIOSN gi*w M Cm* OS) 00.00.36 OS (nasi si*** Cm* OS) 07 00.00.12 00.00.20 n 3 06 > 1 100.00.1/ o o1 Nl ---- 1---------- J LIVER lngiosirca Cams - (Review Date: 1 Jan 1990) 4 aan 1---------- ----------- ,------------5 6|7 _______ 1________ ncmn |FUST K DATE 06 DIAGNOSIS 1 a AGE AT DIAGNOSIS 9 VEiftS OF DIAGNOSIS u li 02.04.60 10.12.71 36 1 u T 7 16.12.62 00.00.75 4) 13 49S 0 1S.04.S4 12.11.75 21 . ______ _______ | j4 19.07.S4 t 06.04.7S SO 11 11 11 _______1________1________ ________ 20 10 11 12 mss or Dm OF HISTOLOGICAL oavoNnriw 05 16.12.74 y* (nan) 11 13 14 | 15 | 16 --------------11----------------I-1----------------- eSTHKTB} } OTHER | ones EVQSNE OCCWATIOi 1 CAREER j CQMHTS LEVEL --------------1i1---H--IG--H-L--IS-f-T-S-- j 1-*----------------- | ) Confined BG Chnaie Mfs Mmi rtcr i J | t i J Reported under |mo-polfBec" final loo laboratoriaoj Jworkera in Id the Tectioo- | j ofjSlOSH list j31.3.77 and logical | fteaaarcfa j |Dapartaefit" (MIQSU aajs | |k .70. 1 don't | think this is fa correct |claaaiftcaUuo auUtaot | factorf | deaiil | Kbit* aaf bej |b| IROSH. The Jau ear have |faeen involved jin VCH 12 09.01.75 21 (naoo 11.11.75 *r i2) i 20 l2S.12.7S 1 1 1 1 l rang | |pol]Krtsat tue translation)] (in pilot plant I |or in aain l i-------------- 1!----------------ijrp-l-w--t-.------------ te* |wc - N*U' 1 jfactrn 1 |Shift Loafer 1 11 1 1 ---------------- 1i----------------- Im (OK Hmu 1 jfacture Md 1 |*11 work | iocl auio- 1 1 Jcla*oi*g |12 tr 1(19(54-66) 1 1 |rora**o ftch 1 }&ev 0 frs 1 |(I%7-19TS) 1 11 1---------------- 11------------------ 7m ? |1 |Ful|wr6*x ? | III III iIIt I1 1 1 11 NJ C O N F ID E N T IA L S ubject to P ro te c tiv e Order in Ross v . Conoco, In c ., No. 90-483 14th J u d ic ia l D is tric t Court C alcasieu P a rish , Louisiana r courvtv , HO UK <* nan op mriALS 09 00.00.34 10 (IIOSM giwa a* Caaa 11) 00.00.36 nM p #--< c+ foa tr ca *-H H* c CD pj H* O H* P M* Ul a to1 ta rh *'S o Ho td o cq CO cr ca o! C_Ja < o o o c+ o Q o i o 3 <D H* <S O i o o si M t) t?d !2i t-3 1--1 tr* u (H106H gives m Caaa 10} 12 o > o P o r-t> p OCO) t3? -4 O si to 00.00.29 00.00.36 UVEA ingiosarcaaa Cases - (Review Dele: 1 Jan 1990) pactuv T-------------1-------6 7a fust vc Dm op AGE iT DUOKBIS Duansis 20.02.61 16.06.76 41 tears op UP06UU TO DIAGNOSIS IS 10 I 12 ---------------- 1-------------------------- TEARS OP 13 MR OP I HISTOLOGICAL I I ---------- 1---------- I I 21.03.78 I I res ESTIMATED occwanoH LEVEL I -I---------------------- I t High peaks (12 frs pair Iwrku incl jm auto- OTHER CAREER HIGHLIGHTS OTHER oomrs 10/70 Copfirued Average 21 t 01.01.61 00.01.77 1016 07.03.77 Hit*) | claw (cleaning (Caatrol roci |l ir I I -|---------------------- |10 jrs polT [sorter incl |l7% aula|clave exposure first 8 ira IW wm, ucc 1000 pf. Rest 3 jrs av, 7b pfm. Last. pr av 3b ppa Average exposure first 9 prs ISO w, occ 1000 ppa. clawing last jr av 7b ppa. CWH letter of 21.04.70 2210.10.55 20.06.77 47 21 26.06.77 00.00.61 00.10.77 + 16 07.10.77 Tea |PTC Haw- fleeture |Autoclave fworter for |6 jrs I I > Pava 1J1 G0MIT Steel 1 1 -- ------------------1 i3 4 ooumi ud m mruLs un op lUN covin 11 00.00.14 7 m> is i i (HQSH 1h| tbia aa j Caaa 13) j 1 n > o h* o si <0 00.00.29 8 ___________ 1 LIVER Angioearccae Cases - (Review Date: I Jan 1990) s rician i a 6 FIRST VC 00.00.80 1----------------------11 76 9 am op DIAGNOSIS AGE K DIAGNOSIS YEARS OF UPQSGRE ID DIAGNOSIS 00.04.78 63 18 10 11 12 YEARS OP UPQGStt am of OWN HISTOLOGICAL CONHRNtriQN 14 19.05.78 Yu 1 1 13 | 1 14 | 15 1______________________ _ l ii Esrurno | j otom EKOGUtE j OCCUF4TIQM j CUEBI 1 | 16 --t 0THE8 oments LEVEL | | H1GH.1GHTS 1_________________________ 1 i--------------------------- 1 F W best 1 letter of ) 30tb June 1980 1 eoclufliag dala 1 frcm 1 Ik H P Frledel l of BG dale Not M Aagionroaae la Ids letter oT 21 12 81, Hr rrladal aaid this na a "PUUaoapl thaltarilw Oar Spalaarcbra* (a carclnfa of U out attribut es to 8 ant noofUud aa an iatbrstrlal dlaaaaa i---------------------------- 1-----------------------------| |F U Beat J flatter of j jlOtb June 1980 | feocloeiiig data 1 | |H P Frieda1 of j |BC dale | |wllbdrowing | j tbie case 1I 11 11 1I 11 11 11 11 11 i 19.10.S3 09,10.78 49 25 25 23.10.78 | (aa 1 1 1 1 1 1 1 ___ 1______________ 1 ________________ 1 ______________ i ___________ 1__________________ 1 1 1------------------------1------------------------------- ? (Autoclave | fAngioearcue j cleaner end j joottfiraed jwuter. | 109/79. Suee |Drier (operator. jLater shift | | | jdetail of this |t eleo cases |9f U, 15, 16 | leader | i | |& 17 given in | InW Report fur i___ r___ C O N F ID E N T IA L S ubject to P ro te c tiv e Order in Ross v . Conoco, I n c . , Ho- 90-4837 14th J u d ic ia l D is tric t Court C alcasieu P a ris h , Louisiana r age |r germant Sheet 5 LIVER Anqiosarcuaa Cases * (Review Date: 1 Jan I49QJ H COUNTRY , SUB m IS turn, at DATE Of INITIALS BOTH 00.00.23 j MAST VC FACTORY j UFOS4t DATE OF DIAGNOSIS AGE AT DIAGNOSIS YEARS OF EXPOSURE TO DIAGNOSIS 10.01.55 07.06.78 (Lelhach 55 23 ASL at Fab 1975 laparotomy) DATE or DEATH HISTOLOGICAL CONFIMATIQN ESTIMATED EXPOSURE UVEL 07.06.78 Yes ASL and Hepatocellular Carctma High Autoclave worker till l%4. OTHER CAREER HIGHLIGtfTS (JTHLK cuwirrs Ilnyii (confirmed, (lull details (of illness |since March (19/3 given is lU Hed Insp |Rep lor 19/6. (Different |details given jin "VC (Associated (Disease* hf |Le)bach and Jltarstelker (1961) pM. C O N F IP m iA Ll S ubject to P ro te ctivG O rd^r i Boss v . Conoco, In n ., Bo. 90-4J 14th J u d ic ia l D is tric t Court C alcasieu P a rish , Louisiana 17 {KIOSK given as Case IS) 00.00.37 OI.il.El 14.06.76 26.06.78 Autoclave worker |Angiosarcona (confined. (Annual report |of the North (Rhine (Uestphal ra jMedical 1 Inspectorate |for 19/fl |pages J4/- 1/7 (gives full |details. Vinyl (chloride (disease (diagnosed |U2-Q2'/1. (Ousofihageai |varices, jRadiological If jcunfirmed aero [osteolysis. o 3: > 19 o Nl o 18.10.54 24 25.12.79 Uituclave 22.02.U0 Yes Htgk Worker Autoclave +jur Netastasing Worker | letter uf ASL |H (M B; to |Ur I* 0 K r H "1 01 cGf o o y i- i GERHRHV 1.1 UtE ingiosaccona Cases ( Review (lets: 1 3aci 1990) Sheet 6 1-- 1 12 * _________________1_____________ 1 1-------------- 11-------------------- 11----------------------11----------------------11--------------------------11--------------------1 s6 1 a 9 10 11 1------------------ 1--------------------- 1 ------------------------ 1 ----------------------------1--------------------------------------------------- 12 11 H 15 | lb ----------------------------11--------------------------------------------------- HJSTO 1 ccurniv aid REFERENCE m UK 0* WTI1LS DATE Of FIRST VC BIBIK conn racrar EXPOSURE WTE or DIAGNOSIS AGE AT DIAGNOSIS TEARS OF EXPOSURE TO DIAGNOSIS TEARS Of EXPOSURE DATE Of DEATH LOGICAL CQNFimAT10N ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER C48EEN | j HIGHLIGHTS j OTHER CUMKIfrS ii i---------------------------------------------------- 20 00.00.15 4 4 14.012.61 00.04.00 6b 19 13 19.10.80 Tea High |autoclave | [Orfiesche tetter of Hmmangio juurlcer | 113-04-82 to EndothelDJna | | |0r H U F 66ms of liver -1th | | | Hetastaaei 1 1 1 ________________ _____________ __ 1 1 1 1-------------------- 1-------------------------- 1------------------------- 1-------------------------------------------------- 21 1 00.00.13 4 4 01.01.62 00.09.29 66 ia 13 19.06.80 He* J High |autoclave | |llr Bescbe letter ut 1 pronounced llm--ngloj |Uorker end | |l3-04-82 to 1 cl inicel Codotbeliaaa (wotted in 1 |ur H G F `A -- 1 liver t or liver with Meteeteeee |tlr jiog shop | jj J J -1 00.00.21 * 4 IS. 10.61 2B.OB.OO 59 1i -i---------------------------i1 -- 19 11 06.12.81 Tu high Autoclave Chargetiand, Ur Besche letter of NeUrtuij8) ASL Murker subsequent if Foreman 13-0482 to Or U G F Addms 23 24 ________________ 1 i 25 | I 1 ------------------126) ------------------a n ^ 3>- " O >J to 00.00.2? & 6 1965 20.03.79 52 24 21 29.09.BI Tea Nigh Chemistry Primary hepatoceliar (>300 ppe> Murker carcinoma; proliferation of the sjousjodaj cells villi 1 i sinusoidal ectasia. i Friadel letter 23-12.06. 1 1 1I |(JO.00.28 1 8 1 S 1 1969 1 III 1 III 1111 l iii |00.00.23 j 6 | 6 | 1560 r 11.10.82 i | 28.09.81 1 | 54 1 11 | 13 j 12 11 28.05.83 ----------------------1----------------------- 1 Tea High 1 autoclave | (>300 ) jcleaner J 11 1 jj L 11 i---------------------- 1------------------------- 1--------------------1------------------1------------------ --------------------- 1----------------------- 1 j 58 j 21 | 13 jl4.01.Kll fee High jPolfclave j __________ i (Prof Cder (Meucfi) (letter 22.U8.83. (friedel letter 19.04.86. ; l^rof Seleelr (ftnich) t 11 1 1 1 I III jilorker and j | letter 22.08.83. 