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WVU :: School of Medicine:: Community Medicine :: C8
C8 Health Project Results C8 & Other PFC Levels
The tables and graphs on this page (links below) are summary results for the plasma concentrations of C8 and C8 Sulfonate of the participants in the C8 Health Project. These results include participants from whom a sufficient and viable plasma sample was obtained. Plasma concentrations are presented for the overall population, as well as stratified by common demographic characteristics. Demographic data used for age, gender, education and income were those provided by the participants during the completion of the survey. The accuracy of the demographic summaries reflects the accuracy of the responses provided by the participants.
The qualifying water district is the water district for which the participant presented the requisite qualifying documents to be eligible to participate in the C8 Health Project. This "qualifying" water district mayor may not reflect the water district or source of exposure to C8 or other PFCs. This concept is important to understand, because "peer review" efforts may take more elaborate approaches and show slightly different geographic distributions.
Results for all participants with detectable levels of C8 and C8 Sulfonate are included in the summary tables and charts on this page. Subsequent reports may use different inclusion/exclusion criteria, population substrata, etc. Small differences can result from such particular analytic decisions. The summary results reported here, then, represent a synopsis that adds to existing knowledge, and which may be further refined by far more detailed work that will be submitted to peer-review journals.
Few, if any, previous human studies ofPFCs of this magnitude have been conducted. And, while this is clearly a unique population, little is known about what level is considered to be "acceptable" or "dangerous." Seeking the answer to such questions is, in part, the purpose of the C8 Health Project and the mission ofthe Science Panel.
All graphs and tables were prepared by the WVU School of Medicine and are copyrighted.
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Cs & C8 SulfonateJ)l,\.~ma ConcentratiQll~-"J~)QJ2\!.lation Summary (58 KB)
C8 & C8 Sulfonate Plasma Concentrations Stratified by Age & Gender (44 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Oualifying Water District (41 KB) C8 &_C8 Sl!tfum~te.H"sma Concentr"tiQnsStratified by.E.Q!Js<!'\tiQll (39 KB) C8 & C8 Sulfonate Plasma Concentrations Stratified by Income (45 KB)
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41712008
Population Results for C8 and C8 Sulfonate Plasma Concentrations
All Age and Gender Groups
Mean
Std. Error of Mean Median Mode Std. Deviation Variance Minimum Maximum Percentiles 25
50 75
Statistics
C8
C8 Sulfonate
82.9848 .93136
28.2000 9.60
240.82333 57995.875
.50 22412.00
13.4000
23.3571 .06010
20.2000 16.60
15.50915 240.534 .50 759.20 13.9000
28.2000 70.6000
20.2000 29.0000
Population Distribution of C8 Concentration
250
200
'00
50
a
.50
100.50
202.40
315.40
467,60
C8 Concentration (ng/mll
759.50
2008 West Virginia University School of Medicine
400
300
c~
."tJ" 200
...~
100
o
Population Distribution of C8 Sulfonate C8 Sulfonate (nglml)
Median Values for C8 and C8 Sulfonate Based on Quarter of Participation
III C8 (ng/ml)
50.00
11II C8 Sulfonate (ng/ml)
40.00
c 30.00
..'5 ..::;:
20.00
10.00
0.00
3 Q 2005
4 Q 2005
1 Q 2006
2 Q 2006
3 Q 2006
Quarter & Year of Participation
2008 West Virginia University School of Medicine
Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Age
& Gender Groups
Age Category <10 Years 10-19.9 Years 20-29.9 Years 30-39.9 Years 40-49.9 Years 50-59.9 Years 60-69.9 Years
Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation SId. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean
C8 80.7732 34.0000 .70 2070.60
131.97626 2.35785 63.0104 27.2000 .60 1236.60
99.93089 1.04321 45.8281 21.2000 .60 1102.60
79.42039 .79401
68.6560 22.4000
.50 8162.80 212.95424 2.08498 90.6931 27.8000
.50 17556.60 299.87368 2.74675 108.1281 33.5000
.50 8416.50 303.90537 2.95416 114.8070 42.7000
.60 22412.00 355.41953 4.25263
C8 Sulfonate 23.0641 20.0000 1.10 202.10
13.48214 .24098
22.4855 19.9000
.60 198.80 12.12196 .12668 19.9271 17.9000
.50 199.80 11.50305 .11528 20.4713 18.3000
.60 236.30 12.02323 .11799 21.9906 19.1000
.50 564.30 14.72075 .13511 25.2993 21.9000
.50 291.50 16.23525 .15804 28.9309 24.9000
.50 291.50 18.65860 .22380
2008 West Virginia University School of Medicine
Age Category 70-79.9 Years
80+ Years
Total
Mean Median Minimum
Maximum
Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean
C8 113.5256
39.5000 .70
4751.50 227.82005
3.83175 104.2679
39.3000 .70
2299.10 197.64315
5.98095 82.9848 28.2000
.50 22412.00 240.82333
.93136
C8 Sulfonate 30.0827 25.6000 .50 759.20
25.27402 .42618
29.1912 24.6000
1.50 275.50 23.20182 .70406 23.3571 20.2000
.50 759.20 15.50915 .06010
50.00
40.00
~.,5.. 30.00
~
c
~
'5 ::~!: 20.00
Median C8 Concentrations for Age & Gender Groups
"Gende~
.Female IIiIIMaie
10.00
0.00 <10 10-19.920-29.9 30-39.9 40~49.9 50-59.9 60-69.9 70-79.9 60+
Years Years Years Years Years Years Years Years Years
Age Category
2008 West Virginia University School of Medicine
Median C8 Sulfonate Concentrations for Age & Gender Groups
30.00
~Gender"
.Female I!IlIMaie
~.s 20.00
~
,Cg
"(/)
~
Ii
~ 10.00 :;;
0.00 <10 10.19.920_29.930_39.940_49.950_59.960_69.9 7D-79.9 8D+ Years Years Years Years Years Years Years Years Years
Age Calegory
2008 West Virginia University School of Medicine
Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Participant's Qualifying Water District
All Age and Gender Groups
Qualifying Water District Mason County, WV
City of Belpre, OH
Little Hocking Water Association, OH
Lubeck Public Service District, WV
Tuppers Plains, OH
Village of Pomeroy, OH
Total
Case Summaries
C8 (Final Test C8S (Final Test Value; Numeric) Value; Numeric)
Mean
14.5561
22.9114
Median
12.0000
19.7000
Minimum
.60
.50
Maximum
525.20
274.90
Std. Deviation
11.58330
14.59610
Std. Error of Mean
.10490
.13251
Mean
43.3626
23.2543
Median
27.1000
20.4000
Minimum
.50
.70
Maximum
7932.00
245.80
Std. Deviation
107.52400
14.99425
Std. Error of Mean
1.16957
.16340
Mean
226.7114
23.4114
Median
132.4500
20.3000
Minimum
.60
.50
Maximum
22412.00
759.20
Std. Deviation
349.68251
15.68320
Std. Error of Mean
3.11943
.14016
Mean
94.3865
25.3850
Median
45.9000
22.1000
Minimum
.50
.50
Maximum
17556.60
291.50
Std. Deviation
325.29059
15.87031
Std. Error of Mean Mean
2.54172 39.5996
.12433 21.9942
Median
28.1000
18.9000
Minimum
.50
.60
Maximum
8162.80
585.20
Std. Deviation
86.44557
15.92322
Std. Error of Mean
.74184
.13679
Mean
14.0692
20.6339
Median
11.5500
17.7000
Minimum
.60
.60
Maximum
287.00
207.40
Std. Deviation
13.21007
13.92657
Std. Error of Mean
.22209
.23437
Mean
82.8443
23.3475
Median
28.2000
20.2000
Minimum
.50
.50
Maximum
22412.00
759.20
Std. Deviation
240.09476
15.46953
Std. Error of Mean
.92960
.06001
2008 West Virginia University School of Medicine
Median C8 Values for Qualifying Water Districts
125.00
100.00
~S .,() 75.00
I:
..'ij ..::;:
50.00
25.00
0.00
Mason County, City of Belpre, Little Hocking Lubeck Public Tuppers Plains, Village of
\NIl
OH
Water Service Dislrict,
OH
Pomeroy,OH
Association, OH
V'N
Qualifying Water District
Median C8 Sulfonate Values for Qualifying Water Districts
25.00
_20.00
s~
~ 15.00
:o;f
VI
l3c 10.00
..'C
..::;:
5.00
wv 0.00
Mason County, City of Belpre, Little Hocking Lubeck Public Tuppers Plains, Village of
WJ
OH
water Service District.
