Document reyXQpJwpJNz6OB1mdqvxnpKE
Air Hygiene Foundation of America, Inc. * 4400 Fifth Avenue, i. Pittaburgh, Pa*
June 8, 1938
REFEESJfCBS 70 REC2NT LI1 * -%t\
OK INDUSTRIAL DISEASES
(A) Newa^\ js
7 KIXBS TOR LEAD PUCES,
circular, have announced the spirator for protection against
mercury, manganese, arsanie, of this type to receive
U. S. fpersoids, zinc, ate* ral of the Bureau*
OHI A w publication It )u? to ba issued educational aatarlal o contains itos on the reporting of occupational tarest.
nt of Beelth, Columnua. 11 contain informational and _ era* Tha first issua, April 1939, of tha department, mobile laboratory,
.toss of general ia-
(B)
438 NOTE OK AK 21. 202-3 (
^/Eil.Dunn. J. Xnd* Hyg. & Toxicol., '44\
A descrip'ttjp&fiAfires of a new cell
i^aunting iaplngor dust samples*
Tha consists of two parts, ona grojg^qniJoth surfaces, with a central
ici* glass plats 1 sm. thick, dloeter that the cell
gpproxtaately 0.25 ml. The ot
plate of optically
lished glass* Both are of "pyrex* _ ,
le cover glass, such
those now used, any ba employed as a corer^
call greatly re-
duces the loss of tine in cleaning and reconuntiac tha
Sedgwick-Rafter
call* Tha comparatively large sealing area prevents
of air into the cell
caused by evaporation of tha. liquid/ Although no
te data has been collect-
ed to compare counts using tha new'.cell with that
Sedgwick-Rafter, rou
tlna plant studies her* confirmed its apparent aooura
ghs call could also be
easily adapted to plankton, sewage or bacteriological
because of the
simplicity of design and resistance to attack upon autocl^^^teriliration.
439 THE RATS 07 FRODOCTIOH AND THE PHEE SILICA OQNISir 07 THE ftf^UST PRODUCED H?
ROCK gmr.TTIS. A* Shaw and J.Q. Grahan* Trans* Instn- Min* Sagrs. London, 97,
104-15, (April 1939). (British).
Tha free silica content of fins dust is almost always less than that.of the rock
from which it is faimed. It is dependent also on the rate of drilling, being
9 slightly higher the slower the rate of drilling* The free silica dust produc
tion expressed as gras of dust per foot of hole drilled may be taken as an in
dication of tha silicosis producing character of tha rock. The resulta indicate
that all rocks from which mere than 25 gm* of free silica-dust are formed per
' foot of hole drilled ahould be considered harmful, ad that preeautlone should
than be taka.
.
2 PLAINTIFFS
i EXHIBTT-
References to Recent Literature - Z
440 SHICOSIS AND nS FHETfifTXON. X. S. Haldane, ? Haynes, A. Shaw end J. Q,,
Graham* Trans. lasts. Min. tegrs. London. 97, 40*67, {April 1939). (British).
It is suggested that the toxm silicosis be applied only to a fibrot1c condition
of the luags is persons with aa exposure to dust containing a high proportion
(50 or more) of free silica. Clinical aad radiological examination should not
be regarded as sufficient basis for a diagnosis unless there is a reasonable
history of exposure to free silica dust. Although a large nunber of coal workers
in South Wales hate been certified asmSlicotic, the work-histories of the cases
show that the men hate not been suhi^obad to highly siliceous dusts. The phthi
sis. #a$h-rate among the coal mis6&)an shown by their statistics, is not si
nif: naxfx population of tha district. The hi<
cide:
miners should not be attributed to silcj
as has
past. It is emphasised, however^Mt\tbe''in*
halation
of any dust will causa pulmonary daaMa^Tollow-
ina the
es of interesting discussions by otJaCfcaiSBrities in
the field. (above)
states that tha authors' deflnif&nA^r^sillcosis as proved cases of siliC9fls'^South Africa have
bean
, tha paper con-
trib
disease.
.
441 GP THB uvnr
Office, London, (1939)
Among tha larga lumber
directly with industrial
silicosis clinically, bu
cosis is compensable
sis in South Wales,
alttee on Toxio Solv
ers, checks at
age th^ toxic!
ducad. Mantl
of a public*
toxic solv
ing q very us
es along-4 d^kSflal health lines are
1937*8. H. M. Stationery
in this report are seme dealing coal miners, which resembles not compensable, whereas silicontlnus the study of anthraco-
on is the work of the CornAssociation of Chemical Mocufactur-
new solvents that are introzee the literature on
Other less Important research-
0? "CCRIOUS BODIES" IK T&S LWQ&Xl SOCn^AVHICAN GOLD MINERS. J. Path. 4 Bacteriol., 48, 47^^Ular^^K^). (British).
Lous bodies* is the tea often applied t6^ th> pec*$ittv structures found in
>asbestotlc lungs. They are light colored, but^imilar m ones have been found in tha lunge of coal miners. Tha author rsgbpts bratffly on such bodies
seen in the lungs of 3 South African gold mlaers'^hn:>has examined. Both light
and dork colored bodies were found, and In seme lunge^Both types wore present
simultaneously. There was no constant relation, however^ between the presence
of bodies tad silicotic findligs, and Dr. Wlllias Is S^p^that tha bodies are
not significant in the development of anthraco-sillcosis
he coal miners and
triaaers she has sznlnsd. They are probably the reeult oiSds^anfie inhalation of
fibers or spicules. These black cored bodiea evidently camfctr be produced ex
perimentally, although tha pale asbestotlo ones can be.
443 THE PRODDCnoM OP DOST IN SABD HEADDOS AND MEANS POB ITS SUPPRESSION. J. Graham, D. G. Skinner and W. H. Walton. Trnns. Instn. Min* tears. London. 97,
83*103 (April 1939). (British). Experiment* are deaerlbed which illustrate the eoneentratlons of dust in the chief operations inrolved in the driving of hard headings, namely drilling, shot firing end filling. The most important means found to reduce tha dust was the use of wet drilling methods. The use of a mist projeetar, with a wetting agent in the spray water, was only slightly successful.
References to Recast Literature - 3
444 A DEVICE FOR AHRESTOtJ EXPLOSIONS. Q. Allsop* E. I* Hartwell cad R. V. Wheeler.
Trans. Insta* Mia* Eagr. London. 97, 20-39 (April 1939). (British).
A description la given of arrangements whoreby firedamp explosions la coal nines
can be extinguished. The arrangements involve the provision of (1) mortars from
which a cloud of incombustible dust can be projected into the path of the explo
sion* and (2) thermal relays which* when subjected to the heat of an explosion,
close an electric current which operal the mortars. The incombustible dust
found most effective consists of
n salt, 180 chalk and 20 magnesltaa
carbonate. Tests made with the
have proved its effectiveness*
445 (April To the boea a mo
fortunate portent oc Anaconda sins
Daly. Min. Cong. 7., 25
blcm of Industrial haalth Is not newg^JdJitff always factor In his costs. Tho natal minlgcjMSstry is ;th acny other industries* in that^fe w&Pbut one in
anely ailieosls. The authoi^Aaagor of Hines, traces the dust ccmtemNaeasures of that company
,918. The paper gtx0\3ebd broad discussion of ts control.
446 TBE XXJ3I FBO
18-19, 72-4*
(May 1939)
Dust control Is an
trial engineering management and
should ba given coaslderat
aace has baea gained during the pest
and industries have found
control of the duet problem has not
been prohibitive* Coasid
Ten to duet* whether hygienically
significant or not* y^lhk^aign
dings or new processes that may be
potentially dustyy? |Sr)/teats or '
uld be made at regular intervals
to check the
r of the systcrfsv.to
higher employee morale and
to find
hazards.