1 11 1 1 1 1 III! |lutoctave j Ifriedel letter 19.04.85 1 11 1 1 11 1 1 11 (Cleaner j 1 -------- -------------------1-------------- 1-------------- 1-------------------- 1--------------------- 1----------------------1--------------------------1------------------- 1------------------1------------------ --------------------- 1-----------------------1------------------------- --------------------------------------------------- ) III 1 | j | |Deleted on advice ol UT Tenfcboff December 19S9: 1 f i|| | | | J jAlcoholic Cirrhosis, not VCH associated. J { ---------------------j-----------------------j---------------------------------------------------------------------------- --1---------------- 1-------------- 1---------------- 1-------------------- 1---------------------j-------------------- 1--------------------------1-------------------- j-------------------- 1-----------------j (uu.uo.28 | 4 | 4 | 1955 | 1a.01.aj | 95 | 2# | m jo2.03.g4 j tes | 1 11 1 1 11 1 1 11 1 III 1 1 1 lilt -------- 1------------------11111----------------------1l11---------------------------------------------------------------- L High (autoclave | (Cleaner till) Leltach. (fried.! letter (1912 1 (19.04.85 1---------------------------- ---------------------------- -------------1------------------------------------------ -------- Page * / LIVER Angiosarcona Cases ( Review Dale: i Jai 1990 ------------------------- 1--------------------1------------------ --------------1 1 2 I3 4 -- 5 -- -- --------------------------1-------------------- 1 6 7* 9 10 11 COWRY JUD REFERENCE r UK 08 inriiLS ohe or FIRST VC Bim conn tinoai ERN68U Dm OF DIAGNOSIS ICE IT DUGWGIS TEARS OF EXPOSURE TO DIAGNOSIS TEARS OF EXPOSURE DATE OF DEATH 28 21.11.21 7 7 01.10.80 11.08.86 81 26 26 25.OR.85 29 00.00.22 2 2 1982 16.02.83 61 21 19 15.02.84 i 12 j 13 1 1 HI STD | LOGICAL j .ESTIMATED ----------------------- 11--------------------------- 1--------------------------------------------------- 14 15 | 16 i t t OTHER l OOMF1AH-| EXPOSURE ATION j LEVEL OCCW1TIQH CAREER | HIGHLIGHTS j OTHER CGHKEVTS 11 _______________ Yes HI* Process worker |I |Annual YCH screening (24.04.85: nooo^ilaint, 1974-84 |no eboonelitf detected, j1920 two-thirds 01.10.80 31.03.84 nc production, agitator area IgastrectuHf for ulcers. |1971 Coronary thronbosis j 1983 Fenoral |l^))aoUUoa [1984 PuXeaoary eaboliai [and pleuropnetBonia. (Landers letters 18.09.85 jand 04.02.87. 1 Yes High Oauitrf worker Haenaogiosarkaaa. Friedei letter 23.12.86. 30 00.00.17 4 4 mi 07.01.00 82 29 26 26.06.83 Yu HI* Polfworker Hasnangioearkaw. Shift leader Friedei letter 23.12.86. 31 00.00.21 0 0 1963 30.08.86 61 32 20 31.01.86 Yu HI* Autoclave Heesttag ioearkaea. Friedei letters 23.J2.Bb, 15.11.89 6 Feodel 16.2.89. 12 00.00.30 0 H 955 00.04.86 55 30 21 15.07.88 Yes HI* Polfworker Autoclave Heenangioearkaa. Also Developed Cho langioaaroona. Friedei letters 23.12.8b, 15.11.89 and Feodel 16.2.89 13 00.00.17 8 a 1963 19.08.B1 67 30 21 25.03.85 Yes High Autoclave Cleaner,, Cfasnistrj Uorfcer -s U0.00.34 4 4 1956 11.05.B5 51 29 16 17.09.86 Yes Hlgfa Shift > Leader * 2 UO.QO.24 4 4 I960 18.2.73 49 5 4 16.10.84 Ye* High Autoclave o Cleaner to w Letter free Dr Friedei 15.11.89 Letter fro* Or friedei 15.11.89 1975 disease of li votr parencti|w; at Last kit. Letter fn* Dr Friedei 15.J1.89 OEUANY Sheet ft l I \2 LIVES Angiosarcoaa Coses { Review Uale: I Jan 19%) I I I-------- 1----------- 1-------------1-------------1-------- |3 4 j*| G j / j a | 9 ------- !---------- 1---------- 1-------------1-------- JO | II | 12 | IJ | J4 15 lb comm jus reference m HUE at I UTE or I ( FIRST VC | UK(V | IGEIT j YEARS Of IHIT1ALS SIMM CWANY]FACTORY| EXPOSURE j DIAGNOSIS | DIAGNOSIS j EXPOSURE TO 111 | 1 DIAGNOSIS I YEARS OF | DATEOf EXPOSURE j DEATH j I H1SIO j | | LOGICAL | ESTIMATED j | CONFIM-j EXPOSURE | OCCUPATION j AT1CN j LEVEL j OTHER CAREER HIGHLIGHTS other cdscirrs 36 oo.oo.is 4 4 19S3 19.01.76 57 23 23 14.02.66 Yes High Autoclave Marker Letter fron Dr FriedeJ 15.11.69 and infurnatiun Iron Dr Tenkboff Dec 69 37 oa.aa.2S 4 4 1969 09.08.85 59 16 6 OS. 09.86 Yes Laboratory Assl stent Letter free Dr FriedeJ 15.11.89 38 ao.aa.22 4 4 19S4 16.06.88 66 34 19 16.09.86 Yes Hi*i Shift leader Letter fron Dr Friedel at ibe 15.11.89 autoclaves; later on et the tflbler 39 oa.ao.42 4 4 1968 00.10.86 44 18 5 03.11.86 Yes High Autoclave Cleaner Pension frtai 19/4-84 80% Later 00 100%. Letter fron Dr fried? 1 15.11.69 and intumdUun fr Dr TenAhoff Dec 89 o P ci a ts' PtH(o0r- ch PPL H" O P c+ tor* PH* :-h o W to o Oo ppi rP* P rr w SI n 3: > o-* o to CM Page 19 CMA 0 1 0 7 2 A mu Sti--t I 1 23 axmv aw m nanus DATE Of Aim 4 conn LIVE* iogiusarcuw Caws - (Bevies [late: 1 Jan 1990} 1-------------------- 11---------------------- 1---------------------- 1 56 7 8 9 nctmi FUST VC DATE QT DIAGNOSIS AGE AT DIAGNOSIS teass or DIAGNOSIS 10 YEASS or H DATE or DtHH 1----------------------1 ----------------------------1-------------------------------- 12 13 14 15 { 16 i HISTOLOGICAL OQNFUMkTlQN ESTHATED LEVEL OCCWMIOK OHM rutn HIGHLIGHTS otm oatorrs 01 (ob nasi Wleeatan list) LG 1S.OG.34 P1MSAC Kirs Venice 00.00. GS 19.04.71 36 02 St 03 to 13.11.29 HontsdleoB Porto ao.oo.s7 13.12.72 43 14.03.20 Solrsf Farrsrs 00.01.S3 10.07.7S SS n 20.07.37 AUC 00.04.S9 00.01.61 43 OG 03 1G.OI.71 7Tes IS OG 27.12.72 Its 22 21 10.07.7S tee 21 21 30.01.81 Im High PVC Bag evtrudar i Primary luuur ay have been pericardiia. Hot bfpgenanua with other caaea. * a* Polftnrkar i-------------------------------- 1 _ __ L ** Autoclaaoer 1972-5 did a Its (1951- a variety of Gl) Gutoclaw > ** operator Including 12 jrs (1961- PTC parting. 72) ** 12 Its - 1 it - Imr cleaaed *eri High Itsswr autoclaves. operator See paper by S jcs - CHUmSQ et IGn-wnker. Kadius 20 irs lutoe lave al Red Lavoro fxsMiastd i Vol 6 (1982} little 4 irs - operator G 1 K> 555-563 alcohol. Hu Lot oilier duties] ML. ion paljser-l Istllaa. | 1 1 1 ties rawwo| 1 In saw Dept | since 197S. | ______________ 1 1 ----------------------- 1---------------------------- OS G Omula 19.03,37 PUSAC Mira QO.OO.G7 07.03.83 4G | 16 |S 06.04.03 lee lkdlie-7 Beg extruder | S PagltaJunga Venice 11 High 1967-1975 | telei of 11 1 Gowerciel | | 2 hug 1983 11 1Dept 1976- j | _____________ 11 l1 1 1981 | | ______________ :___ 1______________ 1_______________ 1__________________ S ubject to P ro te c tiv e Order in Foss v. Conoco, In c . , Do. 90-4337 14th J u d ic ia l D is tric t Court C alcasieu P a ris h , Louisiana See Italian Hod di Lavoro fcS p44S, 1974. Further details is letter [roe Dr Monleeaeo of URC ae tprll let 1982. * tJeo see Helton! sod BuodineUa in Beta Onruloglca ttol 1 1980 pages 15 - 49. sSd 2 or, , Cj. ^ O _ c+ Pdfp 20 nu.v Shut 2 1 courmi us imma HO 06 I3 DUE OF OOTULS ION a 11.06.36 LlVCft Angiosaroana Cases - (Review Dele: i Jan 1990} 4 canon s|------------------ I------------------ -- ---------------- 1------------------ 6 7 8 9 10 | 11 12 13 H ums or 1t 1 FUST VC inn or UE IT UFG68RE was or] date of HISTOtOGICAL estimated focnbf DIIOIOGIS 0UOBG1S W Ejmsttcj DUm covownoa occvmoa ouansis 1 lUVEL i 15 j 16 --------------------11------------------------------------------------------------------------- l <mn CI8E6B | j OIHEB COMBS HIGNLIOMIsj r1 -------------------- ----------------------------------------------------------------------- 1 Montedison tato 01.10.60 06.11.86 Mo 49 25 25 12.02,4b Fes Hi* FVC 1960-71 mil facture Nediia 11 jeers as | Letters Iras Dr ChLozsim, Venice, j 22.09.81 end 11.01.08 1 1971-74 Autoclave 1 Um 1975-85 cleaner 1960-71. 14 fears la Control 1 1 | 1 Roan 1 1971-05 1 1 11.01.8607 u 09.01.16 fephla Terni 1968 60 28 22 06.04.as Fw 1958-74 Maintained HI* VC Kecfciner] (act operating or cleaning autoclaves) 1974-80 VC levels Until* reduced free 1973/74 Infomatiao feta La Medicine del lavoro, ltal|, Vol 79 Mo.1 Jaa-Feb S6, and Dr fteoelta, LaiOwe. 1 CMA t 14th J u d ic ia l D is tric t C ourt C alcasieu P a rish , Louisiana 1 O ______ 1 ______ 1 ______ ______ 1 ______ i UO-I1 O \J M U  Pane ^ LIVER Rngiosarcoaa Cases - (Revlev Date: 1 Jan 1990) 1 coumv urn reference m ----------------- 1----------------------, l s2 3 4 tarn at om or minus uni omm nemo* -------------------- 1---------------------- --------------------- 1-------------------------- ------------------- 1------------------1---------------------------- l lt 0 78 n9 10 | 12 1 It ti l1 FIRST VC DATE Of AGE AT TEARS OF orTEARS om ar |histoxciou. | 1 i 13 j | i 1 estdhed | " 14 s I1 exposure DIAGNOSIS DIAGNOSIS EffQSKI TO diagnosis EttCHRE 1 1 1 exposure | ocotetk* LEVEL j 1t i 15 16 OTHEV CABm HIGHLIGHTS OTHER CGHBRS 1t 1l 1l ao.03.so01 IN 23.12.IS enk Jtorofa 21.12.71 56 22 21 04.01.72 | Tes High |Farawa 6 Confined bj rdra 1 |Autoclave (Dr Ails- iI Ifffemisor lEvusea of NH. Sd H-* s g* 4^ " O- ct & ^ o' o * ft o c+ o P* H* O 5o o o taj H* P 2 " 4 O H- l*--sll fcl to tr CJ H* U1 c+ x o <+ H- <-3 ir< o P 4 l J* O r+ " <3 4 M > f* O VD CL O O -O it i 4 ct+ C3 4* CJ J * >n2 O O Nl M \J I 1 1 | I t1 1 \\ 11 i| 1| 11 | j 1 1 1 1 1 l _____________ i I I 1 l l l I I tii l I l I t l l i I I i j 1 1 i i i i 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 t 1 1 1 it II ii i| I1 11 ti Ii |f ii i |At APK Htg of t |9 June 1978 i Jlfc* P RwoywTf i j stated that AH i |had teeo a i |water of a {start-up tew. i 6jvCH PVC wre i |aade in saw i Hie(building. i e|VCX was mmi 11 [fraa acetylene ll--------------- iI iI iI il il il iI iI iI iI i| ] 1i iI iI iI J1 --------------------------- 1 LIVER tagioaaarcMa Case* * (Revisa Date: 1 Jan 1990) * Page .:3 o 3: > ta sio 10 00 SP11I ' CONFIDENTIAL S ubject to P ro te c tiv e Crder in Boss v . Conoco, In c ,, Po. 90-4QJ7 14th J u d ic ia l D is tric t Court C alcasieu P arish,. Louisiana LIVER Angioearccaa Cases * (toview Date: 1 Jan 1990} * oounirt up m 1 -- -- --------------------1 --------------------1-------------------- 1 1 1 1--------------------------- 