Document re8rp0MZKrgpj5Nzjm3627NEe

TO: Interoffice Communication FROM: DATE: SUBJ: Dave Penney-Austin XF: ^ 7 I ' RF T. G. Grumbles November 7, 1990 VIST/ OECD HIGH PRODUCTION VOLUME EXISTING CHEMICALS PRODUCTION PROGRAM Attached is a CMA request for Vista to participate in the subject program for tetradecanol (ALFQL 14). P&G and Ethyl are the other producers in the U. S. that have been asked. We've responded (see attachment) to Option C, to form a consortium. I'll keep you posted and get you involved when the time is right. T. G. Grumbles dlj Attachment 000028357 CHm CHEMICAL MANUFACTURERS ASSOCIATION OCT 1 0 I99u >v\ Robert A. Roland President October 3, 1990 John D. Burns President and CEO Vista Chemical Company 900 Threadneedle Houston, TX 77079 Dear John: We are asking for your participation in the Organization for Economic Cooperation and Development (OECD) High Production Volume (HPV>- Existing Chemicals Testing Program. We are requesting that you indicate yoor commitment to take lead responsibility for a chemical in the OECD Chemicals Program by completing the enclosed reply form. The OECD Chemicals Program offers the most viable forum for harmonizing international testing requirements and acceptance of test data. The OECD program will also promote sharing the burden of chemical testing with producers in other countries. Additionally, the OECD program could influence the EPA*s efforts to "revitalize" the TSCA testing program and the European Economic Community's proposed regulations. The OECD HPV Chemicals Program was endorsed by CMA's Board of Directors .in September 1989, and several U.S. producers agreed to participate, in Phase I of the Pilot Program. The Pilot Program is a voluntary effort to systematically investigate the potential human health and environmental effects of HPV chemicals (see Attachment I). Initial work on the HPV Chemicals Program invoLves collecting available data and undertaking testing necessary to complete a screening information data set (RIDS), CMA's Board of Directors recently approved recommendations for CMA member involvement in Phase II of the OECD HPV Chemicals Program and discussions are beginning within the U.S. and OECD regarding allocation of Pilot Program Phase II chemicals (see Attachment II). Your company has bean identified from publicly available records as producing one or more of the HPV chemicals to be evaluated in Phase 11. We are seeking commitments from individual companies in anticipation of a January 1991 OECD Ministerial meeting. At that time, producers taking lead responsibility for Phase II chemicals will be formally identified. The number of CMA member companies making commitments to take lead responsibility for Phase II chemicals will be reported to the Board at its November 1990 meeting. VVV 000028358 2501 M Street, NW, Washington. DC 20037 202-887-1106 Telex 89617 (CMA WSH) Mr. John D. Burns October 3, 1990 Page 2 If you have any questions about the OECD HPV Existing Chemicals Testing Program, please call Kathryn A. Rosica, Director, Health Programs, at 202/887-1282 or Sandra L. Tirey, Associate Director, Health Programs, at 202/887-1274. President cc: Mr. Thomas G. Grumbles, Health and Safety Contact Mr. William McClain, International Contact VVV 000028359 ATTACHMENT I OVERVIEW OF THE OECD HIGH PRODUCTION VOLUME (HPV) EXISTING CHEMICALS TESTING PROGRAM The Organization for Economic Cooperation and Development (OECD), an organization of 24 industrialized countries, has initiated a voluntary program to systematically investigate the potential human health and environmental effects of high production volume (HPV) chemicals, A Screening Information Data Set (SIDS) has been developed for an initial evaluation of the potential hazards of these chemicals. In Phase I of the Pilot Program, 53 HPV chemicals were chosen from a