OEANXNO HET9DD6. fred
67, 44-6* 92 (Hay 1939).
ited description is given of t
the new cleaning depart-
a foundry* Small eastings are cl
leblast machine; largo
ttings are cleaned by first rtm ng the
of high pressure
Water, then blaetlng with steel shot. All
aryestis_gjK , wet methods and
the sludge is reclaimed* This modem installatoion3nia'ss naodv^'oinly almost elimin-
ated the dust hazard in the foundry, but has realigns saving of over 750 in
the time of tfrying cores in large castings*
446 PRACTICAL HTTFElOfi EQR THE CQJURQL OE SOTHCEC nFOSOBES^sfr. A* Cobum* Am. J.
Pub* Health* 29, 501-6 (Hay 1939).
The author presents a emery of the general consideration^, prevention of
industrial diseases. The hazards of dust* cbromlim* lead* agff other materials
ore discussed* The paper was presented at the October 28* 1938* meeting of the
American Public Health Association in
City* following the paper is an
&-page discussion compiled by C* L. Pool which siHarlzes and describes typical
methods for control of exposures in certain Industries*
449 BEYOND TOT THE LETTEt Of THE LAE.* H*J.fioberts. Occup. Hazards k Safety,
l> 15-18* 28* (Hay 1939). The tread of court decisions is definitely towards application of the eoaston
law, of considering an occupational disease the seme as an injury, wherever spe
cific coverage has yet to be enacted. Cases are presented to show the devious reasoning by which the courts have made awards for industrial disabilities and to show management why it may ba wist to look beyond the latter of the law la determining its responsibility.
Reference* to Recent Literature - 4
490 AT.T.AYTM5 DUST IN' BITOCIJOUS-COAL VINES WITS WATER. D. Barrington, J. I. Forbes,
F. S Cash, S. H* Denny* C. A. Herbert, 0. J. Parker, C. W. Owing* and a. w.
Hiller. U* 3. Bor. of Hinas, Tech. Paper, No. 993, 99 pp. (1939). For sale by
Supt. of Ooeusenta, Washington, D. C. for IS cents.
This bulletin describes more fully (see Abstract 116, 1939) the researches of
the Bureau of Hines on the use of eater in reducing dust in coal sines. To pre
vent dust explosions in sines both rater and dusting methods are being used in
conjunction. The dusting cannot be applied within 19 feet of the face, and it
is at this point where such of the cotdftdusts and gasea ore encountered. This bulletin esnorates the dust prodtwiAg?Sources and describes practical methods
of us&g water as one of the aost^BseeHve methods of
du3t in bli
:cellest lUmstrlproa* sad sketches are Included.
btcmTu its explosive qualities an Increase
Fs claimed in soso sines, due both to
increased visibility*
491 DZAOBSTCC tive Edltl; the Assocj This bnMl^fio outati nistrial
opportunity to detect at a proper diagnosis, health but also that of
)SIS or TBB LUNGS AND
DES. Tenta-
Losis Association, 1938*
tolnable from
W* 90th St*, New Yc
10th edition of
presents simply and
consider ln^dfeg&pxlig pulmonary tuberculosis.
Lnes large-rcani wT worloen has an uimminl
reuti
Let should help him in arriving
lee not only Improves industrial
492 TUB2ROXLOSIS HDBSAZJT7 IN IS&aSB&~P0PgUTX01B OF MASSACHUSETTS AND MICHIGAN.
C* C* Dauer. Am* Rev*
1939)*
Tuberculosis mortalitssrajgp DavV'beon hi^ey In four Massachusetts cities than
In a vial 1 nr grot^ottappzwdmatoly^tho ssme^dlzo in Michigan* It appears that
the difference i&JMtsiity in the teargroupn^^ cities can best bo explained
on the basia^ck*qri unfavorable envtaBrautal^4& social conditions in the
Mnssachua^rs^roups. It also appears^f&t indirectly the composition of the
populjti^b^with respect to nationality hms^syemeeme part in thaea differences
The paper includes tables sj^^natlerc^ which describe the data
age groins, type of oecupatlonx^i^slty^^sppulatlon and housing
____
______
_ N^^)j _
____
REPOST OF TEC DSPAROtOfEAL CnHITl'Jtt; CN CQMPBGASS^ FORWARD BOOM VOHOSS. H* M* Stationery Office, London, 1939. The Committee was appointed to consider on equitable^smpensation code for card room workers in cotton mills* For a long time it warn tfitaght that there was so specific disease among the operatives which could be thejsntojeet of precise clinical diagnosis, but the present CcKUtee rec^meadA^p)permission of workers to apply for compensation for a respiratory di*eaifemed "byaainoais," after having worked In a card rocm or cotton blowing room fS?20 years or acre.
It it now thought that a special medical board is able to arrive at a definite conclusion os to the occupational origin of this disease, which re*bles bronchitis and smphyssma and which is presumably characteristic of the occupa tion*
494 THE JLOW OF AIR AND ITS DIS3SIBOTI0N THROUGH DUCTS. PART 4* DOST LAYOUT. J. R.
Zwlckl* Seat* kYcst., 36, 48-90, (May 1939)* See Abstreot 378, 1939* This paper discusses the methods of duct layout and design besed on technically correct methods* All sections of the system are first calculated as equivalent round ducts and then their equivalent rectangular dusts substituted. If necess ary, to fit tbe structural requlrneats of the building* The designing is based on the flow in the selected main duct and branches are calculated es percentages of the main*. Equations for caiculatingduct sizes and head losses ere included and explained*
References to Recent Literature - 5
(C) Papers on Industrial Poisons, Cancer. Deraatitla. etc.
499 BSSPXRA20K? HAZARDS 07 XLBCTBIC ARC WKIHG. 0. A. Sander. lad. Had. 8, 177-80
(May 1939).
Twenty yoars of electric welding experience seam to indicate that the operation
is not a hazardous occupation provided the fume concentration is kept below a
certain Level* This danger level appears to be higher than the concentrations
of foea usually encountered in aodeafely large and fairly well ventilated
rooms. A great deal depends upon^tJS^iAteriala being welded and materials in
tha weeding reds. Hewer type* am^Mnslnually being developed and care shot
be in tha Use of thA2cmagr the newer materials are manganese.
of lead poisoning is of conaoquence
lag Welding should not be dona in confines sweets
le o]
rentilatlon even for short periods of^OTwi^Mn nufac-
of night well consider a progrA of rbaoa&n in the
ofN by the newer electrodes; a prq0fem3&thls sort would
ital industry.
486 SEAIi
L7S.
187-94,
?39)
it nay ha saf
shat oil.
s nay be potentially toric un
less definitely known
otl
ited that any ehAical naterial,
however toxic, can be
le degree of safety if its toxicity
is known and tha iadicat
a are followed. The author dlscuss-
ea tha hazards of toxic
portala of entry into the body, the
chemical and physical sta;
rch Aents aet and the organa generally
affected. A program 1
tha loown hazards and for eval-
uatlng the unknown
'of nasr,
The latter generally involves
leaghthy e
, uws.utirar illiyjr* With
to deteimine acuta and chronic
effects. A
tective neasu^ikfo
use of toxic materials is includ-
ed.
R. W. G. Davis. ChA. &
respirator is applied to any d
lotion to the respiratory organs of t __
ttnd (applying particularly to chAlcai^aejM)
are offered for the guidance of those who are^billed
equipment for vaiiue chAlcal processes.
c-^
(April 15, 1939).(British) e designed to afford
uses and limitations of alned. Suggestions select and provide
456 GASSING ACCIDDiTS. S. H. -Wilkes and D. Matheson. Chafe fc Xnd. 98, 316-23,
(April 19, 1939). (British).