2 1 4 s6 7|8 9 10 II 12 _____________ 1_____________ unws un or sitnt mm rtCTGOI FIRST VC WQSUtt DATE OF DIAGNOSIS AGE AT DIAGNOSIS TEARS OF EXPOSURE TO DIAGNOSIS TEARS OF DATE OF DEATH HISTOLOGICAL cmumtum a 01 w 23.06.27 fn--inrd Sunknll 14*06.51 30.10.70 43 19 IS 20.10.70 Yes 02 BL 2T.ll.il 00.01.4S 00.00.72* 61 27 27 16.00.72 Tea I1 13 14 | IS | 16 ------------------------1---------------------------- J----------------------------- ESTIMATED EXPOSURE LEVEL I occunnao j other cikeer j HlGHLlGtflS I j j OTHER comEirrs ------------------------ 1-----------------------------1-----------------------------11 Polfworter | | 1------------------------- I(---------------------------- High VCN jit Sjoeiin's prodictiaa |letter of |2S Harcb 1976 |coolires BL 01 a 04 8L 10.06.10 16.11.14 Suntonll OO.OS.47 10.01.76 Suadarall 00.00.46 12.05.77 6S 62 29 21 19.01.76 tea 11 11 12.05.77 Tea W m3 < o oo H- <+ Mo O o rt 2* oCl o Q *X> OOcCD+ irl- H<1* CD ir> o o Oo 1 1 M> 1 r* _____J-- ____________ ____________1____________1 OS J- |12.0J.I9 j (ami jsindmll 11.OS.64 t 22.11.00 | 61 1 1 1 1t _______________ I 16 | 1 11 16 122.11.80 | 11 W| *1 | 1 \ 1 11 11 III III 11 1 1 11 III till ----------------------- 1----------------- 1----------------11 1 i1 11 I ____________1_____________1_____________ ----------------------- 1------------------ 11 Tea | worker who mu |heavilf |expo*ed, Iprohatlf even Jaore so than |a aoraal (reactor (cleaner Ugh ----------------------- 1-------------------------- PolfworAer i 194L-1956 ------------------------1-------------------------|in first 12 pOlfBBTisatian tarter (12 jra) & 1958- |yra of |eaflo|Bent bad jbeeo beavllj jexpoeed. In 1977 foresee {19 |rs) J1974, liver lataoraelitf 1 (and necrosis (dieynaod. {Data coofined 1 jin Dr D Bfren 1 jletter 18*6.77 1 jto CEFIC 1 High - 11964-1970 b leva Iceotriruge Lue - I<jpera(ar 10 *eva ||970-1900 1----------------------1--------------------------| jitter ut I |2od Muv 1981 | |tr j |l)rOvjd B,reu 1 |drier | I luferaluc | --------------------11| | 1 CO * "J In his letter of 1*1 April 1982, Dr Nuntesaoo of IARC says Sweden's National Board of OS Health gives 20-02-70 as dale of diapueis for Case 01 and 15-05-72 for <>r 02  Page stesi \ L1MEA Angiosarcuea Cases - (Review bale: i Jan 1940) COUNTRY , ran HO mw at om of UOTIiLS I1RTH I 8I 10 12 13 nciDRi FIRST VC j HIE Of EXM6URE j UltOKSIS I AGE AT j YEARS OF DIAOOSIS f EXPOSURE TO DIAGNOSIS YEARS OF DATE OF j HISTOLOGICAL DEATH | CONFIRMATION ESTIMATED EXPOSURE LEVEL OCCUPATION UtUUt CAREER HIGHLIGHTS UTWit CUffRJTS 01 1*J i 20.M.01 | ICI I I I I I HUUm**! 04.04.44 01.12.72 (Fa> 6 Collier 21.12.72) n 22 |03.12.72 (Fob t Collier W( 21,12-72) 102) 03 l02.0t.17 Ifarrr + I 00.02.66 | 00.12.74 3.5 24. 12.74 `"Ih!?? O T * S' oo 2 <o+ 0 te* a j-*- C/J Hc^+* I C) cO+ ? o OO 10 O -i1 J Ii cr n fcj M 11 t-3 i-1 fJSt 21.06.20 o > O vl o 18Hilltaouwl 26.04.54 00.06.79 59 25 12.10.79 I 500 | 1944-7 VOt 1947-8 Drier 1948-81 Autoclave i operator mi-bt> Drier Lee and Harr? leanest 29-06-M pages 13X6-8 Dubious fabrication case High Exposure Halted to |2.66 - S.fet bigfa 1954-5 J Pre-war f isb Bagging |packer Plant 11939-45 araf 1955-6 | vehicle Drier Plant |--inteoance 1956-8 Autoclave |1945-54 (flab pecker worker 1958-61 Chargeband Drier Plant 1961-/2 Foram C 2/3 Plant C O N F ID E N T IA L Subject to P ro te c tiv e O rder In IBoss v. C onoco, n c . , *fo. CO-4 3 3 7 14th J u d ic ia l D is t r ic t C ourt Calcasieu P a ris h , L o u is ia n a Pegr \ countv AMD REFERENCE NO 2 NAME 08 INITIALS - Sheet l DATE OP birth 30.Q3.H DA 1931 07 20.04.20 06.06.24 o 3: > o v w Barry Burr tarry tarry FIRST VC EXFUSURE l.lhiER Roj* nsama Cases - {Review Dale; l .Ian ISSO) 7 10 II GATE OF AGE AT TEARS OF YEARS OP DATE OF DIAGNOSIS DIAGNOSIS EXPOSURE TO EXPOSURE DEATH DIAGNOSIS 12 HISTOLOGICAL CONFIRMATION 11 T ESTIMATED | 14 EXPOSURE | OCCUPATION LEVEL j JS OTHER CAREER HiGHiJGirrs OTHER CiMttJHTS AS IV.11.79 09.0I.W 46/9 16 12 09.01.60 1963 00.00.8Q 6.2 |l9M-57 j |polyc leaner f j1952-55 j |PU( Un*f (informal tun | tvttt fiim jLdtK |l955-6U J j [ Polyfloor | |l960-M Ml jctiargehaod j ism-m | 1 J j ]Chargrog (operator | J |i)r P M Satlh [and Dr II II J jUif Jiaas 1 l 1 1 1 l (19W-/2 | Drier j j l l [operator | l il--------------------- 1i------------ ----------------j------------------------ \* K- | | Fur liter |Poly Floor j | informal ion [iterator 1`j yra | j |Greaser 00 | Mi Flour j |l9H9 trim \tK e n Smith jand DrDN J (UiJ liams -J-----------------------1----------- --------------- i . jPoijc tease j1961-5 Iftecovery f 1965-1971 Kurther inform al too 1909 fro* Or PH Smith A Or DM J UijJ tam 19.09.60 27.11.61 57 26.12.11 1960-1966 WO (pi 1966-1974 200 ppm 1960-61 (1936-1946 (Further Autoclave [Motor Mec6anic| informal ion operator 11946-1960 11909 from 1951-1957 jchargeaan (autoclave (Operator 00 [Acetylene [Production jDr P H Saltfe jd Ik- 0 N J juillioH [building j1967-1974 (shift Istfienriuur [plant 1 1 1 1 1 1 1 [autoclave 1 1 Jbui Iding * i 1 (Never i 1 (cleaned 1 1Jaulorlaves 1(hot supervisor s| 1 1 1 t I<<1> enldi tedj entering 1 1 1 oulitc laves 1 1 tu inspecl l 1 lu. l 1 t LK Sheet 3 1 chunim ras HO MINE US | DATE OF INITIALS BIRTH EIGP 07.0S.25 10 GJT 04.04.47 11 o 0} ON O P M 0O3 o09 H* oo CD C H!2} hd ^ OH P OH H* i_. <+ fcl icfir 5 o E3 e+ a ` H* tr1 o rt c~: o i. oc o `1D GU> n 2 O M W W UB.Cb.38 + (24.01.3/ I ECI 1.1 VtJt Angiosarcuaa Cases - (Revive Dale: 1 Jan 1990) factory HAST VC DATE OE DIAGNOSIS AGE AT DIAGNOSIS TEARS Ot` EXPOSURE TO DIAGNOSIS TEARS OP EVOSUiE DATE OF DEATH 12 HISTOLOGICAL CtRFJRHITlQN LI I 14 I ---------- 1--------------------------- {------------------------ ESTIMATED I I EXPOSURE I OCCUPATION | OTHER CAREER I OTHER j CttfMJfTS LEVEL | J HlGHLJUfrS j SB 33 29larq IS.02.50 02.Gi.ft3 24.02.63 Yes Nediia Iftilfworker \2 fears on | i (Acrylonitrile J t 1Resin Plant. | |A Iso prior to j 11950. 4 fears| |MT | |aiatenance. | |3 fears autor \ Jcar paiotsbup. | |2 years in | (Graving Dock. | H---------------- h torn 27.04.66 01 05 04 37 10 4.2 16.05.64 Yes High - IJ |Polfcleaser jfcary goods jliifunatiua aonths (50D|l966-67. |vehicle dr iver (given in pf). Loe-|Spray-drier (until final (letter 18 Months ( > IfcMUlB ' (bagger I%7-|il)nes. |60. I (Hluudma |]ft.Ob.84 fr<Ji (Dr D H J (Uiltiaaa 21 aontfts (stripper (200 nmi (operator I I |l966-70. I Barrf 19.12.65 02.06.65 57 HiIJhouse 16.09.57 16 02.06.65 26 06.12.65 Yes High jpolyc leaner f (Letter of 1965 -69 | ms-88. I 104.08.89 Hed 69-79 (Service ( |Dr Paul Sauth Luu 79-82 (operator |88-69. ) j (and letter ut jtH.0fc.8S |Full ( |t>r PHD Evans |Operator J (Oesophageal |89-79. | (haeaorrttage |Leading Hand| j79-82. j |<Jue to |iKSuphageal 11 (varices due to * i1 (Any kusarcxNhi 1 ----------------------1 Lou 1957-Vl|spare aao, 1 (of Liver |--------------------------- 11----------------------------| (Let ter High 59-/4 (bagging ( |2b.Ofc.8`. Um /4-ftS [l k,t ||9S7-S9. J j |l>i f 1 Iji.1 |Aulocla*e ( 1 ({Jpcral or | I'ivj as J j 1 1 SPMOOO OtHt)* 4^ cl* cr Ch pCii H0* hJ P M* P ** wcr a(0-1 e+ HcO+* a o th c+ Page UK - Sheet 4 CQUMICt I 13 ii -h--(- II i |mk at | djlte ar| jmritLsI tum am I + IM 02.03.46 BP I.IVbJt Angiosarcoma Coses - (Review Date: J Januarf J99G) T + I FIRST VC |UATS OF FACTORY wn I960 Jm 66 i ^ --1---------------- 19 10 11 i1 i\ |mj it YEARS OF jttFOSUIE YEUtS or DATE OF |0ItGll0SIS|l0 EXPOSURE DEATH |0IAGKS1S 1 1 37 1 ia 3 02.06.66 ! i i 1 12 H1ST0- -- 1 13 t H 1B 1 ---- 1 LOGICAL |tSTlMTCD| CONFIHR-1 EXPOSURE j OCCUP1TJ08 onKB CAREER oraeg cunarrs AT106 LEVEL 1 HIGH.IGHTS f1----------------------------- Yes High |po Ifcleaner Moved to Renamed well, working 11968-69 Acrylonitrile actively, until Jan 1986 Low |Ceotral Plant until [Depot left BP 1963. 11969-70 Manager of 1C 6 1 High Polyfloor j 1970-1971 SS Ltd at Cardiff Airport j 1963-66 14 IS.00.4 IS BCF 23.06.2 Karri 07.07.tt 27.06.87 4S 1956 I960 jj 66 ii u i 32 16 Ql.12.66 Yes IU ratttt PoIfcleaner High 1966-67 10 fears Pol f floor coastant worker at tines Nadlua between but oa 1968-1982 loter- i Htaot 1 lota Letters fran Or Ul) Evans, Pathologist, Penarth, Hales and Dr UU UHIUm, 6P, Barry 01.05.66 Yea 9 jean S fears Miia 2 jean Low Pol) cleaner & Operator Exposure Blow 6 Recovery Operator Utllltf intermittent CperaLot Inforaatian froi Dr 0 6 J UiliiaMS, BP, and 11 Smith, Pathologist I960. 16 O O S2j M tJ 2S.0S.2 IC1 Hillbouse 1963 1988 66 2S 12 12.11.88 Ves 1 ?ear ) Packer 1 Lot ) t |9 fears) High ) Autoclave J2 |HTl) Operator Lott ) M.01.J1 ici Hiilhouse 08.04.63 1969 SB 26 25 17.09.89 Yes 1963-63 Packer >-3 M Low 2 Months 1963-74 ) lT High ) Autoclave (II years)) Operator 1974-86 I ) 2S fears Low > (l fears)) CMA 010733 ___________ 1___________________ and Or K 1 Lee, Blackpool > Pafe USA Sheet 1 23 courm aw lEFCMMCe NO tarn on INITIALS turn or NINTH 01 Carl 17.10,23 Porta 01 10.00.11 03 &kwrd 2S.06.1S Olnuldiie 4 cueIKY ors we NfG JJVEfl Angiosarccae Cases - (Review Date: 1 Jan 1990) UK syslea of dates DAY - MONTH - YEAR --------------------11----------------------1 56 7 8 factory FIRST VC UTE or DIAGNOSIS ACE AT DIAGNOSIS Uulsvllla . 