Document vBBBdKr4O7b0QLDyE0ve1Okeb
MANUFACTURING CHEMISTS ASSOCIATION
1825 CONNECTICUT AVENUE, N.W. WASHINGTON, D.C. 20009 (202) 483-6126
CHEMICALS RESEARCH
APR2Q 1978
April 17, 1978
TO :
Vinyl Chloride Technical Panel Vinyl Chloride Research Coordinators
SUBJECTS:
Liver Angiosarcoma Registry, Dr. J. Stafford, Division Manager, Health and Environment Protection, Imperial Chemical Industries Limited, Plastics Division (Two Documents)
LM
Angiosarcoma of the Liver: An Epidemiologic Survey, by Judith Brady, et. al.
Vinyl Chloride: A Case for the Use of Laboratory Bioassay in the Regulatory Control Procedure, by J. K. Wagoner and P. F. Infante
Abstracts or Papers for the Seventh Annual Meeting of*the Society of Toxicology, San Francisco, California, March 12-16, 1978: The Effect of Disulfiram on Vinyl Chloride Induced Carcinogenesis in Mice, by J. M. Winston, et. al.
Gentlemen:
Dr. Torkelson has requested that the subject documents be sent to the members of the Technical Panel and the Research Coordinators.
Dr. Torkelson emphasizes once again Dr. Stafford's out standing work on the international compilation of data on angiosarcoma cases. To date. Dr. Stafford's registry is con sidered by Panel members to be far more complete than the information published by the National Institute for Occupational Safety and Health.
000003^5
2- -
Unfortunately, Dr. Stafford has not received answers to the questions on page one of his tabulation. Dr. Torkelson requests that Dr. Stafford's tables be distributed immediately to the Vinyl Chloride Monomer Sponsors with a request that they cooperate in every way possible with Dr. Stafford and his international effort.
Sincerely,
JTS:ec Enclosures
IT. T. Seawell Project Manager Vinyl Chloride Research
.5
>
vvc 000003916
copied by MCA for distribution to the Vinyl ^.iloride Technical Panel and Research Coordinators, April 17, 1978, Mr. J. T. Seawell
IMPERIAL CHEMICAL INDUSTRIES LIMITED PLASTICS DIVISION : WELWYN GARDEN CITY
LIVER ANGIOSARCOMA CASES (REVIEW DATE - 13th MARCH 1978)
Pages 1
2-3
4 5-6 7-8
9 10 11 12
13
14-17 18
2 Significant ChangeB
^
US 23 - a few more details including information that case is at Great American Chemical Company
France 09 - ) France 10 - )
new cases
3 Help Still Required
Germany
- (a) Does anyone recognise NI0SH Case 08? If it is genuine may I have details please.
(b) Is Case 06 (initials NH) a Hoechst case and was it at Gendorf?
(c) What do I do with case 03? Did Dynamit Nobel fill aerosol cans? If not, which company is this and whore? Should I remove 03 froQ our
list?
Italy
-
What do I do with case 01?
USA
- (a) Is case 16 BFG? Louisville?Avon Lake?
(b) "
17 "
11
" Still Alira?
(e) Is case 18 Charlie Arthur?Avon Lake? Reconcile
two entries in table.
(d) Whose case is 20? Details please.
Also case 22.
(e) More detail required on US 25 please,
eg Company and Plant location.
(f) Re case 23 (Gt. American Chemical) NI0SH cays
he died 06-04-731 but SPI told ne 06-04-76.
Which is correct please?
