Document wq1vwJ908qwG3X9y7VM5pwkp4

NOV-06-2002 WED 04:26 PM SHEPARD HOFFMAN ESQ FAX NO. 2145220420 P. 16 u i PULMONARY ASBESTOSIS III: CARCINOMA OF LUNG IN ASBESTO-SILICOSIS KENNETH M. LYNCH, M.D., and W. ATMAB SMITH, MJX {From the Departments of Pathology and Medicine, Medical College of the State of Sovth Carolina) Primary carcinoma of the lung has attained a position of major in terest in malignant neoplastic disease, through at least a more common recognition, if not more frequent occurrence, within recent years. Likewise asbostosis has assumed a rank of considerable importance in industrial medicine. Workers in the mines of the Era Mountains, on both the Bohemian and the Saxon sides, have suffered heavily for some centuries from pul monary disease now reeognizod as carcinoma and woll known as Schneeberg and Jdchymov (Joachimstal) lung cancer. Pirchan and Sikl (1), in a report upon a series of these cases, state that "there wore only moderate degreos of anthracosis," and they.are not inclined to attach any particular importance to the degree of pnoumonoconiosis as a cause of the cancor, but consider that "the question may be somewhat different with regard to the quality of the foreign substance deposited in the lung." Chemical analysis in one of their cases revealed "only calcium, magnesium, aluminum, silicic acid, chlo rides, and phosphates; no trace of arsenic, bismuth, cobalt, nickel, or uranium was found." They lay suspicion, as others have done, upon radium emanation and upon arsenic, both factors being encountered in the Schneeberg and Jachymov minos. Rostoski, Saupo and Schmorl (2) found sovero "anthracosis" in Schneeberg minors the subjects of lung cancer and are inclined to at tribute tho causation of the cancer to the anthracosis, while Simpson (3) states that pulmonary cancer is a rare complication of silicosis in South African miners. Schulte (4) has reported lung cancer in pneumonoconiosis among coal minors, and Saupe (5) has recorded two cases in arsenic minors. There appears to be no previous report of its oc currence in asbestos miners or mill workers, although the record of autopsy examinations of cases of asbostosis is not large. As worthy of record in tho interest of both diseases, as well as their possible relationship, the following case of pulmonary asbostosis with associated carcinoma of the lung is reported. Case Rispobt A white man, fifty-seven years of age at tho time of his death, first came under observation at the Shirras Dispensary of tho Roper Hos pital on Jan. 10, 1934, at which time he appeared very old, weak, and 56