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* t .* . _-. .-. St. I'at11. MN 55144-1000 651 733 III0 May 23,2003 By Hand Deliverv Document Processing Center (`7407) Office of Polltition, Prevention ilnd Toxics U.S. Environmenta Protection Ageni=y 1200 Pennsylvania Avenue, N. W. Washingtori, DC 20460 Attention: Section 8(e) Coordinator Re: Dear Sir/Mad&n: TSCA Section 8(e) Submissions 3M Company ("3/W') requests that EPA place the attached studies in the .TSCA Section 8(e) docket. We have included an in,dex for these studies identifying the study title, test substance and CAS number. A CBI version of thii index and the studies &o is being submitted today pursuant to EPA procedures. , 3M has concluded that da1;a in the_s-e- s_f_u_d_i@._-s m...a-.y not be, strictly speaking, "corroborative" of previously reported or published information as d_e-f_in..e_d-_ .in.. _FPA's reporting guidance or otherwise potentially may warrant 8(e) submissinn k\Q@odnn EPA's reporting guidance, undersigned submission. 3M appreciates EFA's attention to this matter. Please contact the if you have any questions or require further information regarding this Very truly yours, 2;. , /&l:!< q,,!+; .<I),$ $.. f&j Dr. Katherine .E. Reed, Ph.D Executive Director 3M Environmental Technology And Safety Services (651) 778-4331 kereed@mmm,com *`I (-$$j CQNYXINS NO CONFIDENTIAL BUSINESS,. lNFORMATlON SUBMlSSlON BY 3M ..jbMPANY,ON MAY 23,2003 ;B! removed); 68555!?-!a; 34454-97-2 :xploratory ?&Day Oral Toxicity Study with T`125. T-7126, T-7127, T-7326, and T-7129 by kily Gauge ir, tne Ral Foliosvcd by a 14128.Day iwovery Period (POTOX Project 256679) nlafluormethyi)-, polassium sail (GAS -3) - 66-70%; CyciohexanesuIfonic 75114-42-3; 8756-01-1; 6015G-07-O; 3707-18-4 orobis(lrlftuoromethyi)-, potassium satt (CAS jubchror,ic SO.Day Oral Toxicjty Iaily Gavage in the Rat Followed ieccvery Perioa with T-6524 by by a 2&C&y ?&5-O&2 i Sr~.dy fcr Effecls cfl Embryofoelai :f the Rat (inhalation Administralion) Developmen ?valuation of the Ability of T-5870 to induce >hromosome Aberrations in Cultured Peripheral iuman Lymphocytes (with independent Repeat) ;hromosomal Aberration Test of T-6595 Using >ultured N;ammalian Cells lcute Orai Toxicity Study in Rats (Exp. No. )20584) (Test Article. lntermadio 1249) &He Oral Toxicity Sk~dy in Rats ):3O:i22) (7est Article: 502149) ---- $,cin Corro.ivily S!udy of l-5799 DO-/JN F eyula!ions) (Exe. No. i1.1Rabbits Skin Corrosivity Study Of T-5800 in Rabbits [DOT/UN Regulations) hydrazone: Molecular Formula: CllHli'N302S ctanesulfonyl Fluoride - 87.5%. Olher Aikyt Sultonyl Fluorides and Acidic Impurities - 11%. Water - 5.4%, Octanesulionyl Chloride - 1.4% Suffonyl Fluorides and Acidic Impurities - 1 I%, ;Blremovad] -- ZBi removed] I_Inknown -. ~0630-63-5; `732-18-S; Unknown; 7795-95-i 40630-63-5; ?732.`18-5: Unknown: 7795-95-I &nery Deimal IrritationlCorroston Study of T- !j635 in RaMits (OECD Guidelines) t _. Primary Dermal IrritalionlCorrosion Study of T- 5097 in Rabbits (OECD Guidelines) -..