VVC 0 0 0 0 0 3 9 1 7
w &
S 5 5*
S <7\ SC n
** *
~ "2
5 S>
g
5 fe ^ "2 3
ilui
%
OTHER CAREER HIGHLIGHTS
ITS
*O5 E
<n
wI^
5& 6
~ 13 h * e ^ 5 -a F
a p --* fa. --.
a& i J o 8 fe 5. C is * 2 * -t *- a. ^
bo*>H
JS
X
K
pi
9}
HISTOLOGICAL 1
; CONFIRKATION i
I C I PLASTICS D IV IS IO N BESSEMER ROAD WELWYN GARDEN C ITY
h
o
g
- M9
E-i U
3a
.+c>
t
<3 bO, Hg
e
e u a
o 3 tMa
Q *8 uw O3 "* a
C--
'C
IPS g g
1
o u
Sg
n
MS E- R
g
*3
iie*
FIRST TC DATE OF POSURN | DIAGNOSIS
1
*
YEARS OF EXPOSURE TO DIAGNOSIS
S OraN
r~-
<B
ON VO
so
LTN o oo mLPv & oo & o. g **
o
-
' VVC 000003918
ICI PLASTICS DIVISION BESSEMER ROAD
WELWYN GARDEN CITY
LIVER Angiosarcoma Cases - (Review Date:- Ijth March 1978)
AH dates use UK system DAT - MONTH - TEAR
Canada Sheet 1
Page 2
** All this information should be held confidential until it is published by Dr Theriault of Laval University in Quebec.
** Many of dates altered to fit NIOSH 31/3/77 list.
2 3456
78
% 10 11 12 13 14 15
IND t NO
NAME OR INITIALS
DATS OP BIRTH
COKPANT
FACTORY
FIRST VC DATE OF EXPOSURE DIAGNOSIS
AGE AT DIAGNOSIS
TEARS OF EXPOSURE TO DIAGNOSIS
TEARS OF EXPOSURE
DATE OF HISTOLOGICAL ESTIMATED DEATH CONFIRMATION EXPOSURE LE7EL
OCCUPATION onto?
CARED*
HIGHLIGHTS
16 OTHER COMMENTS
A SHAVT1 RIGA If
K
1 15-12-13
1944
1955
41
10
11 02-09-55 Tee
2 06-03-14
1943
1957
*3
14
14 21-12-57 Tee
3 26-08-19
4 05-04-19
5 | 07-05-11
f
6 15-12-19
< < 7O
09-11-19
o o o
-----!--- o0
S!
13-05-20
1 3-
1945
1962 1967
42 48
1944
1968
57
1947 1946
1971 1972
51 53
1961
1973
53
21 20 23-03-62 Tee 22 22 21-01-68 Tee
'a
24 05 25-07-68 Tee ------------- %
24 23 10-01-71 Tee
26 25 24-12-72 Tee
12 05 12-06-73 Tee
Reactor Cleaner
Operator polymeris ation
Smoker
Maintenance, Operator, millwright, pipefitter
Worked overtime Smoker
Operator, foreman
Worked overtime fton-raoker
Reactor Cleaner
Operator, foreman, satercoolifts unit
Worked overtime Smoker
Reactor Cleaner
Reactor Cleaner Reactor Cleaner
| Reactor j Cleaner
Water cooling unit
Worked overtime Smoker
Maintenance Worked overtime millwright Smoker
Machine Shop oper ator and poly unit
Worked overtime Smoker
Maintenance machine ebo]
In plant 25 yearsJ Smoker
tN
'I *9
f
oo & 0O3
IC I FUSTICS DIVISION
BESSEMER ROAD
WELWYN GARDEN CITY
CO
*5 VO o
0 1
i V\
og
BS 0 B
1
u &i ^
J SB -t O sc
11CM MO K
DATE OF DEATH
xt
o
h.
g
4V
Ck M M
11!
On 08
nn
*
c*88 88
NO UN
NO UN
AGE AT DIAGNOSIS
CD
O
h8 e- O u
B1
si
NO
& Id 8
u
1
**
o u
tn
FIRST VC :
EXPOSURE
J
*
OPA'*
O O o o rtr*s8
o o
!
8 >e* 5 to <N -s o o
O V
NO NO
8 o
LA o o d o
1
u **
Vi
K o
8
i
*
NAME OR DATE Or INITIALS BIRTH
CU
g
3u -
*
*4 V*
^-
.
