Document rZX5Vo33rVymEV0X6aNYpnK7
DuPont Company PFOA in Blood Serum Index to EPA Update
AU.9X6 -
Site Name Belle Chambers Works Dordrecht Dordrecht Experimental Station Fayetteville Villers St. Paul Washington Works
Location Sample Date
Charleston, WV
2004
Deepwater, NJ
2005
Netherlands
2005
Netherlands
2000, 2002,2005
Wilmington, DE Fayetteville, NC
France
2005 2004, 2005 2002, 2003, 2005
Parkersburg, WV
2005
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company PFOA in Blood Serum Belle Plant (Charleston, WV) Mechanics (Sampled in 2004) (perform occasional overtime coverage at Washington Works site - Parkersburg, WV)
PFOA
Name Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic
(PPb) 8.14 10.5 49.7 11.8 7.03 30.2 10.4 15.4 21.3 29.9 15.9
Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic
13.5 10.1 39.6 10.9 24.0 23.9 15.1 16.3 15.6 26.0 7.52 13.4 14.3 10.1 27.8
Mechanic
6.23
Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic Mechanic
4.61 21.6 11.9 10.2 18.0 64.8 13.2
Mechanic
10.1
Mechanic Mechanic Mechanic
20.0 34.1 0.5 not quantifiable -1/2 LOQ used for statistics
Mechanic
16.9
Mechanic
9.48
Mechanic
18.6
Count 41
Average 18.01
Median 15.10
Minimum 0.50
Maximum 64.80
Standard Deviation 12.34
Analysis by Exygen Research, State College, PA LOQ = 1 ppb QC duplicates run - average values shown
March 24, 2006 Barbara J. Dawson, CIH, CSP
3
DuPont Company PFOA in Blood Serum Chambers Works (Deepwater, NJ) Recent Hires August - September 2005
I Result (ppb) Exempt - recent hires
Count Average
Median Minimum Maximum
Std Dev Prod Tech / Operator - recent hire
Count Average
Median Minimum Maximum
Std Dev Total Population
Count Average
Median Minimum Maximum
Std Dev
18 18.4 5.74 35.2 11.9 14.5
6 17.29 16.25
5.74 35.20
9.93
8.01 9.56 14.65 10.8 10.7
18 17.3 15.5
8 13.07 12.73
8.01 18.00
3.77
14 14.88 14.58
5.74 35.20
7.09
Analysis by Exygen Research, State College, PA LOQ = 1 ppb QC duplicates run - average values shown
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company PFOA in Blood Serum Dordrecht Works, Netherlands
2005 Samples
---------- PFOA
Job FEP personnel
(PPb) 3209.0
FEP personnel
4111.0
FEP personnel
636.5
FEP personnel
2954.9
FEP personnel
902.4
Count
5
Average
2362.8
Median
2954.9
Minimum
636.5
Maximum
4111.0
Std Dev
1519.5
Maintenance workers
1190.0
Maintenance workers
2548.5
Maintenance workers
1391.5
Maintenance workers
529.5
Maintenance workers
1080.2
Maintenance workers
1209.7
Maintenance workers
1296.1
Count
7
Average
1320.8
Median
1209.7
Minimum
529.5
Maximum
2548.5
Std Dev
609.1
Others ( engineers/lab personnel)
3253.0
Others ( engineers/lab personnel)
75.5
Others ( engineers/lab personnel)
262.9
Others ( engineers/lab personnel)
11387.0
Others ( engineers/lab personnel)
417.9
Others ( engineers/lab personnel)
565.3
Others ( engineers/lab personnel)
601.2
Others ( engineers/lab personnel)
312.0
Others ( engineers/lab personnel)
406.1
Others ( engineers/lab personnel)
134.7
Others ( engineers/lab personnel)
446.4
Others ( engineers/lab personnel)
416.1
Count
12
Average
1523.2
Median
417.0
Minimum
75.5
Maximum
11387.0
Std Dev
3219.1
Job PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator PTFE operator
Total Populataion
---------- PFOA
(PPb)
1262.5
2056.7
1883.0
3774.7
3800.0
3102.0
4418.5
2922.5
3978.0
2104.0
1768.0
802.4
2282.0
1882.0
2977.7
2718.7
5634.0
2856.5
609.9
3415.4
3658.5
4664.7
2985.0
3322.4
519.8
2619.7
1132.2
Count Average Median Minimum Maximum Std Dev
1979.1
28 2683.2 2787.6
519.8 5634.0 1255.3
Count Average
Median Minimum Maximum
Std Dev
52 2201.3 1931.1
75.5 11387.0
1907.5
Analysis by Medizinisches Labor Bremen, Bremen, Germany LOQ = 10 ppb
r
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company
PFOA in Blood Serum
Dordrecht Works. Netherlands Change
Result 2000 Result 2002 Result 2005 from 2002
Name
(PPb)
(PPb)
(PPb)
to 2005
Comments
