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^OHIO DEPARTMENT OP HEALTH
Bureau of Occupational Diseases Columbus, Ohio
April 3, 1933
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Supplementary Evidence in the Diagnosis of Lead Poisoning (items are arranged for checking or comment on the given oase)
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P a t ie n t *s N a m e A d d r e s s P h y sic ia n ' s Name D r . Edward F.Ko t e r s h a l l ^ .d d r ess
3771 W. 150t h S t * Clevelan d 0 *
2841 Yf. 25t h S t . ,
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O b je ct iv e i . e . , th e p h y sic ian 's fin din gs^
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1 . P allor (e sp e cially eircum oral)
2 , Blu e l i n e * in gu m (s)
3* Stip p lin g* (basoph ilia of red c e lls)
4 . R e t i c u l o c y t o si s* y^iMe^ZtZZ S,S&O, O o 0
5 . Red cell count(s) ^ .A o o,
P oly ch r o m at op h ilia s^^Zzfz/L
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White cell count(s) / Dj0>c> Mononucleosis
6. Hemoglobin percentage
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How determined
7. Evidence of recent blood changes of retrograde character
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8. Blood pressure finding6s rf
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9. Condition of teeth, gums, mouth
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10. Condition of hand gripping power
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11. Condition of wrist extensors (any actual wrist drop)
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12. Tremor JU ^ Z a s
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13. Patellar reflexes
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Incoordination y jLj^ Z Z Z C ^
Ataxia
14. Ocular palsies ^ A j^ e Z Z Z tZ '^ ^ ^ p ^ .
15. Malnutrition or emaciation
16. Acne or dermatitis
17. Evidence of nephritis
18. Gouty s igns 19. Mental disturbance
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20. Other objective signs^ noted;
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Blue line in gum(s)", "stippling" and "roticulocytDsis" occur in Load Absorption, but, with or without those, it requires significant abnormalities in various ones of the other Objootivo and Subjoctivo findings listed to sustain a diagnosis of
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Subjective, i.e., the patient's complaints
1. Morning anorexia
Metallic (or sweet) taste
2. Hausea or vomiting 'B
3. Acute attacks of abdominal colic
Dyspepsia
4. Obstinate constipation
Diarrhea at onset
5. Headache
Insomnia
6. Weakness (hand grips; use of wrists, legs, feet, etc.)
7. General weakness C L c ^ p t _
8. Rheumatic pains ^ L.-ue^ e^ z :
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9. Disturbed vision
Syncopal attacks
10. Weight: Normal-
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At present. />
11. Other symptoms
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12. Any further coinaent:
Physician's g i g n a t u r e ^ g f ^ j f a Eate J 4 ^ 6 . ^ . / ? . 3 3.;.
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The diagnosis of Lead Poisoning involves evidence of (1) exposure to lead or
its compounds; (2) objective signs of blood changes, of nervous' involvements and
usually nutritional"disturbances; and (3) the presence of a number of the subjective
phenomena above listed. .
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Stippling (also reticulocytosis and polychromatophilia) indicate that lead
absorption is going on at the time.-;. The number of stippled cells found increases as
absorption progresses and is a rough measure of the amount of exposure. Hence
workers showing;stippling without other evidences should have blood examinations
made frequently.'1' StipplingHirith other evidences (see above list of objective and
subjective findings) constitutes acute load poisoning, but acute lead poisoning oc
casionally oxists without stippling (horo roticulocytosis is invariably prominont
and the red colls should always be examined for this condition). When the con-
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dition bocomos chronic, stippling usually diminishes, but is rarely absent as long
as exposure continues or other clinical signs prevail, whale anemia is invariably
present, usually also with polychromatophilia.
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Inasmuch as the accuracy of analytical findings of lead in tho urine and feces
is a matter of groat doubt, tho value of tosts for same in establishing (diagnosis 1
is questionable.
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