Document vV3GJYbxn4pqRNoK1XXnnE5RY

i Z -45 R C V I* 79 E. ] . IMAILrtHlOlO: du Pont de N emours & C om pany IN C O R P O R A T E D W i l m in g t o n . D e l a w a r e 19898 POLYMER PRODUCTS DEPARTMENT E X P E R I M E N T A L S T A T ION PERSONAL AND CONFIDENTIAL cc: A. J. Dahl B. W. Karrh L. J. Papa Pral File 1 .C. - 353 - XI1400 - 269 / 4>02~ September 29, 1981 TO: DR. X. L. POWER - PPD, Parkersburg FROH: S. S. STAFFORD ANALYSIS OF BLOOD SAMPLES FOR PERFLUOROOCTANOATE (Job No. S10-578; PRAL Nos. 81-3918-3970; Notebook Nos. E22514,E26238) As requested in your letter of 8/25/81 to L. J. Papas the 53 blood samples submitted then have been analyzed for perfluorooctanoate (CD) by the usual gas O chromatographic method ES-567. Results and sample identification are given in the attached table. Attachment jab Key Words: Perfluorooc tanoat e GC Blood Analysis There's a world of thin gs we're doing som ething about O u O a c .l EXP000055 EID713869 TABLE I CONCENTRATION OF PERFLU PRO OCTAN OATE IK BLOOD (a) Sample PRAL No. Date Sampled 31-3918 81-3919 81-3920 8/11/81 8/11/81 8/11/81 81-3921 8/11/81 81-3922 8/11/81 81-3923 81-3924 S/ll/81 8/11/81 31-3925 8/11/81 81-3926 81-3927 8/12/81 8/12/81 81-3928 8/12/81 81-3929 81-3930 8/12/81 8/12/81 81-3931 81-3932 8/12/81 8/12/81 81-3933 81-3934 81-3935 81-3936 81-3937 8/12/81 8/12/81 8/12/81 8/12/81 8/12/81 81-3938 8/13/31 81-3939 81-3940 81-3941 81-3942 81-3943 81-3944 81-3945 81-3946 81-3947 81-3948 81-3949 81-3950 81-3951 8/13/81 8/13/81 8/13/31 8/13/81 8/14/81 8/17/81 8/17/01 8/17/81 8/18/81 8/18/81 8/18/81 8/18/81 8/S8/81 F.R.No 4109 4227 W.S. 4177 W.S. W.S. W.S. 4449 4631 W.S. 4151 4316 867 W.S. 4248 W.S. 4432 4264 916 1898 3562 1743 4549 1792 W.S. W.S. 3204(d 4448 4650 4747 4518 3467 W.S. W.S. Name GC Analysis Date Analyzed 9/10/31 jcaL..V...J 0.17 9/10/81 0.075 9/10/81 0.092 9/10/81 0.21 9/15/81 0.026 9/11/81 0.093 9/11/81 0.23 9/11/81 0.042 9/11/81 0.12 9/11/81 0.086 8/31 8 9/1/81 0.98 9/14/81 0.78 9/11/8 L 0.24 9/11/81 0.053 9/23/81 6.9 9/11 & 9/15/81 0.041 9/14/81 0.52 9/14/81 9/14/81 0.41 0.34 9/14/81 0.092 9/14/81 0.79 8/31 & 9/1/81 1.2 9/14/31 0.92 9/15/81 0.33 8/31 & 9/1/61 2.6 9/16/81 1.1 9/15/81 0.25 9/15/81 0.091 9/22/81 9/15/81 9/21/81 0.019 0.090 1.6 9/15/81 9/15/81 0.078 0.40 9/16/81 0.70 (b) *REDACTED* 000149 EXP000056 EID713870 TABLE I CONCENTRATION OF fERFLEOROOCTANOATE IN BLOOD (a) Sample PRAL No. Date Sampled 81-3952 31-3953 81-395A 81-3955 81-3956 81-3957 81-3958 31-3959 8/18/81 8/19/31 8/19/81 8/19/81 8/19/81 8/20/81 8/20/81 8/20/31 81-3960 31-3961 31-3962 8/21/81 8/21/81 8/21/81 81-3963 81-3964 81-3965 81-3966 31-3967 81-3963 8/24/81 8/24/81 8/24/81 8/2A/31 8/2A/81 S/24/81 81-3969 81-3970 8/24/81 0/24/81 P.R.No. Kme W.S. 424 2 4553 290 3574 W.S. 4334 1529 4746 3325 4664 4624 4299 4551 W.S. 4300 3661 4009 W.S. I GC Analysis Date Analyzed ICr ]., _v.g : 9/16/81 9/16/81 8/31 6 9/1/81 9/17/81 9/18/81 9/16/81 9/18/81 9/18/81 9/17/81 9/18/81 9/17/81 9/16/81 8/31 & 9/1/81 8/31 6, 9/1/81 9/18/81 8/31 & 9/1/81 9/18/81 9/18/81 9/18/81 0.19 0.29 3.5 0.077 0.52 0.29 0.43 0.76 < 0.007 0.63 0.076 0.39 A.2 1.5 2.A 2.0 0.15 1.2 0.15 _(b oo 81-1461 4/7/81 4299 1 3/31 6 9/1/31 A.5(c) (a) Analysis as descr ibed in Lab Acid in Blood, Gas Chromatographic Method", S. Stafford, A/3/81), using the packed column GC analysis with perfluoro-n-octanoic acid as calibration standard. (b) Although the analysis is specifically for perfluorooctanoate (acid or salts), concentrations are given in ppm fluorine for comparison with the results of total organic fluorine analyses. (ppm F = 0.688 x ppm perfluorooctanoic acid) Estimated uncertainty is + 10% relative standard deviation. The lower limit for quantitation is 0.007 WgF/g. The detection limit is 'u 0.00A pgF/g, but concentrations in that range cannot be well quantitated and are reported as < 0.007. None detected (n.d.) is reported for samples with |Cg] / O.OOA ppm, which cannot be distinguished from reagent background. (c) Previously analyzed sample, reanalyzed for comparison with repent sample 81-396A; result of the initial analysis (A/2A/81) was A.5. (d) P.R. Number given as 32A0 on the sample tube. *REDACTED* OOOlbo EXPO00057 EID713871