Document wKNjNGNxj7LzjQqj7VjELvRq6

\ - J*, **- . ir> sr-'-Ti -Study of the AabetjT^pduete Mapufauturing-Iadustey^-^ United Stales MOt * R^?'FROM Xevris J. Cralley a \\AC. - qP Ny \ n^' Division of Occuneticnal -H--e-a--lt-h--. - \HDUsr^X pV^HO1 B Bureau of Disease Prevention and Environmental Ccafcol s f'USffiS'' < ppG Ujr Rills HttltS Service - Department of Health, Education, sad Welfare f Cincinnati,' Ohio 45202 *tt? ' f fj The Division of Occupational Health, Public Health Service, has underway n p* * *. *. an extensive epidemiologic study of the asbestos products manufacturing industey - in the United States. * ^,i;' r ```/".'T H'f) V i- , Purrcs* of Siudv ' ' y .- -:OC ,r;i CQ. , wi V/ i \ * L- i . t w' 1i 5 j ^ J * t.0 r ** The study is designed to (a) obtain information on the health effects of V * e * *4 f exposure to the major types of asbestos used in the United States (ehrysotHe, rt. * i-i erccidolite, and amosite), (b) develop criteria for safe exposure levels, and V?1 ' (c) e5teblish medical and environmental criteria for surveillance where asbestos d * ** * H is encountered or used. 5] Seen* of Stadv - 1l Baseline and longitudinal studies will be done on approximately ID, 000 rJ 4 werkers employed in the following asbestos products manufacturing areas; (a) asbestos textile materials, (b) asbestos insulating materials, (c) asbestos friction materials, and (d) asbestos cement building materials including asbestos cement piping. * V. " Comparative cohorts, approximately 2,500 in each group, will be 1 constructed from each of the four product manufacturing groups on which i -* i baseline in-plant environmental exposure data will fee obtained, along with t personnel dateeharaeterixieg each individual in the cohorts. In addl<"" , ,, `v | BB 0023549 available retreepeutiv cxv-U*:M*tel expnvura date, similar prospc""r-TTr~~**" Jcutfenr comeRfrw -2 iNflUSTWES, INC. _ w?T5 be adtkd ta the e *%, .i4%.2**m* UH j-; \ ;.j ., --* 4 wt "*-V* *i . ?*-?- will be obtained through baseline and follow-up examination* on a ,* * * ** substantial group within each cohort for clinical evaluation of the worker* during the period of the study. ' Individuals in the four cohort groups, including those who mzy have left * the industry, will he followed until appreciable periods of exposure, 25 years ri < ^V-lj rrW*. M! J: .a i _t f* ** -tv i and longer, as well as latent periods from time of first e^osure have been covered. Through records of the Bureau esff*^(W$ldd AAg-ea nd Burrfvor's " 1" DiD ath certificaies-will be located on those in tho cohorts -on whom beneflt'-claims have been made. Copies cf the death certificates will be obtained from the respective * state departments cf health, evidence confirming causes of death will be studied, # arc specific aortalityraies established. Tnese data, along with environmental exposure, clinical and other data characterizing individuals in the c horts, wtH be studied to establish trends and relationships; i , # Baseline In-plant Data on Cohorts The entire in-plant employment of each participating plant will be included i * la constructing the four cohorts of workers. The following'information will be ebtained os each individual; (a) identifying Information, including date and place of birth, sex, places.;! residence, aad-soelal security number, (b) work 3 4 history before and since entering the*industry, (c) job classification and . % i 4844 description, (d) smoking history, and (c) hobbies.___ ________ I BB 0023550 J nr t3is DOCUMENT WAS NOT A REC&fiPT^F me.p3g INDUSTRIES, DID NOT COME FROM n|s FILES AND CANNOT BE AUTHENTICATED - -3 - * > f ^ PP- INDUSTRIES, j^Vjroa2aeataji it obtained characterizing in detail the nature and . extent of in-plant exposures for each worker included in the study. Special ?i ' ;1 r attention will be given to assessing exposures to asbestos fibers, including * different parameters of measurements such*is total particulate count, liber .1 * * * count, respirable mass, etc. la addition, other associated exposures such as *i * i metals, silica, specific polycyclic aromatic compounds, xnd radioactivity *3 - levels will be assessed. 3 * Medical studies will be made to define the health status ard mend in the ' J cohorts throughout the study. Tae nature and design of these stidies will c.: u j' 0 * 4H evolve fretn the recommendaticns of the medical consultants to the study. * * ,, 4 ** ,' ^ Since the entire in-plant employment of the.parUcipating plants will, beV induced in the study, the range ef exposure levels will permit those with minimal exposure to serve as cn internal control group. Controls will also 3i be. drawn Jrora other en-geing studies by the Division. Stands of Studv * C` . Environmental studies were started during the early part of 1353. To"_ 4 < J*ut*4 * . dale baseline environmental and personnel data have been collected on over . `1f 7, 000 workers in the four groups. This phase of the stify 'should be completed *% # 1 -} by the fall of 1967. .1 4 Medical studies on workers in the cohorts are anticipated to start during 3. * the latter part of 1967. In the meantime, a panel of roentgenologists Is drawing up a scheme for reading the films cf asbestos workers. A contact is also f n underway to design the pulmonary function tests to be used. 4245 % i _l ^B^00235s"l~7 * data will Le obtained characterizing in detail the aateera and * iant exposures for each worker included in the study. Special Z' be given to assessing exposures to asbestos libers, including * 0 ameiers of measurements such"as total particulate count, fiber .rsile mass, etc. In addition, other associated exposures such as ica., specific polycyclic aromatic compounds, and radioactivity be assessed. ical studies will be made to define the heslth status and trend in the ' moughout the study. Tae nature and design of these studies will . css the recommendaticns of the medical consultants to the study, ^ j' ^ sc^pst entire in-plant employment of the participating plants wiH.be!. . in the study, the range of exposure levels will permit those with y - 1 exposure to serve as an internal control group. Controls will also ^ *n from other on-going studies by the Division, ^ e* :dv l,/_ Environmental studies were started during the early part of 1S53. To-"/. ; J caselinc environmental and personnel data have been collected on over e. 0 workers in the four groups. This phase of the study should be completed y are being analysed ic '. eg from lung cancer, ' n exposures to metals * ,,% i* at,*- with and without i sials wCl be sought 5 strels from the same \ sues, their specific \ A * t 0 i ope program is __* \i fibers of vegetable, 7m from industrial, ,'rsonal nctivitien, ximataly 10,000 oducts and t -51 and have : s. ae fell of IS 67. Medical studies on workers in the cohorts are anticipated to start during latter part of 1967. In the meantime, a panel of roentgenologists Is drawing j^lheme for rending the films cf asbestos workers. A contract is also f idenvay to design the pulmonary function tests tc be used. ** 4S45 J?EC0R0PPG^INDUST^ff!ls*IN^^DJD^MOr of 7"8b"o02355"7 --------------------------------- 424S AS-*--