The authors, a* inspectors of the Factory Department th^teland, hove tabulated
the reported gassing accidents that have occurred during
past six yoars* It
is shown that carbon nonoxide produces far aost accldeatb^fnA any other gas,
almost as assy as all others combined. other gases anoount^ed are hydrogen
sulfide, sulfur dioxide, chlorine, nitrous fiaes, innl s. benzol and trichlcr-
etbyleno, to Motion e fit. Accidents are cluud as those due to "expected"
gases and as those due to "surprise* gases, sad som of the aost serious acci
dents ero caused by the letter in locations where the gas is not manufactured or
handled, but is generated or encountered by accident. It Is noted that chemical
works do not produce a high proportion of the eceldAte, end that nost are in
the iron and steel trades, particularly the bleat furnace end its associated
equipment. Lenghthy descriptions are given of certain general precautions to
be followed.
References to Recent Literature - 6
459 WAS OASES AHD IND0SIRIA1 HAZARDS IN THEIR MANUFACTURE. E. H. Colo, J. R. DriTcr,
S. S. Bowen and 0. Cooper. Arch, Dexmat. k Syphilol., 39,, 45-54 {January 1939).
The authors were consultants In a factory in which diphanylchloroarsiae (DA),
ehloroacetophenone (CN), diphenylaaine-chleroarsine (HI), dichlorethylsulflde
(OS Bustard gas), and pbonyldiehloraraine (starnite) were prepared and which act
ed as irritonts on the skins of workers who were exposed. The procautions and
treamonts in the use of each arc listed. In general, the authors suggest the
following prophylactic measures: (1) abeolute cleanliness in the plant; (2)
change of verk clothes every 2 days; (Zk careful washing of hands and face before
each seal; (4) bathe and change to stnet clothes over? night; (5) use gas masks
in aljNoperetions where exposure (*^fcangErous gases is possible; (6) with all
proraja except Bustard gas, the wtouiag of rubber gloves and a Bustard 3uit<
(?) iBgniate treatment ofsroSjs ejected by DA or 01 with fresh solutio*ftf<
sodiua wpochlorl^^ A&&J$pict*<i by C3T should be treated with lO&^fcutfct of
sodiua dcafbonat*
'
460 THE DB'JflCTli
AHD VAPORS IH INDUSTR.
Cham.
k Ind., 58,
1939). (British) .
The sensed
ihavior of sniaals are b
{able as general
methods
>nco of traces of
is encountered in many
i^dflatrM atnoi
for slaple,
.-quantitative tests,
swuatrTM to very suitability of existj
>na of gaqgg
icusi
l^mpors is pointed out, and the icrlptlon is givsn of such a
method for the detect!^
of which have boen published by
the Dept, of Scientific
tsearch (England). Those published to
date have referred to
'hydrogen cyanide, sulfur dioxide, nitrous
fuses and benzene; all hnvex
La, these abstracts.
461 ihs ToxxciTr op o:
.,t$* Mc^gein. Own. k Ind. 58, 339-42,
(April 15, 1939)
Acute and chro
ng by vapore^nf o
solvents an described and ex-
aaples of poJ
n aan are givea^^The o
has been to stress the danger
not
to high concent '
the less frequently under-
stood.
exposures to low concefiggflons
earor realization of these
do such towards the applicatimrof
in the use of these sub-
in-industry.
jLorzhetric DsnsamiAXioH op hemoglobin as _ TIN, BASED OH KANT IHSOgTRIAL-gSDICAL BOARD TCmWTI'
_
OR AS ACID HEMAHuaperdinck.
Deutsch. Arch. f. kiln. Had., 183, 379-86,
1939) (German).
In two-thirds of 400 series of blood, the imnoglcw5?ynlues by Burker's hamo-
globinoaeter end the Zelss-Ikon hoometer (acid hmwa^were in agremeat. Occasional aeid hmatln values differod greatly from ^^e^by Burker's method,
probably because of wide variations in the course of fostinttoa of add hematic.
By Burkar's aethod, abselute hcaoglobin contest per erythigKEte showed very little variation in the 400 subjects. Of the total nmberf^Sjt had 5 to 6.2
Billion erythrocytes per cu.
463 CHRONIC CARBON MONOXIDE POISONING AHD FERHICIOOS AHB1ZA. 8. Bledeznenn. Folia
Haeaatol., 61, 166-200 (1936). (Italian).
1
A subject repeatedly exposed to carbon nonoxide developed hmatologlcal and
neurological syaptcas indistinguishable from those in pernicious anemia. The
rapid regression of the neurological signs under therapy lend the author to re
gard the signs of pernicious anemia as syaptcaatlc consequences of the carbon
aonoxlde poisoning, rather than as indicators of an independent primary perni
cious enema. It is suggested that some apparently refractory cases of perni
cious ansma may be due to unsuspected, repeated exposure to oarbon aonoxlde.
References to Recent Literature - 7
464 HETHDDS JOS TBS DETECTION 0? TOXIC OASES IN INDOSTST. NO. 5. UTIBOOS POKES. Dept, ot Sol* fe Ind. Research, Great Britain. H. M. Stationery Office, London, 1939. Nitrous fuse* are usually reddish-brown in color and consist of a mixture of I2 a2id NO4, with possibly traces of ND. Dangerous concentrations any be en countered In many important Industries. They are also encountered in connection with electro-plating, engraving, metal cleaning and photogravure processes, are foxmed during osy-eeetylene welding when the flame plays on cold steel in a confined space. They have caused fatalities during the heat troafiwat of metals in oolten nitrates. In ths test deHrlbed, one of a series for usa by unshille; . ths stalls is pumpe^^Sfcst9& a solution of a*naphth&lens and sul] Id in acetic acid by_a abaSard hand pusp. The amber of strobes
se-pinb color detszBines the coaeentratlc port in 100,000 (0.03 ag./l). Detail^vuqperip-
preparntions of tha reagents and ssmp2b it hods are
469 'ATS? IN GABBOK MONOXIDE F0I$$qpffT T. r. Bsli and
92 (1936).
two cases of "relwc&Eb carbon monoxide poisoa-
iTo lesions
the deeper cerebral
effimsa are tha basal lesions. Of
special interest is
Lmbftening of tha globus pallldus in
these cases since thl
t pathognomonic of acuta carbon mon
ofi.de poisoning. Aft
lesions ccmcnly found and reported,
the authors discuss tha
which have been preaented to explain
thoir development* They
union that no single theory seems
to be adequate to
the action, of this gas on tissue cells,
and that probably
r. Anoxemia, specific vascular
disturbances,
uliar blood supply in specific
parts of the
iculorly in the
are believed to act together in
producing
logical lesions fcos>und.
466 rAH0NS OK TEE POSSIBLE
07 OBTAIN 07 THE C2LCR-
1CAHB0HS WITH S0GGS5TI02B
iNCSfTRAJIONS IN TBS AIR
C* E* Drinker. J. lad.
J59JSV U, 156-9 (Kay 1939).
