Document x1NEQnyLYkd4yD2a8p9a7n2eE

CO NFIDENTIAL CONTACT REPO RT Date: M arch 10, I960 , P la c e : C alifo r n ia R e se a r c h C o r p o r at io n , San F r a n c isc o , C a lifo r n ia P eople p resen t - Stan d ard O il Com pan y (Californ ia): M e ssr s. C u r t iss, G ar d n e r , H a u se r , M ac G r e go r , Sp en ce and R ich ard son E. I. duPont: M e ssr s. Kean e, M cllh en y, Sab in a an d T aft Ketterin g Lab oratory - D r. Keh oe Eth yl Corporation : M e ssr s. G ib son , H e sse lb e r g, an d Koeh n le Th is m eetin g h ad been called by M r. M acG regor fo r con sid eration of the d etails rem ain in g b efo r e th e co m m e r cializat io n of X-105A . Th e follow in g it e m s a r e in the o r d e r of th eir d isc u ssio n . D r . Keh oe w as ask ed fir st to com m en t on the statu s of pum p m ark in g sign s an d the am oun t of X-105 th at w ill be p er m itted in g a so lin e s. He sa id h is u n d er stan d in g w ith th e p eop le of th e Su r geon G e n e r a l's o ffice w as th e m axim u m con cen tration of X-105 w ould be th at givin g a w eigh t of le ad equ ivalen t to th at con tain ed in 4 m illilit e r s of T E L . On the m atte r of pum p m ar k in gs he sa id th at ch an ges in th e pum p m ar k in gs sh ou ld n ot be co n sid e r e d of im m ed iate im p ortan ce, but cou ld be done grad u ally on a m ain ten an ce b a sis. He said th at sin ce th e Su rgeon G e n e r al's office h ad o r igin ally sp e cifie d the w ordin g on the pum p sign s as w ell a s th eir siz e , he h ad, as a m atter of co u rtesy , in qu ired by le tte r to D r. P r ic e h is view s on the sign s. He h ad n ot a s y et r e ce iv e d an an sw e r fr o m D r . P r ic e , but a ssu m e d th at su ch w ou ld b e r e c e iv e d w ith in a few d ay s. D r . Keh oe su gge st e d th at the sign s sim p ly r e a d "C o n tain s Le a d An tikn ock Com pou n d s." T h is w as agr e e d a s bein g su itab le by du P on t, Eth y l, an d Californ ia r ep resen tativ es. Th e C alifo r n ia people n ext r a ise d the qu estion about the ap p licab ility of C a lifo r n ia 's "A n t i- su b st it u t io n " A ct . T h is A ct is a im e d a t p r e v e n t in g a d u lt e r a tion of c u r r e n t ly - m a r k e t e d p r o d u c t s. W h ile it w as a g r e e d b y t h o se p r e se n t th at it seem ed u n likely th at the su bstitu tion of X-105 fo r a ll o r p ar t of th e T E L cu r r en tly in gaso lin e s w ould fa ll tin der th is A ct, th e C alifo r n ia people fe lt th at in o r d e r to k eep th e ir own sk ir t s clean th ey m u st ad v ise the Se a le r of W eigh ts an d M e asu r e s of th e st at e . It w as agr e e d th at th is w ould be done on ly aft e r D r . K e h o e 's d isc u ssio n w ith D r . M e r r i l l , H e ad o f C a lifo r n ia 's D e p a r t m e n t o f P u blic H ealth . Contact Report P age 2. C a lifo r n ia r e p r e se n t a t iv e s sa id th at th ey w ou ld b e m ar k e t in g in W ash in gton O regon C aliforn ia, A lask a, H aw aii, A rizon a, Idah o, Utah , N evad a, an d T e x a s. Th ey in qu ired a s to D r. Keh oe's in terp retation of the P u b lic H ealth le t t e r su ggest in g th at th e st a t e s in w h ich m ar k etin g w ould be u n d ertak en be ad v ise d . He sa id h e th ough t it w ould be in ad v isab le to go to th e st a t e s on an in dividu al b a sis sin ce th e P u b lic H ealth people in volved m igh t not u n d erstan d w h at w as goin g on . He sa id , h ow ever , he w ould co n su lt on th is m a t t e r w ith D r. M e r r ill who is v e r y active in th e A sso ciat io n of State s P u b lic H ealth p eop le. D r . Keh oe said h e w ould