Document qm1GzOmJjj86pNzw75v1kLLLK
FILE NAME: Chemical Abstracts (CHAB) DATE: 1964 DOC#: CHAB048 OCUMENT DESCRIPTION: Abstract Originally Published in 1964 by Enticknap
kovic (Inst. Hyg. Rep. Serbia, Belgrade, Yugoslavia). Arhiv Hig. Rada Toksikol. 11(1), 35-44(1960). Hematological and urinological examn. of galena miners (ore contained PbS 2.54,
ZnS 3.37, CuFeS 0.38, FeAsS 0.58, and FeSj 15.15%) indicated that the level of Pb in blood and urine was approx, the same as
the level among people not exposed to mine dust, 40 y/\. The a
Pb level was higher in inhabitants of a community living in the
vicinity of the mine, 60-220 y/\. The possibility of Pb poison
ing by dissoln. of PbS in gastric juices was demonstrated, but no
clin. case of such poisoning was established.
T. Jurecic
Effects of hair lacquer sprays on the lungs. A. I. G. M e-_
Laughlin, P. L. Bidstrup, and M. Konstam. Food Cosmet.
fibrogenic, with well-established pathology after 4 months. The granular powder provoked a mild foreign-body reaction only, without fibrosis; this is attributable to atm. oxidn. of the surface since this powder is manufd. without lubricant. The lack of pathogenic difference between I and II coated stamped powders may be due to the action of body fluids in pulmonary tissue which
apparently penetrat'. either coating upon prolonged contact. Andrew L. Reeves
Peritoneal tumors in asbestosis. J. B. Enticknap and W. J. Smither (Eastham Mem. Hosp., Essex, Engl.). Brit. J. Ind. Med. 21(1), 20-31(1964). Diffuse abdominal tumors were found in 11 patients with history of asbestos exposure. The extent of
Toxicol. 1(2), 171-88(1963). No abnormal x-ray appearances exposure was often small, and all cases showed remarkably slight
suggesting the presence of thesaurosis (hair spray lung disease) degree of pulmonary fibrosis.
Andrew L. Reeves
were found in 505 hairdressers, of whom 47 were men's hair Blood groups of minerB with coal-workers'pneumoconiosis and
dressers used as controls, exposed to shellac-based hair sprays bronchitis. I. T. T. Higgins, P. D. Oldham, G. S. Kilpatrick,
and/or poly(vinylpyrrolidinone) (PVP)-based sprays for varym* b R. J. Drummond, and B. Bevan (Welsh Natl. School Med.,
periods from less than 1 to 37 years. Particles of hair spray Cardiff, Wales). Brit. J. Ind. Med. 20(4), 324-9(1963). Sur
were small enough to be inhaled and retained in the lungs; in vey of 1250 miners and ex-miners does not support previous
thermal precipitator and konimeter field samples over 95% of speculation that incidence of occupational respiratory disease is
the particles were less than 1 u in diam.; in laboratory samples 88 assoed. with a certain blood group.
Andrew L. Reeves
and 77% of the particles were less than 1 n. Droplets from hand Methyl chloride intoxication. J. D. C. MacDonald (Polymer
sprays were as small as those from pressure sprays. One case" Corp., Sarnia, Can.). J. Occupational Med. 6(2), 81-4(1964).
of thesaurosis (interstitial pulmonary fibrosis with many giant Report of 8 cases showing headache, blurring of vision, loss of
cells and HlOi-Schiff-staining granules in > a woman ex coordination, and reversible personality change involving mo
posed for 11 years to shellac-based hair sprays was reported. 19 roseness, depression, and anxiety. Routine urine and blood tests
references.
D. M. Greninger have no diagnostic value.
Andrew L. Reeves
Arsine poisoning in a slag-washing plant. M. D. Kipling and A follow-up study of lead workers. I. Dingwall-Fordyce and
R. Fothergill (H. M. Med. Insp. Factories, Birmingham, Engl.). 1 R. E. Lane (Univ. Manchester, Engl.). Brit. J. Ind. Med.