Jeriaents on tha tofioity of these
..a<$9^continued and are report-
cd in tha paper. It is veil known that a
ch t^calci is effective in
preventing acuta atrophy of tha liver from exposure to'>ggyhon tetrachloride. Tc
discover whether caldm in the diet would prota&^gainst liver damage from a
toxic chlorinated hydrocarbon, two group* of ratk^wery fad diets of high and lew
calcim, respectively, end subjected to inhalation high concentrations of a
mixtiffe of peata and hazachlonnphthalanes. It was uti|that %
calcium
diet has no protective effect against the character!stxcjivar lesions caused by
these compounds* To check a supposition that xanthine l$[$U&loa* reduced the
toxicity of these compounds, another series of animals weeHxpoeed to tbs
vapors, and part of than were given xanthine in addition* 'fib differences in
the effects ware noted* That the chlorinated hydrocarbons are broken up within
the body was proven by a significant increase in the urinary chloride following
inhalation of the compounds* Included in the paper is e list ef IS of the im
portant compound* of this series showing permissible limits of these substances
in air. Host of thm contain from 43 to 68J( ehlorlns; the limit of all with but
three exceptions, is.0*3 mg. per cu* meter of sir* The exception# ere: trlchlcr
naphthalene plus a trace of tetrachlornaphthalene -- 10.0 mg. per cu. a.; chlor
inated diphenyl -- 10.0 mg* per cu* m*; and tetra and pentachloraaphthalenes --
1.0 mg. par cu* m*
Eeferences to Beceat Literature - 8
467 TOSC EfJSCTS UPON BABBITS OP PIMTACHLORFHEMOL AND SODIOM FIHEACHLORPSENOL.
R. a* Kehee, W* Delchmann-Cruebler end E. V. Sitalllor. J. lad. $rg* & Toxicol.,
21, 160.72 (May 1939)
Pentachlorphenol is used coBercially as a preservative for wood and wood pro.
ducts* Since manual handling of treated limber cannot be completely avoided,
experiments on tha material wara earrlad out to shade the reported toxic proper,
ties of tha aatarlal* Tha substance Khan dissolved la capable of penetrating tha
shin surfaces and tha investigations
aada with this in mind* Pentachlor*
phesQ^ as wall as its sodium sal>^tii*?&bsorbed into tha tissues (cutanaousl:
sa&eousj in sufficient qi .ty, produces an acuta toxemia. The
doi ad cut#bualV, varied, depending on tha aolvent^ftg^a^;
it (is pine oil) to 380 mg* par kg
aoi tally usually recovered fully with!
cation that tha absorption of re
lisosisg* It. is stated, however
Ion and for this reason tha as
468 or
DZRT7ATXVSS
S* 0* Calvary, S.J.
a Toxi
'17M0X, (May 1939).
^excellent paper
ts
>ugh,
tha literature and reports on
an axtensive series of
compounds in detexmining thslr
toxlclties* Over 2600 a
tha tests and tha aathods of statis-
tleal analyses employed
resting. Aftsr eorrelating tha in-
formation in the literature
.ts of tha experiments, it is concluded
that ethylene glycol, dl
lens glycel mouo-ethyl-ether, di-
ethylene glycol ao;
hould ba entirely emitted from food
and drug preparati
should ba avoided except In very
small concentra PATS OP
___ IK THE 0
a? NC=>
tt and J* S* Johnston.
J. 768-70 (March 193
as identified in t
which repeatedly inhaled
doses of trichlorethylaae*
as a conjugated pro.
may possibly be a decomposition
complex unstable
und actually excreted* There are Indies
sms notarial is pre-
in tha urine of htaans exposed to trlchloret^Lane
470 TBXCBLOKSrBZUBB SBUASSO TA1S5 ASD TSSCB 3A7B
V* B* Harris, C. 3.
Ford, P* A* Patty and T. Hatch. Indust* Bull., H X* .State Dept* of Labor, IS,
132-4 (Uareh 1939).
.
This paper gives tha results of a survey of SO plants udlflfJtrLchlorethylene
degreasing tanks, with a detailed surrey of 18 of those studied* Saccsendatloas
are aada for tha design of equijawnt, location of eqoijmant^^cal exhaust vea-
tilatlon, and operation* Dimensions of tank and root, quantity of flow and ret#
of flew for adequate ventilation are given* Tha exhaust ventilation should be
applied laterally at the edges of tha tank since tha heavy vapor tends to roll
over tha edge and fall to tha floor* A ventilating rate of 60 c*f*a* par foot
of tank perimeter has bean found to ba adequate* Thin produce# an. air movaasnt
of approximately 20 f.p.m* toward tha exhaust openings at a distance of one foot
from the slot* It is necessary to keep tha rate of air flow as low as possible
to astntnjn efficiency of control sad to prevent too large losses of the sol.
vent*
References to Recent Literature . 9
471 TBSACHLORKTSaag IN TER TRttATVWfr or BDOSNOBC DISEASE WITH SPECIAL REFERENCE TO ITS TOXICITY. P. 8* Fernando, X. d'Silva, G. X. B. Stork tad 0. R. Sinnataaby. Indian J. Med. Rea., 26, 759-83 (January 1939). (India). Tetraehlorethylene, studied in 111 patients, was found to be effective in expell ing hookeozms; a single dose of 8 ce. for adults will expel 100 (as many as 510 wozms) but has little effect on round woxss. Careful examination of each patient was made in order to check the toxicity. Several liver tests were employed. No appreciable to^c effect on the liver was noted in any of them even in those re ceiving double the maximum adult doep^fn general use. No depressant effects of any importance ware noted and no tepno^ction on the kidneys. There was occasiaflaingiddiaeas. faintness and memmese but theaa were only temporary. A of d^eZ^ia thg^flmet effect!**. burtons of 4-5 cc. oan be given to adult; oa cjjilted are also discussed.
472
POISQNDO IN THE CAT.
s or
L. Stewart and JL C
Path. 26,
article in this s
Bo. 796, 1938.
divided into
The first re-
per kg;
ecood group, one or sore
dividod. Two weeks
trachlorlde as Croup I* Cats
als and the changes noted,
second group in the first 6 days
end of 6 days, tha Croup XX livers
igns of extensive residual damage in
lllrublnala, retention of bromsulpba-
se with ligation of ducts.
473 COMPARATIVE ACTION
ON THE VASOMOTOR SYSTEM OF
ANESTHETIZED D0GB5? V^harllor and Aagegot Ccmpt. Rend 3oc. blol., 130,
779-82 (1939U5ch).
P ''
NSW RESMOTOt SB TOXICITY OF 3SSBSfc&/ R.
Arch. Intern de Pharmacol.
et Theati&'4gr 123-83 (February 1939)%
describe Oautrebaado's eoTk v#m)
cal effect of "crystal-
cccmercial benzene* on the central
tha parlpheral vaso-
system and the ^ocardium, and presant^tWurei
similar research on
) tha toxicological effect of chemically purejoan2ei
) a comparison of tho
effect of cooMrcially and of chemically pure benZhns,
(3) the origin of the
greater toxicological effact of ccsmarcially _ ~
Experiments conducted
on threa organs (heort, intastlnes, and vasasotor
showed coemerciolly
pure ben2ene to have a greater toxicity than cbemlci
e benzene. Research
was than conducted to detezmlne the ccmpounds which ci _ this result. Follow-
ing the frnetionatlon of commercially pure benzene into*
rtaat groups, it
was fotad that the fraction boiling from 80.4 to 81.2C.
test toxicity,
greater than pure benzene itself. Further studies of this
tion and of the
impurities in the substance are to be undertaken later.
474 SDLTOHE1TED HZDROGEN PSOIXJCZD BY BACTSRIA IN A LEAD MINI. J. W. Sdington. J.
Hygiene, 38, 683-7 (November 1938). (British). Smarting eyes, markedly congested conjunctivas, end a stinging sensation in the nose and throat ware found in 12 workers in a lead nina. Tha strong mull of hydrogan sulfide in the port of the mine where they worked was traced to the stagnant mins water in which there were sulfur deposits. 3plea of the water yielded great mmbers of bacteria. Improved ventilation eliminated the trouble some gas.
Raferancs to Raeent Literature - lo
475 QfTOrCCATXOMS B? SBiZBiES. M. Duroir tad H. Deaoille. Presse med. pp 331-2
(March 1, 1939}* (Trench).