list of 147 HPV Priority 1 chemicals that are produced in excess of 10,000 tons per year by any OECD country and for which little or no safety data are publicly available. In Phase I, fourteen (14) OECD member countries, Including the U.S., agreed to 1) take the lead on specific chemicals; 2) exchange existing data on these chemicals; and 3) conduct testing needed to complete the SIDS for each chemical. Total testing costs per chemical will depend on the extent of existing data and could cost up to $200,000. U.S. chemical producers have volunteered to take the-Iead on nine of the 53 Phase I HPV chemicals. One company is taking the lead on two chemicals, five companies are taking the lead on one chemical each, and the Silicones Health Council is taking the lead on two chemicals. U.S. chemical producers and EPA have also provided existing data on the Phase I HPV chemicals to the appropriate national SIDS contacts or U.S. producers. The U.S. chemical dossiers, including available data and proposed testing plans, were reviewed in September at a meeting hosted by the Conservation Foundation. This meeting included representatives from federal government agencies, environmental groups, academia, and industry. The purpose of the meeting was to develop consensus views for the U.S. delegation to carry forward in subsequent OECD meetings. OECD member countries will meet in November 1990 to review the 53 HPV chemical dossiers and proposed SIDS testing plans. This meeting will provide an important opportunity to judge the viability of the OECD program. The ability of participating countries to reach consensus on evaluating existing data and proposals for testing is key to continued participation of both OECD countries and individual chemical producers. SIDS testing on the 53 pilot phase HPV chemicals is expected to begin in December 1990, with testing completed by December 1991. Phase II of the OECD HPV Existing Chemicals Testing Program is expected to begin in early 1991 with formal allocation of the remaining HPV Priority 1 chemicals to OECD countries. Collection and sharing of existing data is to be completed by August 1991. Review of existing data and SIDS testing proposals is scheduled for December 1991, and SIDS testing is to begin in April 1992. Wv 0028360 ATTACHMENT II OECD HIGH PRODUCTION VOLUME PRIORITY 1 CHEMICALS PHASE II CANDIDATES Alcohols *2-Methyl-3-buten-2-ol (115184) 2-Methyl-3-butyn-2-ol (115195) *l-Tetradecanol (112721) *l-Tridecanol (112709) Aldehydes and Ketones 2- Ethyl-2-hexenal (645625) 3- Hydroxy-2,2-dimethylpropanal (597319) *3-Nitrobenzaldehyde (99616) Pentanal (110623) 2,6-Dimethyl-4-heptanone (108838) Ethenone (463514) Amides and Sulfonamides N ,N-Bis ( 2-hydroxyethy 1) -9-octadecenami.de (93834) *Diazenedic.arboxamide (123773) *N ,N 1 - 1,2-F.thanediy lbisoctadecenamide (110305) (Hydroxymethyl)urea (1000824) *3-0xo-N-phenyIbutanamide (102012) Amines and Nitro Compounds N,N'-Bis(3-pheny1-2-propenylidene)- 1,6-hexanediamine (140738) 5-Amino-1,3,3-trimethylcyclohexanemethylamine (2855132) N-Methy1-N-octadecyl-1-octadecanamine (4088226) 1- Tetradecanamine (2016424) *N-Pheny1-1,4-benzenediamine (101542) 2- Methyla 1ly1 2-nitrophenyl ether (13414545) VVV 000028361 ^Manufactured by CMA member companies not participating in the first phase of the pilot program. 