Document rxYb34261xZZEYBVLR31ROB1E

~ Katherine E . Reed . Ph .D . Staff Vice President 3M En~ iron mental . Safety Operations 0 7 0 6 - oo Health and / 3 651 1 yUU Bush .~~enue . Bu~idip PO Box 3333 1 St . Paul . MN' 55133- 333 I 77A 433 1 A 36 E - Certified M~ ail- -~~~~ June 29, 2006 1i~ Cr 1 ~~~~~ Document Processing Center EPA East - Room 6428 Attn : Section 8(e) Office of Pollution Prevention and Toxics US EP A 1200 Pennsylvania Avenue NW Washington DC 20460-0001 i II ( EI 111111111 1 IIII~i 11,1~!I1 IPI IIIII IIIII I IIIII Ili Ili 9 h 0 0 u () 3 Re : TSCA 8(e) Substantial Risk Notice : Sulfonate-based and Carboxylic-based Fluorochemicals, Docket Nos . 8EHQ-1 180-374 ; 8EHQ-0381-0394 ; 8EHQ-0598-373 - Pilot Study to Assess Serum Fluorochemical ConcentratUiQN- i n American Red Cross Blood Donors, 2005 . Dear Sirs : -~ 3M is submitt ing this notice to supplement its previous submissions on sulfonyl an d cafb oxylt=' based fluorochemicals . 3M has recently received the enclosed fi nal report for serum " fluorochemical concentrations in a small sample population of American Red Cross bided donors in 2005 . The purpose of this pilot study was to determine whether general population PFOS and PFOA concentrations, as measured in 2005 in a small sample of American Red Cross blood donors, may represent a decline fr om prior general populations measurements made in 2000 . The study found that there was an approximate 50 percent decline in serum concentrations of PFOS and PFOA consistently observ ed across sex and two age categories for both PFOS and PFOA . 3M does not believe that these data indicate a"substantial risk of inju ry to health or the environment ." Neve rt heless, 3M has decided to report these data, recognizing the ongoing work by U .S . EPA to assess fluorochemical exposure pathways and potential risks . If you have any questions, please do not hesitate to contact Dayna Blomquist at 651-736-5413 . Sincere l Ka erine E . Reed Staff Vice President Environmental, Health and Safety Operations ~