1 i i 1 1 j
VVC 000003921
\
r
ICI PLASTICS DIVISION BESSEMER ROAD
WELWYN GARDEN CITY
LIVER Angiosarcoma Cas3 - (Review Date:- 13 March 197)
France Sheet 1
Page 5
2 3 4 56
7
8
9\
_____
10
11
12
13
14
15
16
j.ND C HO
!
HAKE OR INITIALS
DATE 0? BIRTH
COKPANY
FACTORY
FIRST TO EXPOSURE
DATE OF DIAGNOSIS
AGS AT DIAGNOSIS
YEARS OF EXPOSURE TO DIAGNOSIS
4
YEARS OF EXPOSURE
DATE OF DEATH
HISTOLOGICAL CONFIRMATION
ESTIMATED EXPOSUftS
L&vl
OCCUPATION
OTHER CAREER HIGHLIGHTS
OTHER COMMENTS
Cr j
15*04.24 RP
Rcrooeillt n00.01.46 18.02,67 43
A.
21
19 19.02.67 Tes
High
'olyvorker 19 years
Ref. Ravier et A1 Arch, Mai, Prof. 1 30 n 3 - ox 75
VI "
02 l
03.06.11 PCTJK Brignoud 06.07.59 15.01.75
63
16
12 24.01.75 Tee
High
Polyworker
10 ye&ra
p. 171-177
Ref. G. Bonneto*' et > "Mourelle press nedicale" 5 nor. 77 - p. 735
03
1
06.01,20 RP
St Fobs 00.00.46 15.01.75
55
29
29 29.06.75
195
High
Polyworker VCM Pro ?ef, Rety et A1
10 yeara duction 16 Ireb. Hal. Prof.
year* Co*- \ 37 n 6 Juin 76
pocoding 2 P. 551 - 555
years
04
27.01.27 PCUK Brlgnoud 19.10.4? 16.01.76
49
05 <
29.01.3e
'
< n
06 o
14.04.34
oo
i
owa o ___L
FCUK PCUK
l\>
Brigncud 18.01.65 13.05.76 Brlgnoud 01.03.58 12.08.76
38
42
26 26 04.01.76 Tea
11 11 13.05.76 Tes
16 13 11.09.76 Yea (MOSS (NIOSB say* 17) aaya 12X9.76;
High
High High
Production worker 8 yeara Autocleaner 18 years
Polyworker 11 yeara
Polyvorker 10 yeara
i
1
Kef P Coudere et A1 "Senaine dea bopltaux 10 Septesbra '76 Previously had bone ,aGgicsaroe&n
AOL prior to AS Ann.de Mai. Prof,
July *77. p 645 t 6
ICI PLASTICS DIVISION BESSEMER ROAD
WELWYN GARDEN CITY
LIVER Angiosarcoma Coses - (Rovieu Date:- 13 March 1578)
Franco Sheet 2
Pena 6
2 3 4 5 6 7 8 9 10 11 12 13 14 15
i AND \>CE HO
NAME OR INITIALS
OATS OF BIRTH
COl&AUT
FACTORY FIRST FC EXPOSURE
DATE OP DIAGNOSIS
AGE AT DIAGNOSIS
YEARS 0? EXPOSURE TO DIAGNOSIS
YEARS OP EXPOSURE
DATE OP HISTOLOGICAL ESTIi IATED DEATH COifflfiilATIOH EXPOSURE LEVEL
OCCUPATION
OTHER CAREER HIGHLIGHTS
16 other cc;:srrs
'
in
i 05 RX
00.00.27 RP
St Aubo.o
01.07.50 Aftor death mosa cay:
00.07.76
49 v
01,04.34 S0L7AY Tavaiuc 23.05.57 03.12.75
42
08.10,14 RP
St Fono 10,01.48 26.04,75 Tn.