2- - A Carboxylic Anhydrides, Acids, Esters and Salts Butanoic acid anhydride (106310) Benzene-1,2,4-tricarboxylic acid (528449) Diethyl 2-butenedioc acid (E) (623916) 2.2- Dimethylpropanoic acid (75989) 3-Nitrobenzoic acid (121926) 3-Hydroxy-4-[(4-methy1-2-su1fophenyl)azo]-2-naphthalenecarboxylie acid, calcium salt (5281049) Decyl 9-octadecenoate (Z) (3687465) 2.2- Dimethyl-l-(l-methylethyl)-l,3-propanediy1 2-methylpropanoate (6846500) 3-Hydroxy-2,2-dimethylpropyl 3-hydroxy-2,2-dimethylpropanoate (1115204) *Methyl dodecanoate (111820) Methyl octanoate (111115) Methyl 3-oxo-2-pentyl cyclopentaneacetate (24851987) Methylene butandioate (97654) Octyl octadecanoate (109364) Chlorinated and Fluorinated Compounds *l-Chlorobutane (109693) 1-Chlorooctane (111853) 1.3- Dichloro-2-propanol (96231) *1 -Chloro-4-(trifluoromethy1)benzene (98566) *1,3-Dichloro-2-methylbenzene (118694) *2,4-Dichloro-1-methylbenzene (95738) Diols and Glycol Ethers *1,6-Hexanediol (2629118) *2-l2-(2-ethoxyethoxy)ethoxy]ethanol (112505) ((1-Methy1-1,2-ethanediy1)bis(oxy)bispropanol (24800440) Methoxymethanol (4461523) Heterocyclics 2-(1,3-Dihydro-3-oxo-2H)-3H-indol-3-one (sic) (482893) 4,5-Dihydroxy-1,3-bis-2-imidazolidinone (sic) (1854268) *5-Ethy1-2-methyIpyridine ( 104905) VVV 000028362 Manufactured by CMA member companies not participating in the first phase of the pilot program. -3- Hydrocarbons, Aliphatic *Decane (124185) Dodecane (112403) Pinane (473552) Tetradecane (629594) *Tridecane (629505) *Undecane (1120214) *1-Butene (106989) 1,3-Cyclopentadiene (542927) 6,6-Dimethy1-2-methylene(lS)bicyclo[3.1.1]heptane (172673) *l-Dodecene (112414) *1-Hexene (592416) *2-Methyl-2-butene (513359) 2-Methyl-1-propene (115117) *l-0ctene (111660) *1-Tetradecene (1120367) Hydrocarbons, Aromatic *1,4-Diethylbenzene (105055) 1-Phenyldodecane (123013) 1-Phenyltridecane (123024) 1- Phenylundecane (6742547) Nitriles 2- Hydroxypropanenitrile (78977) 2- Pentenenitrile (26294964) 3- Pentenenitrile (4635874) Organometal1ics Decanol aluminum salt (26303548) Dodecanol aluminum salt (14624158) Octanol aluminum salt (14624136) Tetradecanol aluminum salt (67905322) Tridodecyl aluminum (1529595) Tris(decyl) aluminum (1726665) [[N,N'- 1,2-EthanediyIbis[N-(carboxymethyl)glycinato]J(4-)-N,N r,0,0* ferrate(l-) (21265509) Tetrakis[tris(methylpheny1)phosphite-P] nickel (T-4) (35884663) VVv 000028363 ^Manufactured by CMA member companies not participating in the first phase of the pilot program. * -4- Peroxldes Bis(1-methyl-1-phenylethyl) peroxide (80443) Phenylenebis(1-methylethylide) peroxide (25155253) 1-Phenylethyl hydroperoxide (3071327) Pinanyl hydroperoxide (28324529) Phenols 3-Methyl-4-nitrophenol (2581342) *4-0ctylphenol (1806264) 2,4,6-Trimethylphenol (527606) Phosphorous and Sulfur Acids, Esters and Salts Dibutyl phosphate (107664) Methylphenyl diphenyl phosphate (26444495) Diethyl phosphonate (762049) *Tris-(l-chloro-2-propyl) phosphate (13674845) *0,0-Diethyl phosphorochlorodithioate (2524041) 0,0-Diisoocty1 phosphorodithioate, zinc salt (28629665) *0,0-Dimethyl phosphoramidothioate (17321470) *0,0-Dimethyl phosphorochlorodithioate (2524030) 0-(1-Methylethy1) carbonodithioate (140932) Ethenesulfonic acid, sodium salt (3039836) 2,2f-(l,2-Ethenediyl)bis-(5-amino)benzenesulfonic acid (81118) VVV 000028364 Manufactured by CMA member companies not participating in the first phase of the pilot program. IZ& CHEMICAL MANUFACTURERS ASSOCIATION Qe-^7,/ Robert A. Roland Presidem October 3, 1990 John D. Burns President and CEO Vista Chemical Company 900 Threadneedie Houston, TX 77079 Dear John: We are asking for your participation in the Organization for Economic Cooperation and Development (OECD) High Production Volume (HPV) Existing Chemicals Testing Program. We are requesting that you indicate your . commitment to take lead responsibility for a chemical in the OECD Chemicals Program by completing the enclosed reply form. The OECD Chemicals Program offers the most viable forum for harmonizing international testing requirements and acceptance of test data. The OECD program will also promote sharing the burden of chemical testing with producers in other countries. Additionally, the OECD program could influence the EPA's efforts to "revitalize" the TSCA testing program and the European Economic Communityrs proposed regulations. The OECD HPV Chemicals Program