Document qo0jyy5x0bpJmdz01XzRbLRG
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St. I'at11. MN 55144-1000 651 733 III0
May 23,2003
By Hand Deliverv
Document Processing Center (`7407) Office of Polltition, Prevention ilnd Toxics U.S. Environmenta Protection Ageni=y 1200 Pennsylvania Avenue, N. W. Washingtori, DC 20460 Attention: Section 8(e) Coordinator
Re: Dear Sir/Mad&n:
TSCA Section 8(e) Submissions
3M Company ("3/W') requests that EPA place the attached studies in the .TSCA Section 8(e) docket. We have included an in,dex for these studies identifying the study title, test substance and CAS number. A CBI version of thii index and the studies &o is being submitted today pursuant to EPA procedures.
,
3M has concluded that da1;a in the_s-e- s_f_u_d_i@._-s m...a-.y not be, strictly speaking, "corroborative" of previously reported or published information as d_e-f_in..e_d-_ .in.. _FPA's reporting guidance or otherwise potentially may warrant 8(e) submissinn k\Q@odnn EPA's reporting guidance,
undersigned submission.
3M appreciates EFA's attention to this matter. Please contact the if you have any questions or require further information regarding this
Very truly yours,
2;. , /&l:!< q,,!+; .<I),$ $.. f&j
Dr. Katherine .E. Reed, Ph.D Executive Director 3M Environmental Technology And Safety Services (651) 778-4331 kereed@mmm,com
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CQNYXINS NO CONFIDENTIAL BUSINESS,. lNFORMATlON
SUBMlSSlON BY 3M ..jbMPANY,ON MAY 23,2003
;B! removed); 68555!?-!a; 34454-97-2
:xploratory ?&Day Oral Toxicity Study with T`125. T-7126, T-7127, T-7326, and T-7129 by kily Gauge ir, tne Ral Foliosvcd by a 14128.Day iwovery Period (POTOX Project 256679)
nlafluormethyi)-,
polassium sail (GAS
-3) - 66-70%; CyciohexanesuIfonic
75114-42-3; 8756-01-1;
6015G-07-O; 3707-18-4
orobis(lrlftuoromethyi)-,
potassium satt (CAS
jubchror,ic SO.Day Oral Toxicjty Iaily Gavage in the Rat Followed ieccvery Perioa
with T-6524 by by a 2&C&y
?&5-O&2
i Sr~.dy fcr Effecls cfl Embryofoelai :f the Rat (inhalation Administralion)
Developmen
?valuation of the Ability of T-5870 to induce >hromosome Aberrations in Cultured Peripheral
iuman Lymphocytes (with independent Repeat)
;hromosomal Aberration Test of T-6595 Using >ultured N;ammalian Cells
lcute Orai Toxicity Study in Rats (Exp. No. )20584) (Test Article. lntermadio 1249)
&He Oral Toxicity Sk~dy in Rats
):3O:i22) (7est Article: 502149) ----
$,cin Corro.ivily S!udy of l-5799
DO-/JN F eyula!ions)
(Exe. No. i1.1Rabbits
Skin Corrosivity Study Of T-5800 in Rabbits [DOT/UN Regulations)
hydrazone: Molecular Formula: CllHli'N302S
ctanesulfonyl Fluoride - 87.5%. Olher Aikyt
Sultonyl Fluorides and Acidic Impurities - 11%.
Water - 5.4%, Octanesulionyl
Chloride - 1.4%
Suffonyl Fluorides and Acidic Impurities - 1 I%,
;Blremovad]
--
ZBi removed]
I_Inknown
-.
~0630-63-5; `732-18-S;
Unknown; 7795-95-i
40630-63-5; ?732.`18-5:
Unknown: 7795-95-I
&nery Deimal IrritationlCorroston
Study of T-
!j635 in RaMits (OECD Guidelines) t _.
Primary Dermal IrritalionlCorrosion
Study of T-
5097 in Rabbits (OECD Guidelines)
-..-
Sktn Ccrrosi&y Study of T-7030.1 in Rabbits
i/~irn ?otcc'~f TP4205 attached)
r-
Ciermal Sensitization Study of T-5474 in Guinea
pigs - Maximization lest (EPA Guidelines)
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I
lsophthaloylbis (2.methylaniridine)
120/E, Xyiene - 0.5%.