62
26
19 23
10 7
'
,
24.05.15 RP
St Pons 00,12.56 00,01,73
53
j
< < n
o c c c> ci -------- l> > -----------1
n> N> U>
21
22 02.07.7*
Yoa
19 30.01.77
103
28 16.12.77 Tea
'a 21 00.01.73 7ob
\
High
Plnnt forccr.a
Died of oortlrcccia Senll lirer losioa fctiid after autopsy
High nigh
Packer ther polyvorkor
Pol~oricac 10 yearn In Operated 4,76.
tion
eulphtiria ronoval cf tua. .
Operator acid fac froa'liver end died
tory,store- aftor occccd surgical
keeper operation for bilia
general
hresshial fistula
aarrieoa
Rigb
Antocla7a Cleaner
Mao ia
Died ef FJl-C'cary
rachanieol cskolira 5 ^073
engineorir' after cureery
industry
_________ _________ l
ICI PLASTICS DIVISION BESSEJffiH ROAD
WELWYN GARDEN CITY
LIVER Angiosarcoma Cases - (Review Cate:- 13 fereh 1978)
Germany Sheet 1
Page ?
i 2
3 4 56
78
% 10 11 12 13 14 15
16
HD HANK OR DATE 07 COHFAHI FACTORY FIRST VC DATE OP AGE AT
: no INITIALS BIRTH
EXPOSURE DIAGNOSIS DIAGNOSIS
YEARS OF EXPOSURE
YEARS OF DATE OF HISTOLOGICAL ESTIMATED OCCUPATION EXPOSURE DEATH CONFIRMATION EXPOSURE
OTHER CARESS
TO DIAGNOSIS
LEVEL
highlights
OTHER COMMENTS
OT
i> 1 i QA
04.06 O0 Dynaait Voiodori 01.10.56 19.9.68 26.07.31 Dysaait 'roiadorf 14.10.57 25.9.70
16.07.30 Dynaait?
09.06.52 00.03.73
38
40 (39?)
43
12
12
25.01.6l
Yea
(NIOSH)
13
12
14.12,7
Yes
(HIOSH)
21
21
10.10.7:
Tee
(HIOSH
(HIOSH)
says 14)
Polyworker
VIs' Polyworker
Pi11jpg pesticide aerosol cam with VC
C 00000392
!
04.09.30 Vaeker
Burg- 16.04.57 bausen
.
r-pr01.01.32 Dynaait rolsdorf 16.12.62
26.11.74 00.00.75
EH
< <
09.05.36 Hoeohst
Gender?? 02.04.60
00.12.73 (NIOSH
says 30,00.74)
29.09. ?6 Waeker Burg- 15.04.54 12.11.75 hausen
j 1 1
44 43 33
49
17
17
25.11.7-
Yes
(NIOSH - ao
concent)
Polyworker & teap aatoeleaner
13 12 10.01.75 Yes
13 (NICSH says
14)
05 (NIOSH says 03)
16.12.74
Yes (NIOSH)
Polyworker
Polyworker (NIOSH says assistant factory chemist)
21 21 13.11.75 Tea (inosh
Autocleaner 12 yrs
says 12)
Forenan
Tech Dev
6 yrs ___________ i1
Dates altered to fit NIOSH 31/3/77 Ust and 1/78 "
Cates altered to fit
,Y/%n H3*
Reported under nonpolymerisation workers in mesa list of 31/3/77. Is this correct?
Reported under nonpolymerisation workers in NIOSH list of 31/3/77 A 1/78
ICI FUSTICS DIVISION BESSEMER ROAD
WELWYN GARDEN CITY
LlVOt Angiosarcoma Cases - (Review1 Zfet*:- t? March 1978}
Germany Sheet 2
Page 8
AIR) :e bo
2
NAME OR INITIALS
3
DATE OF BIRTH
4 COMPANY
5 FACTORY
6
FIRST VC EXPOSURE
7
DATE OF DIAGNOSIS
e
AGE AT DIAGNOSIS
9
Mr*
YEARS OF EXPOSURE TO DIAGNOSIS
10
YEARS OF EXPOSURE
11
DATE OF DEATH
12
HISTOLOGICAL CONFIRMATION
13
ESTIMATED EXPOSURE
LEVEL
14 OCCUPATION
15
OTKQl CAREEH HIGHLIGHTS
16 OTHER C0HHB1TS
T I)
? 19.10.1? 7
?