Teflon polymer operator Teflon polymer operator Teflon polymer operator Teflon polymer operator
1000 4500
1264 402 972 1148
2057 1883 4418 3253
793 1481 3446 2105
no exposure for 2 years due
Teflon polymer operator Teflon polymer operator
397 262 -135 to job change 754 2978 2224
was active in Teflon clean
Teflon polymer operator
13900
5634
out team prior to year 2000
Teflon polymer operator Teflon polymer operator
1600
621 1136
2856 3415
2235 2279
Teflon polymer operator Teflon polymer operator
1400
979 1979 1000 2620
Average
4480
853 2850 1714
Median Minimum Maximum
1600 1000 13900
972 397 1264
2856 262
5634
Standard Deviation n=
5446 5
324 1406 9 11
Maintenance Maintenance Maintenance Maintenance
Average Median
Minimum Maximum Standard Deviation
n=
800 872 1190 318
1506
2548
1042
1110
1391
281
441 1296
855
800 982 1606 624
800 991 1344
800 441 1190
800 1506 2548
0 446 633
14
4
Service section 38 75
FEP operator FEP operator FEP operator FEP operator
Average Median
Minimum Maximum Standard Deviation
n=
4500
4500 4500 4500 4500
0 1
3476
2640 823
2313 2640
823 3476 1356
3
3209 4111 2955
902
2794 3082
902 4111 1356
4
-267 1391
315 79
380
Lab technician
10 000
Lab technician
313
Analysis by Medizinisches Labor Bremen, Bremen, Germany
LOQ = 10 ppb
New method in use for 2002 and 2005 samples
11387 601
lab technician doing most of APFO analysis- checked working method/procedures after 2005 high result
March 24, 2006 Barbara J. Dawson
Page 5 of 10
fo
DuPont Company PFOA in Blood Serum Dordrecht Works, Netherlands Changes over time in workers with 2005 Samples
Name
' Change
Result 2000 Result 2002 Result 2005 from 2002
(PPb)
(PPb)
(PPb)
to 2005
Comments
Engineer
moved from project engineer C8 recovery to day 950 418 function
Total Population Average Total Population Median Total Population Minimum Total Population Maximum Total Population Standard
Deviation n=
3188 1400
38 13900
4320 9
1109 922 313
3476
820 17
2671 2548
75 11387
2369 23
1562
Analysis by Medizinisches Labor Bremen, Bremen, Germany LOQ = 10 ppb New method in use for 2002 and 2005 samples
7
March 24, 2006 Barbara J. Dawson
Page 6 of 10
DuPont Company PFOA in Blood Serum Baseline Samples Prior to Start of Pilot Process (12/04 - 2/05) Experimental Station, Wilmington, DE Telomers Research and Development Work
Count Average
Median Minimum Maximum
Std Dev
Result (PPb)
10.1 23.0 9.45 21.1 276 8.37 10.75 5.19 10.0 5.94 29.2 4.86 4.55 29.7 34.3 4.37
16 30.4 10.1
4.4 276.0 66.26
Analysis by Exygen Research, State College, PA LOQ = 1 ppb QC duplicates run - average values shown
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company PFOA in Blood Serum
Fayetteville Works, Fayetteville, NC
'some baseline samples were collected between campaigns, these samples are shown with the previous dataset
------ 3TTI------ O U I ------ r m ------
Sample Sample Sample
12/04
6/05
12/05
Job
(ppb)
(ppb)
(PPb)
Supervision/Technical
559 556 678
Supervision/Technical
241 279 334
Supervision/Technical
246 291 439
Supervision/Technical
252 225 709
Supervision/Technical
3.06 no sample no sample
Supervision/Technical
9.27
14 12.2
Supervision/Technical
19.8
27.4 no sample
Supervision/Technical 16.1 39 42.1
Supervision/Technical
7.49 no sample no sample
------ a m ------ ------- c m -- 7 I ------------
Sample Sample Sample
12/04*
6/05* 12/05
Job Name APFO Field/
(ppb)
(PPb) (PPb)
CCR Tech APF Held/
128 151 no sample
CCRTech A P F Field/
no sample
440 672
C C R T ech
112 119 130
'F F 'F iir a 7 ------------
CCRTech
51 59.7 no sample
A F F O F ie ld /-----------CCRTech A 'F F T I l) ------------
1743
1780
1990
CCR Tech A P F Field/
CCR Tech APFO Field/
511 685 294 no sample
971 366
CCRTech 'F F T O T
1853
1850
3260
CCRTech APF Field/
1523
1550
1600
Supervision/Technical
6.29
8.65 no sample
Supervision/Technical
9.79 no sample no sample
Supervision/Technical no sample
6.67
7.11
Count Average
11 .