- 97%, Toluene
II_...
7652-64-4; 133oxl-7
108-88-3;
[CBI removed] Water (CAS No. 7732-18-5) - 68A%;
-7-7----j Kmoved]
`32-l U-5: .27 176-87-D:
1
Dodecylbenzanesulfonic
Acid (GAS No. 27176-87-c
25087-26-j; 1310-73-Z
- 17.5%; Polymethacrylate (CAS No. 25087-26-7) 11.76%; Sodium Hydroxide (CAS No. 7310-73-2) -
2.3%; Unknown - 0.040%
-.
i
$ONTAlNS NO CONFIDENTIAL BUSINESS INFORMATION
SUBMlSSlO.~ BY :3M COMPANY ON MAY 23,2003
Dsrmal Sensitization Study 01 T-5894 in Guinea Pigs - Mc.ximization Test {EC Guidelines) (with Protocol TP6164E attached)
Ls3755
Dermal Sensitizelion
Study of T-6006 in Guinea
Pis;s - Closed Patch Technique (EPA Guidelines)
Oimethyltelradecylamine Oxide - 55%. Oleamidopropyldimethyiamine - 18%, l-Melhoxy -2-
Propanol - 5%, Ci~ronellol - 5%, Polyethylene Glycol . < 3%, Alpha - (Carboxymethyl) - Omega -
(Dodecyloxyi) Poly (Oxyeihylene) Sodium Safl -3%, Trialkyl Amine Oxide - 2%, Isopropyl Alcohol -
2%, Fragrance Sozio SZ 5467 - 2%, Water - `l%, Acetic Acid - I%, Miscellaneous ingredients at iess than 1%
333%.27-2; 109-28-4; 207-98-Z; 106-22-g; 25322-68-3; 33939-64-9; 7128-91-8; 67-63-D: Unknown: 7732-18.5~; 6419-7
I
9sb3-
~3~6
Derrrai Sensllization Sludy of T-7280 in Guinea Pigs . Closed Patch Technique (with Prolocol TP2008 aliached)
[GBI removed]
[CBI removed]
4cule Oral Toxicity Study of T-6735 in Rats (OECD Guidelines) (with Protocol TP2069 attsched)
4,6-dibromo-2.isopropyl phenol
Unknc,wn
c\cute Toxici!y to Daphnia Magna
!CBi removed]
[CEII removed]
Eva!uatioc of the Mutagenic Activity of T-5870 in zn In Vitro Mammalian Ceil Gene Mutation Test hilh L5178Y Mouse Lymphoma Cells (with !ndependrnt Repe,atj
-_I_
&cu:e Eye lrrilaiion Study in New Zealand While Rabbiis (Exp. No. 920364) (Test Article: 586442. 50055)
2.ethoxy ethyl acrylate
riP=!3enzothiazolium (9Cl): SB=3-ethyl-2.((3.(3-(381hyl-2(3H)-benzothiazolylidene)-l-propenyl)-5,53imethyl-2-cyciohexen-l-ylidene)methyl)-6-methoxy5.methyl-; NM=iodide; Molecular Formula: C32H37N20S2.1
106-74-1
.i 8769!L86-3
AcuIe Eye Irritation Study in New Zealand While Rah!i& (Exp. No. 94075'1) (Test Article: 580066)
Cicute Eye Irritation Study in New Zeeland White Rabbits (Exp. No. 93C529) (Test Atiicle: 1268) -_I__ Acute Eye irri:ation Study.in New Zealand White Rabbits (Exp. No. 920582) (Test Article: 1248)
Thiazolium, 3-eth'yl-2-[3-(3.ethyl-2thiazolidinylidene)-l-propenyl]-4,5-dihydro-,iodide; Moleculai Formula: Cl3HZlN2S2.1
3-elhoxy-carbonyl-methyl-4-eloxy-methylidenerhodanine; Molecular Formula: Cl IIHI 3N04S2
C6H10CIN302S
Unkntlwn Unknown
One Generation Reproduclion Study of PFOS -
fdevalonic AcidlChoiesterol Chailenge.end NOEL inv&tigalion in Rats
Perfluorooctane
Sulfonic Acid Potassium Salt
279539-3
Rugmenteb
acute (4-hour) inhalation
toxicity
2% solids of lluorochemical fatty acid esler in water 306g7+,
2;;
study with T-6905 in rats