19.04.54
1975
53
y'*
RE
13.12.34 CWH
Karl
00.02.61 end *76
42
(HIOSH (HIOSH oay 1
oayo
16.6,76
2.12.59 bat CWH
hot CWH confirm
sonfira end 76)
30,02.61)
J
25.07.29 'danker 3urg-
10,10.55 28#cS,77
47
hauoen
FK
29.12.36 CWH
iarl
15.01,61 00.00.77
41
22
21 25.12.^
Tee
r
??
7
15 (NIOSH soya
17 but CWH confirm
15)
13 Still i NIOSH cayi alive
15 but CWH
' ft
eonfiru
13)
(NIOSH soys yee)
High peals
Autoworker A cleaner 8 yra
Next Job 3 yrs
Control rooa 1 jt
22
28o06.77
Yes
High
3 years
autoclave
cleaner
19 years
filter opera :or
16
10 07.03.77 Yes
High pe&ki 9 years
autocleaner
In NIOSH list of 16.2,77 awaiting details. These detail given by NIOSH on 31.3.77. Whose ease is this? Why ; v ve not heard 0/ i
Still Alive In job A was 1J% clean with ayerage 700 ppsi exposure and occasional 1000 +. In Job B, 1756 cleaner with average 250 pja. In Job C, 75 ppn average exposur
exposures identical to RE case froa !*- '
VVC 0 0 0 0 0 3 9 2 5
wry<!\v
cr
a
A
oa
& UA5
in 19 O uS
o
*nH
CO3 -qH a t
4> 4)
a r
0. pH
5a
> SW
B 93
3 'S
&ai . ri bfl n isgs
a s
IS
* o
*43H> r>Hd uO+> 01
8 E 8C R
s< <D -ct aO ,1--*
s
*
Q
o ato uS
3
ro !> CM
i
a q8
WC 000003926
ICI PLASTICS DIVISION BESSEMER ROAD
WELtfYN GARDEN CITY
LIVER Angios&rcoaa Cases - (Review Data:- 13 March 197B)
i-c/io 10
Could Japanese P7C Association bo asked to eonaent on ibis table.
2 3 4 5 6 7 8 9 10 11 12 13 14 15
f AND CE NO
HAKE OR INITIALS
MTS OP BIRTH
COMPART
FACTORY
FIRST VC EXPOSURE
DATE OF DIAGNOSIS
AGE AT DIAGNOSIS
vSrs op
ECPOSURB TO DIAGNOSIS
YEARS OF EXPOSURE
DATE OP HISTOLOGICAL DEATH CONFIRMATION
ESTIMATED EXPOSURE
LEVEL
OCCUPATION
onus CAREER HIGHLIGHTS
16 other corecrrs
T0K0JI MORI
MITSUI TOATSU 01-09-22
NAGOYA
1951? /niosh '
|bc-o<_53j
4.
52
22
^ : i fN
SHizno SATO
SHIGEO TAHAEA
SUB CON NAGOYA TRACTOR
TO Mirsu TOATSU
rh
MITSUI TOATSU
KAGOIA 1953
Hot >68
43
KAZOTOSHI CKO
MITSUI TOATSU
NAGOYA
Dec *67
02,08.39
00,11,58 10,08,76
47 37
16 18
!3 yrs auto-
22 24-10-75 YES
often
slave cleenc r
3000 ppa )964 - assign >d
/ hiosh \ and no pro - to differs it
| Ho comaeny tective fork flince b Ld treasures 111 health.
until 1974
Reactor cleaner 1964-1974
H-PJ-69
Dec *67 1&- 10,08.76
Japan Tines 25-10-75
Pro-ccneerous di ier 3f liver. Japan rises ?5.10.!?5
Japan Tinea 27-10-75 (aose figures uncertain - bad prist) Japan Tines 27-10-75
<rj <3
3 O
oo
rs
i
L_
1
IC I PLASTICS D iv is io n
BESSEMER ROAD
WELWYN GARDEN CITY
l
S5
13
u-
<HXru-Ht
-[O?I Og
^0) o(h
UR0 ij vJ
5
R t.
