Document vBpXR9mB5Dz5XpLwo4oyqNXbY

ATTACHMENT TO LETTER TO C. AUER DATED AUGUST 31, 2000 SUPPLEMENTAL SUBMISSION PFOA Perfluorooctanoic acid Medical Surveillance and Epidemiologic SSeeeveirteaml Fl1uuonrodcehrePmFiOcaSl:s,InJtuenriem8,R2e0p0o0r.t #1, Determination of Serum Half-Lives of Acute Toxicity 1. FSsoitnuliaddlysR-NeoCp.o7HHrt,L15AACcO9u1Ote2-0NO1rH7a34l+9T,,o23x.2Mi%ciRtyheofSmetruoednlyocgeisnN,R5oa0.t%Ts,-w4H4aa1tze6lre,(tao2pn.5pL%roaxbiniomerraattstoe)r,liyeAs4p5Ar%ilm2eF,rCi1c-9a19,403. 2. FGRieunfiaedlreeRlniencpeeos)Nr,t,oH.PaTrzi-ml4e4ator1yn6,DLFaeebrmborraualatorIyrrriei1tsa4t,Aio1mn9/e9Cr0io.crar,oSsitoundySNtuod.yHinLARa9b1b2it0s1(7O4E0,C3DM 3. FH44ian1za6lle,RtFoeenpboLruratab,roPyrra2imt8o,rair1ey9s9EA0y.meeIrrircitaa,tiSotnu/dCyoNrroo.siHonLASt9u1d2y0i1n7R4a0b, b3iMts (ROeEfeCreDncGeuNidoe.liTn-es), Genotoxicity 1. F4C3ihn7ian,le3RsMeepHRoaermtf,esrMteenurctOaegvNeanori.ycTi(tC-y6H3TO5e8s)t,CoFenCll-Ts1,-46C33,o5mL8oiMnt g3e3aHs2au,zrAienlpgtroinCl 2hI5nro,cm.1, 9oS9st6ou,mdwyailNthAo.pbre1or7rt3oa8tcio8ol-n.0sin 2. FCLioontma3li3nR2ge,pHMoarazty,leM1to4un,ta1Ign9ec9n.6,i,cSwittuyitdhTypeNsrototo.on1co7Tl3-86a38n5-d08p-4rino5t5ao,nc3oIMlnaVRmievefonedrMemnoecunestesN.Mo.iTcr-o6n3u5c8l,euFsCA-1s4s3a,y, Pharmacokinetics SubmittPbAeyrdnoDtaIenbeivonaev,nsentthaiuegnJsa.idtsiNeorsanuPbboFbmfeOftiShettle:eddE, Aftofeptcrhitlse 1oG9fr9Fa8dluuoartoecSacrbhooonls oofnthLeivUerniFvaetrtsyitAycoidf-MBiinnndeinsgota, Ongoing 1. MWeacllhaacneisinticcluredseesaPrcFhOaAt ,th3eMURnievfeerrseintyceoNf Mo.iTnn-6e8so8t9a.1u.ndDeorctuhme denirtescrteiognarodfinKgetnhdisall 10 ATTACHMENT TO LETTER TO C. AUER DATED AUGUST 31,2000 SUPPLEMENTAL SUBMISSION research have been previously submitted with the May 4, 2000 submission on PFOS (see Mechanistic 1)(a)-(f))- 11