12.00 03.03.73 49 Irtlllville 16.11.66 00.06.70 37 Uails*111* 20.11.06 19.12.71 60 9 TEARS Or EXPOSURE TO DIAGNOSIS 24 10 20 10 TEARS Or 1--------------------------- 1 --------------------- 1------------------------ 1--------------------------- 1------------------------------ 11 12 11 | 14 | IS | 16 DATE Of HISTOLOGICAL 11___________________________ 1 1 1---------------------------- 1----------------------------- ESTIMATED | | OTHER j OTHER EXPOSURE | DEATH coNriMunoN EXPOSURE LEVEL | OCCUPATION I | 1 career HIGHLIGHTS j j 11 concurs History given (dolling Slone :ln Inna Is BY (krt 21 01.01.71 Yea Pot Cleaner (Block Jaan 1974| p 53 *Ck0 SCIENCES (del 1 NY dead idol 129 (1979)jof Sc S|np page 190 in j 1974 Pager bj |llso Block B B Coltine of|Jme 1.7.74 ' OSHk jp SI 13 27.09.71 (uoaa aara 20.09.71) 20 19.12.73 Taa Tea Pot Cleaner J (Cl Blade) | j 1 |kef 1 jllso Block jjMt 1.7.70 1 Ip si 11 i Pot Cleeaer |Uxiliile Ref 1 (Cl Block) j Courier Also Block |Journal (02-09-80 15.01.20 IK Louli- 06.07.62 10.00.67 43 15 15 07.01.60 lea vllU Pot Clamor (Cf Block) Ref 1 A1*ej Block td a c+ 0& S C-C Hd>* P p pHO*i hPd M* P 4H01* tJ* tHws* c+ o C0f)t 01 PO' C-M <3 m o oc+ o p oo o Oc+ hd O o i; o I- . Mp Q <+ i t COD l rt- i o p ac+ O a> o HP* P O P OO n> n P rt CD 0-45 p (ft 2S.01.12 BPS Louis* 10.06.40 09.00.60 62 20 20 09.00.60 Yaa Pot Cleaner Ref 1 (ft Bar 21.11.20 vllle Louis* 17.01.62 00.02.70 ______________ _________________1 05 | 12 12 24.07.76 Yaa (Cf Block) US klr force Also Block 1-----------------------------jdef 1 * halt in *111* 1 |Louisville Jonaa? t Pot Cleaner |Tines 23.7.75 1 (Cl Block) (Retired tpril 1 (1974 07 Charles 01.06.22 ucc S Chari** 27.0B. 44 00.00.u 1 1 1 45 | 24 17 23.03.48 Tea |klso Bluck i i i-------------------------1 1 |Rer 1 T Saart stoo I _____________ 1 ___________ ___________ ]_____________ 1 ______________ l________________ J i I-------------1 11 1 08 |(ft.1ft. 70 Goodyear (Niagara | 07.10.06 00.00.61 1 01 1 IS I IS 29.08.61 i Yea j 1 1 i | 11 ____________________ 1 i i-------------------------- | (del t 1 n1 51 > _i___________ 11 11 11 11 11 1 I1 !! 1 1 --------------------- 1-----------------------1--------------------------------------------- 1J____________ - III 1 III 1 III 1 ,111_______________________ 1 o 0 vl 01 -o Cft o p a o Hpto* CD J3* <<SJ ^ O ooyo cf ct o d P>Hi* Cfl oo *xf lo-i c*` 13* O S. **~ H<- ?o O tO Oj o o CD - i rt og ^^ Page USA - Sfaset 2 -- ------------------1 ----------------------1 LIVES Angiosarcoma Cases - (Review Date: 1 Jan 19%) -------------------- 1 -- --------------------------1-------------------1------------------ 11 6, 2 J 4 5 7a 9 | 10 | U 11 couvm UD urom > aw on OTTULS DATE OF SUN comm ncnw FIRST VC DATE OF DIAGNOSIS AGE AT DIAGNOSIS TEARS OF EXPOSURE TO DIAGNOSIS TEARS OF EXPOSURE Dm OF DEATH 09 Upad OS.11.31 KQ Umla- 2t.tK.45 01.01.74 43 29 24 11.03.75 GatUe- iii* ringar? IQ 16.06.13 Goodywar Niagara 12.0t.Sl 00.Q5.bA 55 17 17 IQ.05.60 n 27.05.09 Goody.if lagan 14. 10.46 00.03.70 61 23 23 16.03.70 1' n.u.ia so12 Francis A Nnahu Fottatowa 13.07.49 02. OS.09 20 19 02.05.69 fa UK system of dates day - mm - YEAS 1 1 1 i 12 13 | 14 1 HISTOLOGICAL oavutunaH ESTIMATED { EXPOSURE j OCCUPATION LEVEL | ______________ ________________ 1 1 Tea 2000 mm | 15 OTHER CMEER H1GW.10RS | 11 | j j lb OTHER COMBfTS 1 |tef I baa ' | twang figures | [re first l [exposure, f [Louisville 1 |Ti-ea | (29.10.74, | J12.3.75, j j10.3.76 |----------------- 1 Tea 1 |Aef 1 11 Tea 1 Ref 1 11 6 *Tea High 10 yra 10 yrs as [utility Oaf 1 letter |reactor op. Service op. of 26 April (not cloaner[Bagger 1978 frcM - separate [Dryer op. Rugae11 8 Park crear claaned|Stripping ap. to J T Seawall autoclaves) |3 yrs prior of NCI [service In [tyre plant 13 n 3 ^ (Ml *1 -1 zi -J \ -4 > <!!>> Richard Eduard 01.12.21 Claodaaia UCC r> K > O) _________ o1 Vi I Vi 11* ____1 S Cbarle- 11.12.42 OO.OS.74 1 52 j 32 i |26 07.04.74 Yaa 2000 pfM i | i |cbarleston too 1 1 1 1 1 11 || 11 11 11 lOaill Ha*l |21.7.75 _____--_____________1 l t 1 Never diag 1 11 nosed as ang- 1 11 1 11 liver. Inform 1 11 ation given in t 11 letter 22 Nay 1 11 1904 fns 1 _____________ ii 1 1 1---------- 11 ii 11 ii 11 ii II ii---------------------------------------------------- 11 1 11 1 J A Salg. _________________ 1 11 1 1 1t i Accountant ; 1 III ASL - No evi 1 III dence of VtJI 1 III 1---------------------------------------------- 111 exposure. Page 3<? USA - Sheet i LIVES ingiosarcoaa Cases - (Review Dale: I Jan 1990) UK Sjstea of dates DAY - HUffTH - YEAR ------------------------- 1 1.1* ------------------1-----------------------1----------------- 3 I4 15 ________________ 1_____________ ____________1_______________1___________ 1 1 COMRH UD | IMP CR hie or REFEUNCE | IHIT10LS IHW CGNPIHV MCNH HO | ________________ 1_____________ ns16 |J- 04.11.77 Louie- Howard U1 1 6|7 1 FIRST VC EXP06QM DATE OF DIAGNOSIS 06.09.5Q 00.00.69 ----------------------1------------------------- 1--------------------1------------------1--------------------------- 1 1 I 8 | 9 | 10 | 11 | 12 13 | 14 | lb | 16 1111 1 | 11 --------------------- 1------------------------ 1---------------------------- 1---------------------------- 11 i 1f l AGE AT | YEARS OF | YEARS OF DIAGNOSIS j EXPOSURE TO j EXPOSURE OkTE GT | KrSTOLOGICIL kmh j covuatnoo ESTDUTED | | exposurej occwanoH j OTHER cireer | OTHER | concurs | DU9QS1S j J LEVEL 1 1 HIGHLIGHTS | 11i I1 1 -- ----------------------- 1-------------------------- 1------------------------------ 41 19 04 27.01.69 1 Yea 1991-4 VCH |Krua J9S4 |t^>le 4 10 polfar- {onwards in {ttojcoer 1 last ion |Araf and other{Testlaoof to |service. JtlS Senate |46-90 Aiaf {Confined in 1 | |N N Johnson { jltr O7.Ott.70 Loule- Yea areIT PHnaha 06.05.11 *11U 21.06.5S Il.IO.M 43 19 19 16.10.00 oc 11.10.74 11 ------------------------1---------------------------- -- 1 l |Dr N N Johnson but BO l !letter of post-aortea 16.10.60 I 24.2.01 con l fined death 1 6 fears after l diagnosis i U Charlie 22.04.28 K Arthur 8woi Lake IS.09.64 00.00.75 46 21 u 02.11.75 fat 13 fre Navi autocteener 0 rrt oc Estol Tyre Store plasticiser 6 Carboset operation Confined in H M Johnson Ur 07.0tt.7S Also Rolling Stuae aug. 15.01.76 19 Virgil 00.00. IS ucc CHrUtia S Cherle- 00.00.41 etou 19.06.75 , 60 30 n Chester Hinkle ________________ _____ 1 jll.08.17 1 1 |02.09.09 j Goodfear UCC 1 1 1 _______ ____________ 1 Niagere | 00.00.S5 ___________ 1____________ 1 S Charle-I 00.12.46 slOQ j 30.01.76 Larlr 77 \ 1 1 1 ___________ 1_____________ i SB 67 32 12 06.04.76 tea 2000 na 1 _--_--_-_--_-_--_-_--_-_--_-_--_-i1 1 1 1 21 16 |30.01.76 Vee 1 1i --------------------- 1 l1 30 22 |02.G1.77 Yes 1 11 11 11 11 1 1 ----------------------------1-----------------------------i luiUleeeport |Sun Gazette |21 June 1975 | Char testae joailT Hail |21.7.75 ----------------------------1i----------------------------- INOISH letter jut 25.10.79 ------------- :------------- 11----------------------------1 (28 jrs el t)i |UCC al SC |Relired |Hews release (21.2.77 __________________ 1___________________ C O N F ID E N T IA L S ubject to P ro te c tiv e O rr^r Boss v . Conoco, In c , No 90*4337 14th J u d ic ia l D is tric t Court C alcasieu P a ris h , Louisiana CHA 010736 OSA - Sheet 4 LIVES loglourow Cases - (Review Date: 1 Jan 1990) UK sjsln of dales DM - mmi - TEAR -- ------------------1 ----------------------1r--------------------- 1 ---- ii 1 2 i 4 5t 7 a 9 10 H 12 n 14 | 19 | lb 11 oouvnv in m 22 n M g* p? ]H M S -i t*' fi> Jb4 o <+r . & g o c; OO h[J ^ |-i !1 J 4 ` O1 h- ,, u-, `r; M JT 3 u' ' 1 1 i 7 t* > ,, <0 - 1 & ^ ? ok V oo w '=> 2 '1 0^ Oj J om or mruu um -- noon POST VC un op oiaotcis AGE AT 0USHD61S TEAKS OF DIAGNOSIS omTEAKS Of or oun 02.10.21 Loula- U.07.47 00.01.H S2 29 20 04.12.7b *Ula H 00.00.23 Gnat FltdOurg 00.09.M 00.04.73 50 13 14 0b.04.73 Aaarlcaa Cheat cal Caw Dele ed 1990 bf 1 laawtt: Hot asgioi n, tut confirmed C iioQlna>fnf -> O w \J Beat*rai free reg ster conf raed io R 1 ' ______________ ____________ __________ it S' i i i i arofi Oonaber 1900 1 1 ______________ 1_________________ HISTOLOGICAL oomamtim Tea Tea EST1HIED LEVEL occnranoi 1 1 1 t t 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 OTHER CAREER H1QL1GMTS OTHER oomrs Louisville Tiaas 26.1.7b said be ns the lOtb AS victia at Dells Lane of utu 8 had died b) 26.1.7b la bis Letter at lb.09.Bi Or H H Johnson cunfiras this is tbe case described bf Danoaber Taaburro k Taa in fab 1980 Aa J Medicine Vol 70 p280 R H Wheeler letter of 20/2/79 end Ruaa Kaaunski letters of 26/2/79 and yu/90 _______________ _______________ ___________________ Page 3^ LIVEJt Aufiosaruaa Cases - (Review Date: 1 Jao J99U) UK systeei of dates - DAY - tUCTH- YEAR USA - Sheet 5 t 2 3 4 56 7 8 1--------------------9 10 It 12 13 14 1*1 16 OQUmtV AH) UfEUKX MO mm or OOTIALS DtK OF tun comm FACTORY HAST VC EXPOSURE Din or DUBU61S AGE AT DIAGNOSIS YEARS OF EXPOSURE TO D1AGN06IS YEARS Of DATE Of DEATH HISTOLOGICAL oomsamnm ESTIMATED EXPOSURE LEVEL occurATIOR OTHER CAREER HIGHLIGHTS | OTHER CUMKHTS 26 John Berry 07.07.21 BTC Louis11U 01.10.47 00.00.77 (tS to 2 yenra after death) 52 IteU) 28 (death) 18 11.02.76 ' tea Eapoeed in Various jobs sane degree in PVC to 22 Iplants fna IdiaafcaJs cold roce to |but nein [esposure ipaste recover! to l* to tat, |PC charging IpmUfalt operator to |bi(* [paste charging. |lll August 1965. Terminated Ic^lopaeot Jan 1966 R Kaminski letter of 26/2/79 and Prof. Tenhurro letter of 9/1/79 27 J L 11.05.18 ucc famst S Cherle- 01.07.41 etos 10.11.78 82 17 20 25.11.78 (KIQSN 27 and C OtUr fell 75) Yea Ugh Operator to 10.10.78 Exposure in R H Iteeier bulk and Ur of 4 Jao diapersluo PtC 1979 and aaufactuee Char testae Dei IT Mali 30.11.78 and R tMinahl 2b/2/79 C O ^ F I J E j I I A.T, S ubject to P rc te c tiv T o r'd ^ r In Boss y . Conoco, In c ., I'o. 90--1327 14th J u d ic ia l D is tric t Court C alcasieu P a rish , lo u io io ^ a 28 11.04.17 ucc S Charle 00.08.44 03.11.78 81 14 11 01.11.78 tee ston I a*-*"*** letter of 6/4/79 29 12.10.07 ucc S Our le 00.06.42 00.03.80 72 38 18 01.01.80 tea sion 1 R `n**r > Letters of 1 19th June i960 fa 5th Nov 1980 30 M _________ 1 -- 22.0l.Zt jFiaaiagtai 11.06.64 10.12.80 68 17 15 10.12.80 Yes 6 - Unfcpmei ftaioteoaoce rtwirkla i 1 6 - Hiniakl Mechanic j i 11 1 fa fis j 5i 1 Elsewhere | t >i 11 1 1 i K* j 1 1 Hoi ler house | 1 1 Oi 11 1 1 1 Operator J 1 S VI ________ 1 i i________ 1________ 1__________1_______ 1______ 1__________ ________ 1S frs j __________ l W CO t Page SO Sheet 6 --------- 1-- OOUHlltY J ICU ao 31 um of JHfTULS sum jQ6.ll.23 UCC 32 |C H Giromj 22-02-08 sO PMOfa 0H3- CD M t+r 5MOd w^ <* o o 3 o w a> * ocf <O+ o oh .1 *faTl H ] o 3: > l o6* 11i11 oNl W tor* po OKO U .,i->li k J +i 4" 33 Is Fergim*|aa-10-27 FT | I I I j___ i___ i LIVES Angiosarcoma Cases - (Review tote: 1 Jan 1990) 10 I U f IK system of dates day - mm - YUS 12 13 14 FACTORY FUST VC |S Charla-1 12.00.46 ten UTS OF DUCKSIS 01.00.61 I6E ST OUOU61S 57 TEARS OF EffQSStt ID diagnosis am orfuss of ( j histological j estimated UFOGBU I OUTU | OOWtHUTlOB j EXFOSWE LEVEL OCCUPATION OTHER CAAEEB HiOHLlOtltS j DIME* COKTTS --------------------------- 1----------------------------- 13 02.04. 82 Yes Higb (But Owlnil Fran 1959 to (Or Decay not aa high Otnrator in 1976 Aliphatic) letter aa reactor charge Chemicals j 16.10.81 and clear reactor operator and |S M Mbeeler would from July 1976J letter of euparianae) to date |9.11.81. Wurkad aa Foreman {Also Dr Daoey (labourer Aliphatic | letter of fra Ctrl cal |07.01.A1 re Tim 1911 Operation (date of death. to Her 1946 i and a>7 I i have i cleaned reactors in that Use t i 1 Springfield 15-10-51 00-07-79 71 Louisville 09-09-54 i i___ i___ i i 14 17-05-80 An autopsy The death 1940-1951 (information (in PC w dona and certificate Various jabs (given in autoclave It Plata gave in polymer (letter of 24 eras) cauae of Hr Girous' earnifactare | February 1982 i death given usual BOTVU {from Dr i *a occtfWtion jutsnei |Waller C i "Angiosarcoma aa *\ettla| 1951-1964 (Barnes of i operator" jVarious jabs (Monsanto i in |in and |spriogfield to ii "chemicals |around WC (Dr A Muon of ii ii iodustry". 1autoclaves j1964-1971 (Monsanto (Europe. ti |Various I ii ii (clerical jjote in PVC I i ii (polymerisation ( ii (Jacililf/ I ii {Ret ired i 1t Jt j 28 Alive l Tee (01-QJ-/J. --------------------- 1 1954-74 jNultiple I --------------------------- 1-----------------------------(frof Tanburro iI (High |jobs |let ter of it 1975-62 j including J12 Hug 1982 i UlV (iSilf [br H H Johnson II 4 i I J___ I___ L I luperator * J_ _ _ l Polycleaner. {tetter ul 28 Feb I98J. t Page USE - Sheet 1 LIVER togiusarctraa Cases - (Review Uate: 1 Januarf 1990) UK sfslea of dates - MY - WUTTH - TEAR ------------------------ 1----------------r i 1 12 |3 | 11 11 1l 1 11 4 coumnr iw |wic oe |am or| UtmtWT | URIELSj UMH j ewin will iii -- M r Hn 29-01-34 HO ----------------- 1 i----------------- 1 i-----------------1--------------- 1-----------------1--------------- 1----------------- 1--------------------- -------------------r--------------------------------------------------------------------------- 5 |6 1 7 I 8 19 I 10 I 11 1 12 I 11 I H 15 | 16 111111111 T1 1 I 111 1 1i ----------------------------------------------------------------------- || fvEus of | j |histo- | | l riasT uc juiTE or |tsE it (exposuk jiuss ofj om or jiosicu. |fsmuno| OTHEi | fECTDH unsou jDI6GI061SjOfKM0IS|T0 |XNSIK| 0UTH ja*r[M-jilKiaU |0CC*TIMI CEOEEB 1 OTHEi CUtEOTS |j joiKwsisj j jiTioo jum. | HiGHLiemsi lull(Villi > 1955 11111111 -- i 03-11-62 77 10 M.06.61 |fu 1955-74 Ittoli ____________ 1--______________________ .. 1965 left Dr N H Johnson letter of 1 Kuv 1962, 1 Operator * |6K to 28 feta 1963 sal 9 Eugust 1984. 1 1975-62 Autoclave bacon a 1 Lou Cleaner ClargfMB. 1 1955-65 3S 09-01-12 IICC S Charle 23-07-44 16-07-63 71 19 14 16-07-63 la High fra ston 1944 to 1955. Ned fra ____________ ___________ 1955-1966 Or Uecer letter of 5 Septrafmr 19BJ. 36 7t-m-32 The Oeneraliehlehuie 11-06-56 21-00-03 50 27 27 Alive Ves Moderate 1956-56 ft W Laundrle letter of 12 Sept 1993: Tire and ( labourer spotted at nodical Aa; 1963. 1956-57 Testing nrwnnarl fcf 1963 1 prod helper I 1957-70 i operator i 1970-75 I electrician 1975-firi--it O O pa M >fs 2& iM al M <+ . e-J o ET (O' Ec H- C c a o t+ *+ O O O 4* H l"` H* W tr *M c+- o 1 . c+ < (6 IT* 4 " < go ^ O .o Ifi 1 H* 5? O i rj O O .0 5 *=i n t* w J Pafton 29.06.29 IK Louis ville 1953 06.00.64 94 31 22 8.22 *lr Calvert loa.oQ.ta 19.01.6 Product. citf 61 26.10.63 n 2 > O M II i i i I l II I iL 1. J____ IIIIl H1<K> |tol 1963-l9B2{progresaion { \ free helper | Jto senior (operator, (cleaned (reactors, (stripping a (recover! (well as (charging j jqperalur. j Inforastlan gives in letter 09.06.64 fra Dr 6 6 .kVmsfwi Thronbo cftapetua and leukopenia since 19/6. Gold treatment for arthritis 1976. Under Dr*a care about 6 auntbs before death, had passed standard pbfstcal ewani nation 3 sooths earlier. J Sarr letters of 22.10.94 and 23.01.65. i US* Steti-8 L1VEA Rngiosarcooa Cases - (Review Date: 1 January 1990) UK sfsle* of dates PAY - KJN7H - YEAR "O pM nHPCO>fl* t) tWP4Hr* oIr1 r: p Pp 0 CW 3= o1 c+ Ort- O O OOcOc4++ ** tet i=S *-3 M > ir< o o RME oa um of odtuls J taica|27.06.l8 40 * t 26.10.14 Cllnar ft Buckia) 2.02.1b(Goodiu I O 3: > o Nl 1------------------3 5 6 1------------------1 76 YEARS 06 10 11 i I 12 H1S10- 13 -- H 13 1 \ 1 L6 rusr k DATE OF AGE AT OKStt YEARS 06 DHE or L0GICU. ESTDOTED OTHER r>CNN DIAGNOSIS DIAGNOSIS TO EXPOSURE HMH cuariM- EEPGSW ocewmon jCRRECR other cumrrs DIAGNOSIS 1 11 1 ATION UVEL HIGHLIGHTS 11 1 Never in bo^ital for any chronic or Passaic 1960 Hard) 65 24 23 29.06.64 las Um 29.09.60 - |Ported scute sadicaJ probleas. Death certificate 19M l Hay 46 |before states ceuae of death cardlo-puisuasry l Vinyl |1960 arrest secondary to aogiosarcaoa of l Fabrication!with US liver. l Pint |lir Letter of 15.07.66 free John E Erl el i High Ray 66 - Irorce, of Pantasote with letter of 24.02.66 i il lug 70 |United fra Dr Auerbach, Pathologist. i I Utility |Pool i I Res in IHrers i Opurator |aad i (lac Jul 66|oksslte i - Sep 67 i Resetor ; i Operator) 1 ii Lqh Sep 70-82 it fenawr t (perater i Low 1982-83 i MU i Operator, ralandar : 1 Shop, until rvlinaot Louis- Z2.Ob.42 1967 72 45 34 03.01.67 i l ___________ ____________ 1 i 1 1 t i1 Niagara 1949 1967 72 {Falla | l 11 l 11 l 11 l 11 I 11 I 11 I 11 J_________1__________ I i 36 ____________ 27 20.06.67 I i i i I i I i fas High Cbanlcal Letter fra Dr Dietz, BFG, 1942-1974 Uorfcar 10.3.87 1942-45 U I97S-1976 iForowi |1945-76 1I Yea High ||91HS Retired Letters free Prof Ta^urro (chenicai Op/ 1977 University of Louisville, 1967 | Shift Suit/ |Poreaan, ji'VC Resin (Rge 62) and Dr C 1 Johnaun, Goodyear, 1966 |Productioo j Hediua JI96S-77 ME Plant IlLefl Plld area for 6 souths in 1965) ------------------1_____________ 1_____________________________________________________ Page >u US* Steel 9 LIVER IngioMrooM Cuu * (Review Date: 1 Januarf 1990) IK sfstea of dales div - wm - VUR 1--------- 1|---------11----------- 11---------- 1 1 2 3 4 s !6 7 --1 1---------- 11---------1I---------- 11-------------1 a9 10 1 u 1 12 13 14 1 15 16 -------- ---------------------------------------- VUKS OF HISTO ouuntf mb UK a* utc or UKUKS nanus mi 00 mm FUST VC UK OF ICC ufgoju kiss or 1 DHl or LOGICAL asmTHi OTHER ncrai 0UGW6I5 ouanais w EVOGItt 1 DOOM caaraft- cmonu OCCUMTIOR CiOMO ouausis H10M LCKL MGH.IGHTS onra oanoTs 42 ftdfcillee 02.aS.4l ana 00.04.40 00.04.02 41 14 6 09.07.62 Tea JUgfa Labourer In Pot area: pot cloaoou . regalarlf Latter fraa Ik Peter Heaill 11.04.89 43 j 01.09.21 OaoCorp LehtUnUa 14.04.SS 2s.11.ao 67 Succi (foraarlr Ohio Genual Tire! J1 26 10.01.09 Yes PVC Resin Retired LetLera free Ro| H Johnson, GenCorp Plant: 01.01 .W Ofl.05.09 and J0.0S.S9 Nigb Hainteaeoce 1.6 fMTS stun Kdl technic 2 fMT Plant Low Utdriclao 24.10 feare S ubject to P ro te c tiv e Order in Ross v . C onoco, I n c , H o. 9 0 -4 3 3 7 14th J u d ic ia l D is tric t Court C alcasieu P a rish , Louisiana o o szi *4 M fcl fed szi t-3 n o 3: > > fc- o Nl to tugoslavia LIVER ingiosarcxau Cases - (Review Hate; l Jan 1990} I 10 M I 12 count? u uraocs un of umus BIRTH COWAN! TEARS Of FIRST VC DATE OF AGE AT new DUOKSIS DIAGNOSIS TO TEARS Of EXPOSURE DIAGNOSIS HISTO- DATE Of LOGICAL ESTDIATED DEATH jcONFIRft- EXPOSURE OCCUPATION ATION LEVEL OTHER film HKM.IGKIS OTMUi CUMEVTS USSSkUU 01 02 06.04.14 Jugo Viol! Split 00.00.63 00.04.73 20 00.04.73 IS.11.31 J00 VUII Spilt O0.00.50 12.07.73 42 23 16 12.07.73 Tea* 03 21.12.3l(Jugo Split 11.01.78 45 (Vinll 04 11.06.30 Jugo Split 15.12.58(03.09.78 Vinii 03 & O P to P ,,D- < ' C-* f pO CL H* OO m oo (+ <+ O 1 o tl '<-* S 4j P 4 P J-* * 4 O 01H03* CJ h* tr-pH ,2 ^to o ] c+ w trf td !