.
Acute intoxications, usually by accidental exposure to large concentrations of
vapors, cause the same injury ae do other lipoid solvents. The first symptoms
ere inebriation end vomiting but those disappear rapidly in fresh air. A more
severe font causes loss of consciousness or heart failure and death. In chronic
poisoning only tbs aromatic hydrocarbons of ths ben2n ring cause blood distur
bances. Impurities play a small role and benzine does not seem to attack the
blood. Methods of treatment and prophylaxis are given. If exposure cannot be
prevented by enclosure of the processor adequate ventilation* some other sub
stance should be employed. Last^brafte Trench Society of Btamatologlsts rej
that where they are not indispensable, benzenes must be prohibitec
476 FAATTAALL' fors.
During amounts none atrictlo: ular.
there was ,, but on
he suffered a again fall. This wa the slightest wamant. and the man died 6 hours the cheat).
%TTER BREATHING- HfDRDGBT SQLTIDE GASES/f
85, 1149 (1936). (Oexman).
<61*^
n sulfide gas the patient inhalmd^mSer small
ugh others in the laboratory cspQw3.7 exposed, The patient had a dizzy spell iagMffered chest con
' had Irritation of the tMjot .cough, weak and irreglirmii 111 n i. jlftrnSfr. vomiting. The next
vor was 126 ag.Jt. HO was
orders end actively moving st pains and the blood pressure fever end angina pains wart fait at
tment the condition became aggravated
pectoris (serene constricting pain in
477 EARL? DIAGNOSIS OT OCCSSX
_
KING.
Strauhe. Dautsch. med.
Wchnschr., 65,
(German).
In examining v^mjard^workers the author
.ttempted to distinguish between
arsenic absastafrw^nd arsenic pol
' .laves that those cases showing
only hratfnrabosia may be conaidored^W euff
arsenic absorption. The
proa|ad^ fflSnsy pearls, that can
on early stage by the use of
fLfcCm$&Itraviolet light, is charac
" .ttar*
ZXFZKIUBirS OH UDO CHANGES AFTER
S. Roploh.
beltsschuez, pp 144-6 (1939). (German)
The author, larestlgatlng the pne\monia produeii
a of manganese, had
rabbits and mica inhale dust containing 90
dioxide. Of 32 animals,
9 died within the first 19 days, all of which si
ire or less pronounced
bronchopneumonia. Of ths survivors soars were infect
.tranasally with pneuac-
cocci and half of that exposed to drafts and cold, survived, and it wms in these that the lung changea foi
a of those infected most pronounced;
those dusted only had no lung changes. Sines Thomas
as pneuBoola la
man also, a dust, containing 10 manganese dloAde to
the slag dust.
was used in continued experiments. About the aame results were obtained, namely,
that those Infected with pneumococci showed severe lung changes, that in those
sot infected the lung changes were not so marked. The author believes that the
pneiaonla caused by Thomas slag can possibly be traced to the manganese dioxide.
479 NOTES ON BOBBING KITH HROld POWERS. M. Deribere* Ann. d'^g. Pub. Induat.
et Soe. 16, 506-7. (1938). (Trench).
Bronze powers, which are composed of salts of copper are used In several in
dustrial processes* The workers, under the impraesion that these powders are
poisonous, tend to ascribe any sickness they experience to this cause. Large doses of copper salts arc indeed poisonous; but sueh doses seldom, if ever, occur industrially* The cogger salts grs rapidly eliminated and do not sat up &
chronic poisoning
the body.
Reftrences to Rscsst Literature - 11
480 Toncowat 07 7L0QRID6* A.* 0* Oettler and L. martrook. Aa. J* Med. 3ci., 197, 629*97 (May 1939).
The methods of detection and quantitative determination of fluorine la body
tissues are explained la detail aad the normal content of fluorlae la many of the organs la listed with both values from tho literature aad those found by
the authors* Very nail amounts of fluorlae are found la normal
tissues
(20 to 80 micrograms la 100 grams) and there seams to be no epproclable accumu
lation of fluorlae la any one of the vital organs. The fluorine content of
teeth and bones Is higher* being of the order of 0*01 to 0*0356, which probably
ories with the mount of fluorine l^jfhe daily diet* The symptoms of fluorine
poisoning are renewed aad aa attsegt^jp made to estimate the minimum lethal Ingestion) Hot much ar^Jtion Is given to the lahalatlon of com;
of 1
481 C9301CC Holler.
TEE R02S2fTG2NQL0GXGAL January 1939)* (British
Chronic fi estlgatlag
discovered in 1931 whga\&i^dthor was inrs and came upon euffiy^agos la the
boaee off, % t
factory*
hmcxroen recognized la
Lae that the symptoms la
iTfhe
cter and included lack of
t&k, nausea thfr^open air. I
uwsn the ladMdu&l went Into
S apparent toloreace to the
dusts following eoatl
ipol sign of fluorlae poisoning
Is la bone changes, e
bones. la the affected individ-
uals, there was almost
of noxmal body structure, the
bones of the vertebrae
it a milky white opacity* la the
extremities, the
ouch thickened and the marrow car
Ities narrowed,
ted after 2 1/2 years of exposure;
more extensive
ears* Another feature of the
condition cone
teeth* Thesa^tha
inscribed as mottled teeth, have
been rec
ly all countries.
Stated that because the occur-
ranee of^ll&J&nSf Is so extensive York^efSjs^rytflite, phosphorite aad c
1 real dust problem. should, la particular, be
extreme caution. It is impo:
agists recognize tho la
of fluorlae poisoalag, aad cert
sts are given in the
INDUSTRIAL CHLORINE GAS POISONING.
^ ergiftsf., 10, 1-2
(January 1939)* (Genoa).
'xxL
A worker la a wall chamical plant was exposed to
ns gas during the course
of an experiment. Although he had broathed only a
uat of the gas, he
had to be helped from the room and then lost consdo
At the hospital he
developed n scute, severe bronchitis, and about 3
this seemed cured
but it agsim developed a few weeks later* The bronchitl
chronic and tho
patient was troubled with an Increasingly severe cough snd^ftepnea. Respiratory
functions were badly disturbed; vital capacity was only lOOCPec* aad respiratory
misate volme was almost double the noxsal* The case is unusual In that non-
fatal cases usually do not lead to this chronic condition*
483 0NX0H CONFERENCE ON L2AD POISONING* Labor Standards, 2, 58-0. (April-Hay 1939). The control of lead poisoning was discussed by the Battery Cowell of the United Electrical, Radio and Machine Yorkers of America at a meeting In Phila delphia on March 19* Aa outcome of the meeting was the appolamunt of standing caMlttees to gather detailed lnfoxmatlon and to conduct further conferences on the subject of occupational diseases*
Reftrances to Rsceat Literature - 12
484
i
THE EARLY DIAGNOSIS 07 ACUTE AND LATDTC PLOdSI. F.L. Stlth, 2al, T# I.
Ratiwell and 0* S. Maxell* Am* 7. Clio. Path*, 8, 471-508TI938). Reprints
obtainable frcm the aaolor author, Jefferson Medical College Hospital, Philadel
phia, Pa.
