Document qkveGGa3j5qea5QNn6bJ7REkG

I PAC International Pharmaceutical Aerosol Consortium ipacinhaler.org I February 2022 IPAC Member Survey on European Manufacture and Export of HFC MD's - Sharing Insights IPAC HFC MDI Survey -- Background and Methods In 4Q 2021, the International Pharmaceutical Aerosol Consortium (IPAC) conducted a survey of its member companies regarding the manufacture of HFC MDIs in the European Union, including volumes imported and exported. In light of commercial sensitivities and to respect competition laws, the IPAC Secretariat collected the data from individual companies and held it in strict confidence. This document summarises the compiled, aggregate survey responses from IPAC members. All data refers to calendar year 2020. Please note that while the data does not include information from companies that are not members of IPAC, we believe that still provides useful insights and is representative of the European market. IPAC members represent a significant portion of the EU market for MDIs. We hope this data is helpful for European policymakers. The survey includes data from the following IPAC members: AstraZeneca Boehringer Ingelheim Chiesi Farmaceutici GSK Kindeva Teva Overview The EU is a global manufacturer of medical inhalers and revising the F-Gas regulation has bearing on the supply of these life-saving medicines to countriesfar outside of Europe. This is an important consideration for policymakers. As detailed below, th e survey shows that approximately 75% of MDIs manufactured in the EU were exported. 75% 4,570,000 MDIs IMPORTED into the EU 349,000,000 MDIs MANUFACTURED in the EU 265,400,000 MDIs EXPORTED from the EU Total IPAC Member Company MDIs in EU: 88,170,000* Details on the 265,400,000 MDIs Exported from the EU North America 26% About IPAC IPAC's mission is to ensure that environmental policies relevant to inhaled therapies are patient-centric and appropriately balance both patient care and sustain ability objectives. For details, see: www.ipacinhaler.org. Please contact the IPAC Secretariat, Maureen Hardwick, with any questions at acinhaler.or or * This figure represents the respondents' totalquantity ofMDIs manufacturedin the EUminus net exports.