9 7
124.5
160.7
317.3
Median Min
16.1 3.1
39.0 6.7
334.0 7.1
Max
559.0
556.0
709.0
Std Dev Support (wage) Support (wage) Support (wage) Support (wage) Support (wage)
180.3 1057 1653 no sample no sample no sample
191,2 2325 no sample
64 no sample no sample
306.5 4540 no sample no sample 12.6 9.63
Support (wage)
no sample no sample
9.55
Support (wage)
421 409 586
Support (wage)
no sample
58.9 no sample
Support (wage)
no sample
9.72 no sample
Count 3 5 5
Average
1043.7
573.3
1031.6
Median
1057.0
64.0
12.6
Min Max
421.0 1653.0
9.7 2325.0
9.6 4540.0
Std Dev
616,1
992.1
1977.0
Nation Tech Nation Tech Nation Tech
18.7
26.3
27.6
2.89 no sample no sample
. no sample no sample
Nation Tech
7.37 no sample no sample
Count Average
Median Minimum
4 ;1 . 1 9.7 26.3 27.6 8.7 26.3 27.6 2.9 26.3 27.6
Maximum Std Dev
18.7 8.7
26.3
27.6
CCRTech
1897
1320 no sample
APF "Fl'd7
CCR Tech
499 no sample
1200
Count
10
9
8
Average
861.1
8839
1273.6
Median
505.0
685.0
1085.5
Minimum
51.0
59.7
130.0
Maximum
1897.0
1850.0
3260.0
Std Dev
789.0
742.3
1011.1
APFO/Teflon Tech*
24.2
33.4 no sample
APFO/Teflon Tech no sample
8.85
40.8
APFO/Teflon Tech*
7.32
50.3 no sample
APFO/Teflon Tech*
11 20.4 47.9
APFO/Teflon Tech*
3.15
47.9
41.1
APFO/Teflon Tech no sample
17.7 no sample
APFO/Teflon Tech*
10.7
50.5 no sample
APFO/Teflon Tech* 23.2 142 156
Count 6 8 4
Average
13.3
46.4
71.5
Median
10.9
40.7
44.5
Minimum 3.2 8.9 40.8
Maximum
24.2
142.0
156.0
Std Dev
8.6
41.8
, 56.5
samples collected between campaigns highlighted
Total Population Count
Average Median Min
Max Std Dev
34 389.1
37.6 3.1
1897.0
32 395.8
61.9 6.7
2325.0 03.
25 715.3 334.0
7.1 4540.0 TTT3
Analysis by Exygen Research, State College, PA LOQ = 1 ppb QC duplicates run - average values shown
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company PFOA in Blood Serum Villers St. Paul, France Telomers Production
2002-2005
Results Results Results
2002 2003 2005 Difference
Job description (PPb) (ppb) (PPb) 2005-2003
Process operator 5.4 34.2 45
10.8
Process operator 39.6 85.6
77
-8.6
Process operator 52 92.2 73
-19.2
Process operator 37.7 70.2
67
-3.2
Process operator 45
94.5 106
11.5
Process operator 34
92
Process operator
33.9 44
10.1
Process operator
38 52
14
Process operator
26.3 27
0.7
Process operator 33 57.6 65
7.4
Process operator 20.1 62.5
63
0.5
Process operator 14 37.3 36
-1.3
Process operator 22.8 84.1
94
9.9
Process operator
58.8 60
-10.2
Process operator 41.5 80.7
83
2.3
Process operator 8.5 35.6 34
-1.6
Average 29.5 59.4 63.6
4.2
Median 33.5 58.8 64.0
Minimum 5.4
26.3 27.0
Maximum 52.0 94.5 106.0
Std Deviation 15.0 24.0 23.2
n= 12 15 16
Average Median
Minimum Maximum Std Deviation
n=
2005
Entire Population 51.2 51.5 5.0
106.0 28.5
24
Administ. Operator Administ. Operator Administ. Operator Administ. Operator Administ. Operator Administ. Operator
Average Median
Minimum Maximum Std Deviation
n=
10.5
33.5
51 31.7 33.5 10.5 51.0 20.3
3
26.4 6.7 5.8
61 67.2 33.4 26.4 5.8 67.2 29.3
5
26 5 5 48 54 51 31.5 37.0 5.0 54.0 22.8 6
-1.9
Contractor Contractor
Average Median
Minimum Maximum Std Deviation
n=
7.1 9.7 8.4 8.4 7.1 9.7 1.8 2
5 10 12
5.0 11.0 5.0 11.0 5.0 10.0 5.0 12.0 0.0 1.4 12
Analysis by Medizinisches Labor Bremen, Bremen, Germany
LOQ = 10 ppb
(when result < LOQ, 1/2 of LOQ (5) is shown
and used to calculate the descriptive statistics
5
10
March 24, 2006 Barbara J. Dawson, CIH, CSP
DuPont Company PFOA in Blood Serum Washington Works (Parkersburg, WV)
2005 Recent Hires
-PFO TT
(P P b) 65.3 24.7 18.8 139 51.1 51.6 18.6 12.5 19.6 46.9 11.9 582 633 22.1 99.0 19.6 261 279 18.5 257 10.5 117 12.7 365 21.0 13.9 Count 26 Average 121.9 Median 35.8 Minimum 10.5 Maximum 632.9 Std Dev 173.9
Analysis by Exygen Research, State College, PA LOQ = 1 ppb QC duplicates run - average values shown Some workers had previous occupational exposure
II
March 24, 2006 Barbara J. Dawson, CIH, CSP