-=h t+ H* tr* 4 i " <j o P tHo* O ct* O ^ to ?o M p o o to a H ' *7 f--1 >> tr* p c+ m. o *> o t* o . *tA I I I I t t I I I I I I I I 22 22 11.01.76 + 20 18 VCK Production VCH Production SAR1C et al paper Env Health Perspective Vol 17. pp 189-192 1978 *lo his letter of 3 Oct 1978, Dr Spirtas ol RIOSH the status of Case 02 to VCK production e^tlofee. Dr Spirtas also notified a new Case 03 also a VQi production sorter. t Rose Eaninstl letter of 19 June 1980 aod [ARC letter of 1 April 1982 Page hO Incidence of ASL Cues Per Annua - By Date of Death 1995 ........................................................................... 1 6 ........................................................................... 0 7 ........................................................................... a ......................................................... 1 0 9 ........................................................................... 1960 ........................................................................... 0 0 1 ................................................................................................................................... 2 ................................................................ 1 1 3 ........................................................................... 0 4 ...................................................................................... 5 ........................................................................... 6 ................................................................ 7 ........................................................................... 2 0 0 1 8 ........................................................................... 5 9 .................................................................................... 3 1970 .................................................................................... 2 1 ........................ 3 2 .................................................................................... 5 3 ........................................................................... 8 4 ............................................................................................. 5 ........................................................................... 6 ................................................................ 7 .......................................................................... 8 ........................................................................... 9 ...................................................................... .11 .11 .8 .10 .5 19.80 No SB c+ 0 & 5 tv : P 01 o C-( o *+ ,. P S & <+ o :1 2 3 4 O l-rl C7 5 r*t- H* r^c+.1i 2o 2 W i :1 ^3 t-3 *--I `r*=- tri .......................................................................... ........................................................................... .......................................................................... .......................................................................... ...................................................................................... Ox > o vj Total .10 .3 .10 .8 .8 .11 .3 .7 .5 153 VO V Oj _j____ L TABLE 1 (Review Date - 1 Jan 1990) NOTES 1 Does not include Italian 01. 2 The 1977 total now excludes US24, Choiangiosarcoma: deleted. 3 The 1982 total now excludes G26 Alcoholic Cirrhosis: deleted. 4 Does not include the following who are still alive, so far as known: Frl5 and 28, US33 and 36. Page Distribution of ASL Cases by Country TABLE 2 (Review Date - 1 January 1990) USA 39 * * ***** N Germany 37 ***** Prance 28 ** UK 16 Canada Sw den Italy Yugoslavia 13 5 *** 6* 4 * ** ie Western Europe North America Rest of World Total Japan 3 Czechoslovakia 2 8 lgium 2 Norway 1 Spain td 1 on> S g> " S; Total 157 *< ao ^ e+ O O * Omit ItOl - atypical case of PVC bag extruder. ** Includes Frl5 and 28, US33 & 36, who are still alive, so far as known. d t-t tJ td t2j *** Includes one monomer worker. **** includes two monomer workers. **** Excludes G26 and US 24: deleted. -3 I--I P O > L-* -.n a oa .H CMA 010745 96 52 9 -- 157 Page hk Pattern of ASL Cases by Factory TABLE 3 (Review Date - 1 Jan 1990) (a) W Europe ov .is c+ o 3* s-j W <Pl p CD p- p Ma otd 0J CO 3 M a* , c_ * o o c+ o 3 rr O o p *- p o o 3 4 o tr CO o H{/I 1--l r+ 3 o O c+ l oir* H* O c+ e* : ?o P 1 4CO )- P O O 4 <Z) Pi 0 3 4 ct if* co ^ o o !s! tH w L-J > t-* NB: Of the 96 cases in W Europe, 79 have occurred in clusters at 10 factories. Of the 37 German cases, 34 have occurred in clusters at 4 factories. ASL Cases Dynamit (now Huls), Troisdorf, Germany BP, Barry, UKAtochem (formerly Chloe Chimie, formerly RP), St Fons, France Wacker, Burghausen, Germany Atoehem (formerly PCUK) Brignoud, France Kemanord, Sundsvall, Sweden ICI, Hillhouse, UK Solvay, Tavaux, France CWH/Huls, Harl, Germany Lonza, Waldshut, Germany 18 11 11 io B 5 5 5 3 3 79 There are 32 pre 1962 PVC plants in W Europe; 20 of these have had ASL cases (Ref Table 8) (fc>) H America Of the 52 cases in N America, 41 have occurred at four factories out of a total of 55 factories. In H America 41 plants have not had ASL cases. ASL Cases BFG, Louisville, US BFG, Shawinigan, Canada UCC, S Charleston, US Goodyear, Niagara Falls, US Ox > 15 12 9 _5 41 NB: There are 39 pre 1962 PVC plants in N America; 13 of these have had ASL cases (Ref Tables 9 i. 10) o vl (c) Rest of World 1> The 9 ASL cases are believed to be in one cluster of 4 and two clusters of 2 cases Page 45 W Europe IS M (M * p ^1^ a*. M E <1 o tr y m i tu H- C ffl P* *o o o p^ o H* ta C1 at &* *-* . 01 c+ 't- 2. < o ^ isj to p 2. o .o ra ** u o to Q, p 2 3 .D 3 K < *s ^ S -41 I M w tel iaj *-3 M t* o, J" Rest of World Summary n 3: > o M SI TABLE 4A (Review Date - 1 Jan 1990) ears from first Exposure to Diagnosis) Country No of Cases Total Years Averaqe Belgium 2 35 17.50 France 28 795 28.39 Germany 37 765 20.67 Italy 6 127 21.16 Norway 1 22 22.00 Spain I 25 25.00 Sweden 5 122 24.50 UK 16 376 23.50 96 2267 23.61 US 39 1002 25.69 Canada Czechoslovakia 13 52 2 314 1316 30 24.15 25.30 15.00 N America Average Japan 3 59 19.66 Yugoslavia W Europe 4 9 96 85 174 2267 21.20 19.33 23.61 Rest of World Average N America 52 1316 25.30 Rest of World __ 9 157 174 3757 19.33 23.92 Lth > 10 cases. France, USA & Canada have an average latency period above -----------------------------UOHyiDEffTlAL"------------------------------------------- ------------------------------------- Page Mt Subject to Protective OrJcr in Rosa v. Conoco, Inc. , Ho. 90-4837 14th Judicial District Court Calcasieu Parish, Louisiana (Review Date - 1 Jan 1990) DISTRIBUTION OF LATENCY PERIODS TABLE 4B r------------------------------0-9 yrs 1 Belgium Canada Czechoslovakia France Germany Italy Japan Norway Spain Sweden UK USA Yugoslavia 1 1 10-14 yrs 3 1 1 5 3 15-19 yrs 2 1 4 11 2 1 -- --1---------------------- ------------------ r --l 1 1 1 1 | | Average 20-24 yrs 25-29 yrs 30-34 yrs 35+ yrs ) | Total || Latency 52 3 10 10 6 22 2 1 |j Period 1 t|(Table 4A) l1 r _____________ 11 1 21 17.50 1 i\ i 2| 13 1 24.15 1I f 1 21 15.00 Jp J 4 6| 28 1 28.39 i 11 4 37 1 20.67 11 6 21.16 i1 3 19.66 1 1 22.00 1 1 25.00 2 21 5 24.50 5163 16 23.50 7 9 8 6 6 39 26. 10 4 4 21.20 DMA 0 1 0 7 4 8 TOTAL 2 13 35 37 37 19 14 157 24.03 a. I-iJ., He. 90-4337 --------ill District Ccurt Calcasieu Parish,, Louisiana TABLE 4C Page ' r (Review date 1 January 1990) LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE MAX POSSIBLE LATENCY PERIOD 50 49 48 47 YEAR OF FIRST EXPOSURE 1939 1940 1 2 LATENCY PERIOD (NO OF YEARS) 37,21,37,41 32,38,45,47** ARITHMETIC MEAN OF LATENCY PERIODS 298 = 37.25 8 46 3 38,14,32,42,45 4 28,11,24,20,24,34,39, 886 - 28.58 44 31 5 27,22,28,29,37 6 21,29,31,26,28,15,23, 30,35 42 7 29,24,29,28 41 8 28,24,34 9 30,26,20,38 559 - 25.41 1950 26,22,31,19,23,14,33 22 1 19,28,17,28,34,29 37 2 21*,15 36 3 25,23,22,20,31,22, 32,30,23 4 21,21,25,25,21,28**, 22,34,34 1010 - 24.04 5 22,23,24,14,19,21,27 42 27** 24,28,30,33 6 21,12,27** 32,29 32 7 19,17,15,13,16,28,30 31 8 18,18,15,17,20,29,28 9 16,21,25,27 598 - 19.29 1960 13,18,21,25,24,25 31 1 15,16,16,16,19,19,12 27 2 13,18,17,12,18,21,26 26 3 16,17,20,21,25,25,26 4 16,17,25 322 - 18.94 5 11,19,20 17 6 9,18,21 22 7 16 21 8 18,5,18,14 9 13,16 1970 1 17 2 84 * 14.00 6 VIOLA 16 3 4 TOTAL 157 CASES 3757 - 23.92 157 MALTONI GOODRICH * Aerosol can filler G 03. ** The following are still alive, so far as known FrlS and 28, US33 and 36. CMA 01074? TABLE 4p Page (Review date l January 1990) LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION ' " " ' MAX POSSIBLE LATENCY PERIOD 50 49 48 47 46 42 41 37 YEAR OF FIRST EXPOSURE 1939 1940 1 2 3 4 5 6 7 8 9 1950 1 2 LATENCY PERIODS IN WESTERN EUROPE NORTH AMERICA 37,41 47 38,45 28,44 27 21,29,31,33 29 28,34 30,26 26,22,31 19,28,34,29, 21* 21,37 32,38,45 14,32,42 11,24,20,24,34,39 22,28,29,37 26,28,15,23,30,35 24,29,28 24 20,38 19 17,28 15 ROW 23,14 36 3 25,22,32,30,23 23,31 22,20 4 21,21,25,25,34,34 21,28** 22 5 22,23,24,27**24,28 14,19,21,27,33 30 6 21,12,32,29 27** 32 7 19,17,15,13,28 30 16 31 8 18,18,29,28 15 9 16,21,25,27, 1960 13,18,21,25,25 24 1 15,16,16,16,19,19 12 27 2 13,18,17,18,21,26 12 17,20 26 3 16,17,21,25,25,26 20 4 16,25 17 5 11,19 6 9,18,21 22 7 16 20 21 8 18,5,18 14 9 13,16 VIOLA 1970 1 2 CMA 010750 MALTONI 3 TOTAL CASES 96 52 9 * Aerosol can filler G 03. ** The following are still alive, so far as known FrlS and 28, US33 and 36. i4th Calcasieu Parish) q^ Page (Review date 1 January 1990) TABLE 4E PLANT START UP DATE LATENCY PERIODS OF ASL CASES IN SPECIFIC PLANTS (10 OR MORE CASES) NO OF AVERAGE CASES LATENCY PERIOD TROISDQRF W GERMANY LOUISVILLE USA SHAWINIGAN CANADA BARRY UK ST FONS FRANCE BURGHAUSEN W GERMANY 1954 12,13,16,16,18,19,19,21,23,25,28,29,29, 5,23,16,34,18 1940? 