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AR 886 - 0918 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (DAPHNIA MAGNA) TEST SUBSTANCE Identity: A mixture containing perfiuorooctanesulfonate, `which may also be referred to as PFOS, FC-95, or as a componenotf FX-3104. (1Octanesulfonic acid) (CAS # 2795-393). Remarks: The 3M production lot number was not noted. The test sample is FX-3104, 6%. Current information indicates it is a mixture of 0.48% PFOS, 14.09% diethylene glycol butyl ether, 59% water, 17.6% ethylene glycol, 1.44% sodium octyl sulfate, 4% inhibitor, 2.0% polyoxyethylene monooctylphenyl ether, 1.25% propane sultone foamer, 0.03% sodium lauryl sulfate, and 0.1% benzotriazole. ~ The following summary applies to a mixture with incompletely characterized concentrations of impurities. Data may not accurately reflect the toxicityof the fluorochemical componentof the test sample. METHOD: Method: Not given. Type: Static acute GLP: No Year completed: 1985 Species: Daphnia magna Supplier: In-house cultures. Originally obtained from U.S. EPA-ERL, Duluth, MN. Analytical monitoring: Temperature, pH, and dissolved oxygen. Exposure period: 48-hours Test organism age: Statistical methods: <24 hours old ECs values calculated using logistic regression methods (probit analysis). Test conditions: Dilution water: Carbon-filtered well water. Dilution water chemistry: Not given. Lighting: Not given. Stock andtestsolution preparation: prepared by dissolving 1000 mgoftest A primary substance stock solution was in 500 mL water. Exposure concentrations were prepared by additionofstock solution to each vessel. Exposure vessels: 250 mL glass beakers containing 200 mL exposure sNoulumtbieonroatfaredpelpitchatoefs6: cm 2 . Numberof daphnids per replicate: 10 Number of concentrations: five plus a blank control Water chemistry during the study: 002993 pH range (0-48 8.18.2 hours): (control exposure) Temper7a.t7u-r8e.1ra(n1g0e00(0m-g4/8Lhoeuxrpso)s:ure2)2 C Dissol8ve.d99ox.y3gmegn/rLa(ncgoentr(o0l-4e8xphoosuurrse)): 7.5-9.3 mg/L (1000 mg/L exposure) RESULTS -- Nominal concentrations: Blank control, 100, 180, 320, 560, and 1000 mg. Element values: 48-hour ECzo = >1000 mg/L. Element values based on nominal concentrations. Remarks: Substance RTeesmtairnkgswafiseldc.oTnhduecvtaelduoens a mixture reported aapspldyetsoctrhiabetdmiinxttuhreeTaensdt not the fluorochemical proportion alone. CONCLUSIONS The test substance 48-hour ECso was determined to be >1000 mg/L. SPuaublm,itMtienrn:esot3aM, Company, 55133 Environmental Laboratory, P.O. Box 33331, St. DATA QUALITY mReeltihaboidliftoyl:loKwieidm.isTchherasntkuidnygl=ac3k.s iSntfuodrymaltaicoknsodnespcurriipttyioofntahnedtersetcosrudbsstofance and analytical confirmation of the amount of fluorochemical proportion in solution. REFERENCES ~~ TSth.isPasutlu,dyMNw,asLacbonRdeuqcuteesdtbnyutmhbee3rMC1C1o1m1p-a2n,y1,98E5n.vironmental Laboratory, oTHER Last changed: 6/26/00. 002994 EE Se wcslizz, TEST Tes Mumm iz CHEMICAL TESTED AX 3/04 5% LOT. TEST ORGANISH.RAA00AUER SOURCELSE fh DATE [IW2 72 Y AGE OF TEST ORGANISMS:<24 hrs. old instars Caries 6. oraanisns per TREATHLOENL TEST VESSEL: 250m] Pyrex glass beaker TEST SOLUTION VOLUME: 200ml BERTH? 6cm TINE STATE S/ASgpl DATEstarren_L,A/S bare cmeree2 [B/E DILUTION WATER Carbon-filtered well water(Temp. 22C, 0.0._Z.3 ppm, HE. / ) EE FETE VETSESSETY [cinointci.al|| aTmootualnt|[Tota2l4vHoo.urs 48 Hours | otal to. [T*l =T a 5 Te TTe 0 kd ad] elolw on TT14kiky hzlisloolTiTn170 kis WxlepfoolTmTe14 bded Wllenlselo TT1 obab =ShecololTTT 5bz] C1 1TTT T1711 L 1 TT TT T1711 PE tele COMMEN:T*S 221321 Sets. sohbet. M000gl tom doa Linh = & Lohr ~Zs ater nsoLiglThe ncqpareshlae Sudh fitle Lo)adios 27 Fe doiats SECONDARY EFFECIS pea]CT 1 1 1 1] 1 1 1 | rt 1 1 (tr 1 "1 1] CL11 or 002995 : AQUENAVTIIRCONTMOEXNITCAILTY LADBAOTRAATSOHREYET WCHL TESTTYPE ZnAue Sz CHEMICAL TESTED Ay AY 4% or. TEST ORGANISM igtt Uli ORCELSD= one [I WE JA ) AGE OF TEST ORGANISHS: <28 rs. 01d instars (veanetds) 10. ORGANISHS PER TREATWENT 2 TEST VESSEL: 250m Pyrex glass beaker TEST SOLUTION VOLUME: 200m] DEPTH: Gem TIME STARTED SZAS uel DATE sTRiEnZLASowe meenS/A/ES OLLUTION WATER lee water (Temp. 22.C, 0.0. ZX ppm, pH 2./ ) WANSUS gr 07 Dobie Foy (95% Confidence units) A000mall TEST [rmeiat 24 fours VESSEW cone. | mount [Total to. Jo 8 fos frotal wo. T 5 e EETPo1a E1 LRol Eoka) lolol oo[T 5 RT is blooe TT15s bila kesl=zolmelo TT10ledad elloae 2 | 1 bo mp gos Toh n o20 o FTcTo 17744] CTT1-71r TT] CT TT -T171T 1 IT] [restore ec |=277 1_227 | Coa Comets: %Lapring e-e stk lotion Es 2 [7/RS F=Z 2K 0000p RS] Kod fun = Zs o LutneaterZany Ln Sclidle ln water a2 . ZtGeutd- samp. Lsperintace: SECONDARY FE EFFECIS Leomp pen| el ci rr rr 1| ] --1 -- rr 1 1 002996 Commas TABLE I. SUMMARY OF ACUTE TOXICITY OF LY=/07/ '% Lisa,hrs) ------ TTT P--rr-- To DAPENIA MAGKA UNDER _SYal7/C. xvosure conprrrons!) eaim t CONTROL --loo Cc c Asc c c 220 & c Sk doco o ] FE EE | EC, (95% CONFIDENCE oars)? 30 Cagnn 2000 > 1000 5g