Document qmMVZkDRwr4xd68vVojBDLY8q

Mobil Oil Corporation 1 IAST 4.-NO i 'Ilf f T N(,VV rQIfK. MW 'C0> November 24, 1976 NIOCII Review Ccnmltteo (or PCD Crllcrio Document I discussed Omptcr 3 Effects on Humans of the draft copy of the NIOSH PCD Critoria Dccuronl with Dr. Paul E. Brubaker end with Dr. J. Rodney Meredith, tho Chief Clinician in Paulsboro, New Jersey, for l-lobll Oil Corporation. Dr. Meredith lias been intimately Involved wilh ihe concern about PCB's being carclnogeni c in humans. It was his preliminary report which Dr. Dahn analysed and which wo then forwarded to Dr. Einklca. Since Dr. Meredith was at the Iasi minute unable to attend your mooting, ho would like 1o emphasize by lotlcr a fact for your consideration in preparing tho document. Tho report of data from Mobil which Is died in Ihis documenl was vjice prol Ir.lnary. ifo (eel that this should bo so stated. Dr. Meredith points oul tlie following? TIT" the report was'"b"as"e3"oTmcst~exclusively on a chart soarch; (2) there was no nodical Information avai loble on a large segment of Iho group as Dr. Bahn pointed out; (3) as discussed below there has been a substantial change in the cohort since release of that first report. Fcr thooo roasons Dr. Meredith suspected that Ihe com,position of the cohort was of limited accuracy. Not, however, until we began to identify the cohort moro precisely did wo realize hew difficult was the process of determine exposure and how many changes we would havo to moke. Old records, laboratory nofebooks, personnel records and memories of long service employees for 20 and 25 years ago haj boon consulted, but we began to gain confidence in our cohort only when we resorted to individual interviews with nearly every person possibly associated with PCB's. This process is near completion. Thoro Is still the task of notifying some employees added to tho exposure group and of others deleted from tho exposure group to form Ihe new, basodon-bosl-dota cohort. An extensive examination program has been instituted for both current and former employees. Diagnoses will be veriflod. MQNS 093735 Mobil NIOSH Review Cormittce for PCU CrMcria Document November 2<t, 1976 Pago 2 Thus, It appears that tho change In our cohort will bo considerable and that Iho findings on Ihls new cohort may be si onificantly different from tho preliminary dnfa. Tho information frem Mobil In Iho months ahead may well ham n rii_f forget In-nect than tho preliminary Information which Dr. Uahn analyzed and which Is cl to? ln~~fKTs documont. - A new report will bo made available at tho earliest moment to NIOSH. It should bo ono In which you and all parties concerned will havo confidence. Since re ly BNK/ra B. N. Kightlingor, M.D. Assistant Medical Director HONS 093736