Document vy6kLejyEkKLV53EKB8VkRmDb

FLA1N11* November 20, 1936 LeRoy U. Gardner, II. D., Director, The Saranac Laboratory, ' Saranac Laice, New York. Door Dr. Gardner: At a meeting yesterday attended by certain hrane lining manufacturers, iir. Simpson and I were able to present to a fairly large group of interested corporations the proposal that one of your duatlng chambers be engaged far further experi--,, mentation with asbestos dust. ' The proposal was very well received and It appears that not less than eight, and perhaps ten or more, corporations .11 participate in financing these further experiments along vhe lines diocussed when we met with Dr. Lanza and Dr. McConnell a fc-w days ago. Accordingly, you may consider tliis letter as an authorization to you to cormaonce the contemplated experiments with asbestos dust for the purpose of determining more definitely the causes and effects of nsbestosis. It is my understanding that, among other questions which it is anticipated theso experi ments will answer, are the following! (1) VVhat concentration of duot is necessary to prouuce the fibrosis of the lungs which la designated as . asbestosls. (2) Whether exposure to asbestos dust will produce asbestosls without the oxistence of previous infection and whethor the X-rny changes found In advancod human asbestosls can be reproduced in animals without infection. (3) Whether tho fibrosis produced by asbestos is of the progressIyq typo, that 13, will the fibrosis increase (onco it has started) after exposure to the duot has censed.