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FILE NAME Talc TALC DATE 1973 DOC TALC121 DOCUMENT DESCRIPTION Medical Journal - Letter to the Editor Referencing Related Stomach Cancer ticle physics solid physics and who knows what else are relevant to our needs in this respect and are there- fore deserving of public support Nothing is more primitive than our means of generating power either by building a fire or even worse by starting a fission reaction no part of our technology is more ripe for a scientific revolution New science can change our lives in highly desirable ways There have been many notable examples in the past and it does not make sense to behave as though it would never happen again FREDERICK J. HOOVEN Thayer School of Engineering Dartmouth College Hanover New Hampshire 03755 Diet and Stomach Cancer In his interesting report treated rice and Japanese stomach cancer 17 Sept. p 1141 R. R. Merliss advances data indicating that asbestos fiber con- tained in talc added to rice as a flavor fixative is the carcinogenic agent that causes a high incidence of stomach cancer in Japan He suggests that the diets of Finland Iceland and Chile where the incidence is similarly high should be scanned for asbestos contaminants Being familiar with the dietary habits of the Scandinavian countries par- ticularly Finland I believe that the high incidence of stomach cancer there is connected with methods of fish preser- vation Great quantities of strongly salted fish smoked fish and smoked cereal powders talkkuna are con- sumed in these countries I am not aware that any asbestos fibers find their way into foods in Finland and Iceland JOHAN BJORKSTEN Bjorksten Research Foundation Madison Wisconsin 53701 I presume that the talc content which Merliss found was for rice that had been ashed from a ever no respecting serves raw rice She raw state How- Japanese woman rinses it many times in both cold and tepid water until the rinse becomes clear At this stage she adds a final measure of water and either directly cooks it or uses a rice cooker The thorough rinsing prep- arations certainly must remove a great deal of the contaminated talc fibers possibly lowering the content to an insignificant amount 474 May I suggest that a similar study be made in which thoroughly rinsed rice and then cooked rice are used Different amounts of talc and asbestos may be found The connection between rice eating and stomach cancer however may ac- tually exist Boiled white rice is bland and in any country where rice is a staple something has been developed to add to its flavor In India it is curries in Korea and Thailand hot and gar- licky spices the Japanese use soy sauce pickles and some commercial gravies to say nothing of seaweed nori I would look for the cause of Japanese stomach cancer in ) soy sauce which is used in tremendous quantities and in which there is ample opportunity for fungi to grow and produce aflatoxins ii the wide variety of pickles and pickled vegetables that are eaten with the rice iii seaweed which is extensively consumed by the Japanese and iv the method of rice storage which could result in the growth of fungi and the production of aflatoxins in the rice These may or may not be blind al- leys but they are more reasonable than the assumption that the Japanese eat raw rice MELVIN R. SMITH International Division Becton Dickinson and Company Rutherford New Jersey 07070 Merliss's arguments and conclusions seem deceptively evident However there are two major flaws in his theory First most of the rice sold in Japan does not have a talc coating No Japanese home is far from a rice shop and much of the rice is never stored but moves quickly from the field to the consumer In most instances the bran is removed just prior to sale in the shops Second if talc used the method of preparation used by the Japanese involves prolonged washing prior to cooking instructions on bags of glucose and covered rice packed in California by the Japan Food Corporation clearly indicate that the rice should be washed before using It would therefore seem that the amount of talc ingested by the Japanese is negligible and thus not likely to be related to the high prevalence of stomach cancer in Japan K. TAKANO JAMES R. MILLER Faculty of Medicine Department of Paediatrics University of British Columbia Vancouver 8 Canada The talc used to coat the rice that Merliss analyzed may have been Cali- fornia talc which contains about 20 to 40 percent tremolite calcium magnesium silicate a form of asbestos However talc is suitable for human consumption provided that it is nearly all hydrous magnesium silicate and contains only traces of calcium silicate California talc or talc of a similar quality should not be used to dust foods or in medicines Baby products also contain large quantities of talc The amount of talc used in the care of a baby can be estimated at 2 ounces per week per baby Although only a small portion of this quantity is inhaled or swallowed by the baby we should not underestimate the amount The frequency of respiration is very high An additional warning should be made against the use in baby products of talc with a high calcium silicate content R. R. F. GoOVAERTS Ergo's Laboratory 2550 Kontich Belgium Miller and Smith make the point that washing would remove the asbestos- contaminated talc from treated rice I have not found this to be true Examination on 19 October 1971 of rice that was cooked and canned in Japan and sold here in a Japanese market showed 1.1 ^ 10 asbestos- form fibers per gram of desiccated cooked rice Apparently washing and cooking reduces the amount of asbestos- form fibers in rice but does not free it of these fibers Miller says that most rice in Japan moves directly from the field to the consumer It is hard to believe that this is so in metropolitan areas and it is obviously not the case with the Japanese canned rice I ex- amined In all circumstances the inci- dence of stomach cancer in Japan varies from area to area and differences in the nature of the rice might be one of the factors influencing this variation Bjorksten writes that he does not know of talc additives to food in Finland a country where the incidence of stomach cancer is high The problem is complex Talc is usually considered so innocuous that specific inquiry or examination must be made to determine its presence as a food additive Firm information about talc additives is needed from Finland Chile and Ice- land R. R. MERLISS 8820 Wilshire Boulevard Beverly Hills California 90211 SCIENCE VOL 175 1973 1973