Document wg0rDZzRD3eedrZ8Q1GZL4ka4

FILE NAME Brakes BRK DATE 1976 Dec DOC BRK065 DOCUMENT DESCRIPTION Conference Report - IARC Monograms on the Evaluation of the Carcinogenic Risk of Chemicals to Man Asbestos IARC MONOGRAPHS ON THE EVALUATION OF THE CARCINOGENIC RISK OF CHEMICALS TO MAN Asbestos Volume 14 This Evaluation publication represents the views of an IARC Working Group on the of the Carcinogenic Risk of Chemicals to which met in Lyon 14-17 December 1976 Man oY etAIL PRae . 1 Phin rey le j ts t : ee ae Es ! i a = 1 * i 5 , ee ones 2% . 4 z : i H cant om ot, re? 4 1 , ae aa it ' F agh . x a = 3 gt a Pa * + eS fs aay es Le d a : itt 3: ro a 2. ae, coe + 4 ay \ , ; : fe9 Rees Ca eg RE et roe ge ee * Roy awe. > TT ES TE IT Biles & Emerson 1968 and Cunningham & Pontefract 1971 also reported the occurrence of asbestos fibres in British Canadian and American beer 1-6.6 million fibres Asbestos fibres were found in various sherries ports vermouths and soft drinks 1.7-12.2 million fibres Cunningham & Pontefract 1971 Pharmaceuticals Chrysotile asbestos has been found in some samples of parenteral drugs range 1-1000 ng Nicholson et al 1972 In the US no containing or other releasing filter may be used in the manufacture processing or packaging of such products unless it is not possible to manufacture that drug product or component without the use of such a filter US Food and Drug Administration 1976 Dental practice and dental school laboratories containing periodontal packs are sometimes used after gingival surgery Infante & Lemen 1976 In dental schools asbestos tape is used to hold gold that is heated and then cast into moulds during dental laboratory procedures This may be a potential problem and has not been evaluated by adequate industrial hygiene monitoring b Asbestos in the work environment Asbestos contamination of the air can be caused by spraying of asbestos material either for fire protection or for decorative or acoustical purposes contamination was found to be high during the application of sprayed mineral fibre Nicholson & Pundsack 1973 A comparison of asbestos concentrations in air under different circumstances as measured by electron microscopy is as follows near asbestos spraying 10-1000 mduring a milling operation 10-5000 m in other occupational exposures 1000- 100,000 mNicholson et al 1975 Fibre concentrations in various asbestos industries in the US prior to 1971 as determinebdy optical and electron microscopy are given in Table 11 36 sae ees eee RSG FB BM eb ie er * 4, Age Ree a t Table 11 : Concentrations of fibres in various asbestos industries 2 in US before 1971" ; Industry : : ? 3 Textile Insulation Range of means fibres > 5 ml 0.1-29.9 0.1-74.4 Range of individual samples fibres > 5 m 0.0-143.9 0.0-208.4 : Paper packing and asphalt ; production Cement shingles millboard and gasket Friction Cement pipe 0.2-13.6 0.1-4.4 0.1-14.4 0.2-6.3 0.0-18.9 0.0-16.6 0.1-32.4 0.0-13.4 a From US Department of Health Education & Welfare 1972b Airborne asbestos sampling programmes do not at present however attempt to discriminate between the various fibrous minerals present in dust samples Table 12 gives a comparison of the length distributions of airborne asbestos fibres as determined by electron miscroscopy in various industries in the US : Table 13 gives the contentosf asbestos fibrebsy products and fibre type in asbestos products produced in various EEC countries Occupational exposure in situations other than the traditional asbestos processes mining milling factory production and handling of asbestos products has been shown to be of increasing importance Such exposures occur during product use as among asbestos insulation workers Selikoff et al 1964 among brake repair and brake maintenance workers Lorimer et al 1976 Rohl et al 1976 1977 and as the result of indirect occupational exposures particularly in ship building and ship repair Harries 1968 1976 and in the construction industry Other exposures occur in relation to inspection repair and maintenance work on containing strictures and Table 12 Lengths of asbestos fibres in air near various US industries - Operation Fibre type Median length ...m 8 > 5 ...m Textile chrysotile Fibre preparation & carding Spinning twisting weaving 1.4 4 1.0 12 Friction Mixing chrysotile Finishing 0.9 22 0.8 22 ioe Mixing el, Asbestos pipe chrysotile chrysotile Finishing 0.9 2 0.7 1 Pipe insulation Pipe forming <anth amosite 4.9 51 ad a From Dement et al 1976 es caeallan equipment in refineries and chemical plants buildings railway locomotives and wagons shipyards and power plants Increasingly importart exposures can be expected to result from building demolition and waste disposal US Environmental a considerable problem in Protection Agency 1975 These view of the very large amount of could pose asbestos now in place as the result of the cumulative use of the material during the past century Exposures may also occur during the wearing of asbestos safety garments Gibbs 1975 during cleaning operations on buildings formerly sprayed with asbestos Skidmore & Jones 1975 and during of raw the handling of bags formerly used in the transport or milled asbestos US Department of Labor 1975 . and storage c Domestic exposure workmen Domestic exposure of household contacts to asbestos may occur from dusts brought home on workers clothes shoes hair equipment etc. Anderson et al , 1976 Newhouse & Thompson 1965 Wagner et al 1960 Nicholson et al 1975 found asbestos reels reels tanging frURL 100-500 min the houses of 38 ii a Asbx : Firs , J01 F F TH 2, F M Fiid ; an , exros aie ia hea * mayy mairi