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kTPE OF test ROUTE OF EXPOSURE
: LC50 - Lethal concentration, 50 percent' ki'll
: Inhalation
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SPECIES OBSERVED r'^cE/DURATI0N
: Rodent - rat . 18 pph/15M
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C EFFECTS :
ahayioral - tremors
behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration . - respiratory depression
REFERENCE :
Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants.,
RG 21 2XS, UK) V.l-
1981- Volume (issue) /page/year-: 1,239,82
TYPE OF TEST ROUTE OF EXPOSURE
: LCLo - Lowest published lethal concentration : Inhalation
SPECIES -OBSERVED
: Rodent - mouse
DOSE/DURATIQN
: 20 pph/30M
TOXIC EFFECTS : Behavioral - general anesthetic
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REFERENCE :
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American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges
Pkwy., Akron, OH 44311) V.19-
1958- Volume{issue)/page/year: 21,394,60
TYPE OF TEST
: LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE
: Inhalation
SPECIES OBSERVED
: Rodent - guinea pig
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DOSE/DURATION
: 30 pph/3 0M
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TOXIC'EFFECTS :
Behavioral - general anesthetic
REFERENCE :
American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges
Pkwv.. Akron, OH 44311) V.19-
1958- Volume(issue)/page/year: 21,394,60
r- 3 OF TEST
LCLo - Lowest published lethal concentration
iwJTE OF EXPOSURE
Inhalation
SPECIES OBSERVED
Mammal - species unspecified
DOSE/DURATION
200 ppm/18M
TOXIC EFFECTS :
Details of toxic effects not reported'other than lethal dose value
REFERENCE :
International Polymer Science and Technology. (Rapra "Technology Ltd.,
Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year:
3,93,76
OTHER MULTIPLE DOSE TOXICITY DATA
TYPE OF TEST
: TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE
: Oral
SPECIES OBSERVED
: Rodent - rat
DOSE/DURATION
: 23400 mg/kg/13W-I
TOXIC EFFECTS :
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Liver - changes in liver weight
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Blood - other changes
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Biochemical - Enzymeinhibition, induction, or change in blood or tissue^
levels - transaminases
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REFERENCE :
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BFG39194