p r e fe r to ad v ise th e se p eople in fo r m ally du rin g th e co u r se of a r e gu la r m eetin g w h ich w as com in g up. At th is poin t th ere w as som e d iscu ssio n of th e e ffect of su b stitu tion of X-105 fo r T E L on th e am ou n t of o r gan ic le a d th at w ou ld b e fou n d in th e blow by g a se s fr o m en gin es. M r. H e sse lb e r g in d icated th at Eth y l h ad sk etch y d ata in th is a r e a an d th at X-105 r e su lt e d in m or e o r gan ic le ad in blow by g a se s th an did T E L. He em p h asized , h ow ever, th at th e to tal con tribu tion fr o m th is so u r ce w ould be v e r y sm a ll. No d ata w ere qu oted, sin ce we fe lt th at we n eeded m or e r e su lt s to be on fir m grou n d an d, lik e w ise , w ere n ot an xiou s to r ev eal our data to com petition . The rem ain d er of the m eetin g w as devoted to the d iscu ssio n of the data n e c e ssa r y to sa t isfy th e r eq u ir em en ts se t forth in th e le t t e r r e ce iv e d by D r . Keh oe fr o m the Su rgeon G e n e r al's o ffice. It w ill be r e calle d th at the le t t e r in d icated th e Su rgeon G e n e r a l's office w ould exp ect fr o m th e T E L in d u str y at the en d of a y e ar a r e p o r t on th e e ffects of su b stitu tion of X-105 fo r T E L. D r. Keh oe in d icated th at so far as the m an u factu rers w ere con cer n ed , th ey w ould n eed to follow plan t h az ar d s in p r e tty m u ch th e sam e fash io n th at th ey do at p r e se n t , an d at the en d o f a y e a r b e p r e p ar e d w ith enough d ata to com p are X-105 an d T E L . He an ticip ates no p rob lem in ob tain in g the d ata, n or does he an ticipate an y p ar ticu lar ly sign ifican t d ifferen ce betw een X-105 an d T E L. D r . Keh oe sa id th at d ata w ould be n eed ed b ase d on th e situ atio n w ith in r e fin e r ie s an d w h ere exp osu re is on ly by people u n der clo se su p e r v isio n , an d exp osu re to the pu blic w h ere th ere is a lack of su p er v isio n . Coverin g fir st th e r efin er y o p er atio n s, he sa id th at he fe lt th at tan k clean in gs m igh t o ffe r a p oten tial h az ar d , but if p r e se n t safe t y p r e cau t io n s u se d w ith T E L a r e follow ed e xactly , th er e sh ou ld be no p r o b le m . He sa id th at a ll a r e a s in th e r e fin e r y in w h ich X-105 is to be h an d led w ould n eed to be m on ito r ed fo r exp o su r e d ata, an d th at the people in volved in the h an dlin g w ould h ave to be ch eck ed fo r r e je ctio n of le a d in u rin e an d fo r le ad con ten t of blood on a m o r e frequ en t b a sis th an is n o r m al p r a c t ic e . He sa id th at h e w ould lik e to h ave people in the blen din g p lan ts an d at load in g r a c k s exam in ed p e r io d ically , an d h ave blood an d u rin e sam p les on a q u arterly b a sis fo r a p eriod of one y e a r . He sa id th at th is sh ou ld be done at two o r t h r ee r e fin e r y lo cat io n s w h ich w ould co v er th e com p lete r an ge of p o ssib le e xp o su r e . T h e r e w as so m e d isc u ssio n am on g the C alifo r n ia people a s to th e b e st lo cat io n s fo r th is stu dy 0002744 Contact Report P age 3. bu t it ap p ear ed quite d efin itely th at Rich m on d an d B a k e r sfie ld w ould be in volved , an d th at th ere m igh t be a p o ssib ilit y th at Stan d ard of T e xas at E l P a so w ould be u se d fo r th e stu d y. F r o m th e stan dpoin t of th e p u b lic, D r . Keh oe in d icated th at h e w ould n eed d ata b ase d on the st a r t of co m m e r cial u se , an d again at the end o f the y e a r . He said h e w ould lik e d ata fr o m se r v ic e statio n s