Document rx8x1rRGeEmdBEeaXa16KGnra

February 21, 1939 Hr. j. H. Schaefer Ethyl Gasoline Corporation C hryeler Building Hew Xork City New York Dear Hr. Schaefers** X am sending you herewith a few notations whioh % have made In response to the questions raised by Mr. Osborne of I.C.Z* Xn as much as I do not know where to address Osborne* I should appreciate it if you would forward these comments to him. You misfit* at the same time* convey to him my regret that he could not visit us* and my pleasure over his very kind note* X hope to have the pleasure of meeting him again and I wish to assure him* and his associates* that X shall be only too glad to give him every possible assistance. Sincerely yours* RAKtifl Robert A. Kehoe, M.D. 0010108 q u so t iph s IIL fmATIOH TO. MEDICAL OOI3TBQL 1* Containers for collnoting urine, blood and feces, and needles for the collection of blood, should be supplied to the plant medical department' from the laboratory in which the analyses are to be carried out* It would not be possible, otherwise, for them to be available in a proper state of chemical cleanliness. The.first requirement, therefore. Is provision for such an analytical laboratory, This laboratory cannot be operated within the plant unless the most rigid pro-* cautions are taken against contamination of the laboratory space and environment with lead compounds, through isolation of the analytical rooms and by adequate filtration of all air entering them. This, in my experience, is quits difficult of accomplish ment, and X would recommend that a laboratory for this purpose be situated at some distance from the plant. Dr. S. 0. Dodds, of the Oourtauld Institute of Biochemistry at the Middlesex Hospital Medical School Is in position to advise with respect to the personnel and facilities which will be required for setting up a suitable analytical con trol.. 1, also, should be-glad to give say further assistance which may be required. The point which should be made at this time is that the analyses of biological materials for lead cannot be done in accordance with customary chemical routine in plant operations but, if it is to be of any value whatever, it must be done in a special laboratory, designed for that purpose, by specially trained personnel. In all probability, from three to six months of training in methods of analysis and In obtaining KHeoioioo OOIOIO^ and handling samples for analysis will be required to develop adequate .personnel*'. The location and equipment of the analytical laboratory should be determined. In part* at leant, after the . / selection of the person or person who are. to do the work, . 2. t m at some loss to understand the origin and meaning of the question relating to a tarpaulin shed for. cleaning a workman who nay 'be contaminated with tetrai ethyl lead or Ethyl fluid* Any mm who might be splashed or otherwise Wet with such a liquid should be washed thoroughly with kerosene and then with coap and water immediately, dontaiaers with kerosene' and emergency shower bathe are scattered about in various parts of the plant. These would be used promptly in case of accident so as to wash away the liquid lead compound before any appreciable absorption could occur. In view of the danger associated with delay, one would strip off Ms clothing at once and clean up with or without assistance* as circumstances indicated. mmsa a Ka to mim. p o ix o t io h The lead concentration in a stream used for general purposes and flowing through agricultural or urban districts should not be pe.Httitted to exceed 0.1 mg. per liter of water* . Even at this concentration It Isaaeuraed that the lead exists mainly m suspended material and. not in. solution, so that filtra tion or settling would result in considerably lower values. The permiss&bld lead content of the ^flashes* referred to in the report will depend Upon the degree of isolation of these flashes and the use to which the water mi^it be put. Moreover the K07I0T00 o I o I / 2> extent to which the lead will precipitate out 8 sulphide will depend* obviously* on the acidity of the reaction mixture. It would appear that some means ai^ht be developed for producing approximately optimal conditions for this precipitation* whereby the clear supernatant water might be made substantially- lead free. . Signed* ItofoertT &. $ehoe*. k .d * Mreotor* 'Kettering laboratory of applied Physiology College of Medicine Cincinnati* Ohio