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0* CONFIDENTIAL Subject to Protection (Trdnr m
--v~ -gHQC0. Ino. . No. 90-4337 14th Judicial Pistrict Court
tVv.. Calcasieu Parish,, Louisiana
Manufacturing Chemists Association
Minutes of Meeting
TECHNICAL PANEL ON VINYL CHLORIDE RESEARCH
Crystal City Marriott Hotel
Arlington, Va.
April 28, 1976
Chairman Torkelson convened the meeting at 9:00 a.m. The record of attendance is:
MEMBERS PRESENT:
T. R. Torkelson, Chairman T. R. Aalto R. J. Abramov? it z Z. G. Bell, Jr. 0, P. Cohen
(for w. A. Fuhrman) D. E. Cooper
(for R. K. Hinderer) R. L > Gibson W, D. Harris G. K,, Hatfield
(for R,, W,, McBurney) M. N . Johnson F. Kennedy W. C, Koch R. A. Kuna
(for R, E. Eckardt) H. L. Kusnetz R. W,, Laundrie M. W. Palshav?
(for A. R. Lindquist) R. A. Park
(for R. S. Brookman) H. A. Russell H. L. Schmidt, Jr. W. M. Smith J. W. Walker R. N. Wheeler H. M. Zimmerman M. Freifeld
The Dow Chemical Company Tenneco Chemicals, Inc. Hooker Chemicals & Plastics Corp. PPG Industries, Inc. Great American Chemical Corporation
Ethyl Corporation
Gulf Oil Corporation UNIROYAL Inc. Diamond Shamrock Corporation
B. F. Goodrich Company Continental Oil Company Allied Chemical Corporation Exxon Corporation
Shell Oil Company The General Tire & Rubber Company Stauffer Chemical Company
Firestone Plastics Co.
The Pantasote Company Borden Chemical Air Products & Chemicals, Inc. Certain-Teed Products corp. Union Carbide Corporation Georgia-Pacific Corporation MCA Staff
CMA 013987
VDRTP
2
MEMBERS ABSENT:
B. W. Duck J. E. Ertel M. R. Gasque C. A. Johnson S, K. Law A, B, Magram G. Roush
GUESTS PRESENT:
W. R. Gaffey T. J. Gilroy R. V. Johnston M, L- Keplinger E. A. Ledet J. J. Mantell B. A. Schwetz K. L. Spalding F. M. Toca P. G. Watanabe
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British Petroleum Co. Ltd. Robintech Incorporated Olin Corporation The Goodyear Tire & Rubber company Keysor-Century Corporation W. R. Grace & Co. Monsanto Company
Equitable Environmental Health, Inc. MCA Staff The Dow Chemical Company Industrial BIO-TEST Laboratories, Inc. Borden Chemical Air Products & Chemicals, Inc. The Dow Chemical Company Shell Oil Company Tenneco Chemicals, Inc. The Dow Chemical Company
****** *
1, Oral Reports by Contractors
Presentations were made as follows:
TOPIC Teratology
SPEAKER
Dr. B. A. Schwetz The Dow Chemical Company
Metabolism
Dr. P. G. Watanabe The Dow Chemical Company
Animal Studies
Dr. M. L. Keplinger Industrial BIO-TEST Laboratories, Inc.
Mutagenetic Work
Dr. R. V. Johnston The Dow Chemical Company
Epidemiology
Dr. W. R. Gaffey Equitable Environmental Health, Inc.
Dr. Johnston's work was reported here although not
CM* l398Q
VCRTP 3
not a part of the MCA project since it is related to the 1BT studies.
Dr. Keplinger1s talk was substantially the same as the one to be given at the American Industrial Hygienists Association meeting the week of May 17 in Atlanta. The sugges tion was made that the discussion on investigating the effect of contaminated food should be clarified.
All of the work described is done or nearing completion. Summaries of the presentations will be distributed to the Panel.
2. Proposals for Future Research
2.1 Birth Defects
The recommendation of the Research Coordinators reported by Dr. Torkelson, was to defer action until the re sults of the study currently underway by The Center for Disease Control are known. The Panel accepted this recommendation.
2.2 Additional Metabolic Work
Overwhelming approval by the Panel in a letter ballot to recommend the Dow protocol of February 5 to management contacts was reported by the Project Manager. Among the thirty companies supporting the VC project, only two indicated hesitation or objection to proceeding with this work. Following a very brief discussion, the action recommended in the ballot was sustained and management contacts will be asked to support the additional metabolic investigations expected to take about one year and to cost $115,000 (plus contingency funds and administrative expenses as necessary).
2.3 University of Louisville
Dr. Torkelson outlined the Research coordinator's recommendation for favorable Panel action on the proposal out lined in Dr. Tamburro's letter of April 20. It involves the study of immunological systems and electron microscopic eval uation of liver tissue. A primary objective of the work is to develop new diagnostic tools to predict disease resulting from VC exposure. The National Cancer Institute is supporting Dr. Tamburro's work on the application of known methods for the diagnosis and treatment of VC-related health problems in workers. A sense of urgency was relayed by Dr. Torkelson if Dr. Tamburro's staff is to be held together.
Subject to Protective r}-.-ro]?rr iin oss v. Conoco, Inca^io-
14th Judicial ( Calcasieu Pa..
CMA 0 1 3 9 S 9
VCRTP 4
The level of funding requested for this project is about $235,000 per year with possible alternate funding of $200,000 per year (by reducing indirect cost). Since the full Panel has not yet seen the Tamburro proposal (only the Research Coordinators have) and the matter is urgent, the decision was made to vote on supporting this research for one year. This was with the understanding that once the full Panel had a chance to review the proposal it would probably want to support this work for an additional two years.
On motion duly made and seconded the Panel then voted (sixteen to one) to recommend to management contacts that the University of Louisville proposal be supported at the rate of $200,000 for the first year with contingency funds and adminis trative expenses as needed recognizing that similar requests will probably be made in the next two years so that continuity of the effort can be maintained.
3. Minutes of Last Meeting
Minutes of the December 11, 1975 Panel meeting were approved as distributed.
4. Financial Statement
A financial statement dated April 1 is appended.
5. Public Relations
The sentiment of the Panel was that there was no need for a news release or other notification of this meeting outside of MCA. Nearly all of the material covered had been sent to appropriate government agencies in the form of reports. Further more, for those studies that were not yet finished, completion of the work and issuance of the reports were expected very shortly. These will be made available to government personnel in the usual way and in addition it is expected that results will be published in a suitable technical journal.
6, Selection of Vice Chairman
Acting on the recommendation of the Research Coordinators, the Panel voted unanimously for Dr. W. Mayo Smith as Vice Chairman.
Next Meeting
This was left to the discretion of the Chairman.
.COflFlDENT-TAT,
Subject to Protective Order in
5251 v.
Ho. 90-4837
14th Judicial District Court Calcasieu Parish, Louisiana
CMA 013990
The meeting was adjourned at 2:20 p.m.
VCRTP - 5
Minutes Subject to Approval
MF: ec May 22, 1976
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