Document wqOM3n8VDjLLpVeydM91MVKrD

Industrial Hygiene Digest INDUSTRIAL HEALTH NEWS LITERATURE ABSTRACTS MEDICAL ENGINEERING CHEMICAL TOXICOLOGICAL LEGAL-- decision* and trend* AUGUST, 1948 (VoL 12, No. 8) INDUSTRIAL HYGIENE FOUNDATION 4400 FIFTH AVENUE PITTSBURGH 13, PA. PLAINTIFF'S EXHIBIT W-OCPH^H PLAINTIFFS EXHIBIT FOUNDATION FACTS Foundation Facta la a monthly nowa-lottar iaaued to induatrial concerna holding memberahip in Industrial Hygiene Foundation. The Foundation is a non-profit association of industries for the advancement of healthful working conditions. August, 19^8 NO. 8 Annual Meeting and Conferences. Nov. 17. 18, 19 Plans are progressing for the 13th annual meeting of Members of Industrial j-giene Foundation which will he held at Mellon Institute, Pittsburgh, on November 18. in pest years the program for this meeting is mainly for management representatives from Member firms--officers, department heads, operating men and staff specialists. Meanwhile, arrangements and agenda are being worked out for the four pro fessional conferences. These will be held as follows: November 17: M Physicians Engineers University Club Mellon Institute ff II Attorneys and Compensation Men Hotel Webster Hall NOVEMBER l8: ANNUAL MEETING OF MEMBERS MELLON INSTITUTE November 19: Chemists and Toxicologists Mellon Institute Meanwhile, plans are under consideration for a Ceramic Conference to be held in connection with the annual meeting this year in response to requests from Meaber companies in that industry. This is intended principally for companies in the glass, pottery, refractory, abrasive and related fields. It will probably be held ob November 19. A number of industry representatives will meet here on September 23 to complete the arrangements. Further announcements will be made as plans far the Emual meeting and the conferences develop. lotel Reservations Meanwhile, members should arrange hotel reservations immediately. Hotel debater Hall and the Hotel Schenley promise to do everything possible in providing econmodations. In communicating with them, mention the meeting. Downtown hotels hive also been advised of the dates and their cooperation enlisted by the Pittsburgh Convention Bureau. Mellon Institute Issues 35th Annual Report "Meeting the Needs of Mankind by Scientific Research," the 35th apuual wpart of the Director of Mellon Institute, Dr. E.R. We idle in, has just been issued. Ibis impressive 44-page publication summarizes the diversified research projects, *n*e and applied, currently in progress at the institution--projects ranging from *ork in chemical physics, treatment of waste pickle liquor and silicones, to foods d nutrition, chemicals from corn and new fire fighting agents. The report includes nummary of the work of Industrial Hygiene Foundation as well as a resume of actijKies of the Chemical Hygiene Fellowship of which Carbide and Carbon Chemicals Carp. " the donor..." (Copies of the report will be sent to Foundation Members upon request.) Annual Meeting and Conferences: Nov. 17, 18, 19 AL HYOIENK FOUNDATION 4400 FIFTH AVENUE PITTSBURGH (<). PA Industrial Hygiene Digest - 9 August, lftW? compensation payments, exclusive of medical benefits and excess insurance costs was $8,000,000. Interrupted civilian construction during the war caused a decline to about half that amount. Workmen's compensation claims under the government construction program of the war years were largely under Federal rather than State jurisdiction. Total economic lasses of in dustrial accidents, including medical benefits, excess insurance costs, wage losses, costs of interrupted production, damage to equipment, and other losses are estimated by insurance statisticians to be nearly 10 times the cost of workmen's compensation benefit payments. This cost is borne ulti mately by consumers. It offers a serious challenge to the construction in dustry, labor, and government for a cooperative program to prevent construc tion accidents and a challenge also to the medical profession for the kind of treatment that vill enable disabled workers to return to their jobs as promptly as possible. -- From Authors' summary Industrial Medical Practice 85I Significance of Occupational History in Diagnosis of Silicosis. T.F. Hatch. Radiology. 50. 