OH
Pomeroy.OH
Association, OH
Qualifying Water District
2008 West Virginia University School of Medicine
Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Years of Education
All Age & Gender Groups
Case Summaries
"Years of School Completed"
No Response
Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
<12 Years
Mean
Median Minimum
Maximum
Std. Deviation
Std. Error of Mean
HS Diploma or GED
Mean
Median Minimum
Maximum
Std. Deviation
Std. Error of Mean
Some College
Mean
Median Minimum
Maximum
Std. Deviation
Std. Error of Mean
Bachelors Degree or Higher Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
Total
Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
C8 74.6807 27.3000 .90 1976.90
147.11520 4.37448 71.1974 27.9000 .60 2523.80
133.69063 1.03833 93.2940 29.1000 .50
22412.00 315.30600
2.04805 85.1287 28.2000
.50 8416.50 230.75127 1.70838 72.0679 26.1000
.50 4751.50 176.05497 2.07411 82.9848 28.2000
.50 22412.00 240.82333
.93136
C8 Sulfonate 22.3976 19.2000 1.00 112.20
13.51821 .40268
22.8766 19.8000
.50 370.10 14.90438 .11595 23.8737 20.5000
.50 759.20 16.63157 .10826 23.1245 20.2000
.50 564.30 14.98843 .11121 23.5038 20.6000
.60 238.90 14.55838 .17176 23.3571 20.2000
.50 759.20 15.50915 .06010
2008 West Virginia University School of Medicine
Median C8 Concentrations for Education Groups
40.00
"GendelJJ .Female
IiI!IMaie
30.00
!:ls:::: 20.00
..'5
"::iE
10.00
0.00
No Response <12 Years HS Diploma or Some College Bachelors
GED
Degree or
Higher
"Years of School Completed'"
Median C8 Sulfonate Concentrations for Education Groups
30.00
"Gender'
IIFemale
IiI!IMaie
~'il:: 20.00
l::
of :;
VI
..!:l
l::
l10.00
::iE
0.00 No Response <12 Years HS Diploma or Some College Bachelors
GED
Degree or
Higher
Vears of School Completed"
2008 West Virginia University School of Medicine
Population Results for C8 and C8 Sulfonate Plasma Concentrations Stratified by Household Income
All Age and Gender Groups
Case Summaries
"Average Household Income"
<$10,000
Mean
Median
Minimum
Maximum
Std. Deviation
$10,001 - $20,000
Std. Error of Mean Mean Median Minimum Maximum Std. Deviation Std. Error of Mean
$20,001 - $30,000
Mean Median Minimum Maximum
Std. Deviation Std. Error of Mean
$30,001 - $40,000
Mean Median Minimum
Maximum
$40,001 - $50,000
Std. Deviation Std. Error of Mean Mean Median
Minimum Maximum
Std. Deviation Std. Error of Mean
$50,001 - $60,000
Mean Median Minimum Maximum Std. Deviation Std. Error of Mean
$60,001 - $70,000
Mean Median
Minimum Maximum
Std. Deviation Std. Error of Mean
C8 57.1410 22.1000 .60 1979.50
115.66904 1.34029 67.8230 24.8000 .50 2590.80
145.93333 1.55610 78.4169 27.6000 .50 3190.60
161.48672 1.68124 82.9654 29.0000 .50 7534.60
189.60938 2.10249 79.1755 28.5500 .60 4751.50
167.34416 2.05986 98.5455 30.6000 .70
22412.00 399.48548
5.35752 121.5587 35.1000
.50 17556.60 468.06639 7.05556
C8 Sulfonate 20.7658 17.9000 .50 291.50 14.39424 .16724 21.8999 18.8000 .50 585.20 16.17785 .17296 23.3989 20.2000 .50 274.90 15.00223 .15649 23.9769 20.7000 .50 564.30 16.94342 .18826 23.9217 20.9000 .50 272.00 14.75490 .18183 24.3102 21.4000 .60 289.40 15.13852 .20333 24.6619 21.8000 .60 225.00 14.49264 .21891
2008 West Virginia University School of Medicine
"Average Household Income"
>$70,000
Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
Don't Know
Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
Total
Mean
Median
Minimum
Maximum
Std. Deviation
Std. Error of Mean
C8 105.9631 35.8500
.60 8416.50 307.99547 3.34738 75.9945 27.8000
.60 3713.20 155.38809 1.71274 82.9848 28.2000
.50 22412.00 240.82333
.93136
C8 Sulfonate 24.9478 22.2000 .60 207.40
14.38888 .15663
23.1615 19.6000
.70 759.20 16.83009 .18580 23.3571 20.2000
.50 759.20 15.50915 .06010
50.00
40.00
~..s 30.00
~
~
'ij ~~ 20.00
Median C8 Values for Household Income Groups
"Gender" .Female IIMal'
10.00
0.00
"Average Household Income"
2008 West Virginia University School of Medicine
Median C8 Sulfonate Values for Household Income Groups
"Gender"
30.00
.Female IlIIMaie
..sE
til
20.00
~
C
:o;f
VI
()
'"c '"l10.00
::;;
0.00
2008 West Virginia University School of Medicine