Document rxpvD1xXZXnjb56jq4mqXbBNJ

November l6, 19^0 .V Dr. 3V U. Buchanan Republic Steel Corporation Youngstown, Ohio Dear Doctor Buchanan: W are sending herewith the analytical report on the four samples you sent us. As Dr. Kehoe is out of the laboratory and will not return for some time, I am commenting on the results of the analyses and stipple cell counts and am leaving this letter for him in the event that he wishes to enlarge upon the following observations. The stipple cell counts were as follows: - H- per 50 fields per 50 fields 0 per 50 fields - no smear As Dr. Kehoe has probably pointed out in his dis cussions with you, stipple cell counts find their chief value as an index of exposure only when used for large groups of men and as a continuous frequent record on an individual. In other words, a single stippled oell count on an individual at one time does not furnish the accurate information that can be gotten from study of the excretion. The variability from count to count.in an single man or in a group is high and it is only by consideration of the mean values for groups that the effects of this variability can be eliminated. Again, while subsequent counts on a single individual may vary, a progressive rise of tendency to inorease, wbuld be indicative over a period of time of greater and greater exposure. It follows therefore as a consequence of the high variability of stipple cell counts, that correlation between them and urine analyses would only he feasible if a large number (sufficiently large to eliminate variability in counts) were obtained. In a small group, variability would obscure any contingency or correlation that might otherwise be present. The experience with large groups with varying lead exposure with its effeot upon stipple oell counts and means for the grqup is included in Dr. Kehoe*s recent publications, copies of which you may have. If not, the collected papers of the ' rjrZ& ,f< ' 1 .'r,,r ; ; \. f Dr. X. TJ. Buchanan - (2) - November 16, 19hO national Battery Manufacturera Association meeting in Chicago, in 1939 cover this subject, well. Spot urine analyses, since they are carried out on small samples, are more variable than large 2 ^ hour samples, but if there is no forced or abnormal diuresis or concen tration of urine, they check well with the large samples, and have proven extremely useful. Much greater care is necessary in their collection, of course, since very small contaminations will greatly influence the results. Because of the possibility of contamination, large samples taken at periodic intervals to measure the exposure of groups,, have in the long run been freer from conflicting incidence and susceptible to more accurate interpretation. These need not of course be collected at the plant, but may be taken at the time the workman is at home and the Jugs left in his possession until a 2 or 3 liter sample has been collected in the off hours. In our experience with adequate instruction and reasonable care, large samples can be collected repeatedly without contamination. In the light of v:hat has been said above, the interpre tation of the stipple cell counts and the urine results will become somewhat olearer. In so far as the counts are con cerned, these are no higher than those seen in non-exposed individuals and should be interpreted in terms of pervious counts on these men and counts on other workmen with similar exposure. of the urine results, only one, namely, that onIB p M W B H H B Bpp is at a level which indicates significant exposure,.I n l a r & e g r o u p s 'of men having a mean urinary exoretion of this value, only occasional oases of intoxication appear and this level itself is not of an order of magnitude which Is associated with intoxication in a given individual. value of 0.o6 for f l H H H P and 0.06g for higher than thSse encountered in normal Tndivi- '^HaTsand.suggest recent moderate exposure, which may or may not have been industrial In origin. In the case of none of the samples, however, Is the magnitude of excretion of such order fes to suggest serious exposure. With best regards, I am t-, Very truly yours, KE 0018655 Willard Machle,"*i. D . . -V '1J:''Hf' ' - ^ i* - nth & yea*. Heats IMA made x p o s o m o f urn-t o 4v&l .t s i a t s d ssssl JUUS 1838 -i -i ;.