7^6-750 (June, 194$) (Reprints available from the Foundation) The dusty trades may be divided into three categories in respect to silicosis: (1) known to produce silicosis as a characteristic disease of the occupation; (2) known to be free from the silicosis hazard; ami (5) intermediate industries in which silicosis occurs sporadically. The first two categories present no problem provided the hazard is properly assessed. In the third group, however, the detailed information of the occupational history is of greatest importance, and the adequacy of our present etiologi cal criteria of greatest concern. There is danger in applying the general ized rules too far in the evaluation of dust exposures for the purpose of diagnosis of individual chest roentgenograms. Further laboratory research is needed to improve our understanding of the etiology of silicosis. It is of even greater importance, however, that the independent reading of chest roentgenograms be extended without dependence upon occupational histories. More systematic studies of the type described above are needed in a greater variety of dusty trades, involving exposure to more complex dusts and in cluding, in particular, occupations in which silicosis is an occasional rather than a characteristic disease; others, in which nan-disabling lung changes occur, such as in welders, also require systematic study. The sta tistical. aspect of the problem must be kept in mind. A chest film which is non-specific when viewed alone tabes on new meaning when it Is found to be characteristic of a group of workers similarly exposed. Further confusion with respect to the silicosis hazard in industry can be avoided only by the most critical study of the findings in the borderline dusty trades. The responsibility is a Joint one, shared by radiologists, clinicians, patholo gists, and industrial hygienists, -- From Author's summary industrial Hygiene Digest - 27 August, 19^8 Laboratory Toxicological Studies 888 Asbestosis and Pulmonary Tuberculosis. B. Desmeules, L. Bousseau, M. Giroux and A. Soiris. Sem. Hop. Paris, 2, 1820 ff. (19^7) (French) The authors report from Quebec on asbestos is in the Canadian mines and on animal experiments. They disagree with Gardner's statements that pneu moconiosis due to asbestos is not an important factor in the production and progress of pulmonary tuberculosis, and that the presence of asbestos bodies in the sputum has no value in the diagnosis of asbestos is. Several cases of asbestosis are described; in one, death was due to tuberculosis and asbesto- sis, giving support although not proof for the authors' theory. Two cases of asbestosis with lung cancer are also described briefly. In animal experi ments by Giroux, lung lesions and asbestos bodies were produced in guinea pigs but not in rabbits or dogs. In these animals the author traces the formation of asbestos bodies: fibers reaching the alveoli are rapidly covered by phagocytic cells, movement of the fibers results in microscopic bleeding from damaged alveolar walls; the hemoglobin from the liberated red cells is taken up by the phagocytes which already enclose the asbestos fibers. Sub cutaneous or intratesticular injections into guinea pigs of suspensions of asbestos in olive oil resulted in the production of granulomatous lesions but no asbestos bodies. When, however, the suspension was injected into an area into which 1 ml. of blood had been injected immediately before, as bestos bodies were found after a month. He considers that the presence of asbestos bodies in sputum has significance, since it implies tissue damage in the lungs. -- From Brit. J. Ind. Med. 889 The Efficacy of BAL (2,5-Dimercantopropanol) in the Treatment of Experimental Lead Poisoning in Babbits. F.G. Germuth, Jr. and H. Eagle. J. Fharm. and Exper. Therap., 2, 397-1*10 (Apr., I9I+8) Under given sets of conditions treatment with BAL was not effective in preventing death from lead poisoning in rabbits. Urinary lead excretion was markedly increased after the first doses of BAL, but the magnitude of the excretion response diminished with additional treatments. Apparently only a small portion of the stared lead can be removed by this treatment. The im plications with respect to the possible use of BAL in the treatment of lead poisoning in man are discussed. 890 Acute Toxicity of Arsenate of Lead in Animals. J.L. Voigt, L.D. Edwards and C.H. Johnson. J. Am. Pharm. Assoc., Sci. Ed., 122-123 (191*8) The acute toxicity of arsenate of lead in chickens, white rats, ani rabbits was studied. The oral LDcq for a single dose was found to be approxi mately 1*50 mg. per kg. for chickens, 825 mg. per kg. for white rats, and 125 mg. per kg. for rabbits. The data included the red cell count and change in weight in chickens after feeding 500 mg. per kg. of arsenate of lead. -- Chem. Absts.