Document rxL2r3p25LJzyBkXKZ14Kpv60

Mr. 8. Vhaaloek-S t. i-ol Mr. vui Logu#-3t. 1x5ult Mr. 0. t* fru*kl-Blrmiagh*a / Mr. A. W. Tovac, Mr. Pleaborgao- 3t. Doui* Aim 17, iy4 Dr. X. V. Lack* 0. 8. Dopt. of Afrloultur* Toxaa Xxporlmatal fttatlon Box 232 larrvllla, Tmu Door Doo tor LacJcot v . Aroolora ud JIB-40 During o roooot trip to M^ohlMltoo, vo htd opportunity to ill* ouoo vlth Dr. X. X. Jtalpllng tho work dooo vlth Arooloro orlcado, florid*, u louololdoo, altlaldos, Urvloldo* tad vaqulto ropollonu |1tm in tbo 082U Aoport X-733. Particularly th# lovor ahlarla*t*d Arooloro, laoludlag Aroolor 1248, ahoood proofs In* rooult*. Our thought* 00000m Un poooiOlo us* of liquid Arooloro ao *a auxiliary aolvoat for DOT and otbor iaaooltloldoo la various fonailatloaa. Booouoo of thoir uauoual oMoaiool stability, tho Arooloro aay tiro loator laotlag valu* a* altloldoo tad larvloidot th*a obtained froo tho otbor toxicant*. a oooordaaoo vlth Sr. Xalpllag'a suggoatiooa, vo oro f Tailing ,ov vlthovt ohargo oao gallon oaoh 0/ Arooloro .1221. 1232. 1242 and 124ft aad aloo oao gallon oXJflBsaftP. Our laboratory la *ob-'"~ jf dulod to dotomiao tho aolubillty of DDT la tao various Arooloro ' aad *l*o obook tho oiailar volubility la -40. It it our under standing that JBMo will dlaoolvo about 20 porooat by voight of DOT. SB-4 is ooooldorod to >0 rolatlvoly aoa-phytotoxlo. v# aro oaolooiac 00n Of otr Moooaato fOohaiool Dullatia Mo. P-115 dooorlbiag tho ajgloal ooaotaato of tbo Arooloro aa glvoa % oa pogoo 4 tai 5 of talO; bulletin. Vo aro aloo oaolooiac a oopy of our BulloUa lo ?-10b, fivlac tbo phyoloal ooaouau for 0*40. Tho follovlac a--atta vlll ladlo*t tho toxleity of Aroolora *ad BB-40r Tbo toxicity of 9-40 9aa adaiaiatorod orally to rabbit* aad rata, la lov cad practically laalgalfleant. Qhpvbliaaod oxporieatal roaulta roportod froa rollablo aourooo ladlo*to that rau aad rabbit* survived alada doao* of 2$ grans par kilograa of body volfhi* A*ta avrvlvod tho dally feeding of quantities HONS 087737 WATER_PCB-SD0000026723 Pag* 2. equivalent to 6 grna* per kilogran of body might over period of four Booth*. lomver, tho animal* failed to galo might it c normal rate, lo Indication of jo* deleterious offmt froa *uoh large dosages of tho material. Th* toxicity of Aroolor* appears to vary considerably with reference to th* individual ohlorinated blphesgrl or terpfeenyl oompound. Pro* an Industrial aU-odpoint, tho gro*tott ooooora d*ni* vl th tho vapors omittod froa Aroolor dm tho materials f.r* hoot*d to higher to^truturoo. Tho vapor* of tho lomr ohlorinated Aroclors should not bo breathed, and it is bollovod that obout 0.5 ag. per cubic meter of air lo tho msxiaum amount permissible for safety in workroom*. lomver, in tho otac of mor* highly ohlorinated Aroolor*, such as Aroolor 1266 vtiloh 1* 68 peroent ohlorlaatod biphenyl, this mtorial has boon reported froa reliable oouroos as being relatively non-toxlo. v hut* hid ocoaslon to study tho poeelble dermatology of Aroolor 5*60. It vns determined by the ekln patch toot procedure given by Dr. Louis Schwarts and Dr. Soauel M. Peek in Reprint Bo. ?5Si* from the Public Health Reports, Vol. 5i# Bo. 17 (April 26, l^M) that oat ton febrlo coated with Aroclor 5*60 and an oil modified i<lkyd main in such e manner thnt etch square Inch of fabric contained 10.5 ag. of Aroolor 5*60, was neither a skin irritant nor * eonsititer. you probably know, alllions of pounds of Aroolors are used .-'imu'.lly In n wid* variety of Indus trli 1 appllcr.tions. in this connection, when the Aroclora re used .'t normal teaterfture* vt have not hod any report* about toxicity h**rd* arising. Believing th*.t you will want to know (.bout the selling prloe for Arne lor*, v* quote th*a* product* at. 18 cnt* pound in car lot ou ntity, f.o.b. Monsanto, Illinois or Anniston, Alnbt-mt<. HB-*-.i Is quoted at 17 oents a pound in t*ink care and 18$ oente in lose oar lot--drume, f.o.b. Anniston, Alabuar.. Doubtless you and lv. knipllng vlll hove in Bind soae speolflo (ppl lo'-tlons oonoernlng th* /.rociors and Hb-*0, no wo vlll ppprecltt# it if you will k**p ua posted along th*** lines and pl*a* l*t us knov vhether ve c/.n b* of assistance to you with th* 'PPllcation of tho** siht*rl; li. Yours very truly. c : lfr. f . 1 . Knlpllnf v ti.iurtnu, D. c. f. C. Benignu* Dev*lopasnt Department HONS 087738 WATER PCB-SD0000026724