Document qkZ8jgDXyX7GZjmKGBvy42KwK

3M Katherine E . Reed, Ph .D . 3M Environmental, Health and 900 Bush Avenue, Buildirpg'4-2E-26 Siaff Vice President Safety Operations PO Box 3333 1 3 731 St . Paul, MN 55133-333 1 651 778 433 1 / -{ ~ e F. F~ o ui 4 F ., ~ Certified Mail D '$z-~q- June 29, 2006 CON 1AIN NO C B 1 Document Processing Center EPA East - Room 6428 Attn : Section Office of Pollution Prevention and Toxic s US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-000 1 No CBI 8(e) v RE : TSCA 8(e) ADDITIONAL INFORMATION SUBMISSION : Docket No . 8EHQ-1200-1483 7 Dear Sirs : In December of 2000, 3M submitted a draft report of a mortality study of 3M employees at a perfluorooctanesulfonyl fluoride (POSF)-based fluorochemical manufacturing facility under the above-referenced docket number . We provided the final report of that study in September of 2001 . Because that mortality study showed an excess of bladder cancer in workers, 3M followed up by commissioning the University of Minnesota to conduct an incidence study . In April of 2005 we submitted a final report on the study examining the incidence of bladder cancer, which did not show an excess incidence of bladder cancer in workers . In addition to following up on the bladder cancer incidence finding, the University of Minnesota also looked at incidence of other health endpoints in the workers at the (POSF)based fluorochemical manufacturing facility . We enclose a copy of the final report on the endpoints other than bladder cancer, entitled "Self-Reported Medical Conditions i n Perfluorooctanesulfonyl Fluoride Manufacturing Workers," by Bruce Alexander and Mira Grice of the School of Public Health at the University of Minnesota (February 1, 2006) (hereafter the "Decatur health study") . In the Decatur health study, current and former workers self-reported health conditions on a questionnaire . The questionnaire asked about several kinds of cancer in addition to bladder cancer, and the researchers verified the responses with medical records or death certificates . The questionnaire also inquired about pregnancy history . This study found no associations between working in a POSF-exposed job and any of the surveyed conditions, including breast, colon, liver, prostate and thyroid cancer, melanoma, gastric ulcer, cystitis, urinary calculi, colon polyps, cholecystitis and cholelithiasis, liver disease, benign prostate hyperplasia, or prostatitis . No association was observed between _ .. p. 2 ' worker exposure from POSF-based fluorochemical production prior to pregnancy and birth weight of workers' newborn babies . Please contact Dayna Blomquist at 651-736-5413 should you have any questions or if we can provide additional information . Sincerely, 2 Katherine E . Reed Staff Vice President Environmental, Health and Safety Operations Enclosure