The many synptcas that may be found , in laad poisoning aro listed and mention is
Bade of the diffaranea in susceptibility to lead. The authors review figures
gives as normal laad is urine and concentrations in urine of exposed and poisoned
parsons* In discussing the significant# of stippled cells, the authors list six
teen dher pathological coaditionsJLJ^flUch these colls hare been reported* In
the^JCatbor* s aeries and experlAea^Q^fTCppllag did not precede symptoas and
the tost $eg^'' Reticulocyte response and basophil!*
Ldered
te as disgnostlo tests. Detailed bloc
fcnts grouped according to clinical
diffarentlal diagnosis can bo B&de<S2A7&ate
, colls sad fibrin fraction when CHwttfired in re-
alue. Thoir analytic method is 4Arg*xn normal sub-
daily changes, had no
t'^MWtole blood values,
exercise* It is
cant that, in nozaal
in the aorta, b
s of pluBbla, serun
In chronic poisoning,
values are higher than
laad will reappear in the
485 THE CLINICAL SZOH7ICAHCS
Am* 1st* Med., 12, 1429
The naan maber of stlp;
red cells; in 234 petA*cb^ith
Billion. Five p^an) to when
after syapto&s sfttfmrsSf but 2250 up tq
exposed to l^mw|prxree of syaptoss
tration
fasmatin to 2 pati
5250 arttNM3. These data suggest that
diAdci&*? either lead absorption or 1
IN THI BBTHROCOT.E.B. Falconer.
5 normal adults was 92 per Billion cal conditions, it was 363 per .stared, had 19,950 par Billion toss appeared* In 8 workers .cell count was 2100. Adminiastlppled cell counts of a is not a specific ia-
KBaZKERATIOH IN fiHBDGNTAL LEAD FOISdiafcPBr
SOLUBLE LITER PAC-
M* Lauro, 0* S* deSacy and A* Arthus* C^t^reaft^jjac* et biol., 130,
6- 4--2---4 (1939). (Trench)*.
-.vr-_
A brief report of experiments on 55 rabbits given sx#lff<rorent liver extracts
after anemia induced by lead* Regeneration of blood^agpn within 3 to 8 days
after Istravaaous injection of the extract end reeche&^yfairly high but sub
normal level. Control animals given oo extract recoverSB^ly slightly. Regen
eration took place regardlees of aalaol'a age, duration o^^mtsent, aaount of lead injected, gravity of casBia and tine of liver injection^)
487 INFLUENCE 07 ACID AND AIZAL1NE DIETS ON PORPHYRINURIA IN KPERBCHNTAL LEAD POISQNXN3. A* Capellini* Med* del Lavoro, 30, 33-43, (1939). (Italian). Three rabbits on on add diet and threa on an alkaline ona were given 30 cc* of # solution of lead acetate daily for 30 days* Porphyrins in a 24 hr* urine sample of the asiaals on an alkalins diet was 90, 53 and 108 aiorograna. Tbs corresponding figures for the animals on add diets ware 187, 136 and 152, but la these latter, the. porphyrinuria dropped aore quickly when the lead was dis continued.
References to Recent Literature - 13
488 LEAD POISOKDO, LEAD COKEHT 0? BLOOD AND OP EXCRETA* S. L* Tcmpsett and A. B.
Anderson. Lancet, pp. 559-62 (March 11, 1939). (British).
'
'F- The lead content of blood and excreta of 29 cases of suspected lead poisoning ms deteiBiaed by the sodium diethyldlthiocarbo&ate method, certain Improvements
in which are stated in detail* The investigation confined the opinion that the
estimation of blood-lead is more satisfactory than the detetsaination of the ex
cretion of lead* The upper limit of normality for blood lead is pl&cod as 100
microgreas of lead per 100 ml* When this limit is exceeded, or if there is a
total daily excretion of 1 ng. or moatfof lead, than lead poisoning is present*
Details are given of a large asBtaaT&^tazttinatlons made. The conccntratioi
of JU4 i& the blood of tbeae cdaerfraaT ten to twenty times that in the urij
Nevertheless, iVcaanot yem clamed that the chemical diagnosis of 1<
soning^0iBfaii|j^e, e^a t^^igb it is surer than clinical methods.
489 Altar
C* Mahr* Mlkrochw., 26.
1939). (<
Lead can bex
presence of other heavy
fozsation of
very ins<
icific lead thiourea niti
the lead-containing
solutj
kc a<
'10 volume of solid
is added* After dl-.
coo, foSmition oi
itals Is observed
microscope. The lead
nitrate pr^etbital
doubly
iedlelike prims, 20-50 mi-
__ long and very
Let asf^rtS)?crossed and frequently united in
star-shaped bundles*
lead earn be detected in the pre-
sence of 60-70 parte b:
more than 100'of cadmium, arsenic.
tin. silver, platinum
The metals of the menoaiia sulfide end
alkaline earth groups do
similar concentrations. The spocifl-
city may be increased ab<
Lous separation of the lead as
lead oxide on the plat: "
Lting concentration of lead is
about 1:40,000*
490 PAD7TDC PR
C. D* Bridges. 'S^ety^S&g^TT, 44-7, (May 1939).
Thera
Rdfc?ferent types of pa^gU^eiitt^ffixfactured by mamrous firms,
and 'ingredients are used thatxCy^imroSfcle to determine the toxicity
:s. The safest practice is Yif mlnjf^TTmer 11rtnni possible when
type of paint or lacquer. Whe^QWing(M)Bta, exhaust booths are
>le where it la possible to ploy thdeicyiption is given of the
ratal principals of exhaust booth construction*
exhaust ventilation
la not applicable, respirators should be worn.Tbgy sSwd be supplied air res
pirators, as this type is more efficient sad morejcomfortable for continued wear,
and the air supply is convenient. The air Una
be passed through a filter
to remove fuses, dust, moisture, etc. It should be<^M^bertd that dust respir
ators do not protect against fines. Paint daimatoseS^d^e to allergy to the var
ied Ingredients, may be controlled by protective cloth^g^aad the use of pro
tective skis Tim such as vasoline end cold crew, aal-raarentlng tbs use of
solvents for washing. Paint brushing involves expeeure^o jizft solvents and re
quires, primarily, good ventilation.
^
491 MEDICOLEGAL COMPLICATIONS IN DEBCAT0L0GY CAUSED BY MASSAC3JSEXTS WOBDCN'S CCMPStSATIOH ACT. J.S. Slaisdell. Arch. Dermatol. 3b Syphilol., 39. 69-80 (January 1939).
The author shows that the question of compensation is largely dependent on the interpretation which, since the enactment of the compensation act, has become evolved through practical experience. Be stresses the difficulties that arise for the dezsatologlst in testifying before a group of lay referees becauso :f the impossibility of always giving a definite Tee* or "No* answer. Es gives
consideration to the use of patch tests in evidence before the referees. Follow ing these discussions are several suggestions for changes in the present law.
References to Recent Literature - 14
492 COEAHBHB BSSTZ0I8 AMOBQ XSDG9XSXAL 101BSS. J. 0. Donning. Area. Daunt, Syphilol. 39, 12-92 (January 1939).
The author presents a large bus of important data relative to industrial dexsa-
toaaa, taken frcm a study of 2000 eases. Ee baa aany tables which bear careful
study by those interested la the subject. Prevention and diagnosis of dexaato-
sis eases are auch cheaper than neglect. A process should not he condemned as
dangerous because one or a few workers are peculiarly sensitive. The largest
saber of coses occurred in young untrained workers between the ages of 20 and
25 and the hands were the nest frcquanj&r involved area of the body. There is an interesting discussion of the distreMution of dexaatosos according to ocsupc-
tions./WBd there ore excellent si^Qrise^of important contacts, oatorials us<
and Wnayhcteriiti^ affacts in-tba ds4rierent occupations. In discussing
tion taaea
Upo]
>f detocting and ellnl natiag hazards, importence of gloves, and protoctiv
and little value in prs rnnploymant pet
cusses
proper evaluation of the teats as
tlonal
493 DOS TO PHDTOSJKSITtS&ATIOir. H. R. Toerstr
and ts^atti&tz. n^dh.
> Syphilol., 29
uary 1999).