was endorsed by CMA's Board of Directors in September 1989, and several U.S. producers agreed to participate in Phase I of the Pilot Program. The Pilot Program is a voluntary effort to systematically investigate the potential human health and environmental effects of HPV chemicals (see Attachment I), Initial work on the HPV Chemicals Program involves collecting available data and undertaking testing necessary to complete a screening information data set (SIDS). CMA's Board of Directors recently approved recommendations for CMA member involvement in Phase II of the OECD HPV Chemicals Program and discussions are beginning within the U.S. and OECD regarding allocation of Pilot Program Phase II chemicals (see Attachment II). Your company has been identified from publicly available records as producing one or more of the HPV chemicals to be evaluated in Phase II. We are seeking commitments from individual companies in anticipation of a January 1991 OECD Ministerial meeting. At that time, producers taking lead responsibility for Phase II chemicals will be formally identified. The number of CMA member companies making commitments to take lead responsibility for Phase II chemicals will be reported to the Board at its November 1990 meeting. vvv 000028365 2501 M Street, NW, Washmgion. DC 20037 202-887-1106 Telex 89617 (CMAWSH) Mr. John D. Burns October 3, 1990 Page 2 If you have any questions about the OECD HPV Existing Chemicals Testing Program, please call Kathryn A. Rosica, Director, Health Programs, at 202/887-1282 or Sandra L. Tirey, Associate Director, Health Programs, at 202/887-1274. President cc: Mr. Thomas G. Grumbles, Health and Safety Contact Mr. William McClain, International Contact ATTACHMENT I OVERVIEW OF THE OECD HIGH PRODUCTION VOLUME (HPV) EXISTING CHEMICALS TESTING PROGRAM The Organization for Economic Cooperation and Development (OECD), an organization of 24 industrialized countries, has initiated a voluntary program to systematically investigate the potential human health and environmental effects of high production volume (HPV) chemicals. A Screening Information Data Set (SIDS) has been developed for an initial evaluation of the potential hazards of these chemicals. In Phase I of the Pilot Program, 53 HPV chemicals were chosen from a list of 147 HPV Priority 1 chemicals that are produced in excess of 10,000 tons per year by any OECD country and for which little or no safety data are publicly available. In Phase I, fourteen (14) OECD member countries, including the U.S., agreed to 1) take the lead on specific chemicals; 2) exchange existing data on these chemicals; and 3) conduct testing needed to complete the SIDS for each chemical. Total testing.costs per chemical will depend on the extent of existing data and coaid. cost up to $200,000. U.S. chemical producers have volunteered to take the lead on nine of the 53 Phase I HPV chemicals. One company is taking the lead on two chemicals, five companies are taking the lead on one chemical each, and the Silicones Health Council is taking the lead on two chemicals. U.S. chemical producers and EPA have also provided existing data on the Phase I HPV chemicals to the appropriate national SIDS contacts or U.S. producers. The U.S. chemical dossiers, including available data and proposed testing plans, were reviewed in September at a meeting hosted by the Conservation Foundation. This meeting included representatives from federal government agencies, environmental groups, academia, and industry. The purpose of the meeting was to develop consensus views for the U.S. delegation to carry forward in subsequent OECD meetings. OECD member countries will meet in November 1990 to review the 53 HPV chemical dossiers and proposed SIDS testing plans. This meeting will provide an important opportunity to judge the viability of the OECD program. The