Document rewkqMKKVpOmd3jG8p5K457O0

TO: Carl Kerfoot-Ponca City Interoffice Communication FROM: DATE: SUBJ: T. G. Grumbles September 21, 1988 COMPARATIVE SKIN IRRITATION TESTING VISTA The current price of a dermal irritation study is $350-400. If we plan to do a comparative study we need to carefully consider the design of the study. The inherent variability of acute toxicity studies could lead to erroneous conclusions if we aren't careful in our design and analysis. Let me know when you want to discuss further. T. G. Grumbles dlj