TTnffll
'actorlea uai
tar produets. Most of
thd^pxtansous laalo:
found
s who handled pitch or pitch
proouots and who
Patch testa wore perfoxmed on
14 pitch workers and 4
;ha different fractions of the
pitch and tar, and the
exposed to radiation of various
wavelengths. Sane of the
chMicai and physical properties of the
pitch are discussed in del
studies, the authors conclude that
pitch desaatltls end
She its of true photosensitization and
not of allergic sens
_
This photoaansitlzation occurs
through local exoMnftriJhctlvlty
tosensltlzer. The tests re
vealod that no. praYftgar fraction of "the pi
distillate of the tar can be
hold respoufSgejpf the production o^^fiot
cation. The most important
radlatign^B^prt in the range of blue- ^
visible light and in the
long^am&wdgths of ultraviolet light (
real) The aost active
casclsomouic hydrocarbon in pitch, namely
, which has fluorwscent
2900 and 3800 Angstroms, is prob
the photosensitizing
Lents.
OIL BBNAXms. Anonymous. Safety Sag., 77, 49-SQ.(1ley^939).
The article reports on seme researches carried otfTC&dazmatltls from cutting
oils, about which the following ooncluslons are dramj>The oil itself is cot
the direst cause of the sttn irritation; rather it is\^he^du*t and bacteria for
which the oil fosms a suitable vehicle. The bacteria a^ri^t from the oil, but
are on the sttn; all cutting oils are capable of penatrntSflJihs akin surfaces
and the bacteria eater by this Boons. These bacteria olso^fxai^ entry to the
sldA through minute, cuts made by metallic particles in *uspd|(on in ths oils.
Prevention is best accomplished by thorough cleanliness. The affected ports
should b# washed twice a day in soap and water end no oils or gasoline should be
used to rwove dirt.
496 AIXALX 2CZBCA, ITS tSTOOBCSir AND PRETBfliaS, HTH SPECIAL RZTZRZSCS TO M0D2EK 9QAPS (PBACDEAV, SATZHA}. H.f.Schreus. Med. Welt., 13, 222-9, (1989). (Gexman). The author considers that usually in hypersensitivity to alkalies, no reel sliergle hypersensitivity is present, but as iomediate sensitivity brought on by chAleal sad pfayslco-chMieal reactions, only prolonged contacts are invariably effective. Since ****** icimii are only exacerbated by alkaline soaps, special alkali-free soaps such as *Pracutan* are recemnended.
References to Secant Literature - 15
496 CHRONIC GRANULOMA IH IHDCSTRIAL BB9CAI010GT. H. X* Miller. Arch. Dezmat. ft
Syphllol., 39. 33-44 (Xanuazy 1939)*
la 3000 petienta examined for the industrial responsibility of their nation
the author fotmft 26 with chronic granulomate of which 16 war* syphilis, 9 wore
cutaneous tuberculosis, 1 blastomycosis, 1 actinomycosis, and 3 war* leprosy,
the role whieh each plays in these cases is discussed briefly* When chancres
develop in the sites of Industrial injuries, the carrier of insurance mist pro-
wide treatment. She localization of lesions of secondary syphilis is rarely in
fluenced by truss, but the lesions of late and latant syphilis asy often local
ize on the sites of injury end will therefore be important la the evaluation of
Industrial dezmatoses. Miller warosSfaraiciaaa diagnosing
treating Indus-
triaXvdaxmatosee to be on the 1tuberculous chancres since be belli
ttt^ljipldsnee will rise inJh& fwf^m due to the definite decrease in earl]
moi '
TEX IHDCSTKIAL GBCASOSES.
1939).
records will provide a means fo&gitt&Eftng the inci-
.dezsatoses and relate such isdleesfliiroceupetlons or
.oyment examl nations
mattr to afford an oppor-
to reaction type atie'fW*'* the physician to ad-
author discusua\mip<or the important practical
rkera whn<wSt'4aely to be exposed to dexeato-
498 smmns nm Med. Assoc., 112, 2132 Nicotinic acid has been
from ita specific eff< sensation of
ministration.
that nicotlal persons
_
capable of Stn nicotinic aci^t
all of the 4 cases
of a slid sunburn cases the condition subs! of the workers experienced these
COTZHIC ACTS.
M. Watrous. X. Ax.
comparatively inert substance aside Patients have, however, noticed a following oral or intravenous adstories are presented which indicate ent dermatitis in certain the course of their nanufacaffected ports of the skin and itching sensation, tvo. Only a small pro-
ASEFTIC NBCRPSI3 OP BOMB. I. INFARCTION OP
BZSSASX KE5QLTZ2K
ZH SCAPSULASXD AS) CALCIFIED ARIAS XS
DXTOWANS.
S. C lahlstrom, C. C. Burton, and D. B. ?bed ^Surg., Qyn. ftObst., 68.
1u2s9w--4e6o (yFseboruary 1ix9a3s9i).
Caisson disease (oppressed air disease) is the reinlt=of tissue injury caused
by nitrogen which cornea out of solution in the blood^aifchody fluids in the f01*
of bubbles following too rapid decompression after expires to increeaed pressure
Because of the greater solubility of nitrogen In fata, ti^Ltissuea with a high
fat content are sites of predileetion for bubble foxsstloS^)The tendency for
bubble fozmation to occur in the spinal cord, the asms, sd the subcutaneous
tissue la thus explained and bee often been described. Sowwver, with the ex
ception of a single ease, reported in 1888, thne la no report on the patholog
ical findings in the bones and joints in caisson disease. The present paper
describee 4 cases of compressed air illness In which extensive bone end Joint
changes are found. The cases are
well presented, with complete case
histories, x-ray and autopsy material, and illustrations. Zt is not improbable
that as a result of the findings, bone and joint changes attributable to this
disease will come to be regarded as a ecmpensable occupational disease, and acre
attention will be paid to the prevention and early treatment of the condition.
References to Hsceat Literature - 16
900 CCMFRESSBJAEH DISEASE IK BUILDING THE BEECH ACTIO HOAD "HAmBHOCKMIEDEl" AT TBB 3BVSBBB TAHBWT 07 TBS BBg.TK RING. R. Eoaig. Munch. mad. Echnschr., 86. 370-3 (1999)* (German).
Tii# author. At permanent medical supervisor of the cooprossed air work which reached a depth of 30 satart water gage, was always present during construction. Ha praaants thraa lstsraetlag case histories and goaaral data oa tha symptoms obaarrad. It is of interest that in reca&praasion, improvement took piece at 2 to 3 saters water gaga.
901
MEDIA: ITS AILE7IATI0K
OK Bf TBB IKHALATIOH 07 3ELXCM
V* B* Lovelace, C. W.
K. Boothby*. Proc. Staff Maatiags
c, 14,
(7a
*w)
a complaint of alrplaaa pilots cad ia descent in flight. This is duo
a which causes it to toad to nsal&^dllte'Sd' unless
efforts or other measures
opaa it
sa of equalizing pressure in thjraijPSe ear. It has that heliia-ojygsn niztoss pwttnt or greatly dl-
auggastad that, InL^fiHupnes equipped with in-
especially^
aiztures be inMnSB nnac narked ohaagas ia
902 IBDmjJUAL PARIAHO
TO HIGH ALTITUDE. A. Bays, B.H.
W. Matthews, V. 8. Torbeg/
Proc. Boy. Soc., 126. Series B
1-24 (Septmtter 1938). {
Individuals differ nark'
ty to adjust to the rarefied air of
high altitude, and this
related to a nutter of neasurable
characteristics at sea-
aozmal nan between the ages of 29
sad 44, habituated
t youth, alow pulse, lew-normal
blood o^rgen caMeffe^^bw alveol -omen o^de prassurn^^pgh alkaline resarf^> at natizatlo^tfi&rnltltuda. It is
, high alToolar-carbon di al are favorable for accll^ careful cbeervatloa over a
nmbarjaMnr=fly trained observers gt
*.bet$e&4ndieatlon as to relative
per$g^^o^br acellnatizatlon than any
a yet devised.