Brit. J. Ind. Med. 21(1), 74-7(1963). During the washing of 20(4), 313-15(1963). Retired workers with history of Pb ex
fluorspar slag (As content 10-15 p.p.m.) in the course of A1 metal posure show increased mortality attributable to cerebrovascular
recovery from scrap, AsHj was released into the surrounding atm. incidents but not to neoplasia.
Andrew L. Reeves
at a level of 5 p.p.m. Poisoning occurred in 5 workers, char Hazardous lead exposures among structural-steel workers.
acterized by hemoglobinuria, hemolytic anemia, and jaundice. - Heinrich G. Brugsch (Commonwealth of Massachusetts, Bos
As content (by activation analysis) in hair was 0.23-0.40, and in ton). New Engl. J. Med. 270, 211(1964). Cases of Pb poison
nails, 1.66-2.50 p.p.m. in 2 subjects. The scrap did not contain ing or abnormally high Pb excretion in the urine occurred among
As in excess of 10 p.p.m.
Andrew L. Reeves workers engaged in burning, with acetylene torches, bridge struc
Byssinosis in the Egyptian cotton industry; change in ventila tures that had received paint contg. Pb and among bridge workers
tory capacity during the day. M. A. El Batawi, R. S. F. Schill engaged in spray painting.
Marion Horn Peskin
ing, F. Valie, and Joan Walford (High Inst. Publ. Health, < Working conditions with the blowing agent, ChKhZ-5. M. V.
Alexandria, Egypt). Brit. J. Ind. Med. 21(1), 13-19(1964). Aldyreva. Vestn. Tekhn. i Ekon. Inform. Nauchn.-Issled.
Mean dust concn. at work (in mg./m.1), incidence of byssinosis Inst. Tekhn.-Ekon. Issled. Gos. Kom. Sot. Min. SSSR po Khim.
(%), the initial mean adjusted indirect max. breathing capacity 1962(7-8), 152-5. Gaseous decompn. products, including HS,
(I.M .B.C.), and change of the latter during a workday (both in SOj, org. S compds., aromatic amines, and MeOH, are generated
l./m in.) in different groups of 99 male workers of a cotton ginnery - .by heating the blowing agent ChKhZ-5 in both a pure form and
and spinning mill are resp., as follows: ginners, 15.3, 33, 106.5, as an ingredient of a rubber mixt. The max. permissible concn.
and --7.9; manual mixers, 34.0, 50, 105.6, and --8.2; starting- of ChKhZ-5 dust in the air of working areas is 0.005 mg./m*.
process blowers, 9.4, 25, 122.7, and --9.8; end-process blowers, To improve working conditions in manuf. of porous rubber,
1.9, 10, 122.5, and --2.8; carders, 4.2, 43, 114.4, and --14.2; ChKhZ-5 should be replaced with another less toxic blowing
and power station workers, 0, 0, 124.1, and 4-1.9. Byssinotic agent. From Ref. Zh., Khim. 1963, Abstr. No. 111251.
workers showed consistently larger daily inhibition than un
MVRK
afflicted workers in all occupational groups. The av. I.M.B.C. Effect of unithiol and Ca di-Na ethylenediaminetetraacetate on
for all byssinotics was 106.7, for normal cotton workers 116.8, trace element excretion. A. S. Vakhnitskii. Gigiena i Fiziol.
and for the power-station workers, 126.3 l./min. Safe limit of Truda, Proizv. Toksikol., Klinika Prof. Zabolevanii (Kiev: Gos.
dustiness in cotton gins and mills is 1 mg./m.*; the general atm. Izd. Med. Lit. Ukr. SSR) Sb. 1963, 176-8. Treatment of 71
pollution of the surrounding area plays no role.
patients with chronic heavy-metal poisoning with unithiol (I)
Andrew L. Reeves ` "and Ca di-Na ethylenediaminetetraacetate (II) considerably
Hazard to production workers handling estrogens. H. Kneidel increased excretion of Cu++ and Mn++ in the urine. During
(Berlin-Chem., Berlin-Adlershof, Ger.). Zentr. Arbeitsmed. treatment with I and II the trace element content in the diet
Arbeilsschulz 13(12), 285-6(1963). A fine dust of stilbestrol and should be increased. From Ref. Zh., Biol. Khim. 1963, Abstr.