12,14,15,19,19,20,24,27,28,28,28,29,29, 31,45 1943 11,12,14,21,22,23,24,24,26,28,42,37 (1941?) 1948 9,17,18,28,31,33,18,19,18,21,32 1939 21,28,29,37,38,27,41,34,44,34,47 1933 17,21,22,25,24,13,21,32,30,30 13 15 12 11 11 10 20.22 24.53 23.66 22.18 34.54 23.50 CMA 010751 .CONFIDENTIAL Subject to Protective Crier in Poos. v. Conoco, Ino.._'fn. 90 -4337 14th Judicial District Court Calcasieu Parish, Louisiana Page (Review date 1 January 1950) TABLE 4F LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (10 OR MORE CASES) 1 -- -- -- --1 | YEAR OF FIRST TROISDORF LOUISVILLE SHAWINIGAN BARRY i ST FONS | EXPOSURE W GERMANY USA CANADA UK FRANCE i 1939 1940 1 2 3 4 5 6 7 20 28,29,27 29,28 21 14,42 11,24 22,37 26,28 24 37,41 47 38 44 29 BURGHAUSEN W GERMANY 8 9 1950 1 2 29 24 19 15 31,33 28 28,34 3 23 31 23 25,32,30 4 21,25,34 28 34 21 S 23,28 14,19 27 22,24,30 6 12,29 32 21 7 13 17 8 9 1960 1 16,16,19,19 12 2 18 12 18 21 3 17 4 5 19 6 9,18,21 7 8 9 1970 1 2 ___________________ 5,18 16 18 1 ___________ 13 CMA 010752 COMFIDEffTIAL Subject to Protective Order in Ross v. Conoco, Inc.. l.'o. 90-433' 14th Judicial District Court Calcasieu Parish, Louisiana Page - TABLE 4G (Review date 1 January 1990) PLANT START-UP DATE LATENCY PERIOD OF ASL CASES NO OF IN SPECIFIC PLANTS(4-9 CASES) CASES S CHARLESTON USA 1939? 24,30,32,32,34,35,37,38,39 9 AVERAGE PERIOD 33.44 BRIGNOUD FRANCE 1950 11,16,18,26,30,25,34,45 8 25.62 SUNDSVALL SWEDEN 1945 16,19,27,29,31 5 24.40 NIAGARA FALL! 1 USA 1947 15,17,21,23,38 5 22.80 TAVAUX FRANCE 1953 19,16,21,26,25 5 21.40 HILLHOUSE UK 1940 28,25,28,25,26 5 26.40 SPLIT YUGOSLAVIA 1950 20,20,22,23 4 21.25 CMA 010753 CONFIDENT IAI Subject to Protective OHcr i~i Boss v. Conoco, Inc., Ho. 00 - ' 14th Judicial District Court Calcasieu Parish, Louisiana TABLE 4H Page (Review date 1 January 1390) LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT I---------------------------- -- | YEAR OF S CHARLESTON BRIGNOUD |FIRST EXPOSURE USA FRANCE 1 (___________________ | 1939 | 1940 11 2 37 32,38 3 32 45 4 24,34,39 S 6 30,35 7 -- --P--------------- SUNDSVALL NIAGARA TAVAUX HILLHOUSE SPLIT SWEDEN FALLS FRANCE UK YUGOSLAVIA USA 27* 31 15,23 29 28 8 9 1950 1 2 26,30 34 19 38 17 23* 3 4 5 6 7 8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 ___________________ Monomer worker 18 16,25 16 11 20 25 22* 21 19 28 20 1 1 1 26 1 -- 16,21,25 25,26 1 1 1 1 11 1 1t 11 1I ___________ 11 ____________ 1______________1 CMA O1075A CONFIDENTIAL Subject to Protective Order in Ross y. Conoco, Inc. , No. 90-4837 14th Judicial District Court Calcasieu Parish, Louisiana 010755 Page 51 TABLE 5 (Review Date - 1 Jan 1990) 1 1955 17 1 1961 12 14 17 18 19 t 1970 11 2 3 4 5 6 7 8 9 1980 1 2 3 4 5 6 7 8 9 Annual Incidence of ASL Cases (Date of Death) by Geographical Area Western Europe 1 1 1 1 4 1 3 6 6 6 7 5 6 5 7 6 7 10 7 4 North America 1 1 1 1 1 5 2 1 2 1 4 2 4 3 2 2 4 3 3 2 1 3 1 Rest of World 1 3 1 2 1 1 Annual Total 1 1 1 1 2 1 5 3 2 3 5 8 5 11 11 8 10 5 10 5 3 10 8 a 11 3 7 5 Cumulative { Total L1 2 3 4 8 7 12 15 17 20 25 33 38 49 60 68 78 83 93 98 101 111 119 127 138 141 148 153 j Key Events I 1 1 l 1 1 | | | Viola 1 Maitoni Goodrich TOTAL 94* ** 50** 9 153 ________________________ ____________________ -- -- -- _______________ 1 O * Omits It 01 bag extruder 3: ** Does not include the following who are still alive, so far as known: Frl5 and 28, US33 & 36 NOTE: G26 and US24 deleted. | ( t 1 1 1 1 1 1 1 | | I I 1 I | r? 13* J.J* '' <L> O f_ t t1 t ' ! .1 ^ O 1 H* |* P 0w ~6 |O 0 01 rr * ^1 It H* l< O C+ 0 . 0 Oo VO S 1^ CT rj " a TABLE 6 (Review date 1 January 1990) KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD 1955 A 7 8 9 1960 1 2 3 4 c 6 7 8 9 FI G1 Cl C2 US8 C3 US5 Cz2 C4,C5,US4,US7,US10 US12,US16 Viola 1970 Swl US11 1 G2 2 Nl,Sw2,UKl,It2 C6.US2 C7 Maltoni 3 G3* C8.US1.US3.US23 Y1 ,Y2,Czl Goodrich 4 G4.G5.UK3 C9.US13 5 6 7 8 9 1980 1 2 3 4 5 6 7 8 9 F2,?3,G6,G7,G8,It3 Bl,F4,F5,F6,F7,Sw3 F8,F9,G10,Gll,G12,Sv4 F10,F11,G9,G13,G15 G16.G17 F12,F13,UK4,UK5,G18 UK6, UK7,G19,Sw5,G20,G21US It4,F14,UK8,G22,G23 UK09,It5,F17,B2,G24,G25,G30 UK10,F16,F18,G27,G29,G35 UK11,UK12,F19,F20,G28,G33, G34 F21,UK13,It6,It7,G31,G32, G36,G37,G38,G39 F25,F26,UK14,UK15,UK16 F22,F23,F24,F2 7,Spl,UK17 US6,US9,US18,US26 US19.US20.US22, C10.US21. US27.US28 US17, US29, US30.US32 US31.US42.C12 US35, US34, US38 US37.US39 Cll US40.US41.C13 US43 Japl Jap2,Y3 Y4 Jap3 TOTAL 94** 50** 9 CM* 010756 * Aerosol can filler (G3) ** Does not include the following who are still alive, so far as known; F15 and 28, US33 and 36 NOTE: G26 and US24 deleted. _ CONFIDENTIAL Subject to Protective Order in Poes v. Conoco, Inc., No. 90-4337 14th Judicial District Court Calcasieu Parish, Louisiana Page ' - TABLE 7 (Review date 1 January 1990) ASL CASE NUMBERS BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION (EXCLUDING It.01) '" KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD 1939 40 1 2 3 4 5 6 .7 8 9 50 1 2 3 4 5 6 7 8 9 60 1 2 3 4 5 6 7 8 9 Frll,Frl6 Fr28** Frl4,Fr24 UKl,Fr23 Sw2 Frl,Fr3.Sw4 Sw3 Fr9, Frl7 Frl2,Fr4 Fr7,Nl,UK8,UK9 Swl,UK5,Fr20,G30 G3* G15,It3,G31,G33,G36 G7,G8,G19,G38,Fr27,UK4 G11,G16,G18,G23,G28, G32,Frl5** FR10.G1,G34,UK15 Fr8,G4,It2,G2,UK12 Fr6,Bl,Fr22,It7 Fr2,It4,Frl9,Fr21 G5,G13,G25,G28,It6 G9,G10,G12,G17,G20,G22 G6,UK6,G21,B2,G29,Fr25 Frl3,Frl8,Fr26,UK7, UK16.UK17 Sw5.Spl FrS.UKU UK3, UK10.UK14 It5 UK13.G35.G39 G24.G37 C3.US27 US13, US29.US40 C2,US19.C11 C1.C5,US5,US7,US28,US35 C4,US3,US9,C12 C7,C9,US8,USU.US21.US31 C6.US22.US26 US1 US12.US41 US16 Y2, Cz2 US10, US32 US4 CIO, US37 Japl.Yl US18.US33** Y3 US 2, US 17, US20, US 34, US43 US36** C13 US23 Czl Jap2,Y4 US39 C8 US6 US38 US 30 Jap3 US42 Viola 70 1 2 Maltoni 3 Total 96 52 9 * Aerosol can filler (G3) ** Frl5, Fr28, US33 & 36 are still alive, so far as known NOTE: G26 and US24 deleted. CHA 010757 JjPJTFlDBNTTAT. 14th Judi^TDi^^t Court Calcasieu Parish Lt ouisiana (Review late l January 1;90) TABLE i WESTERN EUROPE PVC PRODUCERS - START-'JP DATES vs ASL CASES fOMITTLSG .1-03 S It.OM 1------------- 1--------------------- T----------------------- 1----------------------------- 1-------------------------- T"------------------------- -------- , I START-UP| COUNTRY MANE | COMPANY NAME I LOCATION | ASL CASE NUMBER 1 YEAR OF ! 1. YEAR 1 1 1 1 1st E/dosutb 1 1 1931 I BASF 1Ludwiashafan 1 1 1 1933 (West Germany |Uacicer I Burghausen |04,07,11,15,23,24|57,54,55,53,55,69, 60,nil 1J J 1 125,31,32,33 155.53 ! 1 1933 1 Italy iMootecatini lAcaa 1 1 | 1 1939 |Prance |Rhone-Poulenc/ 1st Fons 103,09,10,11,14 146,48,56,41,43, i 1J Ichloe/Atocham J 115,16,17.23.27.23155.41,43,44.54,42 i 1 1940 1 United KinadaallCI/EVC iRuncorn (Closed 1948) 1 1 lunlted KiogdopIlCI/EVC iHillhouse 101,04.12.16.17 144,54.57,53.63 1 1945 1 Sweden 1Keoanord/Nobel ISundsvalHStockvikllOl.02.03.04.05 151.45.47.46.64 1 1946 1 France___ iRhone-Poulenc |Roussillon loi 146 1 1946 | United Kingdom|BF Chm/ICI/EVC|Barry |03,05,06,07,08,09|66,51,62,63,50,50 i 1 i 11 1. 1 110.11,13,14.15 166.65.63.66.56 1 lUest Germane ICWH/Hule 1 m? iBelaiu Isolvar I Marl [Jeamme S109.10r,29 161.61.62. I58.62 ! 1950 I France |PCUK/Atocham iBrignoud |02,04,05,06,12,19|59,49,65,58,49,59, 1I 1 120.24 151.43 1 |France |Rhone-Poulanc/ |st Auban |07,22 |50,58 - 1 1 .... Ichloe/Atocham 1 11 1 1 Holland Isbell Iperni*. Rotterdam 1 1 l i 1 i i i i 1 1 1Norway 1 Norsk iHeroea. Pormnmn loi 150 1 1 Wl 1 Switzerland 1 1952 1 Italy 1Lonza/ICI/EVC ISina Inontediaan/ |Terni 1 |07 1 158 i 1 11 iMcolefen 1 11 i 1 1 Italy iMontarHam/PVC 1 Porto Mambera 102.06 157.60 1 1 1953 1Halvlc/Solvae lHallain 1 1 I 1 1 France Isolvay 1 1Italy ISolvae iTavaint 1 Ferrara 108.13.18.25,26 I57i63.63.62.63.... 103 153 1 1 1 |Spain |Rio fiodaoo iHenani 1 1 i I |United Kingdom|BIL/BI?/NORSK lAycliffa 1 Itfeat Germany iHnachet iGendnrf 1 118 1 155 i 1 I 1954 lUast Germany iDynMit/Hala iTroiadorf 11 |(since 1.1.89) 1 11 1 1 101,02,08,12,16,11 156,57,54,61,55,61, 119,20,21,22,27,30|54,61,62,61,55,51 134.35.36.37,33.39156.63.53.69.54,63_ 1 1 1 | 1955 11 1 1 1956 1Spain ICalaee J 11 1 I1 101 164 1 | 1958 IWest Germane lSbeinberg 1 1 1 1 1960 a I Kl 1--J * t^o3 h <15 > s 1 o cn o S - f ti a(3 rOt *^H oo + 3 Wo t* | | | | | 1961 1962 1965 H S3! W P o o c Sf | I R M -p ^ o* 1 -) P Pe o * * | | 1966 1967 so O2 +> o -P o . '* | | | 1966 e-pfi *i3j | 1969 Vrg P 0 w I1 S^ o L P4 1 Italy 1 llieat Gemene 1 Portunal lltalf lUeet Germene lut Gereetue 1Greece lltalr lANIC/SC Ravenna| /ESC .. 1 Ravenna iTonie/TCT/CTP lualdehnt iRWndla) ICitee lOnorto IPeneae iMlra. Venice 1Cologne iRalan lEeen Phiuu Istavelar iRsBnica/EVC. _ lr9nllH firrMim 11 1 104 159 1 106.13.28 162.60.60 1 11 1 11 _____ 1 121 159 .1 11 1 105 167 1 J1 1 160 1 1 ......... . 1 1 1 ......... 