- ,,; ` . ihiy :i38 ss ; -:$&zir212. |4g. 1938s 213 % 3 15 9 MO 14.5 24.0 44.1 , -\.. ' HV* V\ft. : .\ ; ' . 'v - . .;iL l a r n m t h oa days that - - biinfi siede 1954 2020 2000 15.7 0 " I, 14.S 36.8 19 32.9 0.3 44.0 20 S4.S' sept.1933 . 2f0 -16 18.0 ` 93.7. 67.2 53.7 56 53.5 \ Osi. 1938 633 36 19.0 ' 105.3 93.6 106.3 18.2 31.6 ' 30V. 1933 456 35 13.0 , 103.8 100.5 1258.4 96 96.6 Dee* 1938 135 13 10.4 31.6 26.7 23.9 8 26.7 Jan. 1939 51 10 5.0 30.0 .15.3 30.0 0 16.0 Feb. 1939 93 15 6.0 43.4 43.8 63.0 39 51.8 3ar. 1933 164 20 3.2 68.3 70.0 95.7 72 79.7 dpr. 1939 191 23 8.3 ' 62.6 57.0 71.0 48 74.7 :iay 1939 jJhneli338 103 239 is 6.9 29 10.0 34.8 121,3 42.0 73.4 61.3 13 107.1 83 58.0 43.9 The abfers is all the record thatis available on the moa whose check numbs? is given. As there is three turns to a full 24 hours of operation the above record is very inaccurate as it non stands, a approximate amount of exposure time oan be calculated by uividing the hours worked each month by three, assuming that the 0144 was divided equally among the three turns and that the time also was equally divided. If this is done the time should than be multiplied by the degree of exposure according to,the kind of position the man fills* This degree of exposure has been estimated by the superintendent of the Bessemer and is given below with the mens names end positions. 0k.Ho. Position Segree of exposure 2001 Pouring floor 1*0 1991 Steel poorer 0.9 1954 Vessel man 0*3 2020 .Labor, 0.3 '. 2000 Pouring floor 1*0 ........... B>te: An exposure of 1.0 means that the man gets the full exposure to the fumes. Any less amounts meaning a decrease in the exposure to fumes due to the mans position* The men listed below have not baan exposed to mSA treated steel since Sppt. 1939. Ho record of prior exposure is available* Ck.No. Name Position 5818 Scarier 6179 Soarfer 6300 Scarier The men listed below are from the Bessemer converter and finishing mill and no record la available oa them prior to July 1st. 1939 Ck.No. Has Position 1886 I 1920 Bottom maker Scrap wheeler UZ 0018656 %'$low is a report covering the months of July, August, September 1939 on exposure of the aea listead to DMA tyw^tejimteel :btel Sup'erintea- ant of the Bessemer^ Mam ( Pposiittiion Total, /Average 'ee of 1st. total t > fume\imi! sure exposure V fnae time per ti 5SV0^hrs 16 his. V o . o 0 brs. '1920 Scrap man 28 50.8 " 1.8 0.6 30.5 * 1954:. Vessel man 33 34.3 " 1.0 " 1.0 34.3 " 1991 Steel pourer 35 34.0 * 0.9 * 0.9 30.6 * 2000 Pouring floor 32 33.3 " 1.0 * 1.0 33,3 w : 200.1 2020 Pouring floor 28 Laborer 8 28.0 " 9,3 ** 1.0 " 1.1 1.0 0.3 28*0 " 2.8 . 2348 Guide setter 15 20.6 1.3 * 0.5 10.3 * *Last worked Aug 23, 1939. off thereafter due to vacation and sickness. Mote; Exhaust system was put into operation December 12, 1938 Lead adds to moulds beginning March 8, 1939. H. J. Elliott Medical Technician M. :'.- A : c-' ? .^'^4 KF 0018657 l8S#: Examinations of Employes of Republic Steel Corporation. Bess Hospital, Youngstown. Ohio #19sk f l H M H H V #e58lS mmmm MHHIIP ^ #2001 # 10qi W B B H B H p p - #1920 ____ 3i k 6 M #2020 , .#6179 Analysis Number URINE Mgs Pb Found 39A-25I4.7 _ 59A-25k 5 _3.9A-.25te.. _ "3 9 Ar25kk.,,. .39A-25k 9 ;_39A - 25k 5 _ 39A-2550 39A-25k8 . . 39A-25.&1. 39A-25k 6 0.0s 0.13 0.21 0.32 O.28 0.15 0.11 0.17 0.06 0.l8 A*J Mgs Pb/Liter r* .. . 0.02 . 0.0k + 0 3 0.08 + 0 0 .1k _u _ 0.09 1 0.05 L 0.06 9 0.06 0.02 + 0.05 + k /<? % Reported: August Ik, 1959 HE 0018658 N19711.02 Sample of -arine submitted by Republic Steel Corporation, oiaugstwn, Ohio. Urine Date Received; 7-20-1939 Analysis No. 39A-26^7 Volume - I7S0 cc Mgs Pb/ Liter - 0.03 S ? KE- 0018659 Reported; 7-22-1939 N19711.03 STPPEED CELL COUNTS ON SHEARS FROM REPUCLIB STELL CORPORATION Received 7-19-1939 #6300 #2020 6 19 KB 0018660 V-'V<^>'"'.''' - -5 : g T^ .r .^ j ' c `-' v -: i ...,_ r/Stippled. Oell ftounts t. j ' ' 'on; \ Smears from Employees of Republic Steel ' :J, i$ J?f '' ^'' ' 3^.fiUir. 0 vXiitijjT ife ii' .^ _y ;-fi:4rJ 11 \ .#..*.?..* Shea results are well within hojmsl limits* Robert A. Keho# M #D, fV'>v/rSi,| r-$:.'itfc ' i/J t ^'|.` Vt RE 001866 ,.. *rAA."L?