(or) of related compds. is created during drying, confection No. 21F1974.
MVRL
ing, and packaging of estrogens. Endocrine disorders were ob Subacute and chronic intoxication of workers with trichloro
served in exposed workers, including gynecomastia in men and ethylene in the production of caprolactam. V. A. Antonyu-
menstrual disturbances in women. Both sexes excreted estrogen zhenko, I. M. Kashtanova, R. G. Khil, and V. N. Trefilov.
in the urine. Control measures arc discussed.
Prom. Toksikol. i Klinika Prof. Zabolevanii, Khim. Etiol. (Mos
Andrew L. Reeves cow: Gos. Izd. Med. Lit.) Sb. 1962, 276-8. The nature of
Aluminum pneumoconiosis. I. In vitro comparison of subacute and chronic intoxication with trichloroethylene (I)
stamped aluminum powders containing different lubricating, - in the manuf. of caprolactam (content of I in air 0.01-0.05 mg./l.,
agents and a granular aluminum powder. B. Corrin (Univ. max. permissible concn. 0.01) was studied. Besides I, cyclo
Manchester, Iingl.). Brit. J. Ind. Med. 20(4), 264-7(1963). hexanone, cyclohexanone oxime, SOi, and NHj, whose concns.
Powdered A1 is available as granules produced from molten did not exceed the max. allowable but increased the toxicity of I,
metal, or as flakes produced by stamping process. The latter were found. Thirteen of 150 workers exhibited symptoms of
are coated with stearin (I) or with mineral oil (II) used as lubri chronic intoxication with I. For all 13, urinary trichloroaeetic
cants; atm. oxidn. to AliOj is equally prevented by I and II but acid amounted to 68-210 mg./l. Trichloroethanol was absent.
reaction with HsO to Al(OH)j + Hj is prevented by I only. In From Ref.Zh., Khim. 1963, Abstr. No. 151275.
MJRK
the course of 72 hrs. in vitro, up to 89% of the II-coated powder Accumulation of lead in the workers of lead-zinc mines and
reacted in this manner (vs. none of I-coated powder). This reac concentration plants. A. A. Kasparov. Tr. Tadzhiksk. Med.
tion may be involved in the fibrogenicity of A1 in humans; II- Inst. 51, 53-7(1961). During examn. of 51 workers (21 women
coated flakes appear to be most productive of A1 pneumoconiosis, and 30 men), occupied in operations on flotation and crushing of
while dusts of AliOj or of AljOj-coated A1 are inert. Thera *ore, increased content of Pb in urine (for 41 persons to 0.05 mg./
peutic forms of A1 (for the management of silicosis) belong in the 1., for 10 persons >0.05 m g./l.) was noted. The content of
latter category. II. Effect on the rat lung of intratracheal in hemoglobin, erythrocytes and leukocytes in blood remained in
jections of stamped aluminum powders containing different the normal range. From Ref. Zh., Khim. 1963, Abstr. No.
lubricating agents and of a granular aluminum powder. Ibid. 151260.
MJRK
268-76. Stamped A1 powders, either acetone-washed (lubri t Toxicology of quinone. T. M. Osina. Prom. Toksikol. i
cant-free), or contg. 0.2% of either I or II (47% 1-5 u diam., the Klinika Prof. Zabole-vanii, Khim. Etiol. (Moscow: Gos. Izd.
rest mainly smaller), and granular A1 powder (11% 1-5 u diam., Med. Lit.) Sb. 1962, 137-9. Effects of doses of quinone (I)
the rest larger) were intratracheally injected, in doses of 100 mg. vapors on mice were detd. The L.D.ioo was 0.32-0.34 mg./l.
in 1 ml. sterile saline, into 17-37 rats. All 3 varieties of the (for a 2-hr. exposure). The smallest concn. causing changes of
stamped powder proved to be highly and about equally the central nervous system of mice was 0.04 mg./l. Irritating