Document wgkKQ7xGxp07vddeZz5o1OBmo

NOV-06-2002 WED 04:28 PM SHEPARD HOFFMAN ESQ FAX NO. 2145220420 P. 24 64 KENNETH M. LYNCH AND W. ATMAK SMITH Summary This man had suffered long occupational exposure to dust, some forty-three years all told, about twenty-two in a cotton mill, about twenty-one in an asbestos factory, with resulting fibrosis of extensive grade in the lungs and pleura, the apparent consequences being pul monary circulatory and respiratory disability, with emphysema, bron chiectasis, and cardiac embarrassment. As has been observed by us in other cases of asbestosis, one of which has boon previously reported (6), the fibrosis of the lungs here bears the accepted characteristic mark of silicosis, that is, in addition to diffused fibrosis, there occurred the formation of hyalino fibrous nodules. The pulmonary carcinoma appeared to originate from ono of the branches of the bronchus to the right lower lobe, where squamous meta plasia of lining epithelium was observed. . The duration of the carcinoma cannot be specified. It was appar ently of considerable time but cortainly did not antedate fibrosis of the lung. A conception of its origin by reason of chronic bronchial irrita tion is compatible with the current view of the etiology of such tumors. Reperidncbs 1. Piuohan, A.,'and Sikl, H.: Cancer of the Jung in the miners of Jdchymov (Jonchimstaj): Report of cases observed in 1929-30, Am. J. Cancer 16: 681, 1932. 2. Roaro8Ki, Saupe, and Scjimokd: Die Bergkrankheit der Erzberglcute in Sclmeeberg in Sachsen (" Schneebcrger Lungenkrebs "), Ztschr. f. Krebsforsch. 23: 360, 1926. 3. Simpson, S. L.: Primary carcinoma of the lung, Quart. J. Med. 22: 413, 1929. 4. Soholtb, G.: Pnevunokonioaen der ltuhTberglente und Lungenkarzinom, Fortsohr. a d. Gob. d. Roentgcnstrahlen 41: 444, 1930. 5. Saupe, E.: Carcinoma of the Jung in arsenic miners: two cases. Arch. f. Gowerbepath. u. Gowerbehyg. 1: 682, 1030. 6. Lynoh, K. M., and Smith, W. A.' Pulmonary asbestosis II, including the report of a pure case, Am. Rev. Tuberc. 23 : 643,1931. LY3 (Ft dition to rep Th her adz in the * of brea appotib nothing Th were cc ocular wore n< The tor were si hard, brownii No othi what ei . Th veins oi Tho liv firm ma of the quadra) mass wl movabli Th. tion, oi equal ai Th. nogativ. red bloc Th. The difl leukoey On they wt perforn mosonte of bloo