Document v6b8QbyYaqgxz2D678LYg8OwR

MEMORANDUM OE MEETING March 11, 1976 BETWEEN : Industry Representatives of CTFA Committee on Asbestos in Talc . . - Norman Estrin, CTFA ' George Sandland, Bristol-Myers Robert Rolle, Johnson and Johnson George Lee, Johnson and Johnson * , John Schelz, Johnson and Johnson and * ' Representatives of the Division of Cosmetics Technology Ronald L. Yates, Product Composition Branch ` Henry M. Davis, Product Composition Branch SUBJECT: Meeting with CTFA Talc Committee for the Purpose of Discussing ' the Results of the Testing of Talcum Powder Products Using a CTFA Proposed Method for the Detection of Asbestiferm Amphibole Minerals in Cosmetic Grade Talc. Dr. Estrin requested this meeting for the purpose of discussing the results obtained from the analysis of 15 coded, samples of cosmetic talcs that had been sent to CTFA by the Division of Cosmetics Technology on November 4, 1975. The samples were previously analyzed by Dr. S. Z. Lewin using x-ray diffractometry. DCST also analyzed the same samples using optical microscopy techniques. These samples were requested by the CTFA to evaluate methodo logy that they are proposing for the detection and determination of amphibole minerals in cosmetic talcs. At commencement of meeting, Dr. Estrin provided all present with copis of the results obtained from the analysis of the samples provided by DCST. Mr. Davis gave each participant a table identifying the coded talcs. Mr. Davis and Mr. Yates were also provided copies of the proposed analytical method for the detection and determination of amphibole minerals. The method consists, briefly, of a combination of two techniques; x-ray diffractometry and optical microscopy. A compressed pellet of talc is slow-scanned in the x-ray diffractometer under previously determined conditions. If amphibole is present, quantity is estimated by comparing net count to count obtained from talc standards containing known amounts.of amphibole (tremolite). The sample is then examined by optical microscopy using dispersion staining techniques. This step is used to confirm amphibole and to determine whether the mineral is present in the fibrous form by OSHA definition. HHS00000065 Meeting 2 The results of the CTFA analyses by x-ray dif-fractometry were, with the exception of one sample, in general agreement with those obtained by Dr. S. Z. Lewin. However, the results of the optical microscopic examinations of these samples by CTFA and DCST could not be compared due to the usage of differing definitions as to what constitutes a fiber; i.e. length to diameter ratios of 5 to 1 and 3 to 1 respectively. m- _ Dr. Estrin stated that these products which were analyzed by Dr. Lewin and the CTFA committee were* obtained by Dr. Lewin prior to 1973 and are no longer representative-;' of commercially available cosmetic talc products. Attachments: CTFA Talc Committee - ' 1* Analysis of FDA Samples for Asbestiform 'Amphibole . 2. Detection of Asbestiform Amphibole Minerals in Cosmetic Grade Talc - Division of Cosmetics Technology .v 1- Identification of Cosmetic Talcs Tested for Amphibole Minerals by CTFA Talc Committee HHS00000066