- Sktn Ccrrosi&y Study of T-7030.1 in Rabbits i/~irn ?otcc'~f TP4205 attached) r- Ciermal Sensitization Study of T-5474 in Guinea pigs - Maximization lest (EPA Guidelines) . ..* I lsophthaloylbis (2.methylaniridine) 120/E, Xyiene - 0.5%. - 97%, Toluene II_... 7652-64-4; 133oxl-7 108-88-3; [CBI removed] Water (CAS No. 7732-18-5) - 68A%; -7-7----j Kmoved] `32-l U-5: .27 176-87-D: 1 Dodecylbenzanesulfonic Acid (GAS No. 27176-87-c 25087-26-j; 1310-73-Z - 17.5%; Polymethacrylate (CAS No. 25087-26-7) 11.76%; Sodium Hydroxide (CAS No. 7310-73-2) - 2.3%; Unknown - 0.040% -. i $ONTAlNS NO CONFIDENTIAL BUSINESS INFORMATION SUBMlSSlO.~ BY :3M COMPANY ON MAY 23,2003 Dsrmal Sensitization Study 01 T-5894 in Guinea Pigs - Mc.ximization Test {EC Guidelines) (with Protocol TP6164E attached) Ls3755 Dermal Sensitizelion Study of T-6006 in Guinea Pis;s - Closed Patch Technique (EPA Guidelines) Oimethyltelradecylamine Oxide - 55%. Oleamidopropyldimethyiamine - 18%, l-Melhoxy -2- Propanol - 5%, Ci~ronellol - 5%, Polyethylene Glycol . < 3%, Alpha - (Carboxymethyl) - Omega - (Dodecyloxyi) Poly (Oxyeihylene) Sodium Safl -3%, Trialkyl Amine Oxide - 2%, Isopropyl Alcohol - 2%, Fragrance Sozio SZ 5467 - 2%, Water - `l%, Acetic Acid - I%, Miscellaneous ingredients at iess than 1% 333%.27-2; 109-28-4; 207-98-Z; 106-22-g; 25322-68-3; 33939-64-9; 7128-91-8; 67-63-D: Unknown: 7732-18.5~; 6419-7 I 9sb3- ~3~6 Derrrai Sensllization Sludy of T-7280 in Guinea Pigs . Closed Patch Technique (with Prolocol TP2008 aliached) [GBI removed] [CBI removed] 4cule Oral Toxicity Study of T-6735 in Rats (OECD Guidelines) (with Protocol TP2069 attsched) 4,6-dibromo-2.isopropyl phenol Unknc,wn c\cute Toxici!y to Daphnia Magna !CBi removed] [CEII removed] Eva!uatioc of the Mutagenic Activity of T-5870 in zn In Vitro Mammalian Ceil Gene Mutation Test hilh L5178Y Mouse Lymphoma Cells (with !ndependrnt Repe,atj -_I_ &cu:e Eye lrrilaiion Study in New Zealand While Rabbiis (Exp. No. 920364) (Test Article: 586442. 50055) 2.ethoxy ethyl acrylate riP=!3enzothiazolium (9Cl): SB=3-ethyl-2.((3.(3-(381hyl-2(3H)-benzothiazolylidene)-l-propenyl)-5,53imethyl-2-cyciohexen-l-ylidene)methyl)-6-methoxy5.methyl-; NM=iodide; Molecular Formula: C32H37N20S2.1 106-74-1 .i 8769!L86-3 AcuIe Eye Irritation Study in New Zealand While Rah!i& (Exp. No. 94075'1) (Test Article: 580066) Cicute Eye Irritation Study in New Zeeland White Rabbits (Exp. No. 93C529) (Test Atiicle: 1268) -_I__ Acute Eye irri:ation Study.in New Zealand White Rabbits (Exp. No. 920582) (Test Article: 1248) Thiazolium, 3-eth'yl-2-[3-(3.ethyl-2thiazolidinylidene)-l-propenyl]-4,5-dihydro-,iodide; Moleculai Formula: Cl3HZlN2S2.1 3-elhoxy-carbonyl-methyl-4-eloxy-methylidenerhodanine; Molecular Formula: Cl IIHI 3N04S2 C6H10CIN302S Unkntlwn Unknown One Generation Reproduclion Study of PFOS - fdevalonic AcidlChoiesterol Chailenge.end NOEL inv&tigalion in Rats Perfluorooctane Sulfonic Acid Potassium Salt 279539-3 Rugmenteb acute (4-hour) inhalation toxicity 2% solids of lluorochemical fatty acid esler in water 306g7+, 2;; study with T-6905 in rats