Document v6MeVRLna9rDJRG38NYb54k5m

OECD polymer of low concern (PLC) criteria OECD = Organisation for Economic Co-operation and Development Polymer Fluoropolymer PTFE TFM-PTFE PFA FEP ETFE Polymer composition MW, Mn, MWD Alternative Materials PE PP PS PA 66 PMMA PPS PEEK Silicate glass Stainless steel Ceramic Symbols all fulfilled not applicable partially acceptable not really acceptable Legend Polymer composition Polymer composition, structure & elemental composition; including CAS no. MW, MNnu,mMbWerDaverage molecular weight and oligomer content are used criteria for PLC assessment. MWD --> polydispers Wt-% oligomer Weight % of oligomers < 1000 Da ElectricEall. cChha.rogreionic character can be: anionic, cationic, amphoteric, nonionic; cationic polymers associated with aquatic Reactive functional groups Ato(RmFGor) associated group of atoms in a chemical structure that is intended or can be reasonable expected to undeergo facile Functional group equivalent weight (FGEW) FGEW is defined as the ratio of Mn to the number of functional groups in the polymer Low MW leachables Are chemical molecules, either inorganic or organic, that migrate (i.e. leach) out of the polymer Water/lipid solubility,octanol water partition Water solubility = extent to which a compound will dissolve in water; negligible water solubility < 1x10E-6 mg/L = ParticlPeasrthicalet asirzeesmall enough to reach the deep lung upon inhalation are associated with adverse health effects. Polymer parti nce to physicPaoll,ycmhemr sitcaabl,ilbitiyological transformation. Breaking down into smaller particles is ccritical. Molecules with Mn<1000 Da are c ThermTaol bsteaabsilsiteyssed when used as intended or in extreme temperature during dosposal. Theermal stability testing may in Abiotic stability Polymers are stable, monomers are not. Abiotic degradaton may involve sunlight, water or oxygen. BiotIisc astsasebsilsiteyd by whether the polyymer is degraded by microorganisms under oxygenated (aerobic) or anoxic ( anaerobic Wt-% oligomer Electrical charge (=insulating) Reactive functional groups (RFG) Functional group equivalent weight (FGEW) ; including CAS no. assessment. MWD --> polydispersity index polymers associated with aquatic toxxicity nable expected to undeergo facile chemical reaction l groups in the polymer e. leach) out of the polymer water solubility < 1x10E-6 mg/L = 1 ppt erse health effects. Polymer particles should be > 5 m Molecules with Mn<1000 Da are capable of crossing cell membranes Theermal stability testing may involve TGA lve sunlight, water or oxygen. ed (aerobic) or anoxic ( anaerobic) conditions Low MW leachables Water/lipid solubility,octanol water partition Particle size Polymer stability Thermal stability Abiotic stability Biotic stability