Document v1mBK1oRygbNGGQ4OQpKe2J9q

2U minutes LAPEES AVAILABI 10,. USE ON AIHA PP QGi\AM APFIL 1 9 V KEfigE- ING LABOFAb~(T~l OF APPLIED PH2I0L0G- 1. Experimental Observations on the Ingestion of Aluminum by a Normal Human Subject, by ..obert A. K e h o e , et a l . A study of the alimentary absorption of certain aluminum compounds administered daily to an experimental subject ever come period of time at different levels of dosage. Balance experiment with daily observations on intake by mouth in food and ou.put in feces and urine, accompanied bj blood level determinations and clinical obsic r-va ..done . Lemons a a t _oa of the negligible alimentary absorption A few additional observations obtained under other conditions demonstrate the absorbability of respired aluminum. 2. Fur chez- Observations on the Ingestion of Lead by Normal Human Subjects1. 'Ihe Daily Ciel Louage Compatible with a Balanced Lead Metabolism, by ..obi t A. E e h o e , et al. Continuation of the observations previously desezibed culminating in the demonstration of the approximate level of daily lead ingestion (and absorption; that z'esults in no progressive lead accumulation in .he body. J. The Urinary Pluorine Excretion of Men Employed in Alkylation Plants Using the Hydzo&en Fluoride Process, by Edward J. Larg e n " . (Could possibly be co'ftrdiziated with description of exposure (processes' involved) in such plants and discussion of actual hszaz*d by representative of Universal Oil Products Company if desi r e d . , Actual data from a number of plazzcs; some observations repeated on several occasions, with comments on significance. A. The Metabolism of Fluorine in the Human Subject. The Excretion of retained Fluorine, by Edvard J. Largent Continuation of systematic studies on the behavior of 2u minutes 15 minutes 2i> minutes fluorine in the human body, these having to do vith the rate of loss of fluorine from the body following absorption sufficient to result in retention of fluorine in the tissue. 0 Minutes Any one of these vould require from 2u to 2u minutes to present. 5 . The Paysiological Effects of the Absorption of Xylidine Upon Experimental Animals, by Joseph P . Treon A systematic toxicological investigation of this compound. The results could be compared vith those of monomethyl aniline and the general effects of acsorption of this series of compounds could be commented upon, using illustrative data. Neal and his associates at Bethesda, Maryland, have done a great deal of work on Xylidine and if desirable an effort could be made to have a joint presentation of the high spots of both investigations. If this were done, perhaps minutes for both vould suffice, one taking a little more than the other to present the general considerations. 6 . Other compounds investigated by Dr. Treon and his asso ciates are ready for reporting in a manner similar to that indicated above, are; (a; aminodiazine and methylaminopyrimidine; (b; methyl acrylate and ethyl acrylate; (c; hexachlorobutadiene, hexachloropropyleae and pentachloropropylene. 7 . Further toxicological vork on several compounds could be presented by one or another of the staff members vho have been engaged in the vork. ; (aj 2-aminothlazole* (bj orihonitrodiphenyl and related compounds (plasticizers;* (c; tetraethyl tin* (dj trimethyl phosphate. aj >j minutes bj 20 minutes c ) l'J minutes d) 15 minutes In some instances ve may require releases from secrecy orders In order to be able to deal with the subject matter of these investigations. Therefore those in this group as veil as certain of those in group 6 must be regarded as tentative and, therefore, are not to be given any publicity at this time beyond the program committee. We shall be able to act promptly, hovever, if a specific paper happens to fit veil into your program. 13 minutes o. Uev Analytical Methods as developed by J. Cholak, Waldo Younker and Donald H u b b a r d . (aj The Determination of DDT In Air - (YounkerJ A method suitable for analysis of air for DDT content in industrial plants or other establishments, or in connection vith experimental vork with animals. (bj The Determination of Antimony in Biological Material Uiubbard) . A precise method for dealing vith small quantities of antimony in tissues, blood and excreta. D . Our vork on the Toxicology of DDT could be assembled and suitable portions of it prepared for the purposes of this meeting if d e s i r e d . . If this vere done, certain aspects of the problem might veil be dealt vith by Neal and his associates and by the other groups that have been engaged in this vork for some time. I hardly think this the most suitable meeting for presentation of this subject, but am willing to defer to the visiles of the Committee.