Document rBVjzXoEqErJ7jxZDB1p3y2Be

AR226-2886 E. I. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine Elkton Road, Newark, Delaware 19711 Study Initiated/Completed 7/15/80 - 7/17/80 Material Submitted by CD&P Dept. Jackson Lab SKIN IRRITATION TEST ON RABBjlTS Procedure; Six male albino rabbits were clipped free of hair on the trunk and lateral area and placed in FDA-type stocks. Doses of 0.5 g undiluted test material were applied to intact skin under 1 1/2" x 1 1/2" 12-ply gauze s res. Rubber sheeting was then loosely wrapped around the trunk and secured w adhesive tape. After 24 hours, the rabbits were removed from the stocks, che patches taken off and the reactions observed. Observations were also made at 48 hours. Results : 24-Hour Observation Erythema Slight 6/6 Edema None 6/6 48-Hour Observation Erythema None 6/6 Edema None 6/6 Sanitized. Does not contain T S C CBS l S n a * . r y f a | ' a n e e d slight * 1 Irritation In 2 honrs and no Irritation la 48 hodrs w h S ^ e t e d on the shaved intact skin of rabbits. ' Even thoth thin toaponnd tanned only s l i g h t " irritation good industrial hygiene practice would be to wash thoroughly with soap ann event of skin contact. Other Name: Composition of Mixtures by X: Report by: 4'" ,coved b]r! - frE s ria Chiefs Acute Investigations Section PA:jrg Study Director: 0. L. Dashiell " 1980 Report N o 562-80 2- - Company Sanitized. Doss not contain TSCA C m