COK TO TBB MBCHAHIfM 07 ASAPCA2&
ac TO BEOB T2KPERA-
^ S. P. Sharovatova. Bull. Biol, at "(Hussian)
u
6, 671-4, (1938).
Single or repetitive exposure of dogs to heat (
gastric secretion
in response to a particular food stisulus, and
the orguiic components
of the Juioe; the iaorganio components zmained prao
unchanged. The ob-
served oheagea indicate the participation of both ths^nedpe-reflex and neuro-
cheuical regulating syvtss.
^X^>
O)
504 HEAT 9E80D i ATJ.TP COKBrnOKS. T. B. Kichnlls. X. ^gpy Mad. Corp,
72. 73-64 (Pebruary 1939). (British)
\s>
A review of the subject, written especially for easy nan in the tropics, The
use of salt in the author** group reduced heat stroke to zero.
909 QBSnrmOB OK TSX BLOOD 07 10SKBI EXPOSED TO BEflB TMFBAIUBB. P.L. McLain cad B.3. Montgomery. J. Clin. Invest., 17, 417-22 (1938). Observations on a control group of 43 workers in hot industries and 30 patients admitted to a hospital for boat symptoms. In the latter group there were 17 cases of heat crwpe, 4 of beat exhaustion and 7 of beat retention (stroke") Careful blood tests were made; in the controls there was dalydratlon and fall of blood sugar folioeing work; in tha patients, tha changes depended on the type of heat alliant involved.
References to Recant Literature - 17
506 fiEASQB AKD VSKCXUTBtt STSTBCS FOR FHTSICAL COMFORT. A. Bindley. J. Xaat. Beat. ATant* Xogrs. London., 7, 36-42 (lurch 1939). (British). In this short paper tbs author give* aouxid and interesting discussion of beat ing tad ventilating systems in relation to husan comfort. St regards as tho main essentlals-ifor sedentary workers in Grant Britain), a tsperature of 64 to 68?.a moderate relative frigidity, clean air, and adequate air movement; ha later refers to the desirability of variable air currents rather than a uniform and monotonous rate of movement. The>author concludes that, in Great Britain, except for certain industrial purposi air conditioning is overrated, and that
the sir washer and refrigeratordispensed with, substituting for vet lotifflg purposes only a largegvoiVjp' of fresh air art making provision fo;
air merchant to bjKHW ** required,
507 FHDTB* Deeembi Over 7600" during 193j aant for/
prev< viaora(
various operations appliances are glv<
Borne Office, factory Departme,
sware reported to the factory
Groat Britain
tents reported are probably
causing disable-
k total number of eye aci
.ts'Tb not loown but this
>rhood of 100,1
The leaflet deals with
.dents.
ad portable), hairnets,
to, and the requirements for
inti*
the maintenance of protective
SOS CHDCICAL MCSCLE CHARGE' mod., 17, 76-86 (1939). In eniaals experiment finds deminaralinatlj alia, and potaasj after tho end
to eleei
'C TBAIMA. G. Montsmartlni. folia
ted with an alaetrlo current, the author and alteration in calcium, aagne-
iun to normal, however, some time
8T ,
G. Allsop and R. 7.
Iastn. Min. Bngrs. Len4r*\ 96;
(fabruory 1939). (British),
;s hare clearly aatablishad
mixtures can easily ba
by tha rubbing of blunt pick , ek-^B^against pyrites, and it
>ught that tha mechanism of tha ignii
u Uhdsr tha rubbing
ttion, soma of the pyrite is redu
haatad to between
200 and 300C. Within thia range of tspers'
t&t^on of the powdered
pyrite procseds rapidly and ultimately fls (b
sulfur) appears. This
flame ignites the firedamp
510 DOCDMffltS Of OCCBFJOZQKAL ANTHRAX. Med. du travail, * 48-66 (1939). (french),
French rules regarding compensation of anthrax as an its former compensation as an accident, are reproduced
tional disease and )( soussed. Instruc-
tiona for tha prevention of tha disease are also InBludefl^jjne author reports
on two oases treated with serum and with fomentations of septoplix (paramino-
phenil-sulfaald). S also mentions eight other cases treated by Murteanu and
Zaltaan with other sulfamida.
511 PBOFHZ3UOXS Of MOORS' AKXLOSTOMXASXS IB IB* LOIRE TAILS. C. Gorin and 2. Roman. Ann. d'hyg. pub* ind. too., pp. 56-66 (February 1939). (french). Infranee, miners' ankylostomiasis (also called miners' anmnia or tunnel anmtia) la a ccmpanaable disease. Zt can be prevented by keeping the nines as free as possible of worm larvae and by axninlng and treating the workers. An intensive
References to Recent Literature 18
effort nu made la two state ployiag 4900 sen* The percentage of infested qen, varying widely Ow pit to pit, was found to react from I9fi to 6SJt. of th* la* fostod workers treated with tetrachlorethylene( 89$ were entirely freed of pare* sites; chenopodlum oil ead thymol were aot aore than 50 effective end quinacrine was useless* final examination showed the infestation to hare dropped markedly in all groups although it had not been completely- wiped out*
512 WEIL'S DISEASE IB COAL MEHKSS* * S* IS* arlt* Med. J., pp. 603-3 (March 25.
1939)* II* CLOBCAL PAX3DL0GT*
en* Ibid* pp* 605*7* (British)*
The prevalence of Veil's disease aaoni^S3kth Vales
shown by the sis cases reported toms were typical; jaundice, &ej
and uscular pains* One of the cases was fgj
diagnosis
base by serological investigation and di
agglutin*
'eptosplra* Laboratory iBvestigatlons<g$i\e^ out in
tables
blood ezaminatlOBS, blood counts, flmlnfiexBBlnations,
tests :
Vassesmann reactions, animal .l^nlmfton experl-
meats t
and the presence of urine wroln, urobilinogen
and worked together and enwrxla in wet places in-
feet c
taken to rid thfwVfir of rats, as no further
513 SPIROCHETAL JABHDICX
OP A 7AEAL CASS IH A IXSS
MBCBAMT* M* V, Uton.'
_ 219-23 (March 1939)*
This is said to be the eii
from Veil9# disease (see Abstract
433, 1939) in this eemtry*
described along with vary careful
laboratory tests* Urine
.tient's admittance to the hospital
was injected into a
jaundice on the 12th day and died
within 24 hrs* On ;
to be swarming with typical
leptospirae, wldcttNM^ spread
liver and vara abundant in the
/tuoular opithpl^Sw^Xjtocond guinea pig,
ted with the urine of the
first, also (Sai&^Klaroseoplcally n^jpLso
were visible in tho patient's
urine
thsrguinea pics' blood or
*UESCOCr SCBCPTXBniTT 07
ntoxxQK ntro&r* carl
and P* V* Zlamszmsn* Contrib.
Institute* 10, 135-
(Januory-March 1939)*
From a review of the literature and new experagptal
knowledge of the
action of sulphur dio^Ae on plants has been increased*
of the conclusions
made are as fallows: (1) plants are more resisted
phur dioxide at tm*
peratures below 40F*;. (21 resistance generally
with an increase in
tbe relative hattdity, (3) plants grown with an
of water are aore
susceptible than those with an Inadequate supply, (4)
grown in poor soil
are aore susceptible than plants In good soil, (3)
in light intensity
(as a heavy shade) below 39% decreases the resistance,
young plants are
aore resistant than older oaea* A second paper on the
is to follow at
a later date*