Document rpd66grDK1qKkjz8ZQBy0zx1v

FILE NAME: Johnson & Johnson (JAJ) DATE: 1975 Apr 17 DOC#: JAJ098 DOCUMENT DESCRIPTION: Letter to Dr. Hildick-Smith, J&J from Barry Castleman 3110 Main Dining Hall College Park, Maryland University of Maryland (301) 454-5601 MaryPIRG MARYLAND PUBLIC INTEREST RESEARCH GROUP, INC. 20742 April 17, 1975 Dr. Gavin Hildick-Smith, M.D., F.A.A.P. Director of Clinical Research Johnson & Johnson New Brunswick, New Jersey 08903 Dear Dr, Hildick-Smith: Several years ago I received a letter from you (September 19, 1972) in response to my concern that talc per se may be a * carcinogen. You referred to several ongoing studies, and I would like to receive prints or reports of any that have been completed. I would also like to know of any new literature (1972-- ) in which cohorts of talc-exposed individuals were followed up for mortality, any case reports regarding the possible carcinogenicity of talc, and pertinent animal studies. Specifically, your letter mentioned: (1) controlled studies on hamsters inwhich talc was introduced into the lungs and pleura. (2) separate, extensive animal inhalation studies with talc (3) an extensive epidemiological survey of the cause of death in a group of talc-exposed workers (4) other studies on the mortality of talc miners. I hope this request is not overly burdensome. As one who is sometimes asked about the health effects of- talc, I try to keep as up-to-date on the literature as possible. Sincerely, BC:ljk Barr/ Castleman Environmental Engineer V BWf - Protected D ocum ent-Subject to Protective Order 1 Of 1 JN J 000261538 Pltf JNJ 00038617