ability of participating countries to reach consensus on evaluating existing data and proposals for testing is key to continued participation of both OECD countries and individual chemical producers. SIDS testing on the 53 pilot phase HPV chemicals is expected to begin in December 1990, with testing completed by December 1991. Phase II of the OECD HPV Existing Chemicals Testing Program is expected to begin in early 1991 with formal allocation of the remaining HPV Priority 1 chemicals to OECD countries. Collection and sharing of existing data is to be completed by August 1991. Review of existing data and SIDS testing proposals is scheduled for December 1991, and SIDS testing is to begin in April 1992. VVV 000028367 ATTACHMENT II OECD HIGH PRODUCTION VOLUME PRIORITY 1 CHEMICALS PHASE II CANDIDATES Alcohols *2-Methyl-3-buten-2-ol (115184) 2-Methyl-3-butyn-2-ol (115195) *l-Tetradecanol (112721) *l-Tridecanol (112709) Aldehydes and Ketones 2- Ethy1-2-hexenal (645625) 3- Hydroxy-2,2-dimethylpropanal (597319) *3-Nitrobenzaldehyde (99616) Pentanal (110623) 2,6-Dimethyl-4-heptanone (108838) Ethenone (463514) Aaildes and Sulfonamides N,N-Bis(2-hydroxyethyl)-9-octadecenamide (93834) Diazenedicarboxamide (123773) *N,N' -1,2-Ethanediylbisoctadecenamide (110305) (Hydroxymethyl)urea (1000824) *3-0xo-N-phenylbutanamide (102012) Amines and Nitro Compounds N,N*-Bis(3-pheny1-2-propenylidene)-1,6-hexanediamine (140738) 5-Amino-1,3,3-trimethylcyclohexanemethylamine (2855132) N-Methyl-N-octadecyl-l-octadecanamine (4088226) 1- Tetradecanamine (2016424) *N-Phenyl-1,4-benzenediamine (101542) 2- Methylally1 2-nitropheny1 ether (13414545) VWV 000028368 Manufactured by CMA member companies not participating in the first phase of the pilot program. -2- t& Carboxylic Anhydrides, Acids, Esters and Salts Butanoic acid anhydride (106310) Benzene-1,2,4-tricarboxylic acid (528449) Diethyl 2-butenedioc acid (E) (623916) 2.2- Dimethylpropanoic acid (75989) *3-Nitrobenzoic acid (121926) 3-Hydroxy-4-((4-methyl-2-sulfophenyl)azo]-2-naphthalenecarboxylie acid, calcium salt (5281049) Decyl 9-octadecenoate (Z) (3687465) 2.2- Dimethyl-l-(l-methylethyl)-l,3-propanediyl 2-methylpropanoate (6846500) 3-Hydroxy-2,2-dimethylpropy1 3-hydroxy-2,2-dimethylpropanoate (1115204) Methyl dodecanoate (111820) Methyl octanoate (111115) Methyl 3-oxo-2-pentyl cyclopentaneacetate (24851987) Methylene butandioate (97654) Octyl octadecanoate (109364) Chlorinated and Fluorinated Compounds *l-Chlorobutane (109693) *l-Chlorooctane (111853) 1.3- Dichloro-2-propanol (96231) *l-Chloro-4-(trifluoromethy1)benzene (98566) *1,3-Dichloro-2-methylbenzene (118694) *2,4-Dichloro-1-methylbenzene (95738) Diols and Glycol Ethers *1,6-Hexanediol (2629118) *2-[2-(2-ethoxyethoxy)ethoxy]ethanol (112505) ((1-Me thy 1-1,2-ethanediy l)b'is(oxy)bispropanol (24800440) Methoxymethanol (4461523) Heterocyclics 2-(1,3-Dihydro-3-oxo-2H)-3H-indol-3-one (sic) (482893) 4,5-Dihydroxy-1,3-bis-2-imidazolidinone (sic) (1854268) *5-Ethy1-2-methylpyridine (104905) VVV 000028369 Manufactured by CMA member companies not participating in the first phase of the pilot program. -3- i Hydrocarbons, Aliphatic Decane (124185) Dodecane (112403) Pinane (473552) Tetradecane (629594) Tridecane (629505) Undecane (1120214) 1-Butene (106989) 1,3-Cyclopentadiene (542927) 6,6-Dimethyl-2-methylene(lS)bicyclo[3.1.1]heptane (172673) *l-Dodecene (112414) *1-Hexene (592416) 2-Methyl-2-butene (513359) 2-Methyl-1-propene (115117) l-0ctene (111660) 1-Tetradecene (1120367) Hydrocarbons, Aromatic *1,4-Diethylbenzene (105055) 1-Phenyldodecane (123013) 1-Phenyltridecane (123024) 1- Phenylundecane (6742547) Nitriles 2- Hydroxypropanenitrile (78977) 2- Pentenenitrile (26294984) 3- Pentenenitrile (4635874) Organometa11ics Decanol aluminum salt (26303548) Dodecanol aluminum salt (14624158) Octanoi aluminum salt (14624136) Tetradecanol aluminum salt (67905322) Tridodecyl aluminum (1529595) Tris(decyl) aluminum (1726665) [[N,N,-l,2-Ethanediylbis[N-(carboxymethyl)glycinato]](4-)--N,N',0,0' ferrate(l-) (21265509) Tetrakis[tris(methylphenyl)phosphite-P] nickel (T-4) (35884663) ^ 000^8370 Manufactured by CMA member companies not participating in the first phase of the pilot program. -4- Peroxides Bis(1-methyl-1-phenylethyl) peroxide (80443) Phenylenebis(1-methylethylide) peroxide (251552S3) 1-Phenylethy1 hydroperoxide (3071327) Pinanyl hydroperoxide (28324529) Phenols 3-Methy1-4-nitrophenol (2581342) *4-0ctylphenol (1806264) 2,4,6-Trimethylphenol (527606) Phosphorous and Sulfur Acids, Esters and Salts Dibutyl phosphate (107664) Methylphenyl diphenyl phosphate (26444495) Diethyl phosphonate (762049) Tris-(1-chloro-2-propy1) phosphate (13674845) *0,0-Diethyl phosphorochlorodithioate (2524041) 0,0-Diisoocty1 phosphorodithioate, zinc salt (28629665) *0,0-Dimethyl phosphoramidothioate (17321470) *0,0-Dimethyl phosphorochlorodithioate (2524030) Q-(1-Methylethy1) carbonodithioate (140932) Ethenesulfonic acid, sodium salt (3039836) 2, 21-(1,2-Ethenediyl)bis-(5-amino)benzenesulfonic acid (81118) VVV 000028371 Manufactured by CMA member companies not participating in the first phase of the pilot program. CHEMICAL MANUFACTURERS ASSOCIATION REPLY FORM PARTICIPATION IN PHASE II OF THE OECD HIGH PRODUCTION VOLUME EXISTING CHEMICALS TESTING PROGRAM Vista Chemical Company manufactures the following chemical and agrees to take lead responsibility for sponsoring it in the OECD HPV Existing Chemicals Testing Program: 1-Tetradeeanol (112721) ft,irfe1eir'fe`Je4f1t'trte,ir'k-/rje'trir4c/t'4rk'trfr'te1e&ie'k1e1rtrir1r1r1rJr&1rfrtrtr4r1rk1r&'te'k'it1t'trte'ie Vista Chemical Company prefers to use the following option to manage our activities in the OECD HPV Existing Chemicals Testing Program: (please check one) ____ Option A: Our company will take lead responsibility for the chemical listed above, including data collection and testing, and will interact directly with EPA, which serves as the U.S. representative to the OECD. ____ Option B: Our company will take lead responsibility for the chemical listed above, including data collection and testing. We request that CMA establish a CHEMSTAR panel of individual producers of different chemicals to interact with EPA and the OECD on behalf of producers of these different chemicals. (The approximate cost to participants will depend on the number of companies and will be discussed with interested companies.) ____ Option C: Our company is interested in forming a consortium of co-producers of the above chemical to share costs of collecting data and conducting testing. We request that CMA establish a chemical specific panel or augment an existing panel within the CHEMSTAR program. (The approximate cost to participants will depend on the scope of the program and will be determined by CMA and interested companies.) vvv 000028372 CHEMICAL MANUFACTURERS ASSOCIATION REPLY FORM - PAGE 2 PARTICIPATION IN PHASE II OF THE OECD HPV CHEMICALS PROGRAM COMMENTS: fftrk-ffh-irit1riett1rir4ririr-irirftJrk'irir'/rit4r4t4t*4r*r'4rirtr1rtr Vista Chemical Company designates the following individual to serve as the lead representative for our company in th* GECD'program: Name:_______________ ____________ Title: Address: Phone: __________________________________ Fax: __________________________________ This reply form was completed by: Name: Title: Phone: __________________________________ __________________________________ __________________________________ Please return completed reply form by COB Friday, October 26, 1990, to: Sandra L. Tirey Associate Director, Health Programs Chemical Manufacturers Association 2501 M Street, NW Washington, DC 20037 202/887-1274 (phone) 202/887-1237 (fax) VVV 000028373