1 1 1 J___ 1 | CMA 010758 1J , J------------------ 1 1 Continued Table 8 - Continued WESTERN EUROPE PVC PRODUCERS - START UP PAXES vs ASL CASES (CHITTING GQ3 & It.01) 1------(------------------------ 1---------------------------- 1------------------------------ |START-UP| COUNTRY NAME | COMPANY NAME | LOCATION 1 YEAR__ 1________________ __________________l | 1970 1Italv ISIR 1 Porto Torres Sar 1 United Kingdom1ICI/EVC____ ____ 1 Runcorn___________ | 1971 iBeelan Bav | 1972 1 Finland iPwlr-- ISvartback 1Holland | 1976 |France IDSM iBeek Liaburs |soc Art D'v iny1|Mazingarbe JIfCDFl ____ 1____________________ 1 1977 | 1982 |Weat Germany |ICI/EVC |Voslapp 1l - 1 1 .... L, , , --,, -I., - 1 | ASL CASE NUMBER | | _ ... 1 1 1 |1 |1 1 .1 11 I ......... 1 11 I1 I1 11 11 1l 1 - --. .1 YEAR OF 1st Exposure ... -........ .. -- | 1 1 1 --1 * Laboratory worker in Raaaarch Department CMA 010759 co:;_ Subject to Protective Order in Boss v. Conoco, Inc., Ho. 90-4337 14th Judicial District Court Calcasieu Parish, Louisiana T TABLE 9 Page , (Review date 1 January 1990) USA PVC PRODUCERS - START-UP DATES vs ASL CASES 1 -- -------------------------------------1----------------------------- 1------------------------------- |START-UP COMPANY NAME LOCATION | ASL CASE j YEAR OF 1 YEAR j 1939? *UCC S Charleston 1 NUMBER I 1st EXPOSURE j07,13,19,21,27 j44,42,43,46,41 128,29,31,35 144,42,46,44 Dow Midland (made | | Saran copolymer) 1 I I 1940? *BFG Louisville |01,02,03,04,05,148,55,45,52,44, |06,09,16,17,22,|62,45,50,55,47, I 1946 *UCC/Dow 126,33,34,37,40 147.54,55,53,42 Texas City (Partially closed 1977)1 1 1947 I 1948 Goodyear Firestone/ Niagara Falls Pottstown 08.10.11.20.41 146,51,46.55.49 12 j 49 | 1950 Occidental Uniroyal Monsanto Painesville (closed 1975) Springfield 32 1 1 1 |51 | 1952 Dow (Closed 1975 Midland (No PVC since c 1975) 1 1 BFG Avon Lake 18 154 1 1953 Diamond/BFG Deer Park 1 | 1954 General Tire/ ** Ashtabula 36,43 56,55 % DiversiTech (Closed 1983. Reop<*ned 1986 by Vvq<in) | 1956 Air Products Pensacola (Pace) 1 Atlantic Refining Brooklvn(Closed late 1960s) Borden Leominster (Closed 1984) Conoco Hebronville (Closed 1975) BFG Niagara 1 Great American Fitchburg |23 58 Plastics (Closed 1983) 1 Hooker Hicksville (Closed 1980-81) Pantasote Passaic(Closed 1984) 39 60 | 1957 Atlantic Tubinq Cranston (Closed 1967) Tenneco/ Flemington NJ |30 59 Occidental (Closed 1985) 1 | 1958 Kevsor Century Saugus, Cal 1 Air Products Calvert City(Paducah) 38 63 (Closed March 1982 Re-ooened Octolser 1983) | 1960 BFG Long Beach, Cal (No PVC now. Formerly shown as Watson) Borden Illiopolis 1 1962 Tenneco/Occidental Burlington NJ | 1963 Conoco/Vista Aberdeen, Miss Stauffer Long Beach. Cal (C Losed 1982) | 1965 Conoco/Olin Assonet, Mass 42 68 Ethyl (Closed by Olin 197!U__________________ Baton Rouge (Closed 1984) \ 1966 Diamond/Georgia Delaware City Gulf Gen Tire/Pantasote Mt Pleasant W Va (Closed 1982) BFG Henrv. Ill Stauffer/Formosa Delaware City (Sold to Formosa 1981) | 1967 Allied/Robintech/ Painesville, 0. (No PVC made by Robintech. Georgia Pacific Gp converted to polystyrene) I Hooker/Occidental Burlington NJ 1 1 1 1968 Firestone/Occidental Perrwille (Closed 1982) i | Continued CMA 010760 Page ;7 TABLE 9 (Continued) USA PVC PRODUCERS - START-UP DATES us AST. cases START-UP YEAR 1969 1971 1972 1973 1974 1975 1979 1983 1986 COMPANY NAME BFG Goodvear/BFG Conoco/Vista Nat Starch Borden Atlantic Tubing/ Tallvrand Shintech Certain-teed Georgia Pacific/ Georaia Gulf Tenneco/Occidental Firestone/ Occidental Formosa Vvaen ** LOCATION Pedricktown NJ ASL CASE NUMBER Plaauemine Oklahoma Citv Meredosia. Ill Sorinafield Cranston RI (Closet l 1982) Freeoort. Tex Lake Charles Plaquemine, La Pasadena. Tex Addis (formerly sh<swn as Plaauemine) Point Comfort. Tex Ashtabula. Ohio YEAR OF 1st EXPOSURE * My databank has no information on UCC before 1946 or BF6 before 1950 ** Refer to same plant at Ashtabula, bought by Vygen from DiversiTech. NB Some of the plants in this list were closed down, some have changed ownership over the years, some have changed their product. J CMA 010761 ------- urd loss v. Conoco, Inc., No. 9i 14th Judicial District c>. Calcasieu Parish, Louis! TABLE 10 Page ; l (Review date 1 January 1990) CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP YEAR COMPANY NAME LOCATION ASL CASE NUMBER YEAR OF 1st EXPOSURE 1943 (1941?) Goodrich Shawinigan (Formerly Gulf) (Formerly Shawinigan Chemicals) (Formerly Canadian Restins & Chemicals) 01,02,03,04,05 44,43,41,45,44, 06,07,08,09,10, 47,46,61,46,53 11,12 43,45 1951 Monsanto La Salle (Closed 1* 175) 1957 Goodrich Welland (Niagara) 13 57 1966 Esso (Imperial Oil) Sarnia 1979 Diamond Shamrock Alb/ Fort Saskatchewan BP Goodrich CMA 010762 CONFIDENTIAL Subject to Protective Order in Boss, y. Conoco, Inc,. Ho. 90-4837 14th Judicial District Court Calcasieu Parish,. Louisiana Page (Review date 1 January 1990) TABLE 11 EASTERN BLOC FVC FACTORIES - SIARI-UP DAIES-VS ASL CASES T------------------------ 1 1 START-UPI COUNTRY NAME | COMPANY NAME | LOCATION 1 | ASL CASE 1.......... | YEAR Of YEAS 1 1 1 1 NUMBER iPre l939lEaat Germany 1 State Comoanv 1l 1941 1 State Coroi 1Vladimir et al 1 1 1950 (Juno Vinil ISnlit 101.02.03.06 153.50.54.58 1951 iNovakv 101.02 157.50 1955 11 1956 1Rumania llcechlm 1 1 1957 1 Poland 11 |Rumania |State Comp* |Timavani 1 1 11 llurda 1 _L 1958 jRianov 1 L 1959 11 1961 11 1963 lYuooalavia lOhia ISkooie 1 l 1965 1 _ ... L 1967 llamow 1 L 1969 1 __ ! 1970 11 11 1972 1L 1975 1 ... 1 1 1. 1976 IHId 1 _L 1977 A --i -- - 11 l -- 1 1 1 | CHA 010763 - ^~-jn - j.'. u Subject to Protective Order in R gs t. Conoco, Ino., No. 90-4837 14tb Judicial District Court % .Calcasieu Parish, Louisiana Page n TABLE 12 (Review date 1 January 1990) JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP YEAR COMPANY NAME 1950 1951 1952 1951 1955 1956 1957 1960 1964 1966 1967 1968 1970 1971 1973 1974 Chisso Corp Kanegafuchi Kag Tekkosha Mitsui Toatsu Mitsubishi Mon Sumitomo Kas Denki Kagaku Nippon Zeon Toa Gosei Rvo-Nichi Nippon Zeon Nisshin Kasaku Kureha Kasei Shinetsu Kas Denki Kagaku Kaneeafuchi Kaa Chisso Com Tokuvama Seksui San Arrow Kagak Sumitomo Kaa Ryo-Nichi Shinetsu Kas Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yuki Mitsui Toatsu Nissan Kagaku Shinetsu Kas Tekkosha Asahi Glass Toyo Soda 1975 1977 Central Kagaku Tovo Soda Unknown LOCATION Minamata Osaka Sakata Nagoya Yokkaichi Kikumoto Shibukawa Kambara Tokushima Uozu Takoaka Takeo Nishiki Naoetsu Ohmi Takasaao Chiba Tokuvama Tokuyama Chiba Mizushima Tokuvama Mizushima Goi (Chiba) Kashina Kawasaki Sakai Chiba Kashima Yokkaichi Havatsuki Sakata Yokkaishi Kawasaki Yokkaichi Kashima ASL CASE NUMBER 02 01. 03 YEAR OF 1st EXPOSURE 58 53. 65 CMA 010764 c own spatial Subject to Protective Order in Rosa V. Conoco. Inc, , Ifo. 90-4837 14th Judicial District Court Calcasieu Parish, Louisiana (Review date 1 January 1990) TABLE 13 SOUTH AND CENTRAL AMERICAN PVC PRODUCERS START-UP YEAR 1953 1954 1955 1956 1960 1961 1965 1966 1967 1968 1970 1971 1975 1976 1977 1978 1979 COMPANY NAME Monsanto Mexica Policvd Geon Do Brazil Elchlor/Solvav Elactrochlor Violastic Induoa PET Columbiana Carburo De Col Plasticos Omeea SOC Paramonea Primex Policasa Petro Dow Polimeros Max Rico Chemicals Petroolas Indust Resistoc Huls Brasil Polychem Policvd PET Camacari LOCATION Lecheria (Mexico) Mexico City (Mexico) Sao Paulo (Brazil) Sao Caetano (Brazil) Capitan Bermudez(Argentina) Mendoz (Argentina) Cinco Saltos (Argentina) Cartagena (Colombia) Medellin (Colombia) Mexico Paramonea dPeru) Puebla (Mexico) Managua (Nicaragua) Conception (Chile) St Martin Puebla (Mexico) Guvanilla (Puerto Rico) EL Tablazo (Venezuela) Tlazeala (Mexico) Cubato (Brazil) El Salvador Coatzacoalcos (Mexico) Camacari Bahia (Brazil) ASL CASE NUMBER YEAR OF 1st EXPOSURE CMA 010765 Subject to Protective Order I ^ossv. Conoco, Inc., Wn 90.u 14th Judicial District Court Calcasieu Parish, Louisiana t Page (Review date 1 January 1990) TABLE 14 AUSTRALASIAN FVC PRODUCERS START-UP DATES START-UP COMPANY NAME YEAR Mid 1950s ICI Australia 1960s B F Goodrich Late 1970s ICI Australia LOCATION Botany, Sydney Melbourne Laverton Melbourne ASL CASE NUMBER YEAR OF 1st EXPOSURE 01076* t .cowfije^tt at. Subset to Protective 0-^t. -2H. v* Conoco. Ino.. Uo. 9Q 14th Judicial District Court Calcasieu Parish,, Louisiana I Page (Review date 1 January 1990) TABLE 15 MIDDLE EASTERN PVC PRODUCERS START-UP DATES START-UP DATE Sept 1986 COUNTRY NAME Saudi Arabia COMPANY NAME LOCATION National Plastic Company (Ibn Hayan) Arabian Petrochemical Company Mediant Al-Jubail Al-Sinahyah 10767 CONFIDENTIAL Subject to Protective Order In Robb v. Conoco, Inc,, No. 90-4837 14th Judicial District Court Calcasieu Parish, Louisiana Page jL (Review Date 1 January 1990) TART.H 1ft NCTIBBa OF FACTORIES IM THE WOSU PRODPCTHR pur 3o far a* known t 1 January nwn (See Table* 8-15 of this ASL Register) Western Europe USA ftwijuU Eastern Bloc Japan South and Central Aaarlca Aostmlaala Middle East CLOSED 1 20 1 22 OPEW 53 30 4 23 36 22 3 1 172 CMA 010768 _ CONFIDENTIAL SutTJect to Protective Order In Rosa v. Conoco, Inc., No. 90-4837 14th Judicial District Court Calcasieu Parish, Louisiana 1 31 4 S Si HRV -- !! 4 7 9 MKH -- i! ii.i to a 13 13 H 13 SETora or USKUSUU. onn OCOMJIOi lb ii. 1 CMA 0 1 0 7 6 9 fiutljact to Protective Ordir in Ro b b v . Conoco, In c ., No. 90-4837 ;''' 14th Judicial D is trio t Court iV;.. C a lca sie u P arish* Louisiana *T'/ka 'W i M cr g ^* S Sf|sfr |> ^ Lj CT V #2snO ,h * 2CT. ? M*+ t'-: h4 * < ' o tt !2j r* pp. 2*+. o. O f>cH 5. O VO CL