?
W IPihf.
Cm
ot'
E
A* ha> (f4j
g-
? ft
g * 3 g'js "
e
Half!!
a " ft [! 3 ft l' 5
E3
iP
d
-8JL
"(6 CM ft ON
t JC\ jhlJ5.i< udI Ofnl
H c--\ <o Vtr tl Cn'-.
s
ar 8I o 6t/->* &*4
O ES
Cd & 5u
tv
fj
fS M ato 0 [=5 tl ON S8
|0
JL
X` L- O
cTu\ _TT
IC I PUSTICS DIVISION
* R o
Ml M
8
ft
&
3
'S <*N
VVC OOOO03929
IC I PLASTICS DIVISION
M \o
U
iJ
ir\
Ir
||l <*>
a! is
8S
i g
9
*a as <o SB
cn
ii
W2 8
Sg -
Ss
o &s
a ft. eg || | tr
a
6* M
aj * S MU O^ 's
*a QW
MS
3 a
Eg >o
tr> g s
i
g
&e
si
| C4 Is
i .. e
o
e 3 rJ <T H*P
|U0"'
1c JlSSf *2*1
-- r- > o ar o.
a
is
a9 s a < *>
i
._ K ,4 \sar!
a.s>
.
04 04
f0i)) <
?
CN
UJ cn
8 cB
M
6 ! Z k ? -
a* nO A -3 -a Vft J<33 a a *o a -H ^
K3nS.e
3usAfi.i.v
!BIS "|8
n 4* o go 88 "8 oB E o* H *9 H tx Da
-
s o\ o
|
?:
04 c _ u C4 4j
%a3
nk< c OU
c^ S' M 3 r. 04
&% c> Q. 04
*r o4 s
p4 a
M a
5
3 S.
-5 U
03
?: *4
*
8
58 S'
8
I
m <*. f~\ 8 04 O
,,4C 000003930
-- -----------------------------------------
^
ICI PLASTICS DIVISION FffggEMEft road
WELWYN GARDEN CITT
LIVER Angiosarcoma Cases - (Review [kite:- 13 March 1978)
USA SHEET f
* eyatem of dates ' M0HTH " T1*
2 3 4 5 6 7 8 $ 10 11 12 13 14 15
AND E NO
NAME OR INITIALS
DATS OP COMPANY BIRTH
FACTORY
FIRST VC DATE OP EXPOSURE DIAGNOSIS
AGE AT DIAGNOSIS
TEARS OP HLPOSURB
TO DIAGNOSIS
YEARS OP DATE OP HISTOLOGICAL ESTIMATED EXPOSURE DEATH COHFXRHATIOH EXPOSURE
LEVEL
cccupatiou
OTHER CAREER HISHLXBHTS
Pare 14
16 OTHER COMMBTFS
EARL PARK 17-10.23 BFG
louisvil 09-12-4* 03-03-73
49
19-08-33 BFQ
Louisvil 15.11.5; 00-05-70
37
25.05.15 BFG
15-01-24 BFG
25-01-12 BIG
RAY AUSTH 23J1.20 JONES?