an d g a r a g e s an d fr o m an y oth er location w h ere gaso lin e w ould be h an dled un der u n favorab le con d ition s. He cited the d e sir ab ilit y of a b ad exp o su r e situ ation su ch a s in a sloppy d ru m -fillin g op eration . He ad m itted th at th is w ould p r o b ab ly b e h ar d to fin d w ith in th e C a lifo r n ia C om p an y 's o p e r at io n s. He sa id h e w ou ld lik e to h ave a total of 200 o r 300 people in volved in th is su r v e y , an d th at he w ould lik e to h ave blood an d u rin e sam p les taken at the st ar t of the m ark etin g operation an d p rob ab ly again n in e to tw elve m on th s la t e r . H e sa id h e w ould n eed , in addition , le ad - in - air d ata obtain ed on a regu larly -p lan n ed b a sis at th e se v e r a l lo cat io n s. At th is poin t th ere w as co n sid e r ab le d isc u ssio n betw een D r . Keh oe and th e C a lifo r n ia an d d u P on t r e p r e se n t a t iv e s a s to w h eth er o r n ot th is w as n e c e ssa r y . D r . Keh oe m ad e th e poin t v e r y em p h atically th at n ot ever y on e a gr e e d w ith h im th at m an w as a d e sir a b le in t e gr at in g d e v ice . He sa id th at som e people in th e P u b lic H ealth Se r v ic e w ould d efin itely w an t to se e exp osu re data an d th ey h ad sp e cifically ask ed fo r it in th eir le t te r . It w as a gr e e d th at th is p h ase of th e activ ity sh ou ld be th e d ir e c t r e sp o n sib ilit y of th e T E L in d u stry , an d the w r ite r agr e e d th at Eth yl w ould p ick up it s sh ar e of th e co st of th is p r o gr am . M r. T aft of duPon t agr e e d th at duPon t w ould do th e ir sh ar e . A fter a gr e at d eal of d iscu ssio n it w as agr e e d th at D r. Keh oe w ould p r e p ar e a m em oran d u m outlin in g h is r eq u ir em en ts in th is a r e a , an d th en th at h e w ould lik e to in sp e ct p e r so n ally the lo catio n s p r o p o se d by C alifo r n ia fo r th is p h ase of the w ork. At th is sam e tim e he w ould sit down w ith r e p r e se n t a t iv e s of duPon t an d Eth yl to a g r e e on th e siz e of th e p r o gr am an d the splittin g of co sts an d w ork. It is exp ected th at th is m ay h appen w ith in th e n ext m on th or six w eek s. Th e qu estion of m ark etin g X-105 in B r it ish Colu m b ia w as r a ise d , an d D r . Keh oe w as ask e d about the ste p s n e c e ssa r y fo r ap p roval in B r it ish Colu m bia. It w as poin ted out by th e w r it e r th at B r it ish Colu m b ia w as on e of the] Can ad ian p r o v in ces in w h ich we h ad ru n in to som e d ifficu lty in obtain in g ap p ro v al of the u se of the 4th m illilite r . D r. Keh oe agr e e d th at th is w as th e c a se . M e ssr s. Koeh n le an d Keh oe agr e e d to se e th at th e st e p s n e c e s sa r y fo r cle ar an ce in B r it ish Colu m b ia w ere tak en c a r e of a s p r om p tly a s p o ssib le. A ltogeth er, th is w as a m o st sat isfact o r y m eetin g in th at it ap p ear s th at m o st o f the qu estion s th at w ere in th e m in d of th e C alifo r n ia p eop le w ere tak en c a r e ' K 0008745 Contact Report P age 4, of. It is eviden t th at C alifo r n ia exp ects th e T E L in d u stry to p ick up the lio n 's sh ar e of th is m e d ical an d exp o su r e p r o gr am , sin ce th ey r e a liz e th at th e r e su lt s obtain ed w ill be u sed by the T E L in d u stry in su pportin g sa le of X-105 to oth er cu stom ers. H JG /d l Copies to: D. M . Guy H. E . H esselb erg R. H erzog R . A. Keh oe G. F . Kirby J. Koeh n le M . M urdock W. R. Perdue L . H uxtable R. K. Scales K . Sw ar t w ood G il W ay H arold J7 G ib son /<J~ 0 0 0 2 7 4 6