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PROCEEDINGS FIBROUS DUST SEMINAR November 22,1968 j INDUSTRIAL HYGIENE FOUNDATION OF AMERICA 5231 CENTRE AVENUE PITTSr'JrG.*; USEI000138 PROCEEDINGS FIBROUS DUST SEMINAR November 22, 1968 Mellon Institute of Carnegie-Mellon University Pittsburgh, Pennsylvania Medical Series: Bulletin No. 16-70 Industrial Hygiene Foundation of Anr,erica, Inc. 6231 Centre Avenue Pittsburgh, Pennsylvania 15232 Copyright 1 970 Industrial Hygiene Foundation of America, Inc. USEI000139 PREFACE This Fibrous Dust Seminar represents an important step towards fulfillment of the first goal in which direction industry should be moving according to Dr. Theodore Hatch, IHF Trustee Emeritus, in Industrial Hvglene Highlights - Vol. 1---i. e. , protection of employee health. These proceedings exemplify industry's attempts with IHF's help to advance scientific progress by use of epidemiological and biostatistical studies, in plant as well as in the experimental research laboratory. Studies on fibrous glass, which appears to have no demonstrable pathogenic effects, provide an effective control over those investigations on asbestos bioeffects reported herein, all of which have been performed in or for IHF. It can be seen that studies designed to investigate patho genic effect become highly sophisticated in an attempt to prove the "null hypothesis. " These studies of fibrous dusts are still under way and further progress will be reported as it developes in an effort to keep our members and the interested scientific and professional communities advised. The use of fibrous dusts is so widespread today that all those responsible for employee health should find this bulletin interesting and useful. Robert T. P. deTreville, M. D. , Sc. D. President m. USEI000140 Preku TABLE OF CONTENTS ................................. .. ........................................................................................ Robert T. P. deTreville. M. D. President Industrial Hygiene Foundation Page iii Welc om Robert T.. P. deTreville. M. D. and G. A. Webb, Ph. D. , Chairman IHF Board of Trustees Associate Director, Mellon Institute Carnegie-Mellon University Opening Remarks........................................................................................................... W. Clark Cooper, M. D, Professor in Residence Occupational Health School of Public Health University of California (Berkeley) IHF Statistical Studies of Health of Fibrous Glass Workers .............................................................................................. H. Michael D. Utidjian. X.. D. Assistant Professor Department of Epidemiology Graduate School of Public Health University of Pittsburgh Records Studies of Health of Fibrous Glass Workers ................................................ ...................................... ^0 Lewis J. Crallev. Ph. D. Scientist Director. Associate Chief Occ. Health Program, Field Studies U. S. Public Health Service A Comparison of the Effects in Experimental Animals of Certain Fibrous Dusts: Fibrous Glass --Asbestos (Natural and Synthetic).................... 22 Paul Gross, M. D. . Director IHF Research Laboratory Physiological Studies of Health of Fibrous Glass Workers.............................................................................................. Benjamin J. Lambiotte, M. D. IHF Resident Fellow in 26 Occupational Medicine Radiological Studies of Health of Fibrous Glass Workers ...................................................................................... Jon L. Konzen, M. D. 23 Medical Director Owens-Corning Fiberglas Corporation iv. USEI000I41 TABLE OF CONTENTS Moderator's Summarization (Morning Session) ... ........................................................................... *......................... W. Clark Cooper, M. D. 39 Opening Remarks .............................................................................................................. 41 Lewis J. Cralley, Ph. D. Asbestos Exposure in the U. S. Textile Industry--1930 to Date................................................................................... Joseph L. Goodman, M. D. Medical Director for Research Raybestos-Manhattan, Inc. 42 Statistical Studies of U. S. Asbestos Products Workers ............................................................................................................ Philip E. Enterline, Ph. D. Professor of Biostatistics Graduate School of Public Health University of Pittsburgh 32 Studies on the Pathogenicity of Brake Drum Dust................................................................................................. .. Paul Gross, M. D. 60 Pathological Studies of Ferruginous Bodies: Methodology ..................................................... ............................................... H. Michael D. Utidjian, M. D. 33 Pathological Studies of Ferruginous Bodies: Instrumental on................................................................................................ Martin N. Haller Fellow, Mellon Institute Carnegie-Mellon University 6c Pathological Studies of Ferruginous Bodies: Bodies: Basic Consideration^.................................................................................... John M. G. Davis Department of Pathology University of Cambridge 69 Discussion Paul Gross, M. D. <D Concluding Remarks ......................................................................... I ( Robert T. P. deTreville, M. D. v. USEI000142