Document vB6LRK06jzvm0y2JYwKBJd3Bb

eet Nr* 0. P. Bigtlow April 5# 1957 Nr. X. Davis National Adhaalvaa Company 1700 Vast Front Straat Plalnflald# law Jarasy Rai Polyvinyl tthara SSBN and BBC Daar Hr. Davlai Nr. 0. P. Bigtlov of our Bakallta Company baa raquaatad that a writa you oncoming tha toxlolty of tba subjaot natarlals. Tbaaa ara both polynarlsad vinyl athara and ara tha aaaa axospt far dlffarant vlaeoaltlaa. ifcssa aatarlala ara vary lnart physiologically* and our work on than haa haan limitad. Xa rapaatad doaaa of polyvinyl athar ta rata, our laboratorlaa found that 10 par cant In tha dlat (10.4 grama par kilogram body walght par day) had no advaraa affacta on tha animals. To avaluata tha irritating propartlas, a NO par aant solution In athyl athar was appllad to rabbits* akin# and only a trass of irritation to tha akin rssultod. A 10 par aant solution In daodorlssd karooana aauaad no ays Injury whan Instillad In rabbits* ayas. Va trust that this information will ha hslpful ta you. Xf wa nay ha of furthar aarvloa# plaaaa lot us know. Tory truly yours# . MEDICAL DIRECTOR ucc 063329