Document rK3E2GybybEY9YOMEYvgaa67

Industrial Hygiene Digest * i February, 1956 BOOKS, PAMPHLETS AND NOTICES 176 Handbook ot Toxicology. Vol, 1. Acute Toxicitics. WUliam S. Specter, editor. W. B. Saunders Co., West Washington Square, Philadelphia 5, Pa. 408 pp. <1956). $7.00. This book was prepared under the direction of the Committee on the Handbook ot Biological Data, Division of Biology and Agriculture, The National Academy o Sciences and The National Research Council. W. F. von Oettiogeu Is the principal contributor but a number o( others assisted in the preparation of the volume. The material Is presented in two extensive tables. Table l gives, Information on lethal doses of 2120 solid and liquid compounds to laboratory animals. Under the heading of each substance, listed alphabet ically, are separata entries for each species, route of administration, method of estimating toxicity (LD5q, MUD etc. ) and literature reference from which additional information can be obtained. Table 2 lists lethal concentrations of 243 gases, vapors, and fumes in respired air for laboratory animals. Each entry Includes: animal, method of estimating toxicity, lethal concentration in mg. per liter and parts per million, exposure time, and time of death, when given, and reference. It is emphasized that the values presented in theec tables are. not absolute, and should be interpreted only as a "yardstick" of toxicity for the compounds listed. An index is provided so that materials having more than one name can be easily lo cated. This volume is United to acute toxicides. At least four more volumes, giving Caller coverage of particular classes of materials and including chronic toxicides, will appear later. The scope of this publication and the thoroughness with which the data have been assembled will make it a valuable reference work for the toxicologist and others concerned. -- FFR 177 Organic Insecticides: Their Chemistry and Mode of Action. Robert L. Metcalf. Interscience Publishers, Inc., 250 Fifth Ave., New York 1, N. Y. 392 pp. (1955). $8.50. Despite the amazing growth of the manufacture and use of insecticides, much re mains to be learned regarding their chemistry and mode of action, their metabolism in plants and animals, and their toxic hazards to higher animals. This book summarizes most of the available information on these topics into a coherent pattern dealing with the organic insecticides. Both the older and newer insecticides are included, as Indicated la the list of chapters: nicotine, noruicottne, and anabasine; rotenoids; pyrethrolds; organic thiocyanates: dinitraphenols: DDT: scaricides; benzene hexachloride: cyelodleae Insecticides; organic phos phorus Insecticides; carbamates; and miscellaneous. The chapter on each of these materials includes Information on chemistry, relation of structure to activity, mode of action, and mammalian toxicology the last of which is important in the industrial hygiene field. Two Other chapters deal respectively with joint action of insecticides and insecticide resistance. -- FFR 178 Particle Size Determination. R. D. Cadle. Interscieaee Manual No. 7. Interscience Publishers, Inc., 250 Fifth Ave., New York 1, N. Y. 303 pp. (1955). $5.50. There are many methods for determining particle size, and there is a wealth of literature on those methods. This manual has been written primarily as a guide for a scien tist or engineer who is faced with the task of particle size determination in a particular prob lem or field and is confused by the multitudes of methods. Considerable emphasis is placed on the criteria for choosing a method. The theoretical basis of each method is described, and basic equations are included. The theoretical and practical limitations of the methods are indicated. In the introduction, specific applications are discussed, including the indus trial hygiene field. The topics of the chapters Include: sampling methods; choice of tech nique for particle size determination; Slavs analysis; sedimentation and eiutriation; optical microscopy; alectron microscopy; surface area measurements; optical methods for particles in suspension; miscellaneous methods; and treatment of data. The attention to the various types of .electron microscopes, and to electronic scanning and other recent developments 5. 11 206 1364