Document wqLzpNbRrxLaJJ6n5JzdvQ9GQ
BRADLEY & MERRELL C /O JONES, JONES, CLOSE & BROWN, CHARTERED
Seventh Floor -- Bank of America Plaza 300 South Fourth Street
Las Vegas, Nevada 89101-6026 (702) 385-4202
MESSAGE FROM XEROX 7024: (7021 385-1655
DATE:
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TO: Sue Fogleboch
FAX # : j (702) 367-5629
PH O N E#: (702)367-5632
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CLIENT/MATTER:
Nevada Power v. Monsanto
CUENT/MATTER NO.: 11927.2
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BRADLEY & MERRELL c/o JONES, JONES, CLOSE & BROWN, CHARTERED
seventh Floor --Bank of America Plaza 300 South Fourth Stroat
L u Vagaa, Nevada 891O1*SO20
(702) 380-4202
MEBSAOE FROM x e r o x 7024: (7P2) 335^1555 DATE: A M j 2 4 . 1 < W 3 _______________ I
TO: Sue Fogleboah
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(702) 1367-5320
PHONE iV: (702) 367-5S32
FROM:
CUEMT/MATTEH;
Nevada Power v. Monsanto
CUENT/MATTER NO. 11B27.2
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MEMORANDUM
John H. Kim, Esq. Roberta Straub, Esq.T^K Dr. Peterson Expert Statement July 27 , 1993
Under cover of this memo, you will find a 26(b) (4) expert witness disclosure statement for Dr. Richard E. Peterson. This is only a draft, but I do not anticipate any major changes to it. Any changes that must be made will probably be merely in form, but not in content.
Would you please check to see if this statement dovetails with what Dr. Arnold Schecter is expected to testify on? If there is no statement as of yet for Dr. Schecter, will you please let me know as soon as possible? I will then contact him and begin working with him to formulate his statement. Thanks, John.
In addition, I am working on statements for the other experts identified for this case. I hope I am not duplicating efforts with your office. To that end, would you please let me know what has been accomplished with the experts?
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Nevada Power v. Monsanto Co., et al. Case No, A275863
PRETRIAL WITNESS STATEMENT
Richard E. Peterson, Ph.D. Toxicology Consultants, Inc. 5202 Denton Place Madison, WI 53711
SUMMARY OF TESTIMONY
Dr. Peterson is Professor of Pharmacology and Toxicology in
the School of Pharmacy and Environmental Toxicology Center at the
University of Wisconsin. Dr. Peterson has published extensively in
the area of halogenated aromatic hydrocarbon toxicity.
Investigations in his laboratory have used polychlorinated
biphenyls (PCBs), dibenzo furans (PCDFs) and dibenzo-p-dioxins
(PCDDs) and have involved different mammalian, avian and aquatic
species.
Bioaccumulation, metabolism and disposition, acute
toxicity, reproductive and developmental toxicity, and
neurotoxicity have been assessed. Signs of toxicity, dose response
relationships, time course of toxicity, sites and mechanisms of
action, and risk have also been evaluated. Dr. Peterson is a
member of the Society of Toxicology and Society of Environmental
Toxicology and Chemistry. Results of his laboratory's research are
presented at annual meetings of these societies. Industry and
state and federal agencies have used Dr. Peterson's expertise in
halogenated aromatic hydrocarbon toxicity.
Dr. Peterson is presented as an expert on the toxicology of PCBs and related compounds that act by Ah receptor "-dependent" and "-independent" mechanisms of action. He will testify on the basis of his education, training, research experience, understanding of the current literature, review of state of the art research and reports generated by that research on PCBs, PCDFs and PCDDs. He will testify on PCB toxicity in humans and animals including mechanisms of action, structure activity relationships or Ah receptor-mediated toxicity, metabolism and disposition, and the various signs of toxicity. He will testify on fundamental aspects of risk characterization such as exposure assessment, hazard identification, dose response assessment, and reference does concept. He will testify that humans and animals have similar
sensitivity to Ah receptor-mediated toxicity and that PCB congeners that share the same Ah receptor-medicated mechanism of action as TCDD (TCDD^like PCB congeners) need to be considered together with TCDD in assessing risk to humans and wildlife.!
Dr. Peterson will testify that early life stages (embryo or
fetus) are more susceptible than adults to Ah receptor-mediated
toxicity and that exposure during criticalj periods of early
development can produce functional alterations in adulthood that
may be irreversible.,
Dr. Peterson will! testify that the
background human body burden of TCDD equivalents due to the TCDD-
like PCBs, PCDDs and PCDFs does not provide ari adequate margin of
safety for certain reproductive, developmental\ or rieurobehavioral
toxicities that results from in utero and/or lctational exposure.
Dr. Peterson will testify that PCBs are inherently and
unreasonably dangerous and that inputs of PCBs into the environment
must be reduced to lower the existing background human body burden
of TCDD equivalents. He will also testify that PCB-containing PCB
equipment at Nevada Power which is above as well a s 1below existing
EPA standards is defectively hazardous because bioaccumulation of
TCDD-like PCBs from such equipment will contribute further to this
already high body burden.
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f Dr. Peterson will rely on the general scientific literature on
PCBs, PCDDs and PCDFs as well as on publications from his own
laboratory research. He will also review recent EPA publications,
relevant publications provided by other federal and state agencies,
and symposia and book chapters dealing with lialogenated aromatic
hydrocarbon toxicity. At the request of the plPainti!ff "s lawyers he
will review learned treatises of other experts or any other
documents related to the case which they will|provide.
Dr. Peterson may also be called on to explain and define any scientific terms used by the defendants in documents gathered by Nevada Power during discovery, and presented to him.
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