BFG
Louisvil e 28.11.45 19-12-73 touisvil e 06-07-55 19-08-67 LonlsvlL a 19-06-44 09-04-64 LouisvlL e 17-01-65 00-02-74
58 A3 52 45
nmifljs j 03-05-22
SMART
ucc
S Charle- 27.08.44 00-00-68 ston
*5
< O
O O O O O i v>>
______ L
06-05-20 Goodyear Niagara 07-10-46 00-08-61
41
24
21 >3-03-73
YES
14
13 27-09-71
YES
(tflOSH e iy
28.09.71 )
28
28 19-12-73
YES
15
15 >7-01-68
YES
20
20 09-O4-&4
YES
12
12 >4-07-75
YES
24
>3-03-68
YES
*4
J*
15
15 >9-08-61
YES
US Air Force
Rolling Stone Art Ref 1 BY Acad of Sc Syz; Ref 1 Also Block JAM* V7/74 p53 Ref 1 ' Ref 1 Ref 1 Ref 1 + Louisville Tine 23/7/75 Retired April 1974 Ref 1
Ref 1
IT
B aI
IC I PUSTICS DIVISION
\o O u
III
1
III
-J n gg
M i13 11
n 3 CC<TO-\ S3
gfe -
eg
su
1 o &1
sg|
Os
I li|
a to 5 8
ta 3
SI
t".
3*a. co s|
S| NO Sj m
i m
s
r 1
n bH a
ii N
-- ..s 3
I.
.
S* ph o to
y|i + 8b &-
*> T"
*3 +s r-1!vn"
1 EJ
f
Ref 1
Charleston D ally H ail 21/7/75
a &S- +*
8B
S* **
is sH .
<14-4 jVQkoeS. *O
*4 3o iA
8
4V*
,, sO
010
cn
n
at
*
o 41
rE<9i-i *6MO>-
-9 u
a
& 5
fUpc.
SQo 2CB
J3 a
O-i n^?>1
B|
J 8B
if
5Ma>
OUNl i-O4 -4H*
-- &
8 a
t 0aBB Rr\f-\ CO ON X A XA ? 232
NOSn' I
s CCMN cs
On o
S K1 ac- N ON
On
On
Co ar'l
*r
IIAA
CN US
NT
5? 1
%2
o
CO
1
oC-
<A?
S
ON
a 2
o
A 2
o
S
un o
a*
IN
ot 3
J 2
V TwTMo
o
5 | +Kno
Ho> f+ J3
I A4 2 W >
tr*t
|f
<4u03
I1
C5 B
b
?
cN
OoS
A
CO
7 CM
5r> -
? c<*N**
7
Os O
s 3
o
CN 1 r
5 2i
--uv -...... UN cs
X
? 8
i^s
So^
M
Ilf
VVC 000 003932
_ ...... _
_L
I
\o V& <1
* 33
<0
9
IC I PLASTICS DIVISION
BESSDffiB ROAD WELWYN GARDEN CITY
upoATieirs
ICI PLASTICS DIVISION BESSEMER ROAD
WELWYN GARDEN CITY
USA Shot 4
LIVER Angiosarcoma Cases - (Review Ekto13 Max-oh 1978)
r> - --
j
2
34 56
>4
--------------- *-----------
7 0 9 10 11 12 13 14 15
AND HAKE OR DATE OP COMPANY PACTORY FIRST VC DATE OP AGE AT
E NO INITIALS BIRTH
EXPOSURE DIAGNOSIS DIAGNOSIS
YEARS OP EXPOSURE
DIAGNOSIS
YEARS OP EXPOSURE
DATE OF DEATH
HISTOLOGICAL ESTIMATED CONFIRMATION EXPOSURE
LEVEL
OCCUPATION
OTHER CAREER HIGHLXGEFrs
Pg 12
16 OTHEB COMMQfTS
22?
Bra Leuieril. e lo 10
24-01-76
Charles
Edward
Ncore
17.05.17 ucc
Sooth
1939
Chariest IQ
27.05.77
60
i
<
n
f0
0 0 0 w >0
UJ
1
07.08.10 7
7 00.02.47 10.03.77
67
28 ALIVE
t1
Louisville Tines 26-1-76. Said to be 10th AS Tictln at Bel Lone factory of a have dfcd so far.
38
24?
27.05.77
Tee
Medina to 1941-65
1937-39 N M Wheeler letter of
(NIOSH
High for Neo-solveut mta off 18/0/77 to J Stafford
aays 26)
24 years vinyl resin and on
glvea details.
unit nwti
labourer
Dispersion vinyl resin unit first as fitter helper, tbei shift utility can
1939-*1 cay have been exposed as reactor cleaner 1943 bocan
shift fitt T
1946 beeaa t
shift'eiil ity
aaa 26.4.1965 ployaent was teraina ted
30
20
10.03.77
Yea
1
so
o cj
CD
IC I PLASTICS DIVISION
ll| IA
I
IS "
NS
"
l
ci
I
ill CA
+a a 1 eg cs rj @ fw Er3>j a ?>
- obp| au
O a SB
Q O
ao
t>* >-*
eO'-* K
t*i oo oCO CN
o CO
CM
Ma
o\ to CO Ctf3
Js
^Q o L-
[3
o
r-< to c P,
l|
1
t, 53 t- Ss
33 o
b|
\Q is
a
u>
8 u
ta 1
o o
G ry fd C3
a^
sieg
oCM CM
<J\
U\ v 1 !
^ iI ^ ji 5 jo j 81 2 |
ca LA
R
oo oo'
oo oo
4* 3.
<r*--<-
CO we
r?|?n%
^ r.
% OcT
lA
O
lA
iS S
^
JS
*-
. __
.
* *>
'
VVC 000003935
1
! ( ) I
/
Copied by MCA for distribution to the Vinyl Chloride technical
Panel and Research Coordinators, April 17, 1978, Mr. J. T.
Seawell
J Stafford Division Manager Health & Environment Protection Welwyn
See Circulation List Attached
ICI Plaeflc* Division
Bessemer Road Welwyn Garden City Herts AL7 1HD
Telephone Welwyn Garden 23400 (STD 07073) STD code from London area - 96
Tele* 264251
Copies to
Your ref
Our ref
JS/ERA DS0-10?
Tel exl
3162
Date
16 March 1978
ASL CASES
With ay IJth March 1978 review of the ASL cases, may Z plead for help, I hare been revising these tables at regular intervals but aa handicapped by lack of response on sons of the questions I raise* Will you please check through your company and country cases and let ne have notes of misinformation and also fill
me in on the blank spaces*
So far as I can see the ASL cases in the VCK/PVC industry are distributed:
USA
- 23
Canada
- 10
Germany
- 10
*
France
- 10
Sweden
-4
Italy
-2
UK - 2
Japan
-2
Yugoslavia
-2
Czechoslovakia - 2
Norway
-1
Belgium
-1
69
lIjj
J Stafford
VVC 000003936
Liver Angioeareona Cases
Circulation:
Dr Q Paddle Dr D P Duffield Dr W G F Adams Dr D Winter Hr G J Sleddon/Mr A W Banes Dr D W Fleeter Mr W Adams - Vinatex Mr P Sharrock - BP Mr R Hards - BIP DrBtf Duck - BP Mr T L Phillips - BP Mr B H P Hutehesson - CIA Mr A S Ganett - CEFIC
Mr H Vallender - CIA Dr W Freiealeben - Wacker Dr L de Boer - Shell Mr J C Thomas - Rhone-Poulenc Dr T Garlanda - Montedison Mr M Bonnefoy - Solvay Dr B List - Lonza Mr P G Claus - APME Dr J Kammuller - Shell M* C Sjoelin - Kemanord Mr C Rongneg - Norsk Hydro Dp R Praefke - CUH
Mr H Ebainger - VKH Mr P de Voogd - Shell
Dr Lloyd-Jonee - BP Dr G Riley - Hillhouse Assistant
Works Manager Dr F W Beat - Millbank
Dr G Norcross - Everberg Mr C d'Haenens - APME
-
Dr T R Torkeleon - Dew
Mr J Lavrence - SPI Hr N Wheeler -- DCC Dr A Rosa Adams - Air Products Dr Walter D Harris - Uniroyal Inc.
Dr D Douglas - HiAS Dr P Baxter - UHAS
Dr J Stafford (6